BG105163A - Използване на аналог на валпроева киселина за лечение и профилактика на мигрена и афективни заболявания - Google Patents

Използване на аналог на валпроева киселина за лечение и профилактика на мигрена и афективни заболявания

Info

Publication number
BG105163A
BG105163A BG105163A BG10516301A BG105163A BG 105163 A BG105163 A BG 105163A BG 105163 A BG105163 A BG 105163A BG 10516301 A BG10516301 A BG 10516301A BG 105163 A BG105163 A BG 105163A
Authority
BG
Bulgaria
Prior art keywords
treatment
acid
valproyic
prophylaxation
migran
Prior art date
Application number
BG105163A
Other languages
English (en)
Other versions
BG63744B1 (bg
Inventor
Heinz Nau
Emer Leahy
Alan O'connell
Original Assignee
American Biogenetic Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Biogenetic Sciences, Inc. filed Critical American Biogenetic Sciences, Inc.
Publication of BG105163A publication Critical patent/BG105163A/bg
Publication of BG63744B1 publication Critical patent/BG63744B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретението се отнася до подобрен метод за лечение и профилактика на мигрена и афективни заболявания през прилагане на ефективно количество аналог на валпроевата киселина 2-n-пропил-4-хексинова киселина. Съединението е ефективно антимигренозно и противоафективно средство с намалени странични ефекти като невротоксичност и тератогенност.
BG105163A 1998-06-22 2001-01-17 Използване на аналог на валпроева киселина за лечение и профилактика на мигрена и афективни заболявания BG63744B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9028198P 1998-06-22 1998-06-22
PCT/US1999/014081 WO1999066920A1 (en) 1998-06-22 1999-06-22 The use of valproic acid analog for the treatment and prevention of migraine and affective illness

Publications (2)

Publication Number Publication Date
BG105163A true BG105163A (bg) 2002-03-29
BG63744B1 BG63744B1 (bg) 2002-11-29

Family

ID=22222101

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105163A BG63744B1 (bg) 1998-06-22 2001-01-17 Използване на аналог на валпроева киселина за лечение и профилактика на мигрена и афективни заболявания

Country Status (19)

Country Link
US (2) US6268396B1 (bg)
EP (1) EP1089725A1 (bg)
JP (1) JP2002518442A (bg)
KR (1) KR20010071572A (bg)
CN (1) CN1310622A (bg)
AU (2) AU752192B2 (bg)
BG (1) BG63744B1 (bg)
BR (1) BR9911421A (bg)
CA (1) CA2335641A1 (bg)
CZ (1) CZ20004833A3 (bg)
HU (1) HUP0102456A3 (bg)
IL (1) IL140415A0 (bg)
MX (1) MXPA00012808A (bg)
NO (1) NO20006506L (bg)
PL (1) PL345364A1 (bg)
SK (1) SK19992000A3 (bg)
TR (2) TR200003800T2 (bg)
WO (1) WO1999066920A1 (bg)
ZA (1) ZA200007652B (bg)

Families Citing this family (15)

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Publication number Priority date Publication date Assignee Title
US6104802A (en) 1997-02-10 2000-08-15 Genesys Telecommunications Laboratories, Inc. In-band signaling for routing
PT1181012E (pt) * 1999-05-04 2005-02-28 Keith R Edwards Valproato intravenoso para tratamento de enxaqueca aguda
CN1251758C (zh) 2000-07-21 2006-04-19 特瓦制药工业有限公司 丙戊酸和2－丙基戊烯酸酰胺的衍生物在制备治疗双极情感障碍症躁狂病药物中的用途
IL154470A0 (en) * 2000-08-17 2003-09-17 Teva Pharma Use of derivatives of valproic acid amides and 2-valproenic acid amides for the treatment or prevention of pain and/or headache disorders
US20020103110A1 (en) * 2001-01-26 2002-08-01 Spitzer A. Robert System and method for rectal administration of medication for treatment of migraines
US7968569B2 (en) * 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
US20060247216A1 (en) * 2002-10-25 2006-11-02 Haj-Yehia Abdullah I Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
US20060166894A1 (en) * 2002-11-29 2006-07-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ace-inhibitors having antioxidant and no-donor activity
CA2508855A1 (en) * 2002-12-16 2004-07-01 Frank Slade Abbott Valproic acid analogues and pharmaceutical compositions thereof
EP1543831A1 (en) * 2003-12-18 2005-06-22 Pfizer GmbH Arzneimittelwerk Gödecke Pregabalin composition
WO2006012603A2 (en) * 2004-07-22 2006-02-02 Nps Pharmaceuticals, Inc. Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
WO2007028030A2 (en) * 2005-09-02 2007-03-08 Picobella, Llc Oncogenic regulatory rnas for diagnostics and therapeutics
US7459280B2 (en) * 2006-02-27 2008-12-02 Picobella, Llc Methods for diagnosing and treating kidney cancer
US20080267977A1 (en) * 2007-04-26 2008-10-30 Friedrich-Alexander University Of Erlangen-Nuremberg Combined immunological agent and sensitizing agent for the treatment of cancer
CA2872976A1 (en) * 2012-05-08 2013-11-14 Cellixbio Private Limited Compositions and methods for the treatment of neurological disorders

