BG108801A - Process for the preparation of pharmaceutical intermediates - Google Patents
Process for the preparation of pharmaceutical intermediatesInfo
- Publication number
- BG108801A BG108801A BG108801A BG10880104A BG108801A BG 108801 A BG108801 A BG 108801A BG 108801 A BG108801 A BG 108801A BG 10880104 A BG10880104 A BG 10880104A BG 108801 A BG108801 A BG 108801A
- Authority
- BG
- Bulgaria
- Prior art keywords
- preparation
- general formula
- pharmaceutical intermediates
- dimethoxy
- tofisopam
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000012450 pharmaceutical intermediate Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- RUJBDQSFYCKFAA-UHFFFAOYSA-N Tofisopam Chemical compound N=1N=C(C)C(CC)C2=CC(OC)=C(OC)C=C2C=1C1=CC=C(OC)C(OC)=C1 RUJBDQSFYCKFAA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 229960002501 tofisopam Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0105326A HU225411B1 (en) | 2001-12-13 | 2001-12-13 | Process for producing tofisopam |
| HU0105327A HUP0105327A3 (en) | 2001-12-13 | 2001-12-13 | Process for the production of 3-[2-(3,4-dimethoxybenzoyl)-4,5-dimethoxyphenyl]-pentane-2-one |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG108801A true BG108801A (en) | 2005-04-30 |
Family
ID=89979996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG108801A BG108801A (en) | 2001-12-13 | 2004-07-13 | Process for the preparation of pharmaceutical intermediates |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1465879A2 (cs) |
| AU (1) | AU2002348942A1 (cs) |
| BG (1) | BG108801A (cs) |
| CZ (1) | CZ2004792A3 (cs) |
| PL (1) | PL370036A1 (cs) |
| SK (1) | SK2792004A3 (cs) |
| WO (1) | WO2003050092A2 (cs) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU227044B1 (en) * | 2002-12-16 | 2010-05-28 | Egis Gyogyszergyar Nyilvanosan | Process for producing 3-[2-(3,4-dimethoxybenzoyl)-4,5-dimethoxyphenyl]-pentan-2-one |
| FR2996845A1 (fr) * | 2012-10-12 | 2014-04-18 | Servier Lab | Nouveau procede de synthese du 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA712798B (en) * | 1970-11-06 | 1972-02-23 | Egyt Gyogyszervegyeszeti Gyar | New,pharmaceutically active 2,3-diazabicyclo(5.4.0)undecapentaene derivative and process for preparing same |
-
2002
- 2002-12-12 PL PL02370036A patent/PL370036A1/xx unknown
- 2002-12-12 CZ CZ2004792A patent/CZ2004792A3/cs unknown
- 2002-12-12 SK SK279-2004A patent/SK2792004A3/sk unknown
- 2002-12-12 WO PCT/HU2002/000141 patent/WO2003050092A2/en not_active Ceased
- 2002-12-12 AU AU2002348942A patent/AU2002348942A1/en not_active Abandoned
- 2002-12-12 EP EP02781451A patent/EP1465879A2/en not_active Withdrawn
-
2004
- 2004-07-13 BG BG108801A patent/BG108801A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002348942A1 (en) | 2003-06-23 |
| WO2003050092A3 (en) | 2003-11-06 |
| CZ2004792A3 (cs) | 2004-12-15 |
| EP1465879A2 (en) | 2004-10-13 |
| SK2792004A3 (en) | 2004-11-03 |
| WO2003050092A2 (en) | 2003-06-19 |
| AU2002348942A8 (en) | 2003-06-23 |
| PL370036A1 (en) | 2005-05-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69831868D1 (en) | Antithrombosemittel | |
| EP1132387A4 (en) | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL / HORTICULTURAL FUNGICIDES | |
| ZA969622B (en) | Oxazolidinone antibacterial agents having a six-membered heteroaromatic ring. | |
| BG106340A (en) | Substituted oxoazaheterocyclyl compounds | |
| GR3034398T3 (en) | 2-[1',2',4'-triazol-3'-yloxymethylene]-anilides and their use as pest-control agents | |
| HUP0302345A2 (hu) | Új triazolo-pirimidin-vegyületek, ezek intermedierjei és eljárás az előállításukra | |
| MY141255A (en) | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs | |
| NO20014194D0 (no) | Regioselektiv syntese av DTPA-derivater | |
| SG144736A1 (en) | Synthesis of temozolomide and analogs | |
| NO20043765L (no) | Tricykliske triazolbenzazepinderivater, fremgangsmate til fremstilling derav, samt antiallergiske midler | |
| SG143062A1 (en) | Synthesis of temozolomide and analogs | |
| PL367774A1 (en) | Synthesis and intermediates | |
| DE60114640D1 (en) | Antithrombosemittel | |
| JO2251B1 (en) | A multi-step method for preparing derivatives of 5.4-dichromic amino acid | |
| BG108801A (en) | Process for the preparation of pharmaceutical intermediates | |
| WO2001056992A3 (en) | Dibenzo (b,f) azepine intermediates | |
| PL361850A1 (en) | Novel lipoic acid heterocyclic or benzene derivatives, preparation and use thereof as medicines | |
| IL141394A0 (en) | Process for the preparation of imidazodiazepine intermediates | |
| MY129094A (en) | Condensed polycyclic compounds | |
| AU3590801A (en) | One-pot synthesis of alkyl 3-cyclopropylamino-2-(2,4-dibromo-3-(difluoromethoxy)benzoyl -2-propenoate as a useful intermediate for antibacterial quinolone medicaments | |
| MXPA03009639A (es) | Uso de derivados de piridoindolona para preparar medicinas anticancer. | |
| WO2001070744A3 (en) | Process for the preparation of midazolam | |
| WO2002069909A3 (en) | Synthesis of ketosulfone esters | |
| AU2001253602A1 (en) | Synthesis of intermediates useful in preparing tricyclic compounds | |
| WO1999057095A3 (en) | Process for the preparation of a pharmaceutical intermediate |