BG34763A3 - Метод за получаване на виндезинов сулфат - Google Patents

Метод за получаване на виндезинов сулфат

Info

Publication number: BG34763A3
Authority: BG; Bulgaria
Prior art keywords: sulfate; vindezine; obtaining; vindesine; equivalent
Prior art date: 1978-10-10

Application number

BG045074A

Other languages

Bulgarian (bg)

English (en)

Inventor

Stanislaw Rolski

Original Assignee

Eli Lilly And Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-10-10

Filing date

1979-10-08

Publication date

1983-11-15

1979-10-08 Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company

1983-11-15 Publication of BG34763A3 publication Critical patent/BG34763A3/xx

Links

238000000034 method Methods 0.000 title abstract 2
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 title 1
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 4
WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
NDMPLJNOPCLANR-UHFFFAOYSA-N 3,4-dihydroxy-15-(4-hydroxy-18-methoxycarbonyl-5,18-seco-ibogamin-18-yl)-16-methoxy-1-methyl-6,7-didehydro-aspidospermidine-3-carboxylic acid methyl ester Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 NDMPLJNOPCLANR-UHFFFAOYSA-N 0.000 abstract 2
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
238000003756 stirring Methods 0.000 abstract 2
229960004355 vindesine Drugs 0.000 abstract 2
UGGWPQSBPIFKDZ-KOTLKJBCSA-N vindesine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(N)=O)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1N=C1[C]2C=CC=C1 UGGWPQSBPIFKDZ-KOTLKJBCSA-N 0.000 abstract 2
KABRXLINDSPGDF-UHFFFAOYSA-N 7-bromoisoquinoline Chemical compound C1=CN=CC2=CC(Br)=CC=C21 KABRXLINDSPGDF-UHFFFAOYSA-N 0.000 abstract 1
229960005212 vindesine sulfate Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Saccharide Compounds (AREA)

BG045074A 1978-10-10 1979-10-08 Метод за получаване на виндезинов сулфат BG34763A3 (bg)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US94959578A	1978-10-10	1978-10-10

Publications (1)

Publication Number	Publication Date
BG34763A3 true BG34763A3 (bg)	1983-11-15

Family

ID=25489302

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG045074A BG34763A3 (bg)	1978-10-10	1979-10-08	Метод за получаване на виндезинов сулфат

Country Status (32)

Country	Link
EP (1)	EP0009996B1 (da)
JP (1)	JPS5553295A (da)
KR (1)	KR850000150B1 (da)
AR (1)	AR225153A1 (da)
AT (1)	AT370422B (da)
AU (1)	AU525702B2 (da)
BE (1)	BE879213A (da)
BG (1)	BG34763A3 (da)
CA (1)	CA1114817A (da)
CH (2)	CH645120A5 (da)
CS (1)	CS235503B2 (da)
DD (1)	DD146461A5 (da)
DE (1)	DE2964913D1 (da)
DK (1)	DK146823C (da)
EG (1)	EG14140A (da)
ES (1)	ES484827A1 (da)
FI (1)	FI70223C (da)
FR (1)	FR2438659A1 (da)
GB (1)	GB2031893B (da)
GR (1)	GR72394B (da)
HU (1)	HU180744B (da)
IE (1)	IE48958B1 (da)
IL (1)	IL58390A (da)
LU (1)	LU81763A1 (da)
MY (1)	MY8500569A (da)
NZ (1)	NZ191744A (da)
PH (1)	PH16092A (da)
PL (1)	PL117678B1 (da)
PT (1)	PT70269A (da)
RO (1)	RO77380A (da)
YU (1)	YU241179A (da)
ZA (1)	ZA795268B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4558053A (en) *	1983-12-21	1985-12-10	Eli Lilly And Company	Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids
CN112592357B (zh) *	2020-12-22	2022-03-22	海南长春花药业有限公司	一种硫酸长春地辛的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL48685A (en) *	1975-01-09	1980-03-31	Lilly Co Eli	Amides of vincadioline and vinblastine
US4029663A (en) *	1975-07-10	1977-06-14	Eli Lilly And Company	Dimeric anhydro-vinca derivatives
GR69783B (da) *	1976-09-08	1982-07-07	Lilly Co Eli

