BG107614A - РЕЦЕПТОР HA EDb - ФИБРОНЕКТИН-ДОМЕНИ - Google Patents

РЕЦЕПТОР HA EDb - ФИБРОНЕКТИН-ДОМЕНИ Download PDF

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Publication number
BG107614A
BG107614A BG107614A BG10761403A BG107614A BG 107614 A BG107614 A BG 107614A BG 107614 A BG107614 A BG 107614A BG 10761403 A BG10761403 A BG 10761403A BG 107614 A BG107614 A BG 107614A
Authority
BG
Bulgaria
Prior art keywords
protein
edb
cells
seq
group
Prior art date
Application number
BG107614A
Other languages
Bulgarian (bg)
English (en)
Inventor
Alexander REDLITZ
Marcus Koppitz
Ursula Egner
Inke Bahr
Andreas Menrad
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10045803A external-priority patent/DE10045803A1/de
Priority claimed from DE2001123133 external-priority patent/DE10123133A1/de
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of BG107614A publication Critical patent/BG107614A/bg

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
BG107614A 2000-09-07 2003-03-06 РЕЦЕПТОР HA EDb - ФИБРОНЕКТИН-ДОМЕНИ BG107614A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10045803A DE10045803A1 (de) 2000-09-07 2000-09-07 Rezeptor der EDb Fibronektin-Domäne
DE2001123133 DE10123133A1 (de) 2001-05-02 2001-05-02 Rezeptor der ED¶b¶-Fibronektin-Domäne (II)
PCT/EP2001/010016 WO2002020563A2 (fr) 2000-09-07 2001-08-30 RECEPTEUR DU DOMAINE DE LA EDb-FIBRONECTINE

Publications (1)

Publication Number Publication Date
BG107614A true BG107614A (bg) 2003-12-31

Family

ID=26007070

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107614A BG107614A (bg) 2000-09-07 2003-03-06 РЕЦЕПТОР HA EDb - ФИБРОНЕКТИН-ДОМЕНИ

Country Status (23)

Country Link
US (3) US20020197700A1 (fr)
EP (1) EP1381629B1 (fr)
JP (1) JP2004529848A (fr)
KR (1) KR20030045056A (fr)
CN (1) CN1246333C (fr)
AT (1) ATE407951T1 (fr)
AU (1) AU1218202A (fr)
BG (1) BG107614A (fr)
BR (1) BR0113737A (fr)
CA (1) CA2421783A1 (fr)
DE (1) DE50114321D1 (fr)
EE (1) EE200300092A (fr)
ES (1) ES2312478T3 (fr)
HR (1) HRP20030263A2 (fr)
HU (1) HUP0300935A3 (fr)
IL (1) IL154778A0 (fr)
NO (1) NO20031033L (fr)
NZ (1) NZ524342A (fr)
PL (1) PL364358A1 (fr)
RU (1) RU2280254C2 (fr)
SK (1) SK2882003A3 (fr)
WO (1) WO2002020563A2 (fr)
YU (1) YU17503A (fr)

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JP2003524018A (ja) 2000-02-24 2003-08-12 アイトゲネーシシェ テクニシェ ホッホシューレ チューリッヒ フィブロネクチンのed‐bドメインに特異的な抗体、前記抗体を含む複合体、および血管形成を検出および治療するためのその使用
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ATE463512T1 (de) 2005-11-09 2010-04-15 Morphosys Ag Identifizierung und charakterisierung von funktionsblockierenden anti-ed-b-fibronektin antikörpern
EP1892248A1 (fr) * 2006-08-21 2008-02-27 Eidgenössische Technische Hochschule Zürich Protéines liantes spécifiques et de haute affinité comprenant des domaines SH3 de FYN kinase modifiés
WO2008120101A2 (fr) 2007-04-02 2008-10-09 Philogen S.P.A. Nouvel antigène associé à la néovasculature de métastases tumorales
US10202442B2 (en) 2007-07-25 2019-02-12 Philogen S.P.A. Antigen associated with lung cancers and lymphomas
DK3281952T3 (da) 2007-10-30 2020-08-03 Philogen Spa Antigen, der er forbundet med reumatoid artritis
ATE548052T1 (de) * 2008-01-17 2012-03-15 Philogen Spa Kombination aus einem anti-edb-fibronectin- antikörper-il-2-fusionsprotein und einem b-zellen bindenden molekül, b-zellen-vorläufern und/oder deren krebserregendem gegenspieler
EP2461832B1 (fr) 2009-08-05 2017-06-28 Philogen S.p.A. Ciblage de la néovascularisation de la moelle osseuse
ES2743423T3 (es) 2012-10-03 2020-02-19 Philogen Spa Conjugado de anticuerpos para su uso en el tratamiento de una enfermedad inflamatoria intestinal
CN111148759B (zh) * 2017-09-30 2023-09-19 合肥立方制药股份有限公司 结合至纤维连接蛋白b结构域的蛋白
EP4384203A4 (fr) * 2021-08-09 2025-09-03 Rajan Gunesh Compositions et procédés de cicatrisation de plaies

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Also Published As

Publication number Publication date
WO2002020563A2 (fr) 2002-03-14
JP2004529848A (ja) 2004-09-30
PL364358A1 (en) 2004-12-13
RU2003109431A (ru) 2005-01-20
ATE407951T1 (de) 2008-09-15
HUP0300935A2 (hu) 2003-12-29
CN1246333C (zh) 2006-03-22
KR20030045056A (ko) 2003-06-09
US20020197700A1 (en) 2002-12-26
HRP20030263A2 (en) 2005-10-31
WO2002020563A3 (fr) 2003-10-09
NO20031033D0 (no) 2003-03-06
IL154778A0 (en) 2003-10-31
DE50114321D1 (de) 2008-10-23
HK1064683A1 (en) 2005-02-04
EP1381629B1 (fr) 2008-09-10
SK2882003A3 (en) 2003-08-05
NO20031033L (no) 2003-05-07
BR0113737A (pt) 2004-02-25
US20050221434A1 (en) 2005-10-06
YU17503A (sh) 2006-05-25
HUP0300935A3 (en) 2005-09-28
NZ524342A (en) 2005-09-30
EE200300092A (et) 2005-06-15
CN1487953A (zh) 2004-04-07
ES2312478T3 (es) 2009-03-01
CA2421783A1 (fr) 2002-03-14
US20050089941A1 (en) 2005-04-28
AU1218202A (en) 2002-03-22
EP1381629A2 (fr) 2004-01-21
RU2280254C2 (ru) 2006-07-20

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