BR0014573A - Fragmento de ácido nucléico isolado, polipeptìdeo, gene quimérico, célula hospedeira, célula hospedeira transformada, método de alteração do nìvel de expressão de uma proteìna cis- preniltransferase vegetal em células hospedeiras, método de obtenção de um fragmento de ácido nucléico e produto - Google Patents

Fragmento de ácido nucléico isolado, polipeptìdeo, gene quimérico, célula hospedeira, célula hospedeira transformada, método de alteração do nìvel de expressão de uma proteìna cis- preniltransferase vegetal em células hospedeiras, método de obtenção de um fragmento de ácido nucléico e produto

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Publication number
BR0014573A
BR0014573A BR0014573-4A BR0014573A BR0014573A BR 0014573 A BR0014573 A BR 0014573A BR 0014573 A BR0014573 A BR 0014573A BR 0014573 A BR0014573 A BR 0014573A
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BR
Brazil
Prior art keywords
host cell
nucleic acid
acid fragment
altering
polypeptide
Prior art date
Application number
BR0014573-4A
Other languages
English (en)
Inventor
Chris Coldren
Dennis Flint
David L Hallahan
Hong Wang
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of BR0014573A publication Critical patent/BR0014573A/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1085Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

"FRAGMENTO DE áCIDO NUCLéICO ISOLADO, POLIPEPTìDEO, GENE QUIMéRICO, CéLULA HOSPEDEIRA, CéLULA HOSPEDEIRA TRANSFORMADA, MéTODO DE ALTERAçãO DO NìVEL DE EXPRESSãO DE UMA PROTEìNA CIS-PRENILTRANSFERASE VEGETAL EM CéLULAS HOSPEDEIRAS, MéTODO DE OBTENçãO DE UM FRAGMENTO DE áCIDO NUCLéICO E PRODUTO". A presente invenção refere-se a fragmentos de ácidos nucléicos codificadores de proteínas vegetais que são homólogas as cispreniltransferases UPP sintase da bactéria Micrococcus luteus ou Dedol-PP sintase da levedura Saccharomyces cerevisiae. Mais especificamente, a presente invenção refere-se a homólogos de cis-preniltransferase de trigo, uva, soja, arroz, margarida africana, látex de seringueira e calêndula.
BR0014573-4A 1999-09-21 2000-09-21 Fragmento de ácido nucléico isolado, polipeptìdeo, gene quimérico, célula hospedeira, célula hospedeira transformada, método de alteração do nìvel de expressão de uma proteìna cis- preniltransferase vegetal em células hospedeiras, método de obtenção de um fragmento de ácido nucléico e produto BR0014573A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15504699P 1999-09-21 1999-09-21
PCT/US2000/025856 WO2001021650A2 (en) 1999-09-21 2000-09-21 Cis-prenyltransferases from plants

Publications (1)

Publication Number Publication Date
BR0014573A true BR0014573A (pt) 2002-06-18

Family

ID=22553920

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0014573-4A BR0014573A (pt) 1999-09-21 2000-09-21 Fragmento de ácido nucléico isolado, polipeptìdeo, gene quimérico, célula hospedeira, célula hospedeira transformada, método de alteração do nìvel de expressão de uma proteìna cis- preniltransferase vegetal em células hospedeiras, método de obtenção de um fragmento de ácido nucléico e produto

Country Status (7)

Country Link
US (3) US6645747B1 (pt)
EP (1) EP1214338A2 (pt)
KR (1) KR20020040810A (pt)
AU (1) AU7598200A (pt)
BR (1) BR0014573A (pt)
CA (1) CA2381020A1 (pt)
WO (1) WO2001021650A2 (pt)

