BR0010495A - Derivado da imidazodiazepina - Google Patents

Derivado da imidazodiazepina

Info

Publication number
BR0010495A
BR0010495A BR0010495-7A BR0010495A BR0010495A BR 0010495 A BR0010495 A BR 0010495A BR 0010495 A BR0010495 A BR 0010495A BR 0010495 A BR0010495 A BR 0010495A
Authority
BR
Brazil
Prior art keywords
imidazodiazepine
derived
compound
midazo
benzodiazepin
Prior art date
Application number
BR0010495-7A
Other languages
English (en)
Inventor
Francois Jenck
Fabienne Hoffmann-Emery
Walter Hunkeler
James Richard Martin
Andrews Leight
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR0010495A publication Critical patent/BR0010495A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Patente de Invenção: "DERIVADO DA IMIDAZODIAZEPINA". A presente invenção refere-se ao composto 7-cloro-3-(5-dimetilaminometil-[1,2,4]oxadiazol-3-il)-5-metil-4,5-diidro-i midazo[1,5-a][1,4]benzodiazepin-6-ona (I) e ao uso do composto de fórmula (I) para a fabricação de medicamentos para serem usados como medicamentos ansiolíticos e/ou anticonvulsivos e/ou indutores do sono não-sedativos.
BR0010495-7A 1999-05-12 2000-05-05 Derivado da imidazodiazepina BR0010495A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99109513 1999-05-12
PCT/EP2000/004034 WO2000069858A1 (en) 1999-05-12 2000-05-05 Imidazodiazepine derivative

Publications (1)

Publication Number Publication Date
BR0010495A true BR0010495A (pt) 2002-02-13

Family

ID=8238165

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0010495-7A BR0010495A (pt) 1999-05-12 2000-05-05 Derivado da imidazodiazepina

Country Status (17)

Country Link
US (1) US6391873B1 (pt)
EP (1) EP1178990B1 (pt)
JP (1) JP3706307B2 (pt)
KR (1) KR100451610B1 (pt)
CN (1) CN1164590C (pt)
AR (1) AR023884A1 (pt)
AT (1) ATE231865T1 (pt)
AU (1) AU769666B2 (pt)
BR (1) BR0010495A (pt)
CA (1) CA2372040C (pt)
DE (1) DE60001313T2 (pt)
DK (1) DK1178990T3 (pt)
ES (1) ES2189759T3 (pt)
MX (1) MXPA01011449A (pt)
TR (1) TR200103237T2 (pt)
WO (1) WO2000069858A1 (pt)
ZA (1) ZA200108913B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5180077B2 (ja) 2006-08-11 2013-04-10 パナソニック株式会社 複数ドライブ装置の遅延対策と省電力制御を行う記録再生装置
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
WO2009024324A2 (en) * 2007-08-20 2009-02-26 Evotec Neurosciences Gmbh Treatment of sleep disorders
WO2009024325A2 (en) * 2007-08-20 2009-02-26 Evotec Neurosciences Gmbh Treatment of sleep disorders
JP5345637B2 (ja) * 2008-01-22 2013-11-20 イーライ リリー アンド カンパニー κ選択的オピオイド受容体アンタゴニスト
CN107007559B (zh) * 2017-04-21 2020-05-15 浙江京新药业股份有限公司 一种稳定的口服药物组合物及其制备方法
CN109134471B (zh) * 2017-06-27 2020-05-15 浙江京新药业股份有限公司 一种苯并二氮杂*化合物的固态形式及其制备方法和应用
CN112778220B (zh) * 2019-11-02 2024-06-07 浙江京新药业股份有限公司 一种苯并二氮杂䓬二酮化合物d的制备方法及其中间体
CN113045574B (zh) * 2019-12-26 2024-06-07 浙江京新药业股份有限公司 二氮杂䓬衍生物的制备方法及其中间体
US12161622B2 (en) 2021-05-04 2024-12-10 Janssen Pharmaceuticals, Inc. Compositions and methods for the treatment of depression
WO2023170554A1 (en) 2022-03-07 2023-09-14 Janssen Pharmaceuticals, Inc. Compositions comprising aticaprant
WO2023170550A1 (en) 2022-03-07 2023-09-14 Janssen Pharmaceuticals, Inc. Polymorph forms of aticaprant for use in treating major depressive disorder

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2143246C (en) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines
PT801651E (pt) * 1995-01-06 2001-12-28 Hoffmann La Roche Hidroximetil-imidazodiazepinas e seus esteres

Also Published As

Publication number Publication date
DE60001313T2 (de) 2004-01-22
EP1178990A1 (en) 2002-02-13
CA2372040A1 (en) 2000-11-23
ATE231865T1 (de) 2003-02-15
AU769666B2 (en) 2004-01-29
CN1350538A (zh) 2002-05-22
CN1164590C (zh) 2004-09-01
JP3706307B2 (ja) 2005-10-12
KR20010112487A (ko) 2001-12-20
EP1178990B1 (en) 2003-01-29
KR100451610B1 (ko) 2004-10-06
WO2000069858A1 (en) 2000-11-23
AU5211400A (en) 2000-12-05
ES2189759T3 (es) 2003-07-16
ZA200108913B (en) 2003-03-26
TR200103237T2 (tr) 2002-04-22
DE60001313D1 (en) 2003-03-06
JP2002544277A (ja) 2002-12-24
DK1178990T3 (da) 2003-05-26
MXPA01011449A (es) 2002-06-04
US6391873B1 (en) 2002-05-21
AR023884A1 (es) 2002-09-04
CA2372040C (en) 2008-12-02

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O E 11 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]