BG107471A - Indole derivatives useful for the treatment of cns disorders - Google Patents

Indole derivatives useful for the treatment of cns disorders

Info

Publication number: BG107471A
Authority: BG; Bulgaria
Prior art keywords: treatment; cns disorders; indole derivatives; derivatives useful; disorders
Prior art date: 2000-06-29

Application number

BG107471A

Other languages

Bulgarian (bg)

English (en)

Inventor

Benny Bang-Andersen

Jakob Felding

Jan Kehler

Original Assignee

H.Lundbeck A/S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-29

Filing date

2003-01-17

Publication date

2003-10-31

2003-01-17 Application filed by H.Lundbeck A/S filed Critical H.Lundbeck A/S

2003-10-31 Publication of BG107471A publication Critical patent/BG107471A/xx

Links

229940054051 antipsychotic indole derivative Drugs 0.000 title 1
150000002475 indoles Chemical class 0.000 title 1
VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
102000040125 5-hydroxytryptamine receptor family Human genes 0.000 abstract 1
108091032151 5-hydroxytryptamine receptor family Proteins 0.000 abstract 1
208000019901 Anxiety disease Diseases 0.000 abstract 1
208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
208000036864 Attention deficit/hyperactivity disease Diseases 0.000 abstract 1
102000015554 Dopamine receptor Human genes 0.000 abstract 1
108050004812 Dopamine receptor Proteins 0.000 abstract 1
208000019695 Migraine disease Diseases 0.000 abstract 1
208000012902 Nervous system disease Diseases 0.000 abstract 1
208000025966 Neurological disease Diseases 0.000 abstract 1
208000028017 Psychotic disease Diseases 0.000 abstract 1
208000010877 cognitive disease Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229960003638 dopamine Drugs 0.000 abstract 1
239000003446 ligand Substances 0.000 abstract 1
206010027599 migraine Diseases 0.000 abstract 1
208000020016 psychiatric disease Diseases 0.000 abstract 1
201000000980 schizophrenia Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Toxicology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

BG107471A 2000-06-29 2003-01-17 Indole derivatives useful for the treatment of cns disorders BG107471A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA200001018		2000-06-29
PCT/DK2001/000407 WO2002000645A1 (en)	2000-06-29	2001-06-13	Indole derivatives useful for the treatment of cns disorders

Publications (1)

Publication Number	Publication Date
BG107471A true BG107471A (en)	2003-10-31

Family

ID=8159589

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG107471A BG107471A (en)	2000-06-29	2003-01-17	Indole derivatives useful for the treatment of cns disorders

Country Status (23)

Country	Link
US (1)	US20030232822A1 (pl)
EP (1)	EP1299380B1 (pl)
JP (1)	JP2004501912A (pl)
KR (1)	KR20030011365A (pl)
CN (1)	CN1439004A (pl)
AR (1)	AR028736A1 (pl)
AT (1)	ATE268765T1 (pl)
AU (1)	AU2001273882A1 (pl)
BG (1)	BG107471A (pl)
BR (1)	BR0112286A (pl)
CA (1)	CA2414115A1 (pl)
CZ (1)	CZ20024192A3 (pl)
DE (1)	DE60103761D1 (pl)
EA (1)	EA200300084A1 (pl)
HU (1)	HUP0300786A2 (pl)
IL (1)	IL153254A0 (pl)
IS (1)	IS6642A (pl)
MX (1)	MXPA02012506A (pl)
NO (1)	NO20026029D0 (pl)
PL (1)	PL358966A1 (pl)
SK (1)	SK1092003A3 (pl)
WO (1)	WO2002000645A1 (pl)
ZA (1)	ZA200209886B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0117577D0 (en) *	2001-02-16	2001-09-12	Aventis Pharm Prod Inc	Novel heterocyclic substituted carbonyl derivatives and their use as dopamine D receptor ligands
AU2003257407A1 (en) *	2002-08-29	2004-03-19	H. Lundbeck A/S	S-(+)-3-{1-(2-(2,3-dihydro-1h-indol-3-yl)ethyl)-3,6-dihydro-2h-pyridin-4-yl}-6-chloro-1h-indole and acid addition salts thereof
DE102004027358A1 (de) *	2004-06-04	2005-12-29	Abbott Gmbh & Co. Kg	Pyrimidinverbindungen und ihre Verwendung
CA2659412A1 (en)	2006-07-31	2008-02-07	Janssen Pharmaceutica N.V.	Urotensin ii receptor antagonists
SE531698C2 (sv)	2007-07-12	2009-07-07	Respiratorius Ab	Nya bronkdilaterande a,b-omättade amider
FR2953839A1 (fr) *	2009-12-14	2011-06-17	Sanofi Aventis	Nouveaux derives d'(heterocycle-piperidine condensee)-(piperazinyl)-1alcanone ou d'(heterocycle-pyrrolidine condensee)-(piperazinyl)-1alcanone et leur utilisation comme inhibiteurs de p75

