BG105310A - Process for the preparation of a non-crystalline anhydrate from paroxetine hydrochloride - Google Patents

Process for the preparation of a non-crystalline anhydrate from paroxetine hydrochloride

Info

Publication number: BG105310A
Authority: BG; Bulgaria
Prior art keywords: paroxetine hydrochloride; preparation; crystalline anhydrate; propan; solvate
Prior art date: 1998-08-07

Application number

BG105310A

Other languages

Bulgarian (bg)

English (en)

Inventor

Victor JACEWICZ

Neal Ward

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-07

Filing date

2001-03-06

Publication date

2001-12-29

1998-08-07 Priority claimed from GBGB9817196.0A external-priority patent/GB9817196D0/en

1998-12-29 Priority claimed from GBGB9828777.4A external-priority patent/GB9828777D0/en

2001-03-06 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2001-12-29 Publication of BG105310A publication Critical patent/BG105310A/xx

Links

AHOUBRCZNHFOSL-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine Chemical compound C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title abstract 6
229960005183 paroxetine hydrochloride Drugs 0.000 title abstract 3
239000012453 solvate Substances 0.000 abstract 3
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
238000010438 heat treatment Methods 0.000 abstract 2
230000007423 decrease Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

BG105310A 1998-08-07 2001-03-06 Process for the preparation of a non-crystalline anhydrate from paroxetine hydrochloride BG105310A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9817196.0A GB9817196D0 (en)	1998-08-07	1998-08-07	Novel process
GBGB9828777.4A GB9828777D0 (en)	1998-12-29	1998-12-29	Novel compounds
PCT/GB1999/002592 WO2000008017A1 (en)	1998-08-07	1999-08-06	Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride

Publications (1)

Publication Number	Publication Date
BG105310A true BG105310A (en)	2001-12-29

Family

ID=26314179

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG105310A BG105310A (en)	1998-08-07	2001-03-06	Process for the preparation of a non-crystalline anhydrate from paroxetine hydrochloride

Country Status (23)

Country	Link
EP (2)	EP1100796B1 (id)
JP (1)	JP2002522434A (id)
KR (1)	KR20010072323A (id)
CN (1)	CN1321155A (id)
AP (2)	AP2001002072A0 (id)
AT (1)	ATE239016T1 (id)
AU (1)	AU5428999A (id)
BG (1)	BG105310A (id)
BR (1)	BR9912858A (id)
CA (1)	CA2339857A1 (id)
DE (1)	DE69907467T2 (id)
DK (1)	DK1100796T3 (id)
EA (1)	EA200100221A1 (id)
ES (1)	ES2198940T3 (id)
HU (1)	HUP0105466A3 (id)
ID (1)	ID27914A (id)
IL (1)	IL141286A0 (id)
NO (1)	NO20010629L (id)
PL (1)	PL345885A1 (id)
PT (1)	PT1100796E (id)
SK (1)	SK1972001A3 (id)
TR (1)	TR200100444T2 (id)
WO (1)	WO2000008017A1 (id)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1394160A1 (en) *	1996-06-13	2004-03-03	SUMIKA FINE CHEMICALS Co., Ltd.	Process for preparing crystalline paroxetin hydrochloride
JP3796351B2 (ja)	1998-04-13	2006-07-12	住友化学株式会社	パロキセチン塩酸塩無水和物の乾燥方法
GB9923446D0 (en) *	1999-10-04	1999-12-08	Smithkline Beecham Plc	Novel process
JP2005538031A (ja) *	2000-11-17	2005-12-15	イーライ・リリー・アンド・カンパニー	ラクタム化合物
EP1552833B1 (en) *	2002-10-16	2016-12-28	Takeda Pharmaceutical Company Limited	Process for producing an amorphous optically active isomer of lansoprazole

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1422263A (en) *	1973-01-30	1976-01-21	Ferrosan As	4-phenyl-piperidine compounds
EP0223403B1 (en) *	1985-10-25	1993-08-04	Beecham Group Plc	Piperidine derivative, its preparation, and its use as medicament
AR001982A1 (es) *	1995-02-06	1998-01-07	Smithkline Beecham Plc	Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion
JP2001508460A (ja) *	1997-01-15	2001-06-26	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	パロキセチン組成物
JP3796351B2 (ja) *	1998-04-13	2006-07-12	住友化学株式会社	パロキセチン塩酸塩無水和物の乾燥方法

