NO20006506L - Anvendelse av valproinsyreanalog for behandlingen og forebyggelsen av migrene og affektive sykdommer - Google Patents

Anvendelse av valproinsyreanalog for behandlingen og forebyggelsen av migrene og affektive sykdommer

Info

Publication number
NO20006506L
NO20006506L NO20006506A NO20006506A NO20006506L NO 20006506 L NO20006506 L NO 20006506L NO 20006506 A NO20006506 A NO 20006506A NO 20006506 A NO20006506 A NO 20006506A NO 20006506 L NO20006506 L NO 20006506L
Authority
NO
Norway
Prior art keywords
migraine
valproic acid
affective
prevention
acid analog
Prior art date
Application number
NO20006506A
Other languages
English (en)
Other versions
NO20006506D0 (no
Inventor
Heinz Nau
Emer Leahy
Alan O'connell
Original Assignee
American Biogenetic Sciences
Heinz Nau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Biogenetic Sciences, Heinz Nau filed Critical American Biogenetic Sciences
Publication of NO20006506D0 publication Critical patent/NO20006506D0/no
Publication of NO20006506L publication Critical patent/NO20006506L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Foreliggende oppfinnelse omhandler en fremgangsmåte for behandling og forebygging av migrene og affektive sykdom ved administrering av en terapeutisk effektiv mengde av valproinsyre-analogen 2-n-propyl-4-heksynsyre. For- bindelsen 2-n-propyl-4-heksynsyre er et effektivt anti- migrene og anti-affektivt sykdomslegemiddel med svært reduserte ugunstige virkninger inkludert nevrotoksisitet og teratogent potensiale sammenlignet med valproinsyre. Fore- liggende oppfinnelse gir derfor en forbedret fremgangsmåte for å behandle og forebygge migrene og affektiv sykdom.
NO20006506A 1998-06-22 2000-12-20 Anvendelse av valproinsyreanalog for behandlingen og forebyggelsen av migrene og affektive sykdommer NO20006506L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9028198P 1998-06-22 1998-06-22
PCT/US1999/014081 WO1999066920A1 (en) 1998-06-22 1999-06-22 The use of valproic acid analog for the treatment and prevention of migraine and affective illness

Publications (2)

Publication Number Publication Date
NO20006506D0 NO20006506D0 (no) 2000-12-20
NO20006506L true NO20006506L (no) 2001-02-21

Family

ID=22222101

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006506A NO20006506L (no) 1998-06-22 2000-12-20 Anvendelse av valproinsyreanalog for behandlingen og forebyggelsen av migrene og affektive sykdommer

Country Status (19)

Country Link
US (2) US6268396B1 (no)
EP (1) EP1089725A1 (no)
JP (1) JP2002518442A (no)
KR (1) KR20010071572A (no)
CN (1) CN1310622A (no)
AU (2) AU752192B2 (no)
BG (1) BG63744B1 (no)
BR (1) BR9911421A (no)
CA (1) CA2335641A1 (no)
CZ (1) CZ20004833A3 (no)
HU (1) HUP0102456A3 (no)
IL (1) IL140415A0 (no)
MX (1) MXPA00012808A (no)
NO (1) NO20006506L (no)
PL (1) PL345364A1 (no)
SK (1) SK19992000A3 (no)
TR (2) TR200003800T2 (no)
WO (1) WO1999066920A1 (no)
ZA (1) ZA200007652B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6104802A (en) 1997-02-10 2000-08-15 Genesys Telecommunications Laboratories, Inc. In-band signaling for routing
DK1181012T3 (da) * 1999-05-04 2005-01-24 Keith R Edwards Intravenöst valproat til akut behandling af migrænehovedpine
PL365588A1 (en) 2000-07-21 2005-01-10 Teva Pharmaceutical Industries, Ltd. Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder
DK1311256T3 (da) * 2000-08-17 2005-11-28 Teva Pharma Anvendelse af derivater af valproinsyreamider og 2-valproinsyreamider til behandling eller forebyggelse af smerter og/eller hovedpinelidelser
US20020103110A1 (en) * 2001-01-26 2002-08-01 Spitzer A. Robert System and method for rectal administration of medication for treatment of migraines
US7968569B2 (en) * 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
EP1562975A2 (en) * 2002-10-25 2005-08-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
US20060166894A1 (en) * 2002-11-29 2006-07-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ace-inhibitors having antioxidant and no-donor activity
US20060223888A1 (en) * 2002-12-16 2006-10-05 Abbott Frank S Valproic acid analogues and pharmaceutical composition thereof
EP1543831A1 (en) * 2003-12-18 2005-06-22 Pfizer GmbH Arzneimittelwerk Gödecke Pregabalin composition
WO2006012603A2 (en) * 2004-07-22 2006-02-02 Nps Pharmaceuticals, Inc. Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
WO2007028030A2 (en) * 2005-09-02 2007-03-08 Picobella, Llc Oncogenic regulatory rnas for diagnostics and therapeutics
US7459280B2 (en) * 2006-02-27 2008-12-02 Picobella, Llc Methods for diagnosing and treating kidney cancer
US20080267977A1 (en) * 2007-04-26 2008-10-30 Friedrich-Alexander University Of Erlangen-Nuremberg Combined immunological agent and sensitizing agent for the treatment of cancer
JP2015533114A (ja) * 2012-05-08 2015-11-19 セリックスビオ プライヴェート リミテッド 神経疾患の治療のための組成物及び方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2442M (fr) 1962-10-17 1964-04-06 Henry Eugene L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.
US3701729A (en) 1970-06-01 1972-10-31 Tenneco Chem Oil-soluble mixed copper soap products
US3847956A (en) 1973-04-06 1974-11-12 Us Agriculture 2-hydroperoxycarboxylic acids and their preparation
US3932285A (en) 1973-10-03 1976-01-13 Tenneco Chemicals, Inc. Chromium salt compositions and a process for their production
US4025649A (en) 1974-08-19 1977-05-24 Labaz Acetic acid derivatives having pharmacological activity and compositions containing the same
US4129599A (en) 1975-04-28 1978-12-12 The Board Of Trustees Of Leland Stanford Jr. University A-Norsteroids
JPS5680116A (en) 1979-12-05 1981-07-01 Sanyo Electric Co Ltd Manufacture of substrate for magnetic bubble
JPH0233704B2 (ja) 1982-10-07 1990-07-30 Takeda Chemical Industries Ltd Chikanbinirukarubonsanjudotai
FR2599737B1 (fr) 1986-06-10 1989-05-19 Sanofi Sa Procede pour la fixation de groupes alkyles, alkenyles, cycloalkyles ou aralkyles sur une chaine carbonee portant un groupement fonctionnel
JPH01135740A (ja) 1987-11-24 1989-05-29 Nippon Mining Co Ltd 光学活性を有する２―アルキル―１―アルカン酸の製造方法
US5021398A (en) 1989-10-26 1991-06-04 Amp Incorporated Method of forming patterned oxide superconducting films
US5102913A (en) * 1991-07-01 1992-04-07 Halikas James A Treatment for cocaine use employing valproic acid
DE4231085A1 (de) * 1992-09-12 1994-03-17 Desitin Arzneimittel Gmbh VPA-analoge Antiepileptika
CA2144081C (en) 1992-09-16 2004-11-30 Filip Roos Protection against liver damage by hgf
AU5678194A (en) 1992-11-30 1994-06-22 Procter & Gamble Company, The High sudsing detergent compositions with specially selected soaps
JP3304459B2 (ja) 1992-12-18 2002-07-22 松下電器産業株式会社 電解コンデンサ駆動用電解液およびそれを用いた電解コンデンサ
EP0632008B1 (en) 1993-06-01 1998-02-04 Ono Pharmaceutical Co., Ltd. Pentanoic acid derivatives
US5503830A (en) 1993-09-10 1996-04-02 Petrovax, L.L.C. Compounds having immunostimulating activity and methods of use thereof
WO1995033044A1 (en) 1994-05-27 1995-12-07 The Procter & Gamble Company Liquid laundry detergent compositions comprising specially selected soaps
US5681854A (en) 1995-11-22 1997-10-28 Alcon Laboratories, Inc. Use of aliphatic carboxylic acid derivatives in ophthalmic disorders
IT1283489B1 (it) 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico

Also Published As

Publication number Publication date
BR9911421A (pt) 2001-03-27
HUP0102456A2 (hu) 2001-10-28
MXPA00012808A (es) 2002-04-24
CN1310622A (zh) 2001-08-29
US20010031789A1 (en) 2001-10-18
BG63744B1 (bg) 2002-11-29
NO20006506D0 (no) 2000-12-20
ZA200007652B (en) 2002-03-19
CA2335641A1 (en) 1999-12-29
IL140415A0 (en) 2002-02-10
TR200103249T2 (tr) 2002-05-21
SK19992000A3 (sk) 2001-08-06
PL345364A1 (en) 2001-12-17
AU5207199A (en) 2000-01-24
CZ20004833A3 (cs) 2002-01-16
EP1089725A1 (en) 2001-04-11
AU4707199A (en) 2000-01-10
US6458840B2 (en) 2002-10-01
HUP0102456A3 (en) 2003-07-28
AU752192B2 (en) 2002-09-12
BG105163A (bg) 2002-03-29
US6268396B1 (en) 2001-07-31
KR20010071572A (ko) 2001-07-28
TR200003800T2 (tr) 2001-06-21
JP2002518442A (ja) 2002-06-25
WO1999066920A1 (en) 1999-12-29

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