BG106221A - Назални фармацевтични препарати съдържащи морфин и методи на приложението им - Google Patents

Назални фармацевтични препарати съдържащи морфин и методи на приложението им

Info

Publication number: BG106221A
Authority: BG; Bulgaria
Prior art keywords: morphin; methods; application; pharmaceutical preparations; preparations containing
Prior art date: 1999-06-16

Application number

BG106221A

Other languages

Bulgarian (bg)

English (en)

Inventor

Raja ACHARI

Charanjit Behl

Jorge DEMEIRELES

Ramneik Dua

Vincent Romeo

Anthony SILENO

Original Assignee

Nastech Pharmaceutical Co., Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-16

Filing date

2001-12-14

Publication date

2002-08-30

2001-12-14 Application filed by Nastech Pharmaceutical Co., Inc. filed Critical Nastech Pharmaceutical Co., Inc.

2002-08-30 Publication of BG106221A publication Critical patent/BG106221A/xx

Links

BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 title abstract 8
229960005181 morphine Drugs 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
239000000825 pharmaceutical preparation Substances 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 3
241000124008 Mammalia Species 0.000 abstract 1
238000010521 absorption reaction Methods 0.000 abstract 1
230000003444 anaesthetic effect Effects 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Otolaryngology (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

BG106221A 1999-06-16 2001-12-14 Назални фармацевтични препарати съдържащи морфин и методи на приложението им BG106221A (bg)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US33453799A	1999-06-16	1999-06-16
PCT/US2000/014157 WO2000076506A1 (fr)	1999-06-16	2000-05-23	Formulations pharmaceutiques et procedes comprenant de la morphine s'administrant par voie intra-nasale

Publications (1)

Publication Number	Publication Date
BG106221A true BG106221A (bg)	2002-08-30

Family

ID=23307687

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG106221A BG106221A (bg)	1999-06-16	2001-12-14	Назални фармацевтични препарати съдържащи морфин и методи на приложението им

Country Status (30)

