BR0012748A - Análogo super-ativo do hormÈnio de lberação do hormõnio do crescimento porcino - Google Patents

Análogo super-ativo do hormÈnio de lberação do hormõnio do crescimento porcino

Info

Publication number
BR0012748A
BR0012748A BR0012748-5A BR0012748A BR0012748A BR 0012748 A BR0012748 A BR 0012748A BR 0012748 A BR0012748 A BR 0012748A BR 0012748 A BR0012748 A BR 0012748A
Authority
BR
Brazil
Prior art keywords
growth
hormone
growth hormone
animal
analog
Prior art date
Application number
BR0012748-5A
Other languages
English (en)
Inventor
Robert J Schwartz
Ruxandra Draghia-Akli
Original Assignee
Baylor College Of Medcine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Of Medcine filed Critical Baylor College Of Medcine
Publication of BR0012748A publication Critical patent/BR0012748A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"ANáLOGO SUPER-ATIVO DO HORMÈNIO DE LIBERAçãO DO HORMÈNIO DO CRESCIMENTO PORCINO". Crescimento inadequado devido a deficiências no hormónio do crescimento (GR) , no hormónio de liberação do hormónio do crescimento (GHRH) ou devido a doenças genéticas pode ser melhorado utilizando terapia com proteina recombinante com um GHRH análogo novo apresentando uma seq³ência da SEQ ID NO:1). Também está incluído: (1) um método de tratamento das deficiências relacionadas ao hormónio de crescimento associado com a via do hormónio do crescimento; (2) um método para tratamento das deficiências relacionadas ao hormónio do crescimento associado com doenças genéticas; (3) um método para melhorar o desempenho do crescimento em um animal; (4) um método para tratamento de um animal com uma doença de deficiência de crescimento; (5) um método para aumentar a eficiência de um animal utilizado para consumo; e (6) um método para intensificar o crescimento em um animal.
BR0012748-5A 1999-07-26 2000-07-24 Análogo super-ativo do hormÈnio de lberação do hormõnio do crescimento porcino BR0012748A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14562499P 1999-07-26 1999-07-26
PCT/US2000/020127 WO2001006988A2 (en) 1999-07-26 2000-07-24 Super-active porcine growth hormone releasing hormone analog

Publications (1)

Publication Number Publication Date
BR0012748A true BR0012748A (pt) 2003-06-10

Family

ID=22513900

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012748-5A BR0012748A (pt) 1999-07-26 2000-07-24 Análogo super-ativo do hormÈnio de lberação do hormõnio do crescimento porcino

Country Status (13)

Country Link
US (3) US6551996B1 (pt)
EP (1) EP1204321B1 (pt)
JP (1) JP4644402B2 (pt)
KR (1) KR20020047096A (pt)
CN (1) CN1635898A (pt)
AT (1) ATE309358T1 (pt)
AU (1) AU772752B2 (pt)
BR (1) BR0012748A (pt)
CA (1) CA2378943C (pt)
DE (1) DE60023906T2 (pt)
MX (1) MXPA02000938A (pt)
PL (1) PL366132A1 (pt)
WO (1) WO2001006988A2 (pt)

