BG32714A3 - Метод за получаване на 7,8-дихлор-1,2,3,4-тетра-хидроизохинолин - Google Patents

Метод за получаване на 7,8-дихлор-1,2,3,4-тетра-хидроизохинолин

Info

Publication number: BG32714A3
Authority: BG; Bulgaria
Prior art keywords: dichloro; hydroisoquinoline; tetra; preparation; dichlorobenzylamine
Prior art date: 1978-08-10

Application number

BG044609A

Other languages

Bulgarian (bg)

English (en)

Inventor

Bing Lam

Wilford Mendelson

Charles Spainhour

Original Assignee

Smithkline Beecham Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-08-10

Filing date

1979-08-10

Publication date

1982-09-15

1979-08-10 Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation

1982-09-15 Publication of BG32714A3 publication Critical patent/BG32714A3/xx

Links

WFPUBEDBBOGGIQ-UHFFFAOYSA-N 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline Chemical compound C1CNCC2=C(Cl)C(Cl)=CC=C21 WFPUBEDBBOGGIQ-UHFFFAOYSA-N 0.000 title abstract 2
VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
229910052783 alkali metal Inorganic materials 0.000 abstract 1
150000001340 alkali metals Chemical class 0.000 abstract 1
-1 ammonium halide Chemical class 0.000 abstract 1
239000002585 base Substances 0.000 abstract 1
230000003197 catalytic effect Effects 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Obesity (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BG044609A 1978-08-10 1979-08-10 Метод за получаване на 7,8-дихлор-1,2,3,4-тетра-хидроизохинолин BG32714A3 (bg)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/932,586 US4251660A (en)	1978-08-10	1978-08-10	Method for preparing tetrahydroisoquinolines

Publications (1)

Publication Number	Publication Date
BG32714A3 true BG32714A3 (bg)	1982-09-15

Family

ID=25462546

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG044609A BG32714A3 (bg)	1978-08-10	1979-08-10	Метод за получаване на 7,8-дихлор-1,2,3,4-тетра-хидроизохинолин

Country Status (29)

Country	Link
US (1)	US4251660A (cs)
EP (1)	EP0008405B1 (cs)
JP (1)	JPS5524196A (cs)
AR (1)	AR220218A1 (cs)
AT (1)	ATE258T1 (cs)
AU (1)	AU522843B2 (cs)
BG (1)	BG32714A3 (cs)
CA (1)	CA1130290A (cs)
CS (1)	CS226006B2 (cs)
DD (1)	DD145532A5 (cs)
DE (1)	DE2961141D1 (cs)
DK (1)	DK330579A (cs)
ES (1)	ES483151A1 (cs)
FI (1)	FI65062C (cs)
GR (1)	GR69853B (cs)
HU (1)	HU178110B (cs)
IE (1)	IE48618B1 (cs)
IL (1)	IL57980A (cs)
IN (1)	IN152421B (cs)
IT (1)	IT1227791B (cs)
MX (1)	MX5581E (cs)
NO (1)	NO153807C (cs)
NZ (1)	NZ191227A (cs)
PH (1)	PH24441A (cs)
PL (1)	PL217684A1 (cs)
PT (1)	PT70029A (cs)
RO (1)	RO78160A (cs)
SU (1)	SU860698A3 (cs)
ZA (1)	ZA793308B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3272044D1 (de) *	1981-11-27	1986-08-21	Smithkline Beckman Corp	3-benzazepines as alpha-2 antagonists
US4541954A (en) *	1984-09-05	1985-09-17	Smithkline Beckman Corporation	Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2771468A (en) *	1954-02-19	1956-11-20	Sterling Drug Inc	4-aralkyl-3-morpholones, 4-aralkyl-3-homomorpholones and their preparation
US3947456A (en) *	1970-01-06	1976-03-30	Hoffman-La Roche Inc.	Substituted 4-phenyl isoquinolines
US3752892A (en) *	1970-03-11	1973-08-14	Ciba Geigy Corp	Anorexigenic tetrahydrobenzazepine derivative method and composition thereof

