BG62169B1 - 3-(5-тетразолил-бензил)амино-пиперидинови производни, методи за получаването им и фармацевтични състави с тях, използвани κακτο при метод за лечение, така и за производство на лекарства с приложе- ние при лечение на състояния, в които тахикинините са посредници - Google Patents

3-(5-тетразолил-бензил)амино-пиперидинови производни, методи за получаването им и фармацевтични състави с тях, използвани κακτο при метод за лечение, така и за производство на лекарства с приложе- ние при лечение на състояния, в които тахикинините са посредници Download PDF

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Publication number
BG62169B1
BG62169B1 BG100487A BG10048796A BG62169B1 BG 62169 B1 BG62169 B1 BG 62169B1 BG 100487 A BG100487 A BG 100487A BG 10048796 A BG10048796 A BG 10048796A BG 62169 B1 BG62169 B1 BG 62169B1
Authority
BG
Bulgaria
Prior art keywords
methoxy
tetrazol
phenyl
formula
title compound
Prior art date
Application number
BG100487A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100487A (bg
Inventor
Duncan R. Armour
Brian Evans
David Middlemiss
Alan Naylor
Neil A. Pegg
Maria V. Vinader
Gerard M. Giblin
Tania Hubbard
Michael M. Hann
Xiao-Qing Lewell
Stephen P. Watson
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939319606A external-priority patent/GB9319606D0/en
Priority claimed from GB9326583A external-priority patent/GB9326583D0/en
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of BG100487A publication Critical patent/BG100487A/bg
Publication of BG62169B1 publication Critical patent/BG62169B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
BG100487A 1993-09-22 1996-04-09 3-(5-тетразолил-бензил)амино-пиперидинови производни, методи за получаването им и фармацевтични състави с тях, използвани κακτο при метод за лечение, така и за производство на лекарства с приложе- ние при лечение на състояния, в които тахикинините са посредници BG62169B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939319606A GB9319606D0 (en) 1993-09-22 1993-09-22 Chemical compounds
GB9326583A GB9326583D0 (en) 1993-12-31 1993-12-31 Chemical compounds
PCT/EP1994/003129 WO1995008549A1 (en) 1993-09-22 1994-09-20 3-(5-tetrazolyl-benzyl)amino-piperidine derivatives and antagonists of tachykinins

Publications (2)

Publication Number Publication Date
BG100487A BG100487A (bg) 1996-12-31
BG62169B1 true BG62169B1 (bg) 1999-04-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BG100487A BG62169B1 (bg) 1993-09-22 1996-04-09 3-(5-тетразолил-бензил)амино-пиперидинови производни, методи за получаването им и фармацевтични състави с тях, използвани κακτο при метод за лечение, така и за производство на лекарства с приложе- ние при лечение на състояния, в които тахикинините са посредници

Country Status (29)

Country Link
US (2) US5703240A (is)
EP (1) EP0720609B1 (is)
JP (2) JP2865872B2 (is)
CN (1) CN1061041C (is)
AP (1) AP495A (is)
AT (1) ATE173255T1 (is)
AU (1) AU681190B2 (is)
BG (1) BG62169B1 (is)
CA (1) CA2172529A1 (is)
CO (1) CO4290298A1 (is)
CZ (1) CZ285479B6 (is)
DE (1) DE69414590T2 (is)
DK (1) DK0720609T3 (is)
ES (1) ES2123829T3 (is)
FI (1) FI961270A7 (is)
GR (1) GR3029354T3 (is)
HR (1) HRP940575B1 (is)
HU (1) HU217428B (is)
IL (1) IL111002A (is)
IS (1) IS4208A (is)
NO (1) NO307830B1 (is)
NZ (1) NZ273614A (is)
OA (1) OA10576A (is)
PE (1) PE18295A1 (is)
PL (1) PL179585B1 (is)
SI (1) SI0720609T1 (is)
SK (1) SK280901B6 (is)
UA (1) UA44711C2 (is)
WO (1) WO1995008549A1 (is)

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ES2123829T3 (es) 1999-01-16
EP0720609B1 (en) 1998-11-11
HU217428B (hu) 2000-01-28
EP0720609A1 (en) 1996-07-10
AP495A (en) 1996-05-28
UA44711C2 (uk) 2002-03-15
SK280901B6 (sk) 2000-09-12
DE69414590D1 (de) 1998-12-17
CN1061041C (zh) 2001-01-24
NO307830B1 (no) 2000-06-05
CO4290298A1 (es) 1996-04-17
FI961270A7 (fi) 1996-05-03
SI0720609T1 (en) 1999-02-28
US5843966A (en) 1998-12-01
OA10576A (en) 2002-06-03
PE18295A1 (es) 1995-07-27
AU7697494A (en) 1995-04-10
JPH11106341A (ja) 1999-04-20
PL313619A1 (en) 1996-07-08
AU681190B2 (en) 1997-08-21
HK1004219A1 (en) 1998-11-20
CZ285479B6 (cs) 1999-08-11
HRP940575A2 (en) 1997-02-28
JP2865872B2 (ja) 1999-03-08
AP9400671A0 (en) 1994-10-31
CA2172529A1 (en) 1995-03-30
ATE173255T1 (de) 1998-11-15
CZ83096A3 (en) 1996-09-11
CN1135218A (zh) 1996-11-06
DK0720609T3 (da) 1999-07-26
WO1995008549A1 (en) 1995-03-30
FI961270A0 (fi) 1996-03-19
DE69414590T2 (de) 1999-04-15
BG100487A (bg) 1996-12-31
IL111002A0 (en) 1994-11-28
NO961156D0 (no) 1996-03-21
US5703240A (en) 1997-12-30
SK38396A3 (en) 1997-02-05
NO961156L (no) 1996-05-21
NZ273614A (en) 1997-09-22
IL111002A (en) 1998-09-24
HUT75648A (en) 1997-05-28
IS4208A (is) 1995-03-23
PL179585B1 (pl) 2000-09-29
HU9600722D0 (en) 1996-05-28
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