BG107743A - Използване на антипрогестини за профилактика и лечение на хормонално зависими заболявания - Google Patents

Използване на антипрогестини за профилактика и лечение на хормонално зависими заболявания Download PDF

Info

Publication number: BG107743A
Authority: BG; Bulgaria
Prior art keywords: antiprogestin; treatment; breast cancer; hormone; tumor
Prior art date: 2000-10-18

Application number

BG107743A

Other languages

Bulgarian (bg)

English (en)

Inventor

Jens Hoffmann

Rosemarie Lichtner

Gerhard Siemeister

Martin Schneider

Ulrike Fuhrmann

Original Assignee

Schering Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-18

Filing date

2003-04-18

Publication date

2004-01-30

2003-04-18 Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft

2004-01-30 Publication of BG107743A publication Critical patent/BG107743A/bg

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BG107743A 2000-10-18 2003-04-18 Използване на антипрогестини за профилактика и лечение на хормонално зависими заболявания BG107743A (bg)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US24099800P	2000-10-18	2000-10-18
EP00250341		2000-10-18
PCT/EP2001/012005 WO2002032430A1 (en)	2000-10-18	2001-10-17	Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases

Publications (1)

Publication Number	Publication Date
BG107743A true BG107743A (bg)	2004-01-30

Family

ID=26072951

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG107743A BG107743A (bg)	2000-10-18	2003-04-18	Използване на антипрогестини за профилактика и лечение на хормонално зависими заболявания

Country Status (26)

Country	Link
US (1)	US7378406B2 (de)
EP (1)	EP1328276B1 (de)
JP (2)	JP2004511522A (de)
KR (1)	KR100632908B1 (de)
CN (1)	CN1512886A (de)
AT (1)	ATE310522T1 (de)
AU (2)	AU2002218243B2 (de)
BG (1)	BG107743A (de)
BR (1)	BR0114665A (de)
CA (1)	CA2423017C (de)
CY (1)	CY1104981T1 (de)
CZ (1)	CZ299942B6 (de)
DE (1)	DE60115274T2 (de)
DK (1)	DK1328276T3 (de)
EE (1)	EE05259B1 (de)
ES (1)	ES2253443T3 (de)
HR (1)	HRP20030387A2 (de)
HU (1)	HUP0301460A3 (de)
IL (2)	IL154975A0 (de)
MX (1)	MXPA03002954A (de)
NO (1)	NO20031740L (de)
NZ (1)	NZ538346A (de)
PL (1)	PL360151A1 (de)
SI (1)	SI1328276T1 (de)
SK (1)	SK287124B6 (de)
WO (1)	WO2002032430A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UY27301A1 (es) *	2001-05-25	2003-02-28	Schering Ag	Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
DE10159217A1 (de)	2001-11-27	2003-06-05	Schering Ag	17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
US20040242551A1 (en) *	2003-05-28	2004-12-02	Schering Ag	Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
US9517240B2 (en) *	2006-09-26	2016-12-13	The Regents Of The University Of California	Methods and compositions for cancer prevention and treatment
US20080261929A1 (en) *	2007-04-23	2008-10-23	Jens Hoffmann	Combination of progesterone-receptor antagonist together with an aromatase inhibitor for use in brca mediated diseases
CA2683809A1 (en) *	2007-04-23	2008-10-30	Bayer Schering Pharma Aktiengesellschaft	Progesterone-receptor antagonist for use in brca alone or as combination with antiestrogen
US20080268041A1 (en) *	2007-04-23	2008-10-30	Jens Hoffmann	Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
TWI477276B (zh) *	2008-04-28	2015-03-21	Repros Therapeutics Inc	抗黃體素給藥方案
TWI539953B (zh) *	2008-04-28	2016-07-01	瑞波若斯治療學公司	用於治療乳癌之組成物和方法
DE102009034367A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034366A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de)	2009-07-21	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de)	2009-07-21	2011-02-10	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102010007722A1 (de)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesteronrezeptorantagonisten
DE102010007719A1 (de)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesteronrezeptorantagonisten
MX2012010327A (es) *	2010-03-22	2012-11-16	Repros Therapeutics Inc	Composiciones y metodos para la administracion no toxica de antiprogestinas.
CA2872644A1 (en)	2012-05-31	2013-12-05	Allergan Pharmaceuticals International Limited	Formulations and methods for vaginal delivery of antiprogestins
US9545411B2 (en)	2012-11-02	2017-01-17	Repros Therapeutics Inc.	Methods and compositions for treating progesterone-dependent conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3733478A1 (de) *	1987-10-01	1989-04-13	Schering Ag	Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
DE19706061A1 (de) *	1997-02-07	1998-08-13	Schering Ag	Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette

