NO20006506L - Anvendelse av valproinsyreanalog for behandlingen og forebyggelsen av migrene og affektive sykdommer - Google Patents
Anvendelse av valproinsyreanalog for behandlingen og forebyggelsen av migrene og affektive sykdommerInfo
- Publication number
- NO20006506L NO20006506L NO20006506A NO20006506A NO20006506L NO 20006506 L NO20006506 L NO 20006506L NO 20006506 A NO20006506 A NO 20006506A NO 20006506 A NO20006506 A NO 20006506A NO 20006506 L NO20006506 L NO 20006506L
- Authority
- NO
- Norway
- Prior art keywords
- migraine
- valproic acid
- affective
- prevention
- acid analog
- Prior art date
Links
- NIJJYAXOARWZEE-UHFFFAOYSA-N Valproic acid Chemical class CCCC(C(O)=O)CCC NIJJYAXOARWZEE-UHFFFAOYSA-N 0.000 title abstract 4
- 208000017194 Affective disease Diseases 0.000 title abstract 3
- 208000019695 Migraine disease Diseases 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title 1
- AAFSOWLNAOPEQF-UHFFFAOYSA-N 2-propylhex-4-ynoic acid Chemical compound CCCC(C(O)=O)CC#CC AAFSOWLNAOPEQF-UHFFFAOYSA-N 0.000 abstract 2
- 206010029350 Neurotoxicity Diseases 0.000 abstract 1
- 206010044221 Toxic encephalopathy Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 230000002460 anti-migrenic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 230000007135 neurotoxicity Effects 0.000 abstract 1
- 231100000228 neurotoxicity Toxicity 0.000 abstract 1
- 231100000378 teratogenic Toxicity 0.000 abstract 1
- 230000003390 teratogenic effect Effects 0.000 abstract 1
- 229960000604 valproic acid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Foreliggende oppfinnelse omhandler en fremgangsmåte for behandling og forebygging av migrene og affektive sykdom ved administrering av en terapeutisk effektiv mengde av valproinsyre-analogen 2-n-propyl-4-heksynsyre. For- bindelsen 2-n-propyl-4-heksynsyre er et effektivt anti- migrene og anti-affektivt sykdomslegemiddel med svært reduserte ugunstige virkninger inkludert nevrotoksisitet og teratogent potensiale sammenlignet med valproinsyre. Fore- liggende oppfinnelse gir derfor en forbedret fremgangsmåte for å behandle og forebygge migrene og affektiv sykdom.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9028198P | 1998-06-22 | 1998-06-22 | |
| PCT/US1999/014081 WO1999066920A1 (en) | 1998-06-22 | 1999-06-22 | The use of valproic acid analog for the treatment and prevention of migraine and affective illness |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20006506D0 NO20006506D0 (no) | 2000-12-20 |
| NO20006506L true NO20006506L (no) | 2001-02-21 |
Family
ID=22222101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20006506A NO20006506L (no) | 1998-06-22 | 2000-12-20 | Anvendelse av valproinsyreanalog for behandlingen og forebyggelsen av migrene og affektive sykdommer |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6268396B1 (no) |
| EP (1) | EP1089725A1 (no) |
| JP (1) | JP2002518442A (no) |
| KR (1) | KR20010071572A (no) |
| CN (1) | CN1310622A (no) |
| AU (2) | AU752192B2 (no) |
| BG (1) | BG63744B1 (no) |
| BR (1) | BR9911421A (no) |
| CA (1) | CA2335641A1 (no) |
| CZ (1) | CZ20004833A3 (no) |
| HU (1) | HUP0102456A3 (no) |
| IL (1) | IL140415A0 (no) |
| MX (1) | MXPA00012808A (no) |
| NO (1) | NO20006506L (no) |
| PL (1) | PL345364A1 (no) |
| SK (1) | SK19992000A3 (no) |
| TR (2) | TR200003800T2 (no) |
| WO (1) | WO1999066920A1 (no) |
| ZA (1) | ZA200007652B (no) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6104802A (en) | 1997-02-10 | 2000-08-15 | Genesys Telecommunications Laboratories, Inc. | In-band signaling for routing |
