BG64625B1 - Бензотиено[3,2-c]пиридини, като алфа 2 - антагонисти - Google Patents

Бензотиено[3,2-c]пиридини, като алфа 2 - антагонисти Download PDF

Info

Publication number: BG64625B1
Authority: BG; Bulgaria
Prior art keywords: formula; alkyl; compound according; aryl; hydrogen
Prior art date: 1998-10-06

Application number

BG105331A

Other languages

Bulgarian (bg)

English (en)

Other versions

BG105331A (en

Inventor

Ludo Kennis

Serge Pieters

Francois BISCHOFF

Original Assignee

Janssen Pharmaceutica N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-06

Filing date

2001-03-12

Publication date

2005-09-30

2001-03-12 Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.

2001-11-30 Publication of BG105331A publication Critical patent/BG105331A/xx

2005-09-30 Publication of BG64625B1 publication Critical patent/BG64625B1/bg

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Psychology (AREA)
Hematology (AREA)
Obesity (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BG105331A 1998-10-06 2001-03-12 Бензотиено[3,2-c]пиридини, като алфа 2 - антагонисти BG64625B1 (bg)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP98203363		1998-10-06

Publications (2)

Publication Number	Publication Date
BG105331A BG105331A (en)	2001-11-30
BG64625B1 true BG64625B1 (bg)	2005-09-30

Family

ID=8234188

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG105331A BG64625B1 (bg)	1998-10-06	2001-03-12	Бензотиено[3,2-c]пиридини, като алфа 2 - антагонисти

Country Status (27)

Country	Link
US (2)	US6426350B1 (id)
EP (1)	EP1117667B1 (id)
JP (1)	JP4580555B2 (id)
KR (1)	KR20010071828A (id)
CN (1)	CN1158287C (id)
AR (1)	AR023678A1 (id)
AT (1)	ATE363485T1 (id)
AU (1)	AU760226B2 (id)
BG (1)	BG64625B1 (id)
BR (1)	BR9913110A (id)
CA (1)	CA2346084C (id)
CZ (1)	CZ20011103A3 (id)
DE (1)	DE69936219T2 (id)
EE (1)	EE04835B1 (id)
ES (1)	ES2288025T3 (id)
HU (1)	HUP0103612A3 (id)
ID (1)	ID28280A (id)
IL (2)	IL142442A0 (id)
NO (1)	NO20011309L (id)
NZ (1)	NZ509911A (id)
PL (1)	PL347184A1 (id)
RU (1)	RU2222542C2 (id)
SK (1)	SK4312001A3 (id)
TR (1)	TR200100954T2 (id)
TW (1)	TWI251595B (id)
UA (1)	UA70334C2 (id)
WO (1)	WO2000020422A1 (id)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003219029B2 (en) *	2002-03-08	2008-09-11	Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V	Use of EGFR transactivation inhibitors in human cancer
AU2003219199A1 (en) *	2002-04-03	2003-10-13	Orion Corporation	Use of an alfa2-adrenoreceptor antagonist for cns-related diseases
AU2005233456A1 (en)	2004-04-12	2005-10-27	Taisho Pharmaceutical Co., Ltd.	Cyclic amine compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3752820A (en)	1972-03-20	1973-08-14	Colgate Palmolive Co	Substituted-1,2,3,4-tetrahydrobenzothieno(3,2-c)pyridine derivatives
FR2570701B1 (fr) *	1984-09-27	1987-05-22	Synthelabo	Derives de furo(3,2-c)pyridines, leur preparation et leur application en therapeutique
US4686226A (en) *	1985-09-03	1987-08-11	Merck & Co., Inc.	Substituted benzo[b]furo- and benzo[b]thieno quinolizines
EP0339959A3 (en)	1988-04-27	1991-03-20	Glaxo Group Limited	Lactam derivatives
US5100891A (en) *	1991-01-18	1992-03-31	Hoechst-Roussel Pharmaceuticals Inc.	Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds
GB9106179D0 (en) *	1991-03-22	1991-05-08	Sandoz Ltd	Improvements in or relating to organic compounds
ATE247114T1 (de) *	1994-09-12	2003-08-15	Lilly Co Eli	Serotonergische modulatoren
JP3274579B2 (ja) *	1995-01-12	2002-04-15	住友製薬株式会社	脳血管障害に伴う精神症候治療剤
UA52681C2 (uk)	1997-04-08	2003-01-15	Янссен Фармацевтика Н.В.	Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі

1999
- 1999-01-10 UA UA2001031998A patent/UA70334C2/uk unknown
- 1999-10-01 SK SK431-2001A patent/SK4312001A3/sk unknown
- 1999-10-01 EP EP99947469A patent/EP1117667B1/en not_active Expired - Lifetime
- 1999-10-01 BR BR9913110-2A patent/BR9913110A/pt not_active Application Discontinuation
- 1999-10-01 CZ CZ20011103A patent/CZ20011103A3/cs unknown
- 1999-10-01 KR KR1020017000400A patent/KR20010071828A/ko not_active Ceased
- 1999-10-01 PL PL99347184A patent/PL347184A1/xx not_active Application Discontinuation
- 1999-10-01 CA CA2346084A patent/CA2346084C/en not_active Expired - Fee Related
- 1999-10-01 ES ES99947469T patent/ES2288025T3/es not_active Expired - Lifetime
- 1999-10-01 DE DE69936219T patent/DE69936219T2/de not_active Expired - Lifetime
- 1999-10-01 ID IDW20010781A patent/ID28280A/id unknown
- 1999-10-01 WO PCT/EP1999/007418 patent/WO2000020422A1/en not_active Ceased
- 1999-10-01 US US09/806,432 patent/US6426350B1/en not_active Expired - Lifetime
- 1999-10-01 CN CNB998116777A patent/CN1158287C/zh not_active Expired - Fee Related
- 1999-10-01 NZ NZ509911A patent/NZ509911A/xx unknown
- 1999-10-01 TW TW088116899A patent/TWI251595B/zh not_active IP Right Cessation
- 1999-10-01 HU HU0103612A patent/HUP0103612A3/hu unknown
- 1999-10-01 RU RU2001111753/04A patent/RU2222542C2/ru not_active IP Right Cessation
- 1999-10-01 IL IL14244299A patent/IL142442A0/xx active IP Right Grant
- 1999-10-01 TR TR2001/00954T patent/TR200100954T2/xx unknown
- 1999-10-01 EE EEP200100206A patent/EE04835B1/xx not_active IP Right Cessation
- 1999-10-01 AU AU60899/99A patent/AU760226B2/en not_active Ceased
- 1999-10-01 AT AT99947469T patent/ATE363485T1/de not_active IP Right Cessation
- 1999-10-01 JP JP2000574534A patent/JP4580555B2/ja not_active Expired - Fee Related
- 1999-10-05 AR ARP990105039A patent/AR023678A1/es active IP Right Grant
2001
- 2001-03-12 BG BG105331A patent/BG64625B1/bg unknown
- 2001-03-15 NO NO20011309A patent/NO20011309L/no not_active Application Discontinuation
- 2001-04-04 IL IL142442A patent/IL142442A/en not_active IP Right Cessation
2002
- 2002-04-16 US US10/123,338 patent/US6774129B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
HUP0103612A2 (hu)	2002-01-28
HK1039113A1 (en)	2002-04-12
ES2288025T3 (es)	2007-12-16
UA70334C2 (en)	2004-10-15
EE04835B1 (et)	2007-06-15
SK4312001A3 (en)	2001-12-03
DE69936219T2 (de)	2008-02-07
PL347184A1 (en)	2002-03-25
AU6089999A (en)	2000-04-26
DE69936219D1 (de)	2007-07-12
EP1117667A1 (en)	2001-07-25
US6426350B1 (en)	2002-07-30
JP4580555B2 (ja)	2010-11-17
IL142442A0 (en)	2002-03-10
US20020169178A1 (en)	2002-11-14
US6774129B2 (en)	2004-08-10
TR200100954T2 (tr)	2001-12-21
KR20010071828A (ko)	2001-07-31
JP2002526546A (ja)	2002-08-20
NO20011309D0 (no)	2001-03-15
AR023678A1 (es)	2002-09-04
RU2222542C2 (ru)	2004-01-27
BR9913110A (pt)	2001-05-08
IL142442A (en)	2006-10-05
CN1321159A (zh)	2001-11-07
NO20011309L (no)	2001-03-15
CZ20011103A3 (cs)	2001-12-12
ID28280A (id)	2001-05-10
AU760226B2 (en)	2003-05-08
EP1117667B1 (en)	2007-05-30
TWI251595B (en)	2006-03-21
NZ509911A (en)	2002-09-27
CN1158287C (zh)	2004-07-21
WO2000020422A1 (en)	2000-04-13
CA2346084A1 (en)	2000-04-13
BG105331A (en)	2001-11-30
EE200100206A (et)	2002-06-17
HUP0103612A3 (en)	2003-03-28
CA2346084C (en)	2010-01-26
ATE363485T1 (de)	2007-06-15

Publication	Publication Date	Title
EP1019408B1 (en)	2004-06-30	1,2,3,4-TETRAHYDRO-BENZOFURO[3,2-c]PYRIDINE DERIVATIVES
RU2230744C2 (ru)	2004-06-20	Трициклические δ3-пиперидины, способы их получения и фармацевтическая композиция на их основе
BG64871B1 (bg)	2006-07-31	Трициклични делта 3-пиперидини, като лекарства
JP4580555B2 (ja)	2010-11-17	α２アンタゴニストとしてのベンゾチエノ［３，２−ｃ］ピリジン類
EA003606B1 (ru)	2003-06-26	1,5-ПЕНТАНДИИЛЗАМЕЩЕННЫЕ 1,2,3,4-ТЕТРАГИДРОБЕНЗО (ФУРО, АЗО И ТИО) [3,2-c] ПИРИДИНОВЫЕ ПРОИЗВОДНЫЕ В КАЧЕСТВЕ α-АНТАГОНИСТОВ
MXPA01003514A (en)	2001-12-04	BENZOTHIENO[3,2-c]PYRIDINES AS&agr;2
HK1039113B (en)	2007-07-20	Benzothieno[3,2-c]pyridines as alpha2 antagonists
HK1038009B (en)	2004-12-24	Tricyclic delta3-piperidines as pharmaceuticals
MXPA01006353A (en)	2001-12-13	Benzisoxazoles and phenones as alpha 2-antagonists