BG108702A - New anhydrous crystalline forms of gabapentin - Google Patents
New anhydrous crystalline forms of gabapentinInfo
- Publication number
- BG108702A BG108702A BG108702A BG10870204A BG108702A BG 108702 A BG108702 A BG 108702A BG 108702 A BG108702 A BG 108702A BG 10870204 A BG10870204 A BG 10870204A BG 108702 A BG108702 A BG 108702A
- Authority
- BG
- Bulgaria
- Prior art keywords
- gabapentin
- crystalline forms
- anhydrous crystalline
- new anhydrous
- new
- Prior art date
Links
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 4
- 229960002870 gabapentin Drugs 0.000 title abstract 2
- WRSFRDZQQUAKNA-UHFFFAOYSA-N 2-[1-(aminomethyl)cyclohexyl]acetic acid;hydrate Chemical compound O.OC(=O)CC1(CN)CCCCC1 WRSFRDZQQUAKNA-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32837501P | 2001-10-09 | 2001-10-09 | |
| US10/256,155 US6800782B2 (en) | 2001-10-09 | 2002-09-25 | Anhydrous crystalline forms of gabapentin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG108702A true BG108702A (en) | 2005-05-31 |
Family
ID=26945177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG108702A BG108702A (en) | 2001-10-09 | 2004-04-28 | New anhydrous crystalline forms of gabapentin |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6800782B2 (fr) |
| EP (1) | EP1463712A1 (fr) |
| JP (1) | JP2005505594A (fr) |
| KR (1) | KR20050033525A (fr) |
| CN (1) | CN1568305A (fr) |
| AP (1) | AP2004003025A0 (fr) |
| BG (1) | BG108702A (fr) |
| BR (1) | BR0213156A (fr) |
| CA (1) | CA2462331A1 (fr) |
| CO (1) | CO5570697A2 (fr) |
| CZ (1) | CZ2004416A3 (fr) |
| EA (1) | EA006557B1 (fr) |
| GE (1) | GEP20063936B (fr) |
| HR (1) | HRP20040408A2 (fr) |
| HU (1) | HUP0401782A3 (fr) |
| IL (1) | IL161099A0 (fr) |
| IS (1) | IS7195A (fr) |
| MA (1) | MA27072A1 (fr) |
| MX (1) | MXPA04003301A (fr) |
| NO (1) | NO20041370L (fr) |
| NZ (1) | NZ531993A (fr) |
| OA (1) | OA12665A (fr) |
| PL (1) | PL368117A1 (fr) |
| RS (1) | RS28204A (fr) |
| SK (1) | SK1572004A3 (fr) |
| TN (1) | TNSN04055A1 (fr) |
| WO (1) | WO2003031391A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070043236A1 (en) * | 2003-05-19 | 2007-02-22 | Chandiran Thakashina M | Process for preparation of gabapentin |
| WO2004106281A1 (fr) * | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Gabapentine cristallin |
| WO2004110342A2 (fr) * | 2003-06-12 | 2004-12-23 | Matrix Laboratories Ltd | Nouveau polymorphe de gabapentine et sa conversion en gabapentine de forme ii |
| US7169812B2 (en) * | 2003-07-01 | 2007-01-30 | Medtronic, Inc. | Process for producing injectable gabapentin compositions |
| ITMI20040579A1 (it) * | 2004-03-25 | 2004-06-25 | Zambon Spa | Processo di preparazione di gabapentina |
| WO2010023694A2 (fr) * | 2008-09-01 | 2010-03-04 | Hikal Ltd | Formes cristallines de la gabapentine et leur procédé |
| CN104649921B (zh) * | 2015-01-14 | 2016-09-28 | 天津大学 | 一种加巴喷丁与己二酸共晶及其制备方法 |
| CN116693410B (zh) * | 2023-06-08 | 2024-06-07 | 浙江竹子制药有限公司 | 一种粒径可控的加巴喷丁制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
| JPS62247160A (ja) * | 1986-03-31 | 1987-10-28 | Aisin Seiki Co Ltd | スタ−リングエンジンの始動装置 |
| US4894476A (en) * | 1988-05-02 | 1990-01-16 | Warner-Lambert Company | Gabapentin monohydrate and a process for producing the same |
| US4960931A (en) * | 1988-05-02 | 1990-10-02 | Warner-Lambert Company | Gabapentin mohohydrate and a process for producing the same |