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JP2003527077A (ja) * 1999-04-15 2003-09-16 カルジーン エルエルシー トコフェロール合成に関与するタンパク質の核酸配列
US6872815B1 (en) 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
AR030124A1 (es) 2000-08-07 2003-08-13 Monsanto Technology Llc Genes de la via del fosfato de metil-d-eritritol
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
DE60230608D1 (de) 2001-05-09 2009-02-12 Monsanto Technology Llc Tyra-gene und ihre verwendung
WO2003016482A2 (en) 2001-08-17 2003-02-27 Monsanto Technology Llc Methyltransferase genes and uses thereof
WO2003034812A2 (en) 2001-10-25 2003-05-01 Monsanto Technology Llc Aromatic methyltransferases and uses thereof
AU2002336866B8 (en) * 2001-11-01 2009-04-23 The University Of British Columbia Diagnosis and treatment of infectious diseases through indel-differentiated proteins
US7112717B2 (en) 2002-03-19 2006-09-26 Monsanto Technology Llc Homogentisate prenyl transferase gene (HPT2) from arabidopsis and uses thereof
EP1546334A4 (en) 2002-08-05 2007-01-03 Monsanto Technology Llc GENES ASSOCIATED WITH TOCOPHEROL BIOSYNTHESIS AND USES THEREOF
AU2003295489A1 (en) 2002-11-13 2004-06-03 E.I. Du Pont De Nemours And Company Cis-prenyltransferases from the rubber-producing plants russian dandelion (taraxacum kok-saghyz) and sunflower (helianthus annus)
US8426194B2 (en) 2003-01-21 2013-04-23 Ptc Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating VEGF expression
US8460864B2 (en) 2003-01-21 2013-06-11 Ptc Therapeutics, Inc. Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same
US9068234B2 (en) * 2003-01-21 2015-06-30 Ptc Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating gene expression
WO2004106531A1 (en) * 2003-05-22 2004-12-09 E.I. Dupont De Nemours And Company Method for manipulating growth, yield, and architecture in plants
WO2005049868A1 (en) * 2003-11-17 2005-06-02 Pct Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating her2 expression
US9018449B2 (en) * 2004-03-10 2015-04-28 The United States of America, represented by The Secretary of Agiculture Transformation methods for Guayule using Agrobacterium and reduced light to slow metabolism and enhance recovery
CN101023181A (zh) 2004-05-21 2007-08-22 加利福尼亚大学董事会 提高类异戊二烯化合物的产生的方法
BRPI0513837B1 (pt) 2004-07-27 2021-10-13 The Regents Of The University Of California Célula hospedeira saccharomyces cerevisiae geneticamente modificada; composição compreendendo a mesma e método para aumentar a produção de isoprenoides
WO2007005604A2 (en) 2005-07-05 2007-01-11 The Regents Of The University Of California Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
US20090288226A1 (en) * 2005-11-21 2009-11-19 Hallahan David L Method for manipulating growth, yield, and architecture in plants
DK2066778T3 (en) 2006-09-26 2016-04-18 Amyris Biotechnologies Inc PREPARATION OF ISOPRENOIDS AND ISOPRENOID PRECURSORS
US8283115B1 (en) 2007-06-20 2012-10-09 Ptc Therapeutics, Inc. Methods of screening for compounds for treating muscular dystrophy using UTRN mRNA translation regulation
US8283116B1 (en) 2007-06-22 2012-10-09 Ptc Therapeutics, Inc. Methods of screening for compounds for treating spinal muscular atrophy using SMN mRNA translation regulation
US8618355B2 (en) 2008-03-17 2013-12-31 National Research Council Of Canada Aromatic prenyltransferase from hop
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EP2268675B1 (en) 2008-04-14 2013-11-27 Bridgestone Corporation Processes for recovering rubber from natural rubber latex
AR078502A1 (es) 2009-10-02 2011-11-09 Pioneer Hi Bred Int Regulacion hacia abajo de acc (acido 1-aminociclopropano-1-carboxilico) sintasa para el rendimiento mejorado de plantas
MY174987A (en) * 2011-04-29 2020-05-31 Univ Sains Malaysia Undecaprenyl pyrophosphate synthase from the plant of hevea brasiliensis
WO2012148835A1 (en) 2011-04-29 2012-11-01 Pioneer Hi-Bred International, Inc. Down-regulation of a homeodomain-leucine zipper i-class homeobox gene for improved plant performance
MY160195A (en) * 2011-05-12 2017-02-28 Univ Sains Malaysia Cis-prenyl transferase from the plant hevea brasiliensis
US12359004B2 (en) 2012-03-06 2025-07-15 Bridgestone Corporation Processes for the removal of rubber from non-Hevea plants
RU2017130331A (ru) 2012-03-06 2019-02-05 Бриджстоун Корпорейшн Способ выделения каучука из выдержанных брикетов и выдержанные брикеты, содержащие растительный материал гуаюлы
AU2013262725B2 (en) 2012-05-16 2016-10-06 Bridgestone Corporation Compositions containing purified non-Hevea rubber and related purification methods
AU2013277296B2 (en) 2012-06-18 2016-08-11 Bridgestone Corporation Methods for desolventization of bagasse
AU2013277335B2 (en) 2012-06-18 2016-08-11 Bridgestone Corporation Systems and methods for the management of waste associated with processing guayule shrubs to extract rubber
EP2861627B1 (en) 2012-06-18 2017-03-01 Bridgestone Corporation Methods for increasing the extractable rubber content of non-hevea plant matter
WO2015038707A1 (en) 2013-09-11 2015-03-19 Bridgestone Corporation Processes for the removal of rubber from tks plant matter
WO2016204503A1 (ko) * 2015-06-15 2016-12-22 아주대학교 산학협력단 재조합 미생물을 이용한 천연고무의 생산 방법
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
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Also Published As

Publication number Publication date
US6645747B1 (en) 2003-11-11
US7273737B2 (en) 2007-09-25
KR20020040810A (ko) 2002-05-30
EP1214338A2 (en) 2002-06-19
US7880058B2 (en) 2011-02-01
US20080096276A1 (en) 2008-04-24
US20040152158A1 (en) 2004-08-05
CA2381020A1 (en) 2001-03-29
WO2001021650A3 (en) 2001-12-13
WO2001021650A2 (en) 2001-03-29
AU7598200A (en) 2001-04-24

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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