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FR2442M (fr) 1962-10-17 1964-04-06 Henry Eugene L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.
US3701729A (en) 1970-06-01 1972-10-31 Tenneco Chem Oil-soluble mixed copper soap products
US3847956A (en) 1973-04-06 1974-11-12 Us Agriculture 2-hydroperoxycarboxylic acids and their preparation
US3932285A (en) 1973-10-03 1976-01-13 Tenneco Chemicals, Inc. Chromium salt compositions and a process for their production
US4025649A (en) 1974-08-19 1977-05-24 Labaz Acetic acid derivatives having pharmacological activity and compositions containing the same
US4129599A (en) 1975-04-28 1978-12-12 The Board Of Trustees Of Leland Stanford Jr. University A-Norsteroids
JPS5680116A (en) 1979-12-05 1981-07-01 Sanyo Electric Co Ltd Manufacture of substrate for magnetic bubble
JPH0233704B2 (ja) 1982-10-07 1990-07-30 Takeda Chemical Industries Ltd Chikanbinirukarubonsanjudotai
FR2599737B1 (fr) 1986-06-10 1989-05-19 Sanofi Sa Procede pour la fixation de groupes alkyles, alkenyles, cycloalkyles ou aralkyles sur une chaine carbonee portant un groupement fonctionnel
JPH01135740A (ja) 1987-11-24 1989-05-29 Nippon Mining Co Ltd 光学活性を有する２―アルキル―１―アルカン酸の製造方法
US5021398A (en) 1989-10-26 1991-06-04 Amp Incorporated Method of forming patterned oxide superconducting films
US5102913A (en) * 1991-07-01 1992-04-07 Halikas James A Treatment for cocaine use employing valproic acid
DE4231085A1 (de) * 1992-09-12 1994-03-17 Desitin Arzneimittel Gmbh VPA-analoge Antiepileptika
CA2144081C (en) 1992-09-16 2004-11-30 Filip Roos Protection against liver damage by hgf
CA2148101C (en) 1992-11-30 1999-04-20 Phillip Kyle Vinson High sudsing detergent compositions with specially selected soaps
JP3304459B2 (ja) 1992-12-18 2002-07-22 松下電器産業株式会社 電解コンデンサ駆動用電解液およびそれを用いた電解コンデンサ
DK0632008T3 (da) 1993-06-01 1998-09-23 Ono Pharmaceutical Co Pentansyrederivater
US5503830A (en) 1993-09-10 1996-04-02 Petrovax, L.L.C. Compounds having immunostimulating activity and methods of use thereof
WO1995033044A1 (en) 1994-05-27 1995-12-07 The Procter & Gamble Company Liquid laundry detergent compositions comprising specially selected soaps
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IT1283489B1 (it) 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico

Also Published As

Publication number Publication date
AU4707199A (en) 2000-01-10
US6268396B1 (en) 2001-07-31
CN1310622A (zh) 2001-08-29
US6458840B2 (en) 2002-10-01
NO20006506L (no) 2001-02-21
WO1999066920A1 (en) 1999-12-29
AU5207199A (en) 2000-01-24
PL345364A1 (en) 2001-12-17
HUP0102456A2 (hu) 2001-10-28
TR200103249T2 (tr) 2002-05-21
US20010031789A1 (en) 2001-10-18
JP2002518442A (ja) 2002-06-25
TR200003800T2 (tr) 2001-06-21
IL140415A0 (en) 2002-02-10
CA2335641A1 (en) 1999-12-29
MXPA00012808A (es) 2002-04-24
AU752192B2 (en) 2002-09-12
SK19992000A3 (sk) 2001-08-06
BG63744B1 (bg) 2002-11-29
BR9911421A (pt) 2001-03-27
ZA200007652B (en) 2002-03-19
NO20006506D0 (no) 2000-12-20
KR20010071572A (ko) 2001-07-28
CZ20004833A3 (cs) 2002-01-16
HUP0102456A3 (en) 2003-07-28
EP1089725A1 (en) 2001-04-11

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