1978
- 1978-08-10 US US05/932,586 patent/US4251660A/en not_active Expired - Lifetime
1979
- 1979-06-27 IN IN470/DEL/79A patent/IN152421B/en unknown
- 1979-07-03 ZA ZA793308A patent/ZA793308B/xx unknown
- 1979-08-02 IT IT7924894A patent/IT1227791B/it active
- 1979-08-03 CA CA333,200A patent/CA1130290A/en not_active Expired
- 1979-08-03 PH PH22859A patent/PH24441A/en unknown
- 1979-08-03 AR AR277592A patent/AR220218A1/es active
- 1979-08-03 AU AU49547/79A patent/AU522843B2/en not_active Ceased
- 1979-08-06 GR GR59778A patent/GR69853B/el unknown
- 1979-08-06 ES ES483151A patent/ES483151A1/es not_active Expired
- 1979-08-06 IL IL57980A patent/IL57980A/xx unknown
- 1979-08-06 PT PT70029A patent/PT70029A/pt unknown
- 1979-08-06 FI FI792436A patent/FI65062C/fi not_active IP Right Cessation
- 1979-08-06 NZ NZ191227A patent/NZ191227A/xx unknown
- 1979-08-07 JP JP10115279A patent/JPS5524196A/ja active Pending
- 1979-08-07 EP EP79102847A patent/EP0008405B1/en not_active Expired
- 1979-08-07 DE DE7979102847T patent/DE2961141D1/de not_active Expired
- 1979-08-07 DK DK330579A patent/DK330579A/da not_active Application Discontinuation
- 1979-08-07 AT AT79102847T patent/ATE258T1/de not_active IP Right Cessation
- 1979-08-08 RO RO7998406A patent/RO78160A/ro unknown
- 1979-08-09 IE IE1534/79A patent/IE48618B1/en unknown
- 1979-08-09 HU HU79SI1715A patent/HU178110B/hu unknown
- 1979-08-09 CS CS795460A patent/CS226006B2/cs unknown
- 1979-08-09 NO NO792601A patent/NO153807C/no unknown
- 1979-08-09 DD DD79214893A patent/DD145532A5/de unknown
- 1979-08-10 MX MX798312U patent/MX5581E/es unknown
- 1979-08-10 BG BG044609A patent/BG32714A3/xx unknown
- 1979-08-10 PL PL21768479A patent/PL217684A1/xx unknown
- 1979-08-10 SU SU792798064A patent/SU860698A3/ru active

Also Published As

Publication number	Publication date
IE791534L (en)	1980-02-10
US4251660A (en)	1981-02-17
RO78160A (ro)	1982-02-01
FI65062B (fi)	1983-11-30
EP0008405A2 (en)	1980-03-05
DK330579A (da)	1980-02-11
PH24441A (en)	1990-06-25
PL217684A1 (cs)	1980-06-16
NO792601L (no)	1980-02-12
AR220218A1 (es)	1980-10-15
HU178110B (en)	1982-03-28
GR69853B (cs)	1982-07-19
ZA793308B (en)	1980-09-24
NO153807B (no)	1986-02-17
DD145532A5 (de)	1980-12-17
IT7924894A0 (it)	1979-08-02
IN152421B (cs)	1984-01-07
CS226006B2 (en)	1984-03-19
EP0008405B1 (en)	1981-09-30
AU522843B2 (en)	1982-07-01
NO153807C (no)	1986-05-28
EP0008405A3 (en)	1980-04-30
FI65062C (fi)	1984-03-12
SU860698A3 (ru)	1981-08-30
ES483151A1 (es)	1980-04-16
DE2961141D1 (en)	1981-12-10
AU4954779A (en)	1980-02-14
IT1227791B (it)	1991-05-07
IE48618B1 (en)	1985-03-20
ATE258T1 (de)	1981-10-15
FI792436A7 (fi)	1980-02-11
PT70029A (en)	1979-09-01
NZ191227A (en)	1981-10-19
CA1130290A (en)	1982-08-24
IL57980A0 (en)	1979-12-30
MX5581E (es)	1983-10-26
JPS5524196A (en)	1980-02-21
IL57980A (en)	1984-08-31

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