| DE3928184A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte |
| IL119890A (en) | 1996-12-24 | 2002-03-10 | Teva Pharma | Gabapentin form iii and preparation of gabapentin form ii |
| ES2137137B1 (es) | 1998-05-25 | 2000-08-16 | Medichem Sa | Nuevo polimorfo de gabapentina no hidratada, su procedimiento de obtencion y su utilizacion para la obtencion de gabapentina de calidad farmaceutica. |
-
2002
- 2002-09-25 US US10/256,155 patent/US6800782B2/en not_active Expired - Fee Related
- 2002-10-03 EP EP02766485A patent/EP1463712A1/fr not_active Withdrawn
- 2002-10-03 HU HU0401782A patent/HUP0401782A3/hu unknown
- 2002-10-03 OA OA1200400095A patent/OA12665A/en unknown
- 2002-10-03 CA CA002462331A patent/CA2462331A1/fr not_active Abandoned
- 2002-10-03 CZ CZ2004416A patent/CZ2004416A3/cs unknown
- 2002-10-03 EA EA200400417A patent/EA006557B1/ru not_active IP Right Cessation
- 2002-10-03 AP APAP/P/2004/003025A patent/AP2004003025A0/en unknown
- 2002-10-03 WO PCT/US2002/031706 patent/WO2003031391A1/fr not_active Ceased
- 2002-10-03 HR HR20040408A patent/HRP20040408A2/hr not_active Application Discontinuation
- 2002-10-03 JP JP2003534375A patent/JP2005505594A/ja active Pending
- 2002-10-03 BR BR0213156-0A patent/BR0213156A/pt not_active IP Right Cessation
- 2002-10-03 MX MXPA04003301A patent/MXPA04003301A/es active IP Right Grant
- 2002-10-03 KR KR1020047005149A patent/KR20050033525A/ko not_active Ceased
- 2002-10-03 SK SK157-2004A patent/SK1572004A3/sk not_active Application Discontinuation
- 2002-10-03 PL PL02368117A patent/PL368117A1/xx not_active Application Discontinuation
- 2002-10-03 RS YU28204A patent/RS28204A/sr unknown
- 2002-10-03 CN CNA02820056XA patent/CN1568305A/zh active Pending
- 2002-10-03 GE GE5594A patent/GEP20063936B/en unknown
- 2002-10-03 IL IL16109902A patent/IL161099A0/xx unknown
- 2002-10-03 NZ NZ531993A patent/NZ531993A/en unknown
-
2004
- 2004-03-23 IS IS7195A patent/IS7195A/is unknown
- 2004-04-01 NO NO20041370A patent/NO20041370L/no not_active Application Discontinuation
- 2004-04-05 MA MA27606A patent/MA27072A1/fr unknown
- 2004-04-06 CO CO04032599A patent/CO5570697A2/es not_active Application Discontinuation
- 2004-04-07 TN TNP2004000055A patent/TNSN04055A1/fr unknown
- 2004-04-28 BG BG108702A patent/BG108702A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20040408A2 (en) | 2004-10-31 |
| GEP20063936B (en) | 2006-10-10 |
| HUP0401782A2 (hu) | 2005-10-28 |
| MXPA04003301A (es) | 2004-07-23 |
| HUP0401782A3 (en) | 2006-01-30 |
| EA200400417A1 (ru) | 2004-10-28 |
| EP1463712A1 (fr) | 2004-10-06 |
| IL161099A0 (en) | 2004-08-31 |
| BR0213156A (pt) | 2004-09-14 |
| CO5570697A2 (es) | 2005-10-31 |
| US20030092933A1 (en) | 2003-05-15 |
| RS28204A (sr) | 2006-12-15 |
| NO20041370L (no) | 2004-04-01 |
| CZ2004416A3 (cs) | 2005-03-16 |
| CN1568305A (zh) | 2005-01-19 |
| TNSN04055A1 (fr) | 2006-06-01 |
| PL368117A1 (en) | 2005-03-21 |
| OA12665A (en) | 2006-06-19 |
| KR20050033525A (ko) | 2005-04-12 |
| SK1572004A3 (sk) | 2005-03-04 |
| AP2004003025A0 (en) | 2004-06-30 |
| MA27072A1 (fr) | 2004-12-20 |
| CA2462331A1 (fr) | 2003-04-17 |
| US6800782B2 (en) | 2004-10-05 |
| WO2003031391A1 (fr) | 2003-04-17 |
| NZ531993A (en) | 2006-09-29 |
| IS7195A (is) | 2004-03-23 |
| JP2005505594A (ja) | 2005-02-24 |
| EA006557B1 (ru) | 2006-02-24 |
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