EE200300092A - EDb-fibronektiinidomeeni retseptor - Google Patents

EDb-fibronektiinidomeeni retseptor

Info

Publication number
EE200300092A
EE200300092A EEP200300092A EEP200300092A EE200300092A EE 200300092 A EE200300092 A EE 200300092A EE P200300092 A EEP200300092 A EE P200300092A EE P200300092 A EEP200300092 A EE P200300092A EE 200300092 A EE200300092 A EE 200300092A
Authority
EE
Estonia
Prior art keywords
sub
edb
domain receptor
fibronectin domain
fibronectin domains
Prior art date
Application number
EEP200300092A
Other languages
English (en)
Inventor
Redlitz Alexander
Koppitz Marcus
Egner Ursula
Bahr Inke
Menrad Andreas
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10045803A external-priority patent/DE10045803A1/de
Priority claimed from DE2001123133 external-priority patent/DE10123133A1/de
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of EE200300092A publication Critical patent/EE200300092A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EEP200300092A 2000-09-07 2001-08-30 EDb-fibronektiinidomeeni retseptor EE200300092A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10045803A DE10045803A1 (de) 2000-09-07 2000-09-07 Rezeptor der EDb Fibronektin-Domäne
DE2001123133 DE10123133A1 (de) 2001-05-02 2001-05-02 Rezeptor der ED¶b¶-Fibronektin-Domäne (II)
PCT/EP2001/010016 WO2002020563A2 (de) 2000-09-07 2001-08-30 REZEPTOR DER EDb-FIBRONEKTIN-DOMÄNE (II)

Publications (1)

Publication Number Publication Date
EE200300092A true EE200300092A (et) 2005-06-15

Family

ID=26007070

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300092A EE200300092A (et) 2000-09-07 2001-08-30 EDb-fibronektiinidomeeni retseptor

Country Status (23)

Country Link
US (3) US20020197700A1 (et)
EP (1) EP1381629B1 (et)
JP (1) JP2004529848A (et)
KR (1) KR20030045056A (et)
CN (1) CN1246333C (et)
AT (1) ATE407951T1 (et)
AU (1) AU1218202A (et)
BG (1) BG107614A (et)
BR (1) BR0113737A (et)
CA (1) CA2421783A1 (et)
DE (1) DE50114321D1 (et)
EE (1) EE200300092A (et)
ES (1) ES2312478T3 (et)
HR (1) HRP20030263A2 (et)
HU (1) HUP0300935A3 (et)
IL (1) IL154778A0 (et)
NO (1) NO20031033L (et)
NZ (1) NZ524342A (et)
PL (1) PL364358A1 (et)
RU (1) RU2280254C2 (et)
SK (1) SK2882003A3 (et)
WO (1) WO2002020563A2 (et)
YU (1) YU17503A (et)

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CA2400622A1 (en) 2000-02-24 2001-08-30 Eidgenossische Technische Hochschule Zurich Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis
US7785591B2 (en) * 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
CN101356271A (zh) 2005-11-09 2009-01-28 拜耳先灵医药股份有限公司 功能阻断性抗-ed-b-纤连蛋白抗体的鉴别与鉴定
EP1892248A1 (en) * 2006-08-21 2008-02-27 Eidgenössische Technische Hochschule Zürich Specific and high affinity binding proteins comprising modified SH3 domains of FYN kinase
EP2653478B1 (en) 2007-04-02 2016-10-05 Philogen S.p.A. A novel antigen associated with the neovasculature of tumour metastases
US10202442B2 (en) 2007-07-25 2019-02-12 Philogen S.P.A. Antigen associated with lung cancers and lymphomas
CN101918443B (zh) * 2007-10-30 2013-07-17 菲洛根股份公司 一种与类风湿性关节炎相关的抗原
ES2382058T3 (es) * 2008-01-17 2012-06-04 Philogen S.P.A. Combinación de una proteína de fusión de un anticuerpo dirigido contra el EDB de la fibronectina-IL-2, y una molécula de unión a los linfocitos B, progenitores de los linfocitos B y/o sus homólogos cancerosos
US8679488B2 (en) 2009-08-05 2014-03-25 Philogen S.P.A. Targeting of bone marrow neovasculature
ES2743423T3 (es) 2012-10-03 2020-02-19 Philogen Spa Conjugado de anticuerpos para su uso en el tratamiento de una enfermedad inflamatoria intestinal
WO2019062877A1 (zh) * 2017-09-30 2019-04-04 合肥立方制药股份有限公司 结合至纤维连接蛋白b结构域的蛋白
WO2023015341A1 (en) * 2021-08-09 2023-02-16 The University Of Western Australia Compositions and methods for wound healing

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US5270030A (en) * 1988-12-29 1993-12-14 Bio-Technology General Corp. Fibrin binding domain polypeptide and method of producing
ATE172879T1 (de) * 1989-08-09 1998-11-15 Rhomed Inc Direkte radioetikettierung von antikörpern und sonstigen proteinen mittels technetium oder rhenium
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US5965132A (en) * 1992-03-05 1999-10-12 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
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Also Published As

Publication number Publication date
KR20030045056A (ko) 2003-06-09
US20020197700A1 (en) 2002-12-26
DE50114321D1 (de) 2008-10-23
BR0113737A (pt) 2004-02-25
IL154778A0 (en) 2003-10-31
CN1487953A (zh) 2004-04-07
EP1381629A2 (de) 2004-01-21
BG107614A (bg) 2003-12-31
WO2002020563A2 (de) 2002-03-14
PL364358A1 (en) 2004-12-13
NO20031033L (no) 2003-05-07
US20050089941A1 (en) 2005-04-28
WO2002020563A3 (de) 2003-10-09
US20050221434A1 (en) 2005-10-06
HUP0300935A3 (en) 2005-09-28
HUP0300935A2 (hu) 2003-12-29
RU2003109431A (ru) 2005-01-20
CA2421783A1 (en) 2002-03-14
SK2882003A3 (en) 2003-08-05
YU17503A (sh) 2006-05-25
RU2280254C2 (ru) 2006-07-20
ATE407951T1 (de) 2008-09-15
HK1064683A1 (en) 2005-02-04
CN1246333C (zh) 2006-03-22
AU1218202A (en) 2002-03-22
ES2312478T3 (es) 2009-03-01
HRP20030263A2 (en) 2005-10-31
JP2004529848A (ja) 2004-09-30
NO20031033D0 (no) 2003-03-06
EP1381629B1 (de) 2008-09-10
NZ524342A (en) 2005-09-30

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