BG94777A - Метод за произвеждане на нечовешки трансгенетични животни чрез въвеждане на екзогенна днк в соматични и зародишни клетки на животните - Google Patents

Метод за произвеждане на нечовешки трансгенетични животни чрез въвеждане на екзогенна днк в соматични и зародишни клетки на животните

Info

Publication number
BG94777A
BG94777A BG094777A BG9477791A BG94777A BG 94777 A BG94777 A BG 94777A BG 094777 A BG094777 A BG 094777A BG 9477791 A BG9477791 A BG 9477791A BG 94777 A BG94777 A BG 94777A
Authority
BG
Bulgaria
Prior art keywords
animals
transgenetic
germ cells
exogenous dna
human
Prior art date
Application number
BG094777A
Other languages
English (en)
Other versions
BG61041B1 (bg
Inventor
Corrado Spadafora
Original Assignee
Consiglio Nazionale Delle Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Delle Ricerche filed Critical Consiglio Nazionale Delle Ricerche
Publication of BG94777A publication Critical patent/BG94777A/bg
Publication of BG61041B1 publication Critical patent/BG61041B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Animal Husbandry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Методът е приложим в генното инженерство и биотехнологията. С него се създава възможност за изучаване генната регулация за химични и терапевтични цели и при развъждането на животни. Създават се трансгенетични животни, при които трайно е интегрирана информация, произхождаща от друга генетична система, чужда за генома на индивида. По метода екзогенна днк се вкарва в соматични и зародишни клетки, като предварително се модифицира по известните техники за рекомбинантни днк, след което се вкарва в сперматозоиздите на животните, които ще се модифицират и вследствие на това яйцеклетките се оплождат. 6 претенции
BG94777A 1989-01-10 1991-07-08 Метод за произвеждане на нечовешки трансгенетични животни чрез въвеждане на екзогенна днк в соматични и зародишни клетки на жи- вотните BG61041B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8919050A IT1228210B (it) 1989-01-10 1989-01-10 Procedimento per la introduzione di dna esogeno nelle cellule somatiche e germinali di animali.
PCT/EP1990/000032 WO1990008192A1 (en) 1989-01-10 1990-01-08 Process for the introduction of exogenous dna in somatic and germ animal cells

Publications (2)

Publication Number Publication Date
BG94777A true BG94777A (bg) 1993-12-24
BG61041B1 BG61041B1 (bg) 1996-09-30

Family

ID=11154128

Family Applications (1)

Application Number Title Priority Date Filing Date
BG94777A BG61041B1 (bg) 1989-01-10 1991-07-08 Метод за произвеждане на нечовешки трансгенетични животни чрез въвеждане на екзогенна днк в соматични и зародишни клетки на жи- вотните

Country Status (19)

Country Link
EP (1) EP0453458B1 (bg)
JP (1) JPH04504352A (bg)
AT (1) ATE121458T1 (bg)
AU (1) AU643672B2 (bg)
BG (1) BG61041B1 (bg)
BR (1) BR9007015A (bg)
CA (1) CA2045138A1 (bg)
DE (1) DE69018813T2 (bg)
DK (1) DK0453458T3 (bg)
ES (1) ES2074560T3 (bg)
FI (1) FI913266A0 (bg)
GR (1) GR900100012A (bg)
HU (1) HUT58818A (bg)
IE (1) IE67617B1 (bg)
IL (1) IL93024A (bg)
IT (1) IT1228210B (bg)
NO (1) NO912621L (bg)
PL (1) PL162962B1 (bg)
WO (1) WO1990008192A1 (bg)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92529A0 (en) * 1989-12-03 1990-08-31 Yissum Res Dev Co Generation of transgenic vertebrates by employing transformed sperm cells via artificial insemination
AU2146092A (en) * 1992-05-28 1993-12-30 Scientific Dimensions Usa, Inc. Transgenic animal production with biolistically transformed spermatozoa
JPH10304790A (ja) * 1995-09-29 1998-11-17 Hoechst Japan Ltd トランスジェニック動物の作成方法
US6734338B1 (en) 1997-11-14 2004-05-11 Cedars-Sinai Medical Center Transfection, storage and transfer of male germ cells for generation of transgenic species and genetic therapies
ATE426036T1 (de) 1997-11-14 2009-04-15 Cedars Sinai Medical Center Transfektion und transfer nicht humaner mannlicher keimzellen zur generierung transgener nicht humaner saugetiere
US7294755B1 (en) 1997-11-14 2007-11-13 Cedars-Sinai Medical Center Genetic modification of male germ cells for generation of transgenic species and genetic therapies
WO2000029602A1 (en) * 1998-11-13 2000-05-25 Cedars-Sinai Medical Center Transfection of male germ cells for generation of selectable transgenic stem cells
JP2003525581A (ja) * 1998-11-13 2003-09-02 セダーシナイ メディカル センター 脊椎動物精巣の細胞減失（ｄｅｐｏｐｕｌａｔｉｎｇ）方法およびトランスジェニック種の作製方法
JP3694734B2 (ja) * 2000-02-24 2005-09-14 国立大学法人京都大学 トランスジェニック動物の作製方法、トランスジェニック動物
US7053187B2 (en) 2000-03-28 2006-05-30 Gioagri Corporation Sperm-specific monoclonal antibody, mAbC
US7067308B1 (en) 2000-03-28 2006-06-27 Bioagri Corporation Vector for genetically modifying non-human animals

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3636991A1 (de) * 1986-03-03 1987-09-24 Transgene Gmbh Verfahren zur uebertragung organischer und/oder anorganischer substanzen auf ei- und/oder somazellen von tieren sowie entsprechende zusammensetzungen

Also Published As

Publication number Publication date
FI913266A7 (fi) 1991-07-05
WO1990008192A1 (en) 1990-07-26
IT8919050A0 (it) 1989-01-10
GR900100012A (el) 1991-06-07
DE69018813T2 (de) 1995-08-17
JPH04504352A (ja) 1992-08-06
BR9007015A (pt) 1991-11-12
IL93024A (en) 1995-08-31
BG61041B1 (bg) 1996-09-30
AU4810790A (en) 1990-08-13
IL93024A0 (en) 1990-11-05
AU643672B2 (en) 1993-11-25
ATE121458T1 (de) 1995-05-15
IE900085L (en) 1990-07-10
HUT58818A (en) 1992-03-30
DK0453458T3 (da) 1995-06-26
PL162962B1 (pl) 1994-01-31
FI913266A0 (fi) 1991-07-05
EP0453458A1 (en) 1991-10-30
NO912621D0 (no) 1991-07-04
IE67617B1 (en) 1996-04-17
ES2074560T3 (es) 1995-09-16
DE69018813D1 (de) 1995-05-24
IT1228210B (it) 1991-06-05
EP0453458B1 (en) 1995-04-19
NO912621L (no) 1991-08-28
CA2045138A1 (en) 1990-07-11

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