BR0015486A - Ligandos de neurofilina para tratamento de condições oculares - Google Patents

Ligandos de neurofilina para tratamento de condições oculares

Info

Publication number
BR0015486A
BR0015486A BR0015486-5A BR0015486A BR0015486A BR 0015486 A BR0015486 A BR 0015486A BR 0015486 A BR0015486 A BR 0015486A BR 0015486 A BR0015486 A BR 0015486A
Authority
BR
Brazil
Prior art keywords
ligands
neurophylline
eye conditions
treating eye
neurophilin
Prior art date
Application number
BR0015486-5A
Other languages
English (en)
Inventor
Iok-Hou Pang
Mark A Hellberg
Abdelmoula Namil
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of BR0015486A publication Critical patent/BR0015486A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Patente de Invenção: "LIGANDOS DE NEUROFILINA PARA TRATAMENTO DE CONDIçõES OCULARES". é revelado o uso de ligandos de neurofilina para tratamento de glaucoma e diminuição de IOP.
BR0015486-5A 1999-11-12 2000-10-24 Ligandos de neurofilina para tratamento de condições oculares BR0015486A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16513799P 1999-11-12 1999-11-12
PCT/US2000/029320 WO2001035948A2 (en) 1999-11-12 2000-10-24 Neurophilin ligands for treating ocular conditions

Publications (1)

Publication Number Publication Date
BR0015486A true BR0015486A (pt) 2002-07-02

Family

ID=22597584

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0015486-5A BR0015486A (pt) 1999-11-12 2000-10-24 Ligandos de neurofilina para tratamento de condições oculares

Country Status (16)

Country Link
US (1) US20060083774A1 (pt)
EP (1) EP1227859B1 (pt)
JP (1) JP2003514015A (pt)
AR (1) AR034103A1 (pt)
AT (1) ATE335524T1 (pt)
AU (1) AU784347B2 (pt)
BR (1) BR0015486A (pt)
CA (1) CA2386579A1 (pt)
CY (1) CY1106232T1 (pt)
DE (1) DE60029985T2 (pt)
DK (1) DK1227859T3 (pt)
ES (1) ES2269206T3 (pt)
HK (1) HK1046108B (pt)
PT (1) PT1227859E (pt)
TW (1) TW200511984A (pt)
WO (1) WO2001035948A2 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021178977A1 (en) * 2020-03-06 2021-09-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Compositions and methods for treating ocular disorders

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260059A (en) * 1989-04-14 1993-11-09 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University Treatment of open-angle glaucoma by modulation matrix metalloproteinases and their inhibitor
US5922773A (en) * 1992-12-04 1999-07-13 The Children's Medical Center Corp. Glaucoma treatment
US5798355A (en) * 1995-06-07 1998-08-25 Gpi Nil Holdings, Inc. Inhibitors of rotamase enzyme activity
US5710165A (en) * 1994-07-06 1998-01-20 Synthelabo Use of polyamine antagonists for the treatment of glaucoma
US5614547A (en) * 1995-06-07 1997-03-25 Guilford Pharmaceuticals Inc. Small molecule inhibitors of rotamase enzyme
US5696135A (en) * 1995-06-07 1997-12-09 Gpi Nil Holdings, Inc. Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth
US5859031A (en) * 1995-06-07 1999-01-12 Gpi Nil Holdings, Inc. Small molecule inhibitors of rotamase enzyme activity
US5856329A (en) * 1995-06-28 1999-01-05 Allergan Method of using (2-imidazolin-2-ylamino) quinoxalines in treating ocular neural injury
US5786378A (en) * 1996-09-25 1998-07-28 Gpi Nil Holdings, Inc. Heterocyclic thioesters
US5801187A (en) * 1996-09-25 1998-09-01 Gpi-Nil Holdings, Inc. Heterocyclic esters and amides
US5811434A (en) * 1996-11-13 1998-09-22 Vertex Pharmacueticals Incorporated Methods and compositions for stimulating neurite growth
US5780484A (en) * 1996-11-13 1998-07-14 Vertex Pharmaceuticals Incorporated Methods for stimulating neurite growth with piperidine compounds
US5840736A (en) * 1996-11-13 1998-11-24 Vertex Pharmaceuticals Incorporated Methods and compositions for stimulating neurite growth
US5721256A (en) * 1997-02-12 1998-02-24 Gpi Nil Holdings, Inc. Method of using neurotrophic sulfonamide compounds
US5846979A (en) * 1997-02-28 1998-12-08 Gpi Nil Holdings, Inc. N-oxides of heterocyclic esters, amides, thioesters, and ketones
US5877211A (en) * 1997-11-21 1999-03-02 Allergan EP2 receptor agonists as neuroprotective agents for the eye
DK1056454T3 (da) * 1998-02-23 2003-08-18 Fujisawa Pharmaceutical Co Anvendelse af makrolidforbindelser til behandling af glaukom
EP1105112A2 (en) * 1998-08-14 2001-06-13 GPI NIL Holdings, Inc. Compositions and uses for vision and memory disorders
US6399648B1 (en) * 1998-08-14 2002-06-04 Gpi Nil Holdings, Inc. N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders

Also Published As

Publication number Publication date
EP1227859B1 (