BR0010707A - Métodos para purificação de proteìna usando extraçâo aquosa de duas fases - Google Patents
Métodos para purificação de proteìna usando extraçâo aquosa de duas fasesInfo
- Publication number
- BR0010707A BR0010707A BR0010707-7A BR0010707A BR0010707A BR 0010707 A BR0010707 A BR 0010707A BR 0010707 A BR0010707 A BR 0010707A BR 0010707 A BR0010707 A BR 0010707A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- phase extraction
- aqueous
- protein purification
- growth hormone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"MéTODOS PARA PURIFICAçãO DE PROTEìNA USANDO EXTRAçãO AQUOSA DE DUAS FASES". Métodos são providos nesta invenção para o isolamento de hormónio de crescimento humano, hormónio de crescimento antagonista, ou um homólogo de ambos de fonte biológica. Os métodos da invenção usam extrações multifase.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/307,549 US6437101B1 (en) | 1999-05-07 | 1999-05-07 | Methods for protein purification using aqueous two-phase extraction |
| PCT/US2000/012320 WO2000068260A1 (en) | 1999-05-07 | 2000-05-04 | Methods for protein purification using aqueous two-phase extraction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0010707A true BR0010707A (pt) | 2002-06-04 |
Family
ID=23190235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0010707-7A BR0010707A (pt) | 1999-05-07 | 2000-05-04 | Métodos para purificação de proteìna usando extraçâo aquosa de duas fases |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6437101B1 (pt) |
| EP (1) | EP1194445B1 (pt) |
| JP (1) | JP2002544139A (pt) |
| AT (1) | ATE384737T1 (pt) |
| AU (1) | AU777974B2 (pt) |
| BR (1) | BR0010707A (pt) |
| CA (1) | CA2372513A1 (pt) |
| DE (1) | DE60037886T2 (pt) |
| ES (1) | ES2303507T3 (pt) |
| IL (1) | IL146381A0 (pt) |
| MX (1) | MXPA01011356A (pt) |
| NZ (1) | NZ515381A (pt) |
| WO (1) | WO2000068260A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6966992B2 (en) * | 2001-03-19 | 2005-11-22 | Akzo Nobel Nv | Method of purification of molecules using unbranched terminal alkyldiols |
| KR20050071498A (ko) * | 2002-09-18 | 2005-07-07 | 상트르 오스피딸리에 드 루니버시떼 드 몬트리알 | 성장 호르몬 방출 호르몬 유사체 |
| EP1609800B1 (de) * | 2004-06-25 | 2007-11-14 | Kühni Ag | Verfahren zur Extraktion von biologischem Material |
| JP5043654B2 (ja) | 2004-06-29 | 2012-10-10 | アレス トレーディング ソシエテ アノニム | Il−18結合タンパク質の精製のための方法 |
| US20070048786A1 (en) * | 2005-09-01 | 2007-03-01 | Arnon Chait | Systems and methods for fractionation of protein mixtures |
| US20080070230A1 (en) * | 2006-06-12 | 2008-03-20 | Wyeth | Methods for reducing or preventing liquid-liquid phase separation in high concentration protein solutions |
| KR100836171B1 (ko) | 2007-01-19 | 2008-06-09 | 인하대학교 산학협력단 | 분배 향상 물질이 접합된 생물물질을 이용한 수성이상계추출법에서의 친화성 분리 방법 |
| DE102008013490A1 (de) * | 2008-03-10 | 2009-09-17 | Bayer Technology Services Gmbh | Verfahren zur Reinigung therapeutischer Proteine |
| EP2350113A4 (en) * | 2008-11-25 | 2013-01-02 | Ge Healthcare Bio Sciences Ab | FOR AN AQUEOUS TWO-PHASE EXTRACTION REINFORCED DEPOSITION PROCESS FOR CLEANING THERAPEUTIC PROTEINS |
| DE102011001743A1 (de) * | 2011-04-01 | 2012-10-04 | Technische Universität Dortmund | Verfahren zur Trennung/Reinigung von Biomolekühlen |
| CN102662015B (zh) * | 2012-04-12 | 2013-11-20 | 湖南师范大学 | 基于无机盐促相变分离纳米金的生物样品的净化方法 |
| US20130310554A1 (en) * | 2012-05-18 | 2013-11-21 | Hong Kong Baptist University | Aqueous Diphase Solvent System for Preparing High-Purity Polysaccharides |