2001
- 2001-10-17 CA CA002423017A patent/CA2423017C/en not_active Expired - Fee Related
- 2001-10-17 CZ CZ20031072A patent/CZ299942B6/cs not_active IP Right Cessation
- 2001-10-17 JP JP2002535668A patent/JP2004511522A/ja not_active Ceased
- 2001-10-17 BR BR0114665-3A patent/BR0114665A/pt not_active Application Discontinuation
- 2001-10-17 KR KR1020037005359A patent/KR100632908B1/ko not_active Expired - Fee Related
- 2001-10-17 DK DK01987668T patent/DK1328276T3/da active
- 2001-10-17 EE EEP200300155A patent/EE05259B1/xx not_active IP Right Cessation
- 2001-10-17 HU HU0301460A patent/HUP0301460A3/hu unknown
- 2001-10-17 AT AT01987668T patent/ATE310522T1/de not_active IP Right Cessation
- 2001-10-17 SI SI200130486T patent/SI1328276T1/sl unknown
- 2001-10-17 EP EP01987668A patent/EP1328276B1/de not_active Expired - Lifetime
- 2001-10-17 HR HR20030387A patent/HRP20030387A2/xx not_active Application Discontinuation
- 2001-10-17 IL IL15497501A patent/IL154975A0/xx active IP Right Grant
- 2001-10-17 MX MXPA03002954A patent/MXPA03002954A/es active IP Right Grant
- 2001-10-17 SK SK474-2003A patent/SK287124B6/sk not_active IP Right Cessation
- 2001-10-17 NZ NZ538346A patent/NZ538346A/en unknown
- 2001-10-17 ES ES01987668T patent/ES2253443T3/es not_active Expired - Lifetime
- 2001-10-17 WO PCT/EP2001/012005 patent/WO2002032430A1/en not_active Ceased
- 2001-10-17 US US10/399,320 patent/US7378406B2/en not_active Expired - Fee Related
- 2001-10-17 PL PL36015101A patent/PL360151A1/xx not_active Application Discontinuation
- 2001-10-17 CN CNA018175686A patent/CN1512886A/zh active Pending
- 2001-10-17 AU AU2002218243A patent/AU2002218243B2/en not_active Ceased
- 2001-10-17 AU AU1824302A patent/AU1824302A/xx active Pending
- 2001-10-17 DE DE60115274T patent/DE60115274T2/de not_active Expired - Lifetime
2003
- 2003-03-18 IL IL154975A patent/IL154975A/en not_active IP Right Cessation
- 2003-04-15 NO NO20031740A patent/NO20031740L/no not_active Application Discontinuation
- 2003-04-18 BG BG107743A patent/BG107743A/bg unknown
2006
- 2006-02-22 CY CY20061100251T patent/CY1104981T1/el unknown
2009
- 2009-12-16 JP JP2009284779A patent/JP2010077158A/ja not_active Ceased

Also Published As

Publication number	Publication date
MXPA03002954A (es)	2003-08-07
AU2002218243B2 (en)	2006-07-13
NO20031740L (no)	2003-06-17
CA2423017A1 (en)	2002-04-25
JP2004511522A (ja)	2004-04-15
KR100632908B1 (ko)	2006-10-13
BR0114665A (pt)	2004-01-13
NO20031740D0 (no)	2003-04-15
NZ538346A (en)	2007-03-30
SI1328276T1 (sl)	2006-04-30
DK1328276T3 (da)	2006-04-03
IL154975A0 (en)	2003-10-31
JP2010077158A (ja)	2010-04-08
IL154975A (en)	2007-05-15
CN1512886A (zh)	2004-07-14
DE60115274D1 (de)	2005-12-29
CA2423017C (en)	2009-01-06
KR20030044007A (ko)	2003-06-02
HRP20030387A2 (en)	2005-04-30
CY1104981T1 (el)	2010-03-03
HUP0301460A3 (en)	2010-01-28
HUP0301460A2 (hu)	2003-10-28
WO2002032430A1 (en)	2002-04-25
ES2253443T3 (es)	2006-06-01
PL360151A1 (en)	2004-09-06
AU1824302A (en)	2002-04-29
EE05259B1 (et)	2010-02-15
DE60115274T2 (de)	2006-07-27
ATE310522T1 (de)	2005-12-15
EE200300155A (et)	2003-08-15
SK4742003A3 (en)	2004-09-08
CZ299942B6 (cs)	2008-12-29
US7378406B2 (en)	2008-05-27
EP1328276A1 (de)	2003-07-23
US20040048841A1 (en)	2004-03-11
EP1328276B1 (de)	2005-11-23
SK287124B6 (sk)	2009-12-07

Publication	Publication Date	Title
JP2010077158A (ja)	2010-04-08	ホルモン−依存性疾病の予防及び処理のための抗黄体ホルモンの使用
AU2002218243A1 (en)	2002-07-04	Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases
KR20060005412A (ko)	2006-01-17	호르몬-의존성 질환의 예방 및 치료를 위한 항프로게스틴및 순수한 항에스트로겐을 포함하는 조성물
EP1326617B1 (de)	2006-08-02	Verwendung von 11beta-(4-acetylphenyl)-17beta-hydroxy-17alpha-(1,1,2,2-pentafluoroethyl)estra-4,9-dien-3-on zur herstellung eines medikaments zur behandlung von brust-, eierstock-, endometrium-krebs, myelom und meningiom
AU2002223619A1 (en)	2002-07-04	Use of antiprogestins for the induction of apoptosis in a cell
US20040072811A1 (en)	2004-04-15	Use of antiprogestins for the induction of apoptosis in a cell
US20080268041A1 (en)	2008-10-30	Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
ZA200303793B (en)	2004-08-16	Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases.
TWI312680B (en)	2009-08-01	Use of antiprogesting for prophylaxis and treatment of hormone-dependent diseases
HK1068098A (en)	2005-04-22	Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases