BG60324B2 - New somatotropines - Google Patents

New somatotropines

Info

Publication number: BG60324B2
Authority: BG; Bulgaria
Prior art keywords: somatotropines; new; somatotropins; glutamine; medicine
Prior art date: 1988-08-29

Application number

BG092028A

Other languages

Bulgarian (bg)

English (en)

Inventor

Gwen Krivi

Michael Schlittler

Bernard Violand

Original Assignee

Monsanto Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-08-29

Filing date

1990-05-16

Publication date

1994-07-25

1990-05-16 Application filed by Monsanto Company filed Critical Monsanto Company

1994-07-25 Publication of BG60324B2 publication Critical patent/BG60324B2/xx

Links

102000018997 Growth Hormone Human genes 0.000 abstract 2
108010051696 Growth Hormone Proteins 0.000 abstract 2
DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
229960001230 asparagine Drugs 0.000 abstract 1
235000009582 asparagine Nutrition 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 1
239000000122 growth hormone Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Endocrinology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Reproductive Health (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

BG092028A 1988-08-29 1990-05-16 New somatotropines BG60324B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/237,358 US5089473A (en)	1988-08-29	1988-08-29	Somatotropin variants and their use
PCT/US1989/003641 WO1990002182A1 (fr)	1988-08-29	1989-08-28	Nouvelles somatotropines

Publications (1)

Publication Number	Publication Date
BG60324B2 true BG60324B2 (en)	1994-07-25

Family

ID=22893393

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG092028A BG60324B2 (en)	1988-08-29	1990-05-16	New somatotropines

Country Status (14)

Country	Link
US (1)	US5089473A (fr)
EP (2)	EP0363342A1 (fr)
JP (1)	JP2784232B2 (fr)
AU (1)	AU614879B2 (fr)
BG (1)	BG60324B2 (fr)
BR (1)	BR8907068A (fr)
CA (1)	CA1340122C (fr)
DE (1)	DE68906261T2 (fr)
ES (2)	ES2054096T3 (fr)
HU (1)	HUT54409A (fr)
IL (1)	IL91457A (fr)
NZ (1)	NZ230458A (fr)
WO (1)	WO1990002182A1 (fr)
ZA (1)	ZA896557B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5631227A (en) *	1985-09-18	1997-05-20	The Upjohn Company	Somatotropin analogs
US5130422A (en) *	1988-08-29	1992-07-14	Monsanto Company	Variant somatotropin-encoding DNA
IE912345A1 (en) *	1990-08-03	1992-02-12	Pharmacia Ab	Treatment of human lactation failure
US20020137890A1 (en) *	1997-03-31	2002-09-26	Genentech, Inc.	Secreted and transmembrane polypeptides and nucleic acids encoding the same
GB9823071D0 (en) *	1998-10-21	1998-12-16	Affibody Technology Ab	A method
US6238706B1 (en)	1999-05-06	2001-05-29	Grofish L.L.C.	Method of stimulating growth in aquatic animals using growth hormones
WO2004022593A2 (fr) *	2002-09-09	2004-03-18	Nautilus Biotech	Evolution rationnelle de cytokines pour une plus grande stabilite, les cytokines et molecules d'acide nucleique codant
US7998930B2 (en)	2004-11-04	2011-08-16	Hanall Biopharma Co., Ltd.	Modified growth hormones
US8592555B2 (en)	2008-08-11	2013-11-26	Emd Millipore Corporation	Immunoglobulin-binding proteins with improved specificity
SG195555A1 (en)	2008-12-24	2013-12-30	Emd Millipore Corp	Caustic stable chromatography ligands
US8680050B2 (en) *	2009-02-03	2014-03-25	Amunix Operating Inc.	Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
DK3178835T3 (da)	2009-02-03	2019-06-24	Amunix Pharmaceuticals Inc	Forlængede rekombinante polypeptider og sammensætninger omfattende samme
US8703717B2 (en)	2009-02-03	2014-04-22	Amunix Operating Inc.	Growth hormone polypeptides and methods of making and using same
US9849188B2 (en)	2009-06-08	2017-12-26	Amunix Operating Inc.	Growth hormone polypeptides and methods of making and using same
SG10201604559TA (en)	2011-06-08	2016-07-28	Emd Millipore Corp	Chromatography matrices including novel staphylococcus aureus protein a based ligands

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GR79124B (fr)	1982-12-22	1984-10-02	Genentech Inc
US5037806A (en) *	1985-02-22	1991-08-06	Monsanto Company	Biologically active method using somatotropins
ES8800957A1 (es)	1985-02-22	1987-12-01	Monsanto Co	Un metodo para la solubilizacion y renaturalizacion de proteina somatotropina
ATE57937T1 (de) *	1985-09-18	1990-11-15	Upjohn Co	Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung.
DK154487A (da)	1986-03-27	1987-12-21	Monsanto Co	Nucleinsyremolekyle med en g1ol sekvens og fremgangsmaade til fremstilling af et protein ved hjaelp af molekylet
ES2019874B3 (es) *	1986-10-08	1991-07-16	Upjohn Co	Bioactividad mejorada de somatotropina de mamiferos mediante desamidacion selectiva.
EP0355460B1 (fr) *	1988-08-24	2000-12-27	American Cyanamid Company	Stabilisation de somatotropines par modification du résidu cystéine en utilisant un site de mutagénèse dirigée ou par modification chimique

