BG40810A3 - Метод за получаване на алкални соли на 4-хидрокси- 2-метил-n-(2-пиридил)-2н-1,2-бензотиазин-3-карбоксамид - Google Patents

Метод за получаване на алкални соли на 4-хидрокси- 2-метил-n-(2-пиридил)-2н-1,2-бензотиазин-3-карбоксамид

Info

Publication number
BG40810A3
BG40810A3 BG065219A BG6521984A BG40810A3 BG 40810 A3 BG40810 A3 BG 40810A3 BG 065219 A BG065219 A BG 065219A BG 6521984 A BG6521984 A BG 6521984A BG 40810 A3 BG40810 A3 BG 40810A3
Authority
BG
Bulgaria
Prior art keywords
piroxicam
solvent
benzothiazine
carboxamide
pyridyl
Prior art date
Application number
BG065219A
Other languages
Bulgarian (bg)
English (en)
Inventor
Melvin Noseworthy
Original Assignee
Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware filed Critical Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware
Publication of BG40810A3 publication Critical patent/BG40810A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
BG065219A 1983-04-25 1984-04-24 Метод за получаване на алкални соли на 4-хидрокси- 2-метил-n-(2-пиридил)-2н-1,2-бензотиазин-3-карбоксамид BG40810A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48830383A 1983-04-25 1983-04-25

Publications (1)

Publication Number Publication Date
BG40810A3 true BG40810A3 (bg) 1987-02-16

Family

ID=23939186

Family Applications (1)

Application Number Title Priority Date Filing Date
BG065219A BG40810A3 (bg) 1983-04-25 1984-04-24 Метод за получаване на алкални соли на 4-хидрокси- 2-метил-n-(2-пиридил)-2н-1,2-бензотиазин-3-карбоксамид

Country Status (28)

Country Link
EP (1) EP0123520B1 (cs)
JP (1) JPS59205375A (cs)
KR (1) KR840008345A (cs)
AT (1) ATE36531T1 (cs)
AU (1) AU548451B2 (cs)
BG (1) BG40810A3 (cs)
CA (1) CA1213220A (cs)
CS (1) CS246078B2 (cs)
DD (1) DD219672A5 (cs)
DE (1) DE3473454D1 (cs)
DK (1) DK165168C (cs)
EG (1) EG17887A (cs)
ES (1) ES531866A0 (cs)
FI (1) FI82377C (cs)
GR (1) GR81938B (cs)
GT (1) GT198404085A (cs)
HU (1) HU194217B (cs)
IE (1) IE57327B1 (cs)
IL (1) IL71598A (cs)
MX (1) MX159889A (cs)
NO (1) NO165177C (cs)
NZ (1) NZ207930A (cs)
PH (1) PH18864A (cs)
PL (1) PL144064B1 (cs)
PT (1) PT78473B (cs)
RO (1) RO88420A (cs)
YU (1) YU44232B (cs)
ZA (1) ZA843013B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582831A (en) * 1984-11-16 1986-04-15 Pfizer Inc. Anti-inflammatory polymorphic monoethanolamine salt of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide compound, composition, and method of use therefor
HU200926B (en) * 1988-10-28 1990-09-28 Egyt Gyogyszervegyeszeti Gyar Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules
GB9212450D0 (en) * 1992-06-11 1992-07-22 Indena Spa New derivatives of non-steroidal anti-inflammatory,analgesic and/or antipyretic substances,their use and pharmaceutical formulations containing them
KR100446829B1 (ko) * 2002-02-20 2004-09-04 한국유나이티드제약 주식회사 가용화된 피록시캄을 함유한 확산형 정제의 조성물 및그의 제조방법
KR100791160B1 (ko) * 2006-05-30 2008-01-02 조선대학교산학협력단 멜록시캄의 에탄올아민염 및 이를 함유하는 약제학적조성물
JP2010083826A (ja) * 2008-10-01 2010-04-15 Nihon Generic Co Ltd オキシカム系化合物を含む固形製剤を製造する方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4434164A (en) * 1981-06-01 1984-02-28 Pfizer Inc. Crystalline benzothiazine dioxide salts
IN160683B (cs) * 1981-06-01 1987-07-25 Pfizer

Also Published As

Publication number Publication date
DE3473454D1 (en) 1988-09-22
IE57327B1 (en) 1992-07-29
PH18864A (en) 1985-10-21
CA1213220A (en) 1986-10-28
ES8505365A1 (es) 1985-05-16
FI841604A0 (fi) 1984-04-24
ATE36531T1 (de) 1988-09-15
NO165177B (no) 1990-10-01
DD219672A5 (de) 1985-03-13
NO165177C (no) 1991-01-09
FI841604L (fi) 1984-10-26
EP0123520B1 (en) 1988-08-17
DK204484D0 (da) 1984-04-24
JPH0251527B2 (cs) 1990-11-07
YU44232B (en) 1990-04-30
PT78473B (en) 1986-08-28
JPS59205375A (ja) 1984-11-20
CS246078B2 (en) 1986-10-16
PT78473A (en) 1984-05-01
KR840008345A (ko) 1984-12-14
AU548451B2 (en) 1985-12-12
MX159889A (es) 1989-09-27
AU2716084A (en) 1984-11-01
GR81938B (cs) 1984-12-12
ZA843013B (en) 1985-12-24
DK165168C (da) 1993-03-08
NO841611L (no) 1984-10-26
NZ207930A (en) 1986-09-10
FI82377C (fi) 1991-03-11
GT198404085A (es) 1985-10-16
PL144064B1 (en) 1988-04-30
FI82377B (fi) 1990-11-30
IE840982L (en) 1984-10-25
YU72484A (en) 1988-04-30
RO88420A (ro) 1986-01-30
DK204484A (da) 1984-10-26
EP0123520A1 (en) 1984-10-31
IL71598A (en) 1987-01-30
HU194217B (en) 1988-01-28
DK165168B (da) 1992-10-19
EG17887A (en) 1991-03-30
PL247378A1 (en) 1985-03-26
IL71598A0 (en) 1984-07-31
HUT34023A (en) 1985-01-28
ES531866A0 (es) 1985-05-16

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