1999
- 1999-08-06 WO PCT/GB1999/002592 patent/WO2000008017A1/en not_active Ceased
- 1999-08-06 AP AP2001002072A patent/AP2001002072A0/xx unknown
- 1999-08-06 PL PL99345885A patent/PL345885A1/xx not_active Application Discontinuation
- 1999-08-06 IL IL14128699A patent/IL141286A0/xx unknown
- 1999-08-06 JP JP2000563650A patent/JP2002522434A/ja active Pending
- 1999-08-06 DE DE69907467T patent/DE69907467T2/de not_active Expired - Fee Related
- 1999-08-06 AU AU54289/99A patent/AU5428999A/en not_active Abandoned
- 1999-08-06 HU HU0105466A patent/HUP0105466A3/hu unknown
- 1999-08-06 EP EP99940290A patent/EP1100796B1/en not_active Expired - Lifetime
- 1999-08-06 ID IDW20010296A patent/ID27914A/id unknown
- 1999-08-06 CN CN99811643A patent/CN1321155A/zh active Pending
- 1999-08-06 ES ES99940290T patent/ES2198940T3/es not_active Expired - Lifetime
- 1999-08-06 EA EA200100221A patent/EA200100221A1/ru unknown
- 1999-08-06 BR BR9912858-6A patent/BR9912858A/pt not_active Application Discontinuation
- 1999-08-06 KR KR1020017001635A patent/KR20010072323A/ko not_active Withdrawn
- 1999-08-06 AP APAP/P/2001/002072A patent/AP0102072A0/en unknown
- 1999-08-06 DK DK99940290T patent/DK1100796T3/da active
- 1999-08-06 TR TR2001/00444T patent/TR200100444T2/xx unknown
- 1999-08-06 AT AT99940290T patent/ATE239016T1/de not_active IP Right Cessation
- 1999-08-06 EP EP02080022A patent/EP1321465A3/en not_active Withdrawn
- 1999-08-06 PT PT99940290T patent/PT1100796E/pt unknown
- 1999-08-06 SK SK197-2001A patent/SK1972001A3/sk unknown
- 1999-08-06 CA CA002339857A patent/CA2339857A1/en not_active Abandoned
2001
- 2001-02-06 NO NO20010629A patent/NO20010629L/no not_active Application Discontinuation
- 2001-03-06 BG BG105310A patent/BG105310A/xx unknown

Also Published As

Publication number	Publication date
AP2001002072A0 (en)	2001-03-31
TR200100444T2 (tr)	2001-07-23
EP1321465A3 (en)	2003-09-03
JP2002522434A (ja)	2002-07-23
ID27914A (id)	2001-05-03
AU5428999A (en)	2000-02-28
WO2000008017A1 (en)	2000-02-17
EA200100221A1 (ru)	2001-08-27
EP1321465A2 (en)	2003-06-25
EP1100796B1 (en)	2003-05-02
PL345885A1 (en)	2002-01-14
AP0102072A0 (en)	2001-02-06
DE69907467T2 (de)	2004-03-11
SK1972001A3 (en)	2001-08-06
NO20010629L (no)	2001-03-20
ATE239016T1 (de)	2003-05-15
CA2339857A1 (en)	2000-02-17
HK1038230A1 (en)	2002-03-08
CN1321155A (zh)	2001-11-07
PT1100796E (pt)	2003-09-30
HUP0105466A2 (hu)	2002-05-29
NO20010629D0 (no)	2001-02-06
ES2198940T3 (es)	2004-02-01
DK1100796T3 (da)	2003-08-25
EP1100796A1 (en)	2001-05-23
KR20010072323A (ko)	2001-07-31
HUP0105466A3 (en)	2002-11-28
BR9912858A (pt)	2001-11-20
IL141286A0 (en)	2002-03-10
DE69907467D1 (de)	2003-06-05

Publication	Publication Date	Title
PL319384A1 (en)	1997-08-04	Steroic compositions from soap mass
MY119800A (en)	2005-07-29	Pyridine derivatives
GR1002466B (el)	1996-11-06	Νεες ενωσεις.
CZ258896A3 (en)	1997-03-12	Morpholine derivatives, process of their preparation and pharmaceutical compositions containing thereof
MY124151A (en)	2006-06-30	Epothilone derivatives
HUP0101511A3 (en)	2002-12-28	1-[(1-substituted-4-piperidinyl)methyl]-4-piperidine derivatives, process for producing the same, medicinal compositions containing the same and intermediates of these compounds
DK0923554T3 (da)	2002-04-29	N-Benzylpiperidin- og tetrahydropyridinderivater
IL127929A0 (en)	1999-11-30	Use of novel glass compositions in preparing dental glass pillars and support pillars and method for producing the glass pillars
AP0102072A0 (en)	2001-02-06	Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride.
MY125975A (en)	2006-09-29	Crystalline form vii of cabergoline
MY120550A (en)	2005-11-30	Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, processes for preparing them and their use as pharmaceutical compositions.
ZA962059B (en)	1996-12-31	Control of expansion in concrete due to alkali silica reaction
BG105204A (en)	2001-11-30	Salts of paroxetine
NZ505200A (en)	2002-09-27	Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists
PL344994A1 (en)	2001-11-19	Derivatives of 3-(2-oxo-[1,3']bipyrrolidinyl-3-ylidenemethyl)-cephems
EG19390A (en)	1995-01-31	Process for preparing compositions useful as contraceptives males
GB9806409D0 (en)	1998-05-20	Processes for preparing intermediates
BG105247A (en)	2001-11-30	N-substituted azabicycloheptane derivatives, production and use thereof
MXPA02006965A (es)	2004-09-06	Solvato de etanol de (-) -cis-2 -(2-clorofenil) -5, 7-dihidroxi -8[4r-(3s -hidroxi -1-metil] piperidinil] -4h-1 -benzopiran-4 -ona.
ATE262516T1 (de)	2004-04-15	Kristallines (-)-3r,4r-trans-7-methoxy-2,2-
NO20012028L (no)	2001-04-25	Fremgangsmåte for fremstilling av 4-((2',5'-diamino-6'- halogenpyrimidin-4'-yl)amino)-cyclopent-2-enyl-metanoler
PL318280A1 (en)	1997-06-09	Novel polymorphous modifications of lesopitrone dihydrochloride and theirhydrogenated forms, methods of obtaining them and compositions containing them
AU2000246281A1 (en)	2001-11-20	Piperidine compounds and process for providing such
GB9615882D0 (en)	1996-09-11	Composition for the removal of lipstick marks from glassware