BG62272B1 - Използване на 4-аминопиридин в терапията на неврологичнизаболявания - Google Patents

Използване на 4-аминопиридин в терапията на неврологичнизаболявания Download PDF

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Publication number
BG62272B1
BG62272B1 BG99047A BG9904794A BG62272B1 BG 62272 B1 BG62272 B1 BG 62272B1 BG 99047 A BG99047 A BG 99047A BG 9904794 A BG9904794 A BG 9904794A BG 62272 B1 BG62272 B1 BG 62272B1
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BG
Bulgaria
Prior art keywords
patients
infusion
effects
aminopyridine
patient
Prior art date
Application number
BG99047A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG99047A (bg
Inventor
Robert R. Hansebout
Andrew R. Blight
Original Assignee
Canadian Spinal Research Organization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canadian Spinal Research Organization filed Critical Canadian Spinal Research Organization
Publication of BG99047A publication Critical patent/BG99047A/bg
Publication of BG62272B1 publication Critical patent/BG62272B1/bg

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
BG99047A 1992-12-18 1994-09-16 Използване на 4-аминопиридин в терапията на неврологичнизаболявания BG62272B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002085785A CA2085785C (en) 1992-12-18 1992-12-18 The use of 4-aminopyridine in the treatment of a neurological condition
PCT/CA1993/000554 WO1994014439A1 (en) 1992-12-18 1993-12-20 The use of 4-aminopyridine in the treatment of a neurological condition

Publications (2)

Publication Number Publication Date
BG99047A BG99047A (bg) 1995-06-30
BG62272B1 true BG62272B1 (bg) 1999-07-30

Family

ID=4150879

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99047A BG62272B1 (bg) 1992-12-18 1994-09-16 Използване на 4-аминопиридин в терапията на неврологичнизаболявания

Country Status (19)

Country Link
US (1) US5545648A (de)
EP (1) EP0626848B1 (de)
JP (1) JP3474569B2 (de)
KR (1) KR100301415B1 (de)
AT (1) ATE241981T1 (de)
AU (1) AU676251B2 (de)
BG (1) BG62272B1 (de)
BR (1) BR9305909A (de)
CA (1) CA2085785C (de)
CZ (1) CZ284441B6 (de)
DE (1) DE69333014T2 (de)
ES (1) ES2199957T3 (de)
FI (1) FI943765L (de)
HU (1) HU219583B (de)
NO (2) NO308644B1 (de)
NZ (1) NZ258844A (de)
RU (1) RU2160590C2 (de)
SK (1) SK280922B6 (de)
WO (1) WO1994014439A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792743A (en) * 1995-04-19 1998-08-11 Acorda Therapeutics Method for promoting neural growth comprising administering a soluble neural cell adhesion molecule
JPH09315972A (ja) * 1996-03-22 1997-12-09 Chugai Pharmaceut Co Ltd 脊髄損傷治療剤
WO1999004705A1 (en) 1997-07-25 1999-02-04 Tsui Ban C H Devices, systems and methods for determining proper placement of epidural catheters
US7582680B1 (en) 1998-11-12 2009-09-01 Purdue Research Foundation Methods and compositions for treating mammalian spinal cord injuries
EP1152760B1 (de) * 1999-02-09 2007-03-28 UAB Research Foundation Verwendung von 4-aminopyridin zur behandlung von peripheren neuropathien
NO324322B1 (no) 2001-02-26 2007-09-24 Dynea Oy Anvendelse av herder samt fremgangsmate ved liming
CA2740056A1 (en) 2001-04-24 2002-11-21 Purdue Research Foundation Methods and compositions for treating mammalian nerve tissue injuries
US20040047843A1 (en) * 2002-02-12 2004-03-11 Uab Research Foundation Method for spinal cord reconnection
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
EP1567497B1 (de) * 2002-12-06 2009-09-23 Purdue Research Foundation Pyridine zur behandlung von verletztemsäugetiernervengewebe
JP4533590B2 (ja) * 2003-02-28 2010-09-01 ファイザー株式会社 脊髄損傷患者における疼痛又は痙性軽減用医薬組成物
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
US8007826B2 (en) * 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) * 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
BR112013019265A2 (pt) * 2011-01-28 2016-10-11 Acorda Therapeutics Inc uso de bloqueadores do canal de potássio no tratamento da paralisia cerebral
US8924325B1 (en) * 2011-02-08 2014-12-30 Lockheed Martin Corporation Computerized target hostility determination and countermeasure
TWI592156B (zh) * 2011-10-04 2017-07-21 艾可達醫療公司 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4508715A (en) * 1981-07-01 1985-04-02 University Of Georgia Research Foundation, Inc. Antagonism of central nervous system drugs by the administration of 4-aminopyridine alone or in combination with other drugs
JPH03505868A (ja) * 1988-04-08 1991-12-19 マサチユセツツ・インスチチユート・オブ・テクノロジー 神経性疾患を治療するための方法及び組成物
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases

Also Published As

Publication number Publication date
CZ284441B6 (cs) 1998-11-11
DE69333014D1 (de) 2003-07-10
SK280922B6 (sk) 2000-09-12
US5545648A (en) 1996-08-13
EP0626848A1 (de) 1994-12-07
WO1994014439A1 (en) 1994-07-07
NO308644B1 (no) 2000-10-09
KR950700062A (ko) 1995-01-16
NZ258844A (en) 1997-04-24
CZ225494A3 (en) 1995-03-15
HUT68171A (en) 1995-05-29
NO943049L (no) 1994-10-17
NO2012003I1 (no) 2012-02-13
DE69333014T2 (de) 2004-05-06
BG99047A (bg) 1995-06-30
SK96994A3 (en) 1995-04-12
HU9402647D0 (en) 1994-11-28
FI943765A7 (fi) 1994-10-14
JPH08504772A (ja) 1996-05-21
ATE241981T1 (de) 2003-06-15
CA2085785C (en) 2005-03-15
BR9305909A (pt) 1997-10-21
AU5691194A (en) 1994-07-19
NO943049D0 (no) 1994-08-17
EP0626848B1 (de) 2003-06-04
AU676251B2 (en) 1997-03-06
NO2012003I2 (no) 2013-02-18
RU94041207A (ru) 1996-06-20
HU219583B (hu) 2001-05-28
JP3474569B2 (ja) 2003-12-08
ES2199957T3 (es) 2004-03-01
FI943765A0 (fi) 1994-08-16
RU2160590C2 (ru) 2000-12-20
CA2085785A1 (en) 1994-06-19
FI943765L (fi) 1994-10-14
KR100301415B1 (ko) 2001-11-22

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