Country	Link
US (1)	US6677346B1 (fr)
EP (2)	EP1183027A4 (fr)
JP (1)	JP2003501467A (fr)
KR (1)	KR20020016831A (fr)
AU (1)	AU774175B2 (fr)
BG (1)	BG106221A (fr)
BR (1)	BR0012082A (fr)
CA (1)	CA2374877C (fr)
CZ (1)	CZ20014399A3 (fr)
DE (1)	DE10084709T1 (fr)
DK (1)	DK200101859A (fr)
EE (1)	EE200100677A (fr)
ES (1)	ES2197792B1 (fr)
FI (1)	FI20012462A7 (fr)
GB (1)	GB2367005A (fr)
HR (1)	HRP20010926A2 (fr)
HU (1)	HUP0201856A3 (fr)
IS (1)	IS6202A (fr)
LT (1)	LT4976B (fr)
LU (1)	LU90859B1 (fr)
LV (1)	LV12859B (fr)
MX (1)	MXPA01012879A (fr)
NO (1)	NO20015931L (fr)
NZ (1)	NZ515783A (fr)
PL (1)	PL352556A1 (fr)
SE (1)	SE0104203L (fr)
SI (1)	SI20850A (fr)
SK (1)	SK18172001A3 (fr)
TR (1)	TR200103613T2 (fr)
WO (1)	WO2000076506A1 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9924797D0 (en)	1999-10-20	1999-12-22	West Pharm Serv Drug Res Ltd	Compound
US20060083691A1 (en) *	2000-05-10	2006-04-20	Wermeling Daniel P	Intranasal opioid compositions, delivery devices and methods of using same
US20040115133A1 (en) *	2000-05-10	2004-06-17	Wermeling Daniel P.	Intranasal opioid compositions
US6572849B2 (en) *	2000-09-20	2003-06-03	Lee Shahinian, Jr.	Self-preserved antibacterial nasal, inhalable, and topical ophthalmic preparations and medications
EP1418862A4 (fr) *	2001-06-29	2010-06-09	Leon J Lewandowski	Therapie de sevrage individualisee en cas de dependance
GB0210264D0 (en) *	2002-05-03	2002-06-12	Arakis Ltd	The treatment of pain and migraine headache
US20040102476A1 (en) *	2002-11-25	2004-05-27	Chan Tai Wah	High concentration formulations of opioids and opioid derivatives
US20050175679A1 (en) *	2004-02-10	2005-08-11	Michael Moshman	Controlled release formulations
US9895444B2 (en)	2004-08-25	2018-02-20	Aegis Therapeutics, Llc	Compositions for drug administration
US20140162965A1 (en)	2004-08-25	2014-06-12	Aegis Therapeutics, Inc.	Compositions for oral drug administration
PL2486942T3 (pl)	2004-11-24	2019-05-31	Meda Pharmaceuticals Inc	Kompozycje zawierające azelastynę oraz sposoby ich stosowania
US9415034B2 (en) *	2005-01-05	2016-08-16	National Defense Medical Center	Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2B (UGT2B)
ES2277743B2 (es)	2005-06-02	2008-12-16	Universidade De Santiago De Compostela	Nanoparticulas que comprenden quitosano y ciclodextrina.
JP5276982B2 (ja)	2005-08-26	2013-08-28	ボードオブトラスティーズオブザレランドスタンフォードジュニアユニバーシティ	オキシトシンの投与による頭痛の処置のための方法
US20070212307A1 (en) *	2006-02-10	2007-09-13	Daniel Wermeling	Pharmaceutical Compositions Comprising an Opioid Receptor Antagonist and Methods of Using Same
US8226949B2 (en)	2006-06-23	2012-07-24	Aegis Therapeutics Llc	Stabilizing alkylglycoside compositions and methods thereof
AU2007338210B2 (en) *	2006-12-22	2013-01-31	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Gel useful for the delivery of ophthalmic drugs
GB2477545B (en) *	2010-02-05	2011-12-21	Special Products Ltd	A liquid morphine composition for buccal administration
HRP20180233T1 (hr)	2011-05-13	2018-06-01	Euro-Celtique S.A.	Intranazalni farmaceutski oblici doziranja koji sadrže nalokson
US20150231130A1 (en)	2012-07-26	2015-08-20	Wockhardt Limited	Pharmaceutical composition comprising diamorphine for intranasal administration
WO2015095389A1 (fr) *	2013-12-18	2015-06-25	Aegis Therapeutics, Llc	Compositions pour administration de médicaments
US11135155B2 (en)	2014-07-08	2021-10-05	Hikma Pharmaceuticals Usa Inc.	Liquid naloxone spray
PL3242676T3 (pl)	2015-01-07	2024-07-15	Tonix Pharma Limited	Preparaty oksytocyny zawierające magnez i sposoby ich stosowania
HRP20250215T1 (hr)	2016-04-12	2025-06-20	Tonix Pharma Limited	Formulacije oksitocina koje sadrže magnezij i postupci upotrebe
EP3528797A1 (fr) *	2016-10-21	2019-08-28	Somniferum Labs LLC	Compositions, méthodes et kits pour l'administration par inhalation sûre d'opioïdes ciblés pour le traitement de la douleur et de la dépendance
MA50394A (fr) *	2017-10-20	2021-04-28	Chiesi Farm Spa	Formulations pharmaceutiques comprenant un agoniste de récepteur d'opioïde en tant que substances actives, leurs procédés de fabrication et leurs utilisations thérapeutiques
JP6941224B2 (ja)	2018-02-06	2021-09-29	イージスセラピューティクス，エルエルシー	疾患の処置のための鼻腔内エピネフリン製剤及び方法
CN115804754A (zh) *	2022-12-16	2023-03-17	广州新济药业科技有限公司	吗啡鼻喷剂及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4464378A (en)	1981-04-28	1984-08-07	University Of Kentucky Research Foundation	Method of administering narcotic antagonists and analgesics and novel dosage forms containing same
US4464376A (en)	1982-07-22	1984-08-07	Richardson-Vicks, Inc.	Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
GB8514665D0 (en) *	1985-06-11	1985-07-10	Eroceltique Sa	Oral pharmaceutical composition
US5202128A (en)	1989-01-06	1993-04-13	F. H. Faulding & Co. Limited	Sustained release pharmaceutical composition
GB9202464D0 (en) *	1992-02-05	1992-03-18	Danbiosyst Uk	Composition for nasal administration
DE69434304T2 (de) *	1993-03-26	2005-12-29	Merkus, Franciscus Wilhelmus H.M.	Pharmazeutische Zusammensetzungen zur intranasalen Verabreichung von Dihydroergotamin
GB9426102D0 (en)	1994-12-23	1995-02-22	Merck Sharp & Dohme	Pharmacuetical compositions
CA2266898A1 (fr) *	1996-09-27	1998-04-02	Nastech Pharmaceutical Co., Inc.	Formulations intranasales pour favoriser le sommeil et leur procede d'utilisation

