BR0014656A - Agentes terapêuticos - Google Patents

Agentes terapêuticos

Info

Publication number: BR0014656A
Authority: BR; Brazil
Prior art keywords: therapeutic agents; pyridin; ylsulphonyl; ethylpiperazin; pyrazolo
Prior art date: 1999-10-11

Application number

BR0014656-0A

Other languages

English (en)

Portuguese (pt)

Inventor

Michael Leslie Hughes

Richard Anthony Storey

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-11

Filing date

2000-10-06

Publication date

2002-06-11

2000-10-06 Application filed by Pfizer filed Critical Pfizer

2002-06-11 Publication of BR0014656A publication Critical patent/BR0014656A/pt

Links

239000003814 drug Substances 0.000 title abstract 2
229940124597 therapeutic agent Drugs 0.000 title 1
QDPNAMRLQRQPMR-UHFFFAOYSA-N 3-ethyl-5-[5-(4-ethylpiperazin-1-yl)sulfonyl-2-(2-methoxyethoxy)pyridin-3-yl]-2-(pyridin-2-ylmethyl)-4h-pyrazolo[4,3-d]pyrimidin-7-one Chemical class C1CN(CC)CCN1S(=O)(=O)C1=CN=C(OCCOC)C(C=2NC(=O)C3=NN(CC=4N=CC=CC=4)C(CC)=C3N=2)=C1 QDPNAMRLQRQPMR-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical class CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Hospice & Palliative Care (AREA)
Nutrition Science (AREA)
Otolaryngology (AREA)
Gynecology & Obstetrics (AREA)
Ophthalmology & Optometry (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Separation Of Suspended Particles By Flocculating Agents (AREA)

BR0014656-0A 1999-10-11 2000-10-06 Agentes terapêuticos BR0014656A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9923968.3A GB9923968D0 (en)	1999-10-11	1999-10-11	Therapeutic agents
PCT/IB2000/001445 WO2001027101A2 (en)	1999-10-11	2000-10-06	Anhydrous salt

Publications (1)

Publication Number	Publication Date
BR0014656A true BR0014656A (pt)	2002-06-11

Family

ID=10862471

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR0014656-0A BR0014656A (pt)	1999-10-11	2000-10-06	Agentes terapêuticos

Country Status (17)

Country	Link
EP (1)	EP1220855B1 (de)
JP (1)	JP2003511446A (de)
AT (1)	ATE267203T1 (de)
AU (1)	AU7441100A (de)
BR (1)	BR0014656A (de)
CA (1)	CA2382937A1 (de)
CO (1)	CO5271692A1 (de)
DE (1)	DE60010914T2 (de)
DK (1)	DK1220855T3 (de)
ES (1)	ES2219395T3 (de)
GB (1)	GB9923968D0 (de)
PA (1)	PA8503701A1 (de)
PE (1)	PE20010674A1 (de)
PT (1)	PT1220855E (de)
SV (1)	SV2002000191A (de)
TN (1)	TNSN00196A1 (de)
WO (1)	WO2001027101A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002089808A1 (de) *	2001-05-09	2002-11-14	Bayer Healthcare Ag	Neue verwendung von 2-phenyl-substituierten imidazotriazinonen
GB0126417D0 (en) *	2001-11-02	2002-01-02	Pfizer Ltd	Crystal structure
DE10232113A1 (de)	2002-07-16	2004-01-29	Bayer Ag	Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
BRPI0409931A (pt) *	2003-05-01	2006-04-25	Pfizer	cristal de pde5, sua estrutura de cristal e seu em projeto de droga

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6723719B1 (en) *	1997-04-25	2004-04-20	Pfizer Inc	Pyrazolopyrimidinones which inhibit type 5 cyclic guanosine 3′,5′—monophosphate phosphodiesterase (cGMP PDE5) for the treatment of sexual dysfunction
RS50011B (sr) *	1998-04-20	2008-09-29	Pfizer Inc.,	Derivati piridin-3-karboksilne kiseline i njihova upotreba kao intermedijera