| CN111249531B (zh) * | 2020-01-19 | 2022-03-22 | 巴斯特医药科技(常州)有限公司 | 一种高活性植物酶制备胶原蛋白支架的方法 |
| CN114957494A (zh) * | 2021-02-23 | 2022-08-30 | 江苏农牧科技职业学院 | 一种采用双水相萃取黄精多糖中蛋白质的工艺 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK144731C (da) | 1976-07-30 | 1982-10-18 | Nordisk Insulinlab | Fremgangsmaade til isolering af proteinhormoner stammende fra humant hypofysevaev |
| JPS5815989A (ja) * | 1981-06-12 | 1983-01-29 | Sanki Eng Kk | 生理活性蛋白質の精製方法 |
| DE3908422A1 (de) * | 1989-03-15 | 1990-09-20 | Forschungszentrum Juelich Gmbh | Verfahren zur extraktion von proteinen aus waessrigen biomassesuspensionen |
| US5151358A (en) | 1989-06-13 | 1992-09-29 | Genencor International, Inc. | Processes for the recovery of naturally produced chymosin |
| US5139943A (en) * | 1989-06-13 | 1992-08-18 | Genencor International, Inc. | Processes for the recovery of microbially produced chymosin |
| US5182369A (en) | 1990-02-28 | 1993-01-26 | Monsanto Company | Method for purifying somatotropin monomers |
| US5328841A (en) * | 1990-10-05 | 1994-07-12 | Genencor International, Inc. | Methods for isolating EG III cellulase component and EG III cellulase in polyethylene glycol using inorganic salt and polyethylene glycol |
| SE9003534D0 (sv) * | 1990-11-06 | 1990-11-06 | Kabigen Ab | A method for isolating and purifying peptides and proteins |
| US5407810A (en) | 1993-08-20 | 1995-04-18 | Genentech, Inc. | Aqueous multiple-phase isolation of polypeptide |
| US5734024A (en) * | 1996-04-19 | 1998-03-31 | Boris Y. Zaslavsky | Method for determining the biological activity of recombinant human growth hormone |
| GB0205898D0 (en) * | 2002-03-13 | 2002-04-24 | Pharmacia Ab | Treatment of type I diabetes mellitus |
-
1999
- 1999-05-07 US US09/307,549 patent/US6437101B1/en not_active Expired - Lifetime
-
2000
- 2000-05-04 IL IL14638100A patent/IL146381A0/xx unknown
- 2000-05-04 ES ES00928866T patent/ES2303507T3/es not_active Expired - Lifetime
- 2000-05-04 CA CA002372513A patent/CA2372513A1/en not_active Abandoned
- 2000-05-04 JP JP2000616234A patent/JP2002544139A/ja not_active Withdrawn
- 2000-05-04 MX MXPA01011356A patent/MXPA01011356A/es active IP Right Grant
- 2000-05-04 AU AU47036/00A patent/AU777974B2/en not_active Ceased
- 2000-05-04 NZ NZ515381A patent/NZ515381A/en unknown
- 2000-05-04 AT AT00928866T patent/ATE384737T1/de not_active IP Right Cessation
- 2000-05-04 WO PCT/US2000/012320 patent/WO2000068260A1/en not_active Ceased
- 2000-05-04 BR BR0010707-7A patent/BR0010707A/pt not_active IP Right Cessation
- 2000-05-04 EP EP00928866A patent/EP1194445B1/en not_active Expired - Lifetime
- 2000-05-04 DE DE60037886T patent/DE60037886T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1194445B1 (en) | 2008-01-23 |
| NZ515381A (en) | 2003-10-31 |
| US6437101B1 (en) | 2002-08-20 |
| MXPA01011356A (es) | 2003-08-20 |
| IL146381A0 (en) | 2002-07-25 |
| ES2303507T3 (es) | 2008-08-16 |
| EP1194445A1 (en) | 2002-04-10 |
| AU777974B2 (en) | 2004-11-04 |
| DE60037886D1 (de) | 2008-03-13 |
| DE60037886T2 (de) | 2009-01-22 |
| ATE384737T1 (de) | 2008-02-15 |
| AU4703600A (en) | 2000-11-21 |
| JP2002544139A (ja) | 2002-12-24 |
| WO2000068260A1 (en) | 2000-11-16 |
| CA2372513A1 (en) | 2000-11-16 |
| EP1194445A4 (en) | 2002-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 9A. E 10A. ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2077 DE 26/10/2010. |