BG27902A3 - Метод за получаване на n-(метокси-метил-фуриметил)-6,7-бензоморфани и морфипани - Google Patents

Метод за получаване на n-(метокси-метил-фуриметил)-6,7-бензоморфани и морфипани

Info

Publication number
BG27902A3
BG27902A3 BG028037A BG2803774A BG27902A3 BG 27902 A3 BG27902 A3 BG 27902A3 BG 028037 A BG028037 A BG 028037A BG 2803774 A BG2803774 A BG 2803774A BG 27902 A3 BG27902 A3 BG 27902A3
Authority
BG
Bulgaria
Prior art keywords
benzomorphanes
morphipanes
furimethyl
methoxy
methyl
Prior art date
Application number
BG028037A
Other languages
English (en)
Inventor
Herbert Merz
Adolf Longbein
Gerhard Walter
Klaus Stokhaus
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG27902A3 publication Critical patent/BG27902A3/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Метод за получаване на охарактеризирани и доказани в описанието n-(метоксиметил-фурилметил)-6, 7-бензоморфани и -морфинани с обща формула........ Патентните претенции са формулирани в 2 точки
BG028037A 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фуриметил)-6,7-бензоморфани и морфипани BG27902A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732354002 DE2354002A1 (de) 1973-10-27 1973-10-27 Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BG27902A3 true BG27902A3 (bg) 1980-01-15

Family

ID=5896658

Family Applications (3)

Application Number Title Priority Date Filing Date
BG028036A BG27901A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи
BG028038A BG27903A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурилметил)-6,7-бензоморфани и морфипани и техните присъединителни с киселина соли
BG028037A BG27902A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фуриметил)-6,7-бензоморфани и морфипани

Family Applications Before (2)

Application Number Title Priority Date Filing Date
BG028036A BG27901A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи
BG028038A BG27903A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурилметил)-6,7-бензоморфани и морфипани и техните присъединителни с киселина соли

Country Status (27)

Country Link
US (1) US3981874A (bg)
JP (1) JPS5738590B2 (bg)
AT (6) AT335631B (bg)
BE (1) BE821505A (bg)
BG (3) BG27901A3 (bg)
CA (1) CA1056377A (bg)
CH (6) CH609048A5 (bg)
CS (3) CS171194B2 (bg)
DD (1) DD115909A5 (bg)
DE (1) DE2354002A1 (bg)
DK (1) DK138325C (bg)
ES (6) ES431055A1 (bg)
FI (1) FI62079C (bg)
FR (1) FR2248838B1 (bg)
GB (1) GB1482552A (bg)
HU (1) HU176479B (bg)
IE (1) IE41528B1 (bg)
IL (1) IL45938A (bg)
NL (1) NL7413980A (bg)
NO (1) NO140859C (bg)
PH (1) PH11894A (bg)
PL (3) PL92053B1 (bg)
RO (5) RO65656A (bg)
SE (1) SE422791B (bg)
SU (6) SU511005A3 (bg)
YU (5) YU36950B (bg)
ZA (1) ZA746790B (bg)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
US8575156B2 (en) 2007-07-26 2013-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
CL2008003407A1 (es) * 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
WO2009100872A1 (en) * 2008-02-12 2009-08-20 Boehringer Ingelheim International Gmbh Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
NZ588954A (en) 2008-05-01 2012-08-31 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW201004945A (en) 2008-05-01 2010-02-01 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CN104327062A (zh) 2008-07-25 2015-02-04 贝林格尔·英格海姆国际有限公司 11β-羟基类固醇脱氢酶1的环状抑制剂
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632591A (en) * 1968-07-19 1972-01-04 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) * 1968-12-26 1974-09-03 Sumitomo Chemical Co 2-aroylalkyl benzomorphans
CS166804B2 (bg) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim

Also Published As

Publication number Publication date
SU508193A3 (ru) 1976-03-25
HU176479B (en) 1981-03-28
IE41528L (en) 1975-04-27
ES431059A1 (es) 1976-10-16
FI314174A7 (bg) 1975-04-28
ATA828874A (de) 1976-06-15
SE422791B (sv) 1982-03-29
YU285274A (en) 1982-02-25
IL45938A (en) 1977-12-30
AT335634B (de) 1977-03-25
PL92052B1 (bg) 1977-03-31
PL92053B1 (bg) 1977-03-31
YU285174A (en) 1982-06-18
SE7413485L (bg) 1975-04-28
GB1482552A (en) 1977-08-10
YU36952B (en) 1984-08-31
RO65657A (ro) 1980-06-15
PL92086B1 (bg) 1977-03-31
YU36949B (en) 1984-08-31
DK138325C (da) 1979-01-22
YU285374A (en) 1982-06-18
ATA828974A (de) 1976-08-15
SU508192A3 (ru) 1976-03-25
SU511005A3 (ru) 1976-04-15
YU285474A (en) 1982-06-18
NL7413980A (nl) 1975-04-29
US3981874A (en) 1976-09-21
NO140859C (no) 1979-11-28
YU285674A (en) 1982-06-18
ATA828574A (de) 1976-07-15
ATA829074A (de) 1976-07-15
ZA746790B (en) 1976-06-30
IL45938A0 (en) 1974-12-31
BG27901A3 (bg) 1980-01-15
AT335076B (de) 1977-02-25
NO743845L (bg) 1975-05-26
AT335631B (de) 1977-03-25
IE41528B1 (en) 1980-01-30
SU578870A3 (ru) 1977-10-30
FR2248838A1 (bg) 1975-05-23
YU36950B (en) 1984-08-31
RO65659A (ro) 1980-06-15
CA1056377A (en) 1979-06-12
SU510999A3 (ru) 1976-04-15
ES431056A1 (es) 1976-10-16
YU36519B (en) 1984-02-29
BE821505A (fr) 1975-04-25
JPS5071679A (bg) 1975-06-13
SU512707A3 (ru) 1976-04-30
ATA828774A (de) 1976-07-15
FI62079C (fi) 1982-11-10
PH11894A (en) 1978-08-29
CH609046A5 (bg) 1979-02-15
YU36951B (en) 1984-08-31
CS171194B2 (bg) 1976-10-29
FR2248838B1 (bg) 1977-11-04
CS171196B2 (bg) 1976-10-29
CH609685A5 (bg) 1979-03-15
DE2354002A1 (de) 1975-05-07
JPS5738590B2 (bg) 1982-08-16
AT336202B (de) 1977-04-25
RO65655A (ro) 1980-06-15
CH609686A5 (bg) 1979-03-15
CS171195B2 (bg) 1976-10-29
RO65658A (fr) 1979-07-15
CH609048A5 (bg) 1979-02-15
ES431055A1 (es) 1976-10-16
NO140859B (no) 1979-08-20
AT335632B (de) 1977-03-25
ATA828674A (de) 1976-07-15
FI62079B (fi) 1982-07-30
BG27903A3 (bg) 1980-01-15
RO65656A (ro) 1980-06-15
CH609340A5 (bg) 1979-02-28
ES431054A1 (es) 1976-10-16
DK559874A (bg) 1975-06-23
AT335633B (de) 1977-03-25
DD115909A5 (bg) 1975-10-20
ES431058A1 (es) 1976-10-16
CH609047A5 (bg) 1979-02-15
DK138325B (da) 1978-08-14
ES431057A1 (es) 1976-10-16

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