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US20030074679A1 (en) * 2000-12-12 2003-04-17 Schwartz Robert J. Administration of nucleic acid sequence to female animal to enhance growth in offspring
AR035671A1 (es) * 2000-12-12 2004-06-23 Advisys Inc Administracion de secuencia de acido nucleico a un animal hembra, para aumentar el crecimiento de la descendencia
WO2003023000A2 (en) * 2001-09-07 2003-03-20 Baylor College Of Medicine Linear dna fragments for gene expression
AU2002348417B9 (en) * 2001-10-26 2010-02-04 Baylor College Of Medicine A composition and method to alter lean body mass and bone properties in a subject
AR037778A1 (es) 2001-12-11 2004-12-01 Advisys Inc Suplementacion mediada por plasmido para el tratamiento de sujetos cronicamente enfermos
EP1499731B1 (en) * 2002-02-07 2011-05-25 Baylor College Of Medicine Modified pituitary gland development in offspring from expectant mother animals treated with growth hormone releasing hormone therapy
EP1513559A4 (en) * 2002-05-28 2006-01-18 Advisys Inc INCREASED DELIVERY OF A NUCLEIC ACID CONSTRUCTION IN VIVO WITH THE POLY-L-GLUTAMATE (PLG) SYSTEM
TW200403338A (en) * 2002-07-16 2004-03-01 Advisys Inc Codon optimized synthetic plasmids
EP1539959A2 (en) * 2002-09-18 2005-06-15 Centre Hospitalier de l'Université de Montréal (CHUM) Ghrh analogues
US20040204358A1 (en) * 2003-01-28 2004-10-14 Advisys, Inc. Reducing culling in herd animals growth hormone releasing hormone (GHRH)
CA2575926C (en) * 2003-08-04 2014-02-25 Advisys, Inc. Canine specific growth hormone releasing hormone
US7442673B2 (en) * 2003-08-15 2008-10-28 Crompton Corporation Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidazoles with epoxides as lubricant additives
CA2592891C (en) * 2003-12-31 2013-05-28 Advisys, Inc. Reducing arthritis and lameness in subjects by growth hormone releasing hormone (ghrh) supplementation
US20090005333A1 (en) * 2004-01-26 2009-01-01 Vgx Pharmaceuticlas, Inc. Reducing culling in herd animals growth hormone releasing hormone (ghrh)
US7846720B2 (en) * 2005-01-26 2010-12-07 Vgx Pharmaceuticals, Inc. Optimized high yield synthetic plasmids
US8889632B2 (en) 2007-01-31 2014-11-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
EP2508531B1 (en) 2007-03-28 2016-10-19 President and Fellows of Harvard College Stitched polypeptides
US8226468B2 (en) * 2008-11-13 2012-07-24 Igt Gaming system and method including points of symbol expansion
EP2421548A4 (en) * 2009-04-20 2012-09-26 Theratechnologies Inc USE OF (HEXENOYL TRANS-3) HGRF (1-44) NH2 AND SIMVASTATIN IN COMBINED TREATMENT
US20100267635A1 (en) * 2009-04-20 2010-10-21 Theratechonolgies Inc. Use of protease inhibitors and grf molecules in combination therapy
SI2603600T1 (sl) 2010-08-13 2019-04-30 Aileron Therapeutics, Inc. Peptidomimetični makrocikli
TW201806968A (zh) 2011-10-18 2018-03-01 艾利倫治療公司 擬肽巨環化合物
US8993316B2 (en) 2011-11-16 2015-03-31 Brian P. Hanley Methods and compositions for gene therapy and GHRH therapy
CN102516364B (zh) * 2011-12-26 2013-11-06 吉林农业大学 一种模拟猪生长激素样的活性肽及制备方法与应用
KR102112373B1 (ko) 2012-02-15 2020-05-18 에일러론 테라퓨틱스 인코포레이티드 펩티드모방체 마크로사이클
HK1205454A1 (en) 2012-02-15 2015-12-18 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
WO2013190520A2 (en) 2012-06-22 2013-12-27 The General Hospital Corporation Gh-releasing agents in the treatment of vascular stenosis and associated conditions
WO2014071241A1 (en) 2012-11-01 2014-05-08 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
BR112017005598A2 (pt) 2014-09-24 2017-12-12 Aileron Therapeutics Inc macrociclos peptidomiméticos e usos dos mesmos
WO2016154058A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
MX2018012716A (es) 2016-04-19 2019-02-11 Griffon Pharmaceuticals Inc Peptidos bioactivos pegilados y usos de los mismos.
CN112724260B (zh) * 2021-01-15 2021-11-30 安徽中起生物科技有限公司 一种脂质体包封的重组兽用促生长蛋白及其制备方法和应用
CN113582881B (zh) * 2021-07-29 2022-10-11 浙江新码生物医药有限公司 一种非天然氨基酸及其应用、包含其的重组蛋白以及重组蛋白偶联物

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Also Published As

Publication number Publication date
PL366132A1 (en) 2005-01-24
EP1204321B1 (en) 2005-11-09
US6551996B1 (en) 2003-04-22
AU772752B2 (en) 2004-05-06
CA2378943C (en) 2012-09-18
EP1204321A4 (en) 2002-11-06
JP2003517294A (ja) 2003-05-27
DE60023906T2 (de) 2006-07-20
DE60023906D1 (de) 2005-12-15
US7166461B2 (en) 2007-01-23
US20030129172A1 (en) 2003-07-10
KR20020047096A (ko) 2002-06-21
WO2001006988A3 (en) 2001-08-09
CN1635898A (zh) 2005-07-06
CA2378943A1 (en) 2001-02-01
WO2001006988A2 (en) 2001-02-01
ATE309358T1 (de) 2005-11-15
MXPA02000938A (es) 2004-03-19
EP1204321A2 (en) 2002-05-15
JP4644402B2 (ja) 2011-03-02
US20030148948A1 (en) 2003-08-07
AU6607800A (en) 2001-02-13

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT. CL. A01N 43/04, A61K 31/70, C12N 5/00, C12N 5/02, C12N 15/00, C12N 15/09, C12N 15/63, C12N 15/70, C12N 15/74 C12N 15/85, C12N 15/87, C07H 21/02, C07H 21/04.

Ipc: A61K 38/18 (2006.01), A61K 48/00 (2006.01), C12N 1

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: CONFORME ARTIGO 10O DA RESOLUCAO 124/06, CABE SER ARQUIVADO REFERENTE AO NAO RECOLHIMENTO DA 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2138 DE 27/12/2011.