2000
- 2000-05-23 TR TR2001/03613T patent/TR200103613T2/xx unknown
- 2000-05-23 SK SK1817-2001A patent/SK18172001A3/sk unknown
- 2000-05-23 PL PL00352556A patent/PL352556A1/xx not_active Application Discontinuation
- 2000-05-23 KR KR1020017016009A patent/KR20020016831A/ko not_active Ceased
- 2000-05-23 NZ NZ515783A patent/NZ515783A/en unknown
- 2000-05-23 EE EEP200100677A patent/EE200100677A/xx unknown
- 2000-05-23 DE DE10084709T patent/DE10084709T1/de not_active Ceased
- 2000-05-23 SI SI200020030A patent/SI20850A/sl not_active IP Right Cessation
- 2000-05-23 BR BR0012082-0A patent/BR0012082A/pt not_active IP Right Cessation
- 2000-05-23 EP EP00936212A patent/EP1183027A4/fr not_active Withdrawn
- 2000-05-23 GB GB0128383A patent/GB2367005A/en not_active Withdrawn
- 2000-05-23 JP JP2001502839A patent/JP2003501467A/ja active Pending
- 2000-05-23 MX MXPA01012879A patent/MXPA01012879A/es unknown
- 2000-05-23 HR HR20010926A patent/HRP20010926A2/hr not_active Application Discontinuation
- 2000-05-23 EP EP04001252A patent/EP1419774A1/fr not_active Withdrawn
- 2000-05-23 CZ CZ20014399A patent/CZ20014399A3/cs unknown
- 2000-05-23 CA CA002374877A patent/CA2374877C/fr not_active Expired - Fee Related
- 2000-05-23 HU HU0201856A patent/HUP0201856A3/hu unknown
- 2000-05-23 WO PCT/US2000/014157 patent/WO2000076506A1/fr not_active Ceased
- 2000-05-23 ES ES200150086A patent/ES2197792B1/es not_active Expired - Lifetime
- 2000-05-23 FI FI20012462A patent/FI20012462A7/fi not_active IP Right Cessation
- 2000-05-23 AU AU51561/00A patent/AU774175B2/en not_active Ceased
- 2000-06-15 US US09/594,916 patent/US6677346B1/en not_active Expired - Fee Related
2001
- 2001-12-04 NO NO20015931A patent/NO20015931L/no not_active Application Discontinuation
- 2001-12-12 DK DK200101859A patent/DK200101859A/da not_active Application Discontinuation
- 2001-12-13 LT LT2001119A patent/LT4976B/lt not_active IP Right Cessation
- 2001-12-13 LU LU90859A patent/LU90859B1/en active
- 2001-12-14 SE SE0104203A patent/SE0104203L/ not_active Application Discontinuation
- 2001-12-14 BG BG106221A patent/BG106221A/xx unknown
- 2001-12-14 IS IS6202A patent/IS6202A/is unknown
2002
- 2002-01-18 LV LVP-01-169A patent/LV12859B/en unknown

