BG20593A3 - Метод за получаване на тиено<3,2-д>пиримидини - Google Patents

Метод за получаване на тиено<3,2-д>пиримидини

Info

Publication number
BG20593A3
BG20593A3 BG020371A BG2037172A BG20593A3 BG 20593 A3 BG20593 A3 BG 20593A3 BG 020371 A BG020371 A BG 020371A BG 2037172 A BG2037172 A BG 2037172A BG 20593 A3 BG20593 A3 BG 20593A3
Authority
BG
Bulgaria
Prior art keywords
pyrimidines
thieno
obtaining
obtaining thieno
Prior art date
Application number
BG020371A
Other languages
Bulgarian (bg)
English (en)
Inventor
Berthold Narr
Josef Roch
Erich Muller
Josef Nickl
Original Assignee
Dr. Karl Thomae Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712121950 external-priority patent/DE2121950A1/de
Priority claimed from DE19712137341 external-priority patent/DE2137341A1/de
Priority claimed from DE19722215299 external-priority patent/DE2215299A1/de
Application filed by Dr. Karl Thomae Gmbh filed Critical Dr. Karl Thomae Gmbh
Publication of BG20593A3 publication Critical patent/BG20593A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG020371A 1971-05-04 1972-05-03 Метод за получаване на тиено<3,2-д>пиримидини BG20593A3 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19712121950 DE2121950A1 (en) 1971-05-04 1971-05-04 Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
DE19712137341 DE2137341A1 (de) 1971-07-26 1971-07-26 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine
DE19722215299 DE2215299A1 (de) 1972-03-29 1972-03-29 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine

Publications (1)

Publication Number Publication Date
BG20593A3 true BG20593A3 (bg) 1975-12-05

Family

ID=27183398

Family Applications (1)

Application Number Title Priority Date Filing Date
BG020371A BG20593A3 (bg) 1971-05-04 1972-05-03 Метод за получаване на тиено<3,2-д>пиримидини

Country Status (15)

Country Link
US (1) US3888851A (fr)
AT (1) AT318619B (fr)
AU (1) AU4181572A (fr)
BE (1) BE783044A (fr)
BG (1) BG20593A3 (fr)
DD (1) DD97656A5 (fr)
DK (1) DK129844B (fr)
ES (1) ES402302A1 (fr)
FR (1) FR2135294B1 (fr)
GB (1) GB1393161A (fr)
HU (1) HU163960B (fr)
IL (1) IL39341A (fr)
NL (1) NL7206041A (fr)
PL (1) PL82381B1 (fr)
RO (1) RO62428A (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054656A (en) * 1975-09-10 1977-10-18 Mead Johnson & Company Thieno[2,3-d]pyrimidine antiallergic agents
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
CA2129337A1 (fr) * 1992-02-19 1993-09-02 Jotham W. Coe Composes heterocycliques pour ameliorer l'activite antitumorale
PL340412A1 (en) 1997-10-20 2001-01-29 Hoffmann La Roche Bicyclic kinase inhibitors
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
CN101163706A (zh) * 2005-04-21 2008-04-16 贝林格尔·英格海姆国际有限公司 用于治疗炎性疾病的二氢噻吩并嘧啶
PL2041139T3 (pl) 2006-04-26 2012-05-31 Hoffmann La Roche Związki farmaceutyczne
MX2008013583A (es) 2006-04-26 2008-10-31 Genentech Inc Compuestos del inhibidor de fosfoinositido 3-cinasa y composiciones farmaceuticas que los contienen.
KR101533461B1 (ko) 2006-04-26 2015-07-02 에프. 호프만-라 로슈 아게 Pi3k저해제로 유용한 티에노[3,2-d]피리미딘 유도체
AR064154A1 (es) * 2006-12-07 2009-03-18 Piramed Ltd Compuestos inhibidores de fodfoinostida 3- quinasas y composiciones farmaceuticas
PE20081679A1 (es) 2006-12-07 2008-12-18 Hoffmann La Roche Compuestos del inhibidor de fosfoinositida 3-cinasa y metodos de uso
JP5736171B2 (ja) 2007-09-24 2015-06-17 ジェネンテック, インコーポレイテッド チアゾロピリミジンpi3k阻害剤化合物および使用方法
JP5341899B2 (ja) * 2007-10-19 2013-11-13 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ヘテロ環置換ピペラジノ−ジヒドロチエノピリミジン
EP2214675B1 (fr) 2007-10-25 2013-11-20 Genentech, Inc. Procédé de préparation de composés de thiénopyrimidine
GB0721095D0 (en) 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
BRPI1006189A2 (pt) 2009-03-12 2020-08-18 Genentech Inc uso de uma combinação terapêutica, formulação farmacêutica, artigo de manufatura, produto, método para determinar compostos a serem utilizados em combinação para o tratamento de uma malignidade hematopoiética e método para selecionar compostos a serem utilizados em combinação para o tratamento de câncer
US8173650B2 (en) 2009-05-27 2012-05-08 Genentech, Inc. Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
WO2010136491A1 (fr) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Composés bicycliques indole-pyrimidine inhibiteurs de pi3k sélectifs pour p110 delta et leurs procédés d'utilisation
CN103038643A (zh) 2010-04-16 2013-04-10 基因泰克公司 作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
WO2012088254A1 (fr) 2010-12-22 2012-06-28 Genentech, Inc. Polythérapie par inducteur et inhibiteur d'autophagie pour le traitement de néoplasmes
WO2014130923A2 (fr) 2013-02-25 2014-08-28 Genentech, Inc. Procédés et compositions pour détecter et traiter un mutant d'akt résistant aux médicaments
GB201410816D0 (en) * 2014-06-17 2014-07-30 Ucb Biopharma Sprl And Katholieke Universiteit Leuven Therapeutic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
US3210368A (en) * 1964-09-29 1965-10-05 Ciba Geigy Corp Certain 2-amino-4-aryl-5-n, n-disubstituted amino-lower alkyl-thiazole compounds

Also Published As

Publication number Publication date
AU4181572A (en) 1973-11-08
ES402302A1 (es) 1975-04-01
GB1393161A (en) 1975-05-07
HU163960B (fr) 1973-11-28
PL82381B1 (fr) 1975-10-31
IL39341A (en) 1975-08-31
DK129844C (fr) 1975-05-12
NL7206041A (fr) 1972-11-07
AT318619B (de) 1974-11-11
RO62428A (fr) 1978-01-15
DD97656A5 (fr) 1973-05-12
US3888851A (en) 1975-06-10
IL39341A0 (en) 1972-07-26
FR2135294B1 (fr) 1975-10-17
BE783044A (fr) 1972-11-06
DK129844B (da) 1974-11-25
FR2135294A1 (fr) 1972-12-15

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