| ES2228521T3 (es) * | 1999-05-04 | 2005-04-16 | Keith R. Edwards | Valproato intravenoso para el tratamiento agudo de la jaqueca. |
| NZ523917A (en) * | 2000-07-21 | 2004-11-26 | Teva Pharma | Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder |
| DK1311256T3 (da) * | 2000-08-17 | 2005-11-28 | Teva Pharma | Anvendelse af derivater af valproinsyreamider og 2-valproinsyreamider til behandling eller forebyggelse af smerter og/eller hovedpinelidelser |
| US20020103110A1 (en) * | 2001-01-26 | 2002-08-01 | Spitzer A. Robert | System and method for rectal administration of medication for treatment of migraines |
| US7968569B2 (en) * | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
| US20060247216A1 (en) * | 2002-10-25 | 2006-11-02 | Haj-Yehia Abdullah I | Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments |
| WO2004050084A2 (en) * | 2002-11-29 | 2004-06-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Ace-inhibitors having antioxidant and nitricoxid-donor activity |
| US20060223888A1 (en) * | 2002-12-16 | 2006-10-05 | Abbott Frank S | Valproic acid analogues and pharmaceutical composition thereof |
| EP1543831A1 (en) * | 2003-12-18 | 2005-06-22 | Pfizer GmbH Arzneimittelwerk Gödecke | Pregabalin composition |
| WO2006012603A2 (en) * | 2004-07-22 | 2006-02-02 | Nps Pharmaceuticals, Inc. | Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases |
| EP1928807A4 (en) * | 2005-09-02 | 2011-05-04 | Picobella Llc | ONCOGENIC REGULATORS RNA FOR DIAGNOSIS AND THERAPY |
| US7459280B2 (en) * | 2006-02-27 | 2008-12-02 | Picobella, Llc | Methods for diagnosing and treating kidney cancer |
| US20080267977A1 (en) * | 2007-04-26 | 2008-10-30 | Friedrich-Alexander University Of Erlangen-Nuremberg | Combined immunological agent and sensitizing agent for the treatment of cancer |
| EP2882427A2 (en) * | 2012-05-08 | 2015-06-17 | Cellixbio Private Limited | Compositions and methods for the treatment of neurological disorders |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2442M (fr) | 1962-10-17 | 1964-04-06 | Henry Eugene | L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central. |
| US3701729A (en) | 1970-06-01 | 1972-10-31 | Tenneco Chem | Oil-soluble mixed copper soap products |
| US3847956A (en) | 1973-04-06 | 1974-11-12 | Us Agriculture | 2-hydroperoxycarboxylic acids and their preparation |
| US3932285A (en) | 1973-10-03 | 1976-01-13 | Tenneco Chemicals, Inc. | Chromium salt compositions and a process for their production |
| US4025649A (en) | 1974-08-19 | 1977-05-24 | Labaz | Acetic acid derivatives having pharmacological activity and compositions containing the same |
| US4129599A (en) | 1975-04-28 | 1978-12-12 | The Board Of Trustees Of Leland Stanford Jr. University | A-Norsteroids |
| JPS5680116A (en) | 1979-12-05 | 1981-07-01 | Sanyo Electric Co Ltd | Manufacture of substrate for magnetic bubble |
| JPH0233704B2 (ja) | 1982-10-07 | 1990-07-30 | Takeda Chemical Industries Ltd | Chikanbinirukarubonsanjudotai |
| FR2599737B1 (fr) | 1986-06-10 | 1989-05-19 | Sanofi Sa | Procede pour la fixation de groupes alkyles, alkenyles, cycloalkyles ou aralkyles sur une chaine carbonee portant un groupement fonctionnel |
| JPH01135740A (ja) | 1987-11-24 | 1989-05-29 | Nippon Mining Co Ltd | 光学活性を有する2―アルキル―1―アルカン酸の製造方法 |
| US5021398A (en) | 1989-10-26 | 1991-06-04 | Amp Incorporated | Method of forming patterned oxide superconducting films |
| US5102913A (en) * | 1991-07-01 | 1992-04-07 | Halikas James A | Treatment for cocaine use employing valproic acid |