1988
- 1988-08-29 US US07/237,358 patent/US5089473A/en not_active Expired - Fee Related
1989
- 1989-08-28 AU AU43160/89A patent/AU614879B2/en not_active Ceased
- 1989-08-28 HU HU895593A patent/HUT54409A/hu unknown
- 1989-08-28 ES ES89910508T patent/ES2054096T3/es not_active Expired - Lifetime
- 1989-08-28 ES ES89870130T patent/ES2016069A4/es active Pending
- 1989-08-28 IL IL9145789A patent/IL91457A/en not_active IP Right Cessation
- 1989-08-28 EP EP89870130A patent/EP0363342A1/fr active Pending
- 1989-08-28 WO PCT/US1989/003641 patent/WO1990002182A1/fr not_active Ceased
- 1989-08-28 JP JP1509826A patent/JP2784232B2/ja not_active Expired - Lifetime
- 1989-08-28 ZA ZA896557A patent/ZA896557B/xx unknown
- 1989-08-28 EP EP89910508A patent/EP0403601B1/fr not_active Expired - Lifetime
- 1989-08-28 NZ NZ230458A patent/NZ230458A/xx unknown
- 1989-08-28 CA CA000609518A patent/CA1340122C/fr not_active Expired - Fee Related
- 1989-08-28 DE DE89910508T patent/DE68906261T2/de not_active Expired - Fee Related
- 1989-08-28 BR BR898907068A patent/BR8907068A/pt not_active Application Discontinuation
1990
- 1990-05-16 BG BG092028A patent/BG60324B2/xx unknown

Also Published As

Publication number	Publication date
JPH03501856A (ja)	1991-04-25
DE68906261T2 (de)	1993-11-11
ES2054096T3 (es)	1994-08-01
ES2016069A4 (es)	1990-10-16
CA1340122C (fr)	1998-11-10
EP0363342A1 (fr)	1990-04-11
DE68906261D1 (de)	1993-06-03
NZ230458A (en)	1991-11-26
AU4316089A (en)	1990-03-23
HUT54409A (en)	1991-02-28
IL91457A0 (en)	1990-04-29
US5089473A (en)	1992-02-18
IL91457A (en)	1994-04-12
BR8907068A (pt)	1990-10-02
EP0403601A1 (fr)	1990-12-27
JP2784232B2 (ja)	1998-08-06
EP0403601B1 (fr)	1993-04-28
WO1990002182A1 (fr)	1990-03-08
AU614879B2 (en)	1991-09-12
ZA896557B (en)	1990-08-29

Publication	Publication Date	Title
US5565427C1 (en)	2002-07-23	Stabilized factor viii preparations
SE8600202D0 (sv)	1986-01-17	Farmaceutisk komposition (ii)
DE3768536D1 (de)	1991-04-18	Infusionsnadel.
NO2002009I2 (no)	2004-10-11	Tiotropium
DE68912777D1 (de)	1994-03-10	Insulin-analoge.
DE58904077D1 (de)	1993-05-19	Infusionspumpe.
DK485588A (da)	1989-03-04	Doseringsform omfattende hurtig (laege)middellevering efterfulgt af langsom (laege)middellevering
ATE115148T1 (de)	1994-12-15	Gereinigtes follikel-stimulierendes hormon.
NO871684D0 (no)	1987-04-23	Stol.
PT84058A (pt)	1987-09-18	Seringa para injeccoes, para emprego para uma so vez
NO162056C (no)	1989-11-01	Innretning for medisinavlevering.
IT8722816A0 (it)	1987-11-30	Unita' pompante.
ES2016069A4 (es)	1990-10-16	Nuevas somatotropinas.
DE3678347D1 (de)	1991-05-02	Aal-wachstumshormon.
ATE59550T1 (de)	1991-01-15	Chlorpheniramine therapie.
FI893366L (fi)	1990-01-13	4-piperidylmetyl-2,3-dihydro-1h -isoindol- och 2,3,4,5-tetrahydro-1h-bensasepinderivat, deras framstaellning och terapeutiska anvaendning.
ES2104551T3 (es)	1997-10-16	Analogos terapeuticos de somatostatina.
ATE101519T1 (de)	1994-03-15	Verwendung von gestoden zur herstellung von arzneimitteln.
IT1237087B (it)	1993-05-18	N,n'-di-(trimetossibenzoil) piperazine 2-metossicarbonil sostituite, procedimento per preparare le stesse e composti terapeutici che le contengono.
ES279057U (es)	1985-02-01	Jeringuilla para inyecciones
IT208775Z2 (it)	1988-05-28	Siringa per l'anestesia intraligamentosa.
ZA84381B (en)	1985-02-27	Peristaltic pump,particularly for medical applications
LT2623B (lt)	1994-04-25	Pakeistu 1,3,4,9-tetrahidropiran(3,4-beta)indol-1-acto rugsciu arba ju farmaciskai priimtinu drusku gavimo budas
FI840223A7 (fi)	1985-07-20	Letkupumppu, varsinkin lääketieteelliseen käyttöön.
ES1005075Y (es)	1990-05-01	Mesa de billar articulada.