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUT71799A (en) *	1993-03-01	1996-02-28	Merck Sharp & Dohme	Pyrrolo-pyridine derivatives, pharmaceutical compositions containing the same, process for producing them
ZA9711376B (en) *	1996-12-20	1998-07-21	Lundbeck & Co As H	Indole or dihydroindole derivatives

2001
- 2001-06-13 SK SK109-2003A patent/SK1092003A3/sk unknown
- 2001-06-13 EP EP01940241A patent/EP1299380B1/en not_active Expired - Lifetime
- 2001-06-13 JP JP2002505393A patent/JP2004501912A/ja not_active Withdrawn
- 2001-06-13 PL PL01358966A patent/PL358966A1/pl not_active Application Discontinuation
- 2001-06-13 IL IL15325401A patent/IL153254A0/xx unknown
- 2001-06-13 AT AT01940241T patent/ATE268765T1/de not_active IP Right Cessation
- 2001-06-13 DE DE60103761T patent/DE60103761D1/de not_active Expired - Fee Related
- 2001-06-13 AU AU2001273882A patent/AU2001273882A1/en not_active Abandoned
- 2001-06-13 KR KR1020027017614A patent/KR20030011365A/ko not_active Withdrawn
- 2001-06-13 BR BR0112286-0A patent/BR0112286A/pt not_active Application Discontinuation
- 2001-06-13 CA CA002414115A patent/CA2414115A1/en not_active Abandoned
- 2001-06-13 CN CN01811847A patent/CN1439004A/zh active Pending
- 2001-06-13 CZ CZ20024192A patent/CZ20024192A3/cs unknown
- 2001-06-13 HU HU0300786A patent/HUP0300786A2/hu unknown
- 2001-06-13 EA EA200300084A patent/EA200300084A1/ru unknown
- 2001-06-13 WO PCT/DK2001/000407 patent/WO2002000645A1/en not_active Ceased
- 2001-06-13 MX MXPA02012506A patent/MXPA02012506A/es unknown
- 2001-06-19 AR ARP010102901A patent/AR028736A1/es unknown
2002
- 2002-11-29 IS IS6642A patent/IS6642A/is unknown
- 2002-12-05 ZA ZA200209886A patent/ZA200209886B/en unknown
- 2002-12-16 NO NO20026029A patent/NO20026029D0/no not_active Application Discontinuation
- 2002-12-17 US US10/327,670 patent/US20030232822A1/en not_active Abandoned
2003
- 2003-01-17 BG BG107471A patent/BG107471A/xx unknown

Also Published As

Publication number	Publication date
MXPA02012506A (es)	2003-04-25
ZA200209886B (en)	2003-12-05
DE60103761D1 (de)	2004-07-15
WO2002000645A1 (en)	2002-01-03
US20030232822A1 (en)	2003-12-18
HUP0300786A2 (hu)	2003-07-28
IS6642A (is)	2002-11-29
IL153254A0 (en)	2003-07-06
AU2001273882A1 (en)	2002-01-08
EA200300084A1 (ru)	2003-06-26
CA2414115A1 (en)	2002-01-03
PL358966A1 (pl)	2004-08-23
ATE268765T1 (de)	2004-06-15
EP1299380B1 (en)	2004-06-09
AR028736A1 (es)	2003-05-21
CZ20024192A3 (cs)	2003-04-16
SK1092003A3 (en)	2003-05-02
KR20030011365A (ko)	2003-02-07
BR0112286A (pt)	2003-05-13
JP2004501912A (ja)	2004-01-22
NO20026029L (no)	2002-12-16
NO20026029D0 (no)	2002-12-16
EP1299380A1 (en)	2003-04-09
CN1439004A (zh)	2003-08-27

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