| DE4231085A1 (de) | 1992-09-12 | 1994-03-17 | Desitin Arzneimittel Gmbh | VPA-analoge Antiepileptika |
| EP0661993B1 (en) | 1992-09-16 | 1997-05-07 | Genentech, Inc. | Protection against liver damage by hgf |
| WO1994012608A1 (en) | 1992-11-30 | 1994-06-09 | The Procter & Gamble Company | High sudsing detergent compositions with specially selected soaps |
| JP3304459B2 (ja) | 1992-12-18 | 2002-07-22 | 松下電器産業株式会社 | 電解コンデンサ駆動用電解液およびそれを用いた電解コンデンサ |
| TW248552B (no) | 1993-06-01 | 1995-06-01 | Onoda Yakuhin Kogyo Kk | |
| US5503830A (en) | 1993-09-10 | 1996-04-02 | Petrovax, L.L.C. | Compounds having immunostimulating activity and methods of use thereof |
| WO1995033044A1 (en) | 1994-05-27 | 1995-12-07 | The Procter & Gamble Company | Liquid laundry detergent compositions comprising specially selected soaps |
| US5681854A (en) | 1995-11-22 | 1997-10-28 | Alcon Laboratories, Inc. | Use of aliphatic carboxylic acid derivatives in ophthalmic disorders |
| IT1283489B1 (it) | 1996-07-23 | 1998-04-21 | Chiesi Farma Spa | Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico |
-
1999
- 1999-06-22 IL IL14041599A patent/IL140415A0/xx unknown
- 1999-06-22 CZ CZ20004833A patent/CZ20004833A3/cs unknown
- 1999-06-22 CN CN99808955A patent/CN1310622A/zh active Pending
- 1999-06-22 US US09/337,986 patent/US6268396B1/en not_active Expired - Fee Related
- 1999-06-22 PL PL99345364A patent/PL345364A1/xx not_active Application Discontinuation
- 1999-06-22 KR KR1020007014630A patent/KR20010071572A/ko not_active Withdrawn
- 1999-06-22 SK SK1999-2000A patent/SK19992000A3/sk unknown
- 1999-06-22 MX MXPA00012808A patent/MXPA00012808A/es unknown
- 1999-06-22 WO PCT/US1999/014081 patent/WO1999066920A1/en not_active Ceased
- 1999-06-22 JP JP2000555606A patent/JP2002518442A/ja active Pending
- 1999-06-22 EP EP99930555A patent/EP1089725A1/en not_active Withdrawn
- 1999-06-22 AU AU47071/99A patent/AU752192B2/en not_active Ceased
- 1999-06-22 HU HU0102456A patent/HUP0102456A3/hu unknown
- 1999-06-22 TR TR2000/03800T patent/TR200003800T2/xx unknown
- 1999-06-22 CA CA002335641A patent/CA2335641A1/en not_active Abandoned
- 1999-06-22 BR BR9911421-6A patent/BR9911421A/pt not_active IP Right Cessation
- 1999-06-27 TR TR2001/03249T patent/TR200103249T2/xx unknown
- 1999-06-28 AU AU52071/99A patent/AU5207199A/en not_active Abandoned
-
2000
- 2000-12-19 ZA ZA200007652A patent/ZA200007652B/en unknown
- 2000-12-20 NO NO20006506A patent/NO20006506L/no not_active Application Discontinuation
-
2001
- 2001-01-17 BG BG105163A patent/BG63744B1/bg unknown
- 2001-04-23 US US09/840,376 patent/US6458840B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1089725A1 (en) | 2001-04-11 |
| KR20010071572A (ko) | 2001-07-28 |
| HUP0102456A3 (en) | 2003-07-28 |
| CN1310622A (zh) | 2001-08-29 |
| AU5207199A (en) | 2000-01-24 |
| CZ20004833A3 (cs) | 2002-01-16 |
| AU752192B2 (en) | 2002-09-12 |
| IL140415A0 (en) | 2002-02-10 |
| BG105163A (bg) | 2002-03-29 |
| CA2335641A1 (en) | 1999-12-29 |
| US20010031789A1 (en) | 2001-10-18 |
| BR9911421A (pt) | 2001-03-27 |
| JP2002518442A (ja) | 2002-06-25 |
| SK19992000A3 (sk) | 2001-08-06 |
| TR200003800T2 (tr) | 2001-06-21 |
| US6268396B1 (en) | 2001-07-31 |
| US6458840B2 (en) | 2002-10-01 |
| WO1999066920A1 (en) | 1999-12-29 |
| TR200103249T2 (tr) | 2002-05-21 |
| ZA200007652B (en) | 2002-03-19 |
| AU4707199A (en) | 2000-01-10 |
| MXPA00012808A (es) | 2002-04-24 |
| NO20006506D0 (no) | 2000-12-20 |
| PL345364A1 (en) | 2001-12-17 |
| HUP0102456A2 (hu) | 2001-10-28 |
| BG63744B1 (bg) | 2002-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |