BG105236A - New carboxylic acid derivatives carrying keto side-chains, their production and use as endothelin-receptor antagonists - Google Patents

New carboxylic acid derivatives carrying keto side-chains, their production and use as endothelin-receptor antagonists

Info

Publication number: BG105236A
Authority: BG; Bulgaria
Prior art keywords: endothelin; production; carboxylic acid; acid derivatives; receptor antagonists
Prior art date: 1998-08-10

Application number

BG105236A

Other languages

Bulgarian (bg)

English (en)

Inventor

Wilhelm Amberg

Rolf Jansen

Georg Kettschau

Stefan Hergenroeder

Manfred Raschack

Liliane Unger

Original Assignee

Abbott Gmbh & Co. Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-10

Filing date

2001-02-09

Publication date

2001-12-29

2001-02-09 Application filed by Abbott Gmbh & Co. Kg filed Critical Abbott Gmbh & Co. Kg

2001-12-29 Publication of BG105236A publication Critical patent/BG105236A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Plural Heterocyclic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BG105236A 1998-08-10 2001-02-09 New carboxylic acid derivatives carrying keto side-chains, their production and use as endothelin-receptor antagonists BG105236A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19836044A DE19836044A1 (de)	1998-08-10	1998-08-10	Neue Carbonsäurederivate, die Ketoseitenketten tragen, ihre Herstellung und Verwendung als Endothelin-Rezeptorantagonisten
PCT/EP1999/005728 WO2000009489A1 (de)	1998-08-10	1999-08-07	Neue carbonsäurederivate, die ketoseitenketten tragen, ihre herstellung und verwendung als endothelin-rezeptorantagonisten

Publications (1)

Publication Number	Publication Date
BG105236A true BG105236A (en)	2001-12-29

Family

ID=7876981

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG105236A BG105236A (en)	1998-08-10	2001-02-09	New carboxylic acid derivatives carrying keto side-chains, their production and use as endothelin-receptor antagonists

Country Status (22)

Country	Link
EP (1)	EP1104410A1 (id)
JP (1)	JP2002522531A (id)
KR (1)	KR20010072378A (id)
CN (1)	CN1323298A (id)
AR (1)	AR020147A1 (id)
AU (1)	AU5374199A (id)
BG (1)	BG105236A (id)
BR (1)	BR9912889A (id)
CA (1)	CA2340167A1 (id)
CO (1)	CO5261504A1 (id)
DE (1)	DE19836044A1 (id)
HK (1)	HK1042086A1 (id)
HR (1)	HRP20010164A2 (id)
HU (1)	HUP0104007A3 (id)
ID (1)	ID27965A (id)
IL (1)	IL140915A0 (id)
NO (1)	NO20010622L (id)
PL (1)	PL345998A1 (id)
SK (1)	SK832001A3 (id)
TR (1)	TR200100427T2 (id)
WO (1)	WO2000009489A1 (id)
ZA (1)	ZA200101975B (id)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19924892A1 (de) *	1999-06-01	2000-12-07	Basf Ag	Neue Carbonsäurederivate mit arylsubstituierten Stickstoffheterocyclen, ihre Herstellung und Verwendung als Endothelin Rezeptorantagonisten

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19636046A1 (de) *	1996-09-05	1998-03-12	Basf Ag	Neue Carbonsäurederivate, ihre Herstellung und Verwendung als gemischte ET¶A¶/ET¶B¶-Rezeptorantagonisten

1998
- 1998-08-10 DE DE19836044A patent/DE19836044A1/de not_active Withdrawn
1999
- 1999-08-07 AU AU53741/99A patent/AU5374199A/en not_active Abandoned
- 1999-08-07 HU HU0104007A patent/HUP0104007A3/hu unknown
- 1999-08-07 CN CN99811981A patent/CN1323298A/zh active Pending
- 1999-08-07 IL IL14091599A patent/IL140915A0/xx unknown
- 1999-08-07 HR HR20010164A patent/HRP20010164A2/hr not_active Application Discontinuation
- 1999-08-07 BR BR9912889-6A patent/BR9912889A/pt not_active Application Discontinuation
- 1999-08-07 PL PL99345998A patent/PL345998A1/xx not_active Application Discontinuation
- 1999-08-07 KR KR1020017001731A patent/KR20010072378A/ko not_active Withdrawn
- 1999-08-07 CA CA002340167A patent/CA2340167A1/en not_active Abandoned
- 1999-08-07 JP JP2000564942A patent/JP2002522531A/ja active Pending
- 1999-08-07 SK SK83-2001A patent/SK832001A3/sk unknown
- 1999-08-07 HK HK02103679.0A patent/HK1042086A1/zh unknown
- 1999-08-07 TR TR2001/00427T patent/TR200100427T2/xx unknown
- 1999-08-07 ID IDW20010326A patent/ID27965A/id unknown
- 1999-08-07 WO PCT/EP1999/005728 patent/WO2000009489A1/de not_active Ceased
- 1999-08-07 EP EP99939457A patent/EP1104410A1/de not_active Withdrawn
- 1999-08-10 AR ARP990103985A patent/AR020147A1/es not_active Application Discontinuation
- 1999-08-10 CO CO99050715A patent/CO5261504A1/es not_active Application Discontinuation
2001
- 2001-02-06 NO NO20010622A patent/NO20010622L/no not_active Application Discontinuation
- 2001-02-09 BG BG105236A patent/BG105236A/xx unknown
- 2001-03-09 ZA ZA200101975A patent/ZA200101975B/en unknown

Also Published As

Publication number	Publication date
AU5374199A (en)	2000-03-06
DE19836044A1 (de)	2000-02-17
NO20010622D0 (no)	2001-02-06
ID27965A (id)	2001-05-03
CO5261504A1 (es)	2003-03-31
CA2340167A1 (en)	2000-02-24
AR020147A1 (es)	2002-04-10
HUP0104007A2 (hu)	2002-05-29
JP2002522531A (ja)	2002-07-23
CN1323298A (zh)	2001-11-21
SK832001A3 (en)	2001-11-06
NO20010622L (no)	2001-02-06
PL345998A1 (en)	2002-01-14
KR20010072378A (ko)	2001-07-31
WO2000009489A1 (de)	2000-02-24
HK1042086A1 (zh)	2002-08-02
EP1104410A1 (de)	2001-06-06
BR9912889A (pt)	2001-05-08
TR200100427T2 (tr)	2001-07-23
HUP0104007A3 (en)	2002-12-28
IL140915A0 (en)	2002-02-10
ZA200101975B (en)	2002-03-11
HRP20010164A2 (en)	2002-04-30

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