1979
- 1979-10-02 AR AR278306A patent/AR225153A1/es active
- 1979-10-03 CS CS796720A patent/CS235503B2/cs unknown
- 1979-10-03 AU AU51427/79A patent/AU525702B2/en not_active Expired
- 1979-10-03 YU YU02411/79A patent/YU241179A/xx unknown
- 1979-10-03 FI FI793065A patent/FI70223C/fi not_active IP Right Cessation
- 1979-10-03 ZA ZA00795268A patent/ZA795268B/xx unknown
- 1979-10-03 NZ NZ191744A patent/NZ191744A/xx unknown
- 1979-10-03 PT PT70269A patent/PT70269A/pt unknown
- 1979-10-04 CA CA336,959A patent/CA1114817A/en not_active Expired
- 1979-10-04 JP JP12879579A patent/JPS5553295A/ja active Granted
- 1979-10-04 IL IL58390A patent/IL58390A/xx unknown
- 1979-10-05 BE BE1/9554A patent/BE879213A/fr not_active IP Right Cessation
- 1979-10-05 FR FR7924841A patent/FR2438659A1/fr active Granted
- 1979-10-05 PL PL1979218756A patent/PL117678B1/pl unknown
- 1979-10-06 RO RO7998873A patent/RO77380A/ro unknown
- 1979-10-08 GR GR60215A patent/GR72394B/el unknown
- 1979-10-08 CH CH904479A patent/CH645120A5/fr not_active IP Right Cessation
- 1979-10-08 LU LU81763A patent/LU81763A1/fr unknown
- 1979-10-08 BG BG045074A patent/BG34763A3/xx unknown
- 1979-10-08 CH CH691/84A patent/CH649301A5/fr not_active IP Right Cessation
- 1979-10-08 ES ES484827A patent/ES484827A1/es not_active Expired
- 1979-10-09 DE DE7979302152T patent/DE2964913D1/de not_active Expired
- 1979-10-09 HU HU79EI881A patent/HU180744B/hu unknown
- 1979-10-09 EG EG590/79A patent/EG14140A/xx active
- 1979-10-09 DK DK422979A patent/DK146823C/da not_active IP Right Cessation
- 1979-10-09 EP EP79302152A patent/EP0009996B1/en not_active Expired
- 1979-10-09 IE IE1914/79A patent/IE48958B1/en not_active IP Right Cessation
- 1979-10-09 GB GB7935062A patent/GB2031893B/en not_active Expired
- 1979-10-09 AT AT0658279A patent/AT370422B/de not_active IP Right Cessation
- 1979-10-10 KR KR7903467A patent/KR850000150B1/ko not_active Expired
- 1979-10-10 DD DD79216158A patent/DD146461A5/de unknown
1981
- 1981-02-03 PH PH25176A patent/PH16092A/en unknown
1985
- 1985-12-30 MY MY569/85A patent/MY8500569A/xx unknown

Also Published As

Publication number	Publication date
KR850000150B1 (ko)	1985-02-28
IL58390A (en)	1982-07-30
FI70223B (fi)	1986-02-28
CS235503B2 (en)	1985-05-15
CH645120A5 (fr)	1984-09-14
DK146823C (da)	1984-07-02
IE48958B1 (en)	1985-06-26
DK422979A (da)	1980-04-11
FR2438659A1 (fr)	1980-05-09
FI793065A7 (fi)	1980-04-11
ZA795268B (en)	1981-05-27
BE879213A (fr)	1980-04-08
GB2031893A (en)	1980-04-30
EG14140A (en)	1983-09-30
HU180744B (en)	1983-04-29
GB2031893B (en)	1983-03-30
FR2438659B1 (da)	1983-03-18
DK146823B (da)	1984-01-16
GR72394B (da)	1983-11-01
DD146461A5 (de)	1981-02-11
EP0009996B1 (en)	1983-02-23
JPS5553295A (en)	1980-04-18
CH649301A5 (fr)	1985-05-15
PH16092A (en)	1983-06-20
AT370422B (de)	1983-03-25
PT70269A (de)	1979-11-01
PL117678B1 (en)	1981-08-31
LU81763A1 (fr)	1980-01-24
RO77380A (ro)	1981-11-04
KR830001282A (ko)	1983-04-30
NZ191744A (en)	1981-05-29
JPS628119B2 (da)	1987-02-20
IE791914L (en)	1980-04-10
DE2964913D1 (en)	1983-03-31
EP0009996A1 (en)	1980-04-16
YU241179A (en)	1983-01-21
CA1114817A (en)	1981-12-22
AU525702B2 (en)	1982-11-25
ES484827A1 (es)	1980-10-01
PL218756A1 (da)	1980-06-16
FI70223C (fi)	1986-09-15
AR225153A1 (es)	1982-02-26
IL58390A0 (en)	1980-01-31
AU5142779A (en)	1980-04-17
ATA658279A (de)	1982-08-15
MY8500569A (en)	1985-12-31

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