Also Published As

Publication number	Publication date
NO20015931L (no)	2002-02-08
EE200100677A (et)	2003-02-17
US6677346B1 (en)	2004-01-13
CA2374877A1 (fr)	2000-12-21
MXPA01012879A (es)	2003-06-24
PL352556A1 (en)	2003-08-25
HUP0201856A3 (en)	2004-12-28
GB2367005A (en)	2002-03-27
LT4976B (lt)	2002-12-30
GB0128383D0 (en)	2002-01-16
AU5156100A (en)	2001-01-02
SE0104203D0 (sv)	2001-12-14
CZ20014399A3 (cs)	2002-06-12
EP1183027A1 (fr)	2002-03-06
DK200101859A (da)	2001-12-12
HUP0201856A1 (en)	2002-09-28
EP1419774A1 (fr)	2004-05-19
DE10084709T1 (de)	2002-09-26
SK18172001A3 (sk)	2002-07-02
WO2000076506A1 (fr)	2000-12-21
SI20850A (sl)	2002-10-31
LU90859B1 (en)	2002-01-24
LV12859B (en)	2002-12-20
IS6202A (is)	2001-12-14
NZ515783A (en)	2004-05-28
NO20015931D0 (no)	2001-12-04
ES2197792A1 (es)	2004-01-01
KR20020016831A (ko)	2002-03-06
LT2001119A (en)	2002-07-25
AU774175B2 (en)	2004-06-17
FI20012462L (fi)	2002-01-16
ES2197792B1 (es)	2005-05-01
JP2003501467A (ja)	2003-01-14
BR0012082A (pt)	2002-05-07
SE0104203L (sv)	2001-12-14
TR200103613T2 (tr)	2004-08-23
HRP20010926A2 (en)	2003-04-30
CA2374877C (fr)	2004-04-13
EP1183027A4 (fr)	2003-02-05
FI20012462A7 (fi)	2002-01-16

Publication	Publication Date	Title
GB2367005A (en)	2002-03-27	Pharmaceutical formulations and methods comprising intranasal morphine
WO2000021515A3 (fr)	2000-09-28	Codeine intra-nasale permettant d'eliminer rapidement la toux et de soulager rapidement la douleur
NO20040968L (no)	2004-05-05	Opioidagonistpreparater med frigjorbar og sekvestrert antagonist
DE69629591D1 (de)	2003-09-25	Formulierung zur intranasalen verabreichung
BG106095A (bg)	2002-06-28	Нови лекарствени състави на базата на антихолинергично активни съединения и бета-миметици
ATE292982T1 (de)	2005-04-15	Analgesiche synergie durch gleichzeitige verabreichung von subanalgesichen doseneines mu- opioidanagonisten und eines kappa - 2- opioidanagonisten
WO2002042462A3 (fr)	2003-06-19	Agents therapeutiques et methodes d'utilisation de ces agents therapeutiques pour traiter une maladie amyloidogenique
SE0102276D0 (sv)	2001-06-25	Device and method for the administration of a medicament
EP1355564A4 (fr)	2007-06-06	Methode et dispositif d'administration de medicament et/ou de placebo
DK1039900T3 (da)	2004-10-04	Farmaceutisk præparat indeholdende sibutramin og orlistat
SE0102440D0 (sv)	2001-07-05	New compound
DE60133654D1 (de)	2008-05-29	Arzneimittel enthaltend analgetische peptide
EP0799618A3 (fr)	1997-11-12	Utilisation d'antagonistes de l'adrénorécepteur alpha 1 dans la fabrication d'unmédicament pur la prévention et au traitment du cancer
BR0011880A (pt)	2002-03-19	Método para o tratamento de condições co-mórbidas associadas com obesidade, composto, produto, uso de um composto, e, composição farmacêutica
DK1530459T3 (da)	2010-07-19	Oral farmaceutisk sammensætning til bløde kapsler indeholdende vinorelbin samt fremgangsmåde til behandling
DE50010973D1 (de)	2005-09-22	Pharmazeutische zusammensetzung, enthaltend desoxypeganin zur behandlung des alkoholismus
BRPI0408059A (pt)	2006-02-14	sistema de administração de opióides
BR0005039A (pt)	2003-04-15	Antagonistas do receptor nk-1 e eletriptano para o tratamento da enxaqueca