1999
- 1999-10-11 GB GBGB9923968.3A patent/GB9923968D0/en not_active Ceased
2000
- 2000-09-27 PA PA20008503701A patent/PA8503701A1/es unknown
- 2000-10-05 PE PE2000001054A patent/PE20010674A1/es not_active Application Discontinuation
- 2000-10-06 CA CA002382937A patent/CA2382937A1/en not_active Abandoned
- 2000-10-06 EP EP00962772A patent/EP1220855B1/de not_active Expired - Lifetime
- 2000-10-06 PT PT00962772T patent/PT1220855E/pt unknown
- 2000-10-06 AT AT00962772T patent/ATE267203T1/de not_active IP Right Cessation
- 2000-10-06 DK DK00962772T patent/DK1220855T3/da active
- 2000-10-06 AU AU74411/00A patent/AU7441100A/en not_active Abandoned
- 2000-10-06 ES ES00962772T patent/ES2219395T3/es not_active Expired - Lifetime
- 2000-10-06 JP JP2001530319A patent/JP2003511446A/ja active Pending
- 2000-10-06 WO PCT/IB2000/001445 patent/WO2001027101A2/en not_active Ceased
- 2000-10-06 BR BR0014656-0A patent/BR0014656A/pt not_active IP Right Cessation
- 2000-10-06 DE DE60010914T patent/DE60010914T2/de not_active Expired - Fee Related
- 2000-10-10 CO CO00077030A patent/CO5271692A1/es not_active Application Discontinuation
- 2000-10-10 SV SV2000000191A patent/SV2002000191A/es unknown
- 2000-10-10 TN TNTNSN00196A patent/TNSN00196A1/fr unknown

Also Published As

Publication number	Publication date
AU7441100A (en)	2001-04-23
PT1220855E (pt)	2004-08-31
SV2002000191A (es)	2002-01-23
ES2219395T3 (es)	2004-12-01
PE20010674A1 (es)	2001-06-27
DK1220855T3 (da)	2004-09-27
WO2001027101A2 (en)	2001-04-19
DE60010914D1 (de)	2004-06-24
CO5271692A1 (es)	2003-04-30
PA8503701A1 (es)	2001-10-10
GB9923968D0 (en)	1999-12-15
EP1220855B1 (de)	2004-05-19
CA2382937A1 (en)	2001-04-19
EP1220855A2 (de)	2002-07-10
ATE267203T1 (de)	2004-06-15
WO2001027101A3 (en)	2001-06-14
TNSN00196A1 (fr)	2005-11-10
JP2003511446A (ja)	2003-03-25
DE60010914T2 (de)	2004-10-28

Legal Events

Date	Code	Title	Description
2008-08-12	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 6A,7A E 8A ANUIDADE.
2009-03-03	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.

Publication	Publication Date	Title
YU6303A (sh)	2006-03-03	Nova heterociklična jedinjenja, njihovo dobijanje i njihova upotreba kao medikamenata, a naročito kao anti-bakterijskih agenasa
DE60204452D1 (de)	2005-07-07	Pyrazolo[1,5]pyridinderivate
MXPA03011039A (es)	2004-03-19	Nuevos compuestos heterociclicos, su preparacion y uso como medicamentos, particularmente como agentes anti-bacterianos.
WO1999064409A3 (de)	2000-03-02	Benzothiepin-1,1-dioxidderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
SE9904505D0 (sv)	1999-12-09	Novel compounds
IL185611A0 (en)	2008-01-06	Novel imidazo[1,5-a]pyridine derivatives, method for preparing same and pharmaceutical compositions containing same
DE60305113D1 (de)	2006-06-14	Borsäuresalze und deren Verwendung in der Bereitstellung von Medikamente für die Thrombosebehandlung
BR9812492A (pt)	2000-09-26	Composto, uso do mesmo, formulação farmacêutica, e, processos para o tratamento de uma doença cardiovascular, para o tratamento de uma vasoconstrição, e para a preparação de compostos
MY114944A (en)	2003-02-28	Propanolamine derivatives, processes for their preparation pharmaceuticals comprising these compounds, and their use
CA2298461A1 (en)	1999-03-04	Heterocyclic substituted 4-benzoyl-pyrazole as herbicides
SG145570A1 (en)	2008-09-29	4-æ7-halo-2-quino(xa-)linyloxy!phenoxy-propionic acid derivatives as antineoplastic agents
MXPA04005484A (es)	2004-12-06	Procedimiento de preparacion de derivados de equinocandina.
CO5271692A1 (es)	2003-04-30	Agentes terapeuticos
SE0102057D0 (sv)	2001-06-08	New Salts I
AU530678B2 (en)	1983-07-28	Phosphono-hydroxy-acetic acid
TR199801191T2 (xx)	1998-10-21	�o�ul ila� direnci mod�lat�rleri olarak kayna��k imidazol t�revleri.
SE0102058D0 (sv)	2001-06-08	New Salts II
MY113529A (en)	2002-03-30	New derivatives of imidazole n- benzyldioxole,processes for their preparation, their use as medicaments and pharmaceutical compositions containing them
AU2001244999A1 (en)	2001-10-23	Naphthamide neurokinin antagonists for use as medicaments
SE9803280D0 (sv)	1998-09-25	Novel compounds
UY26382A1 (es)	2001-05-31	Agentes terapéuticos
SE9803277D0 (sv)	1998-09-25	Novel compounds
ATE199557T1 (de)	2001-03-15	Calcium-komplex von (4r)-4-bis(carboxy- kappa.o)methyl amino-.kappa.n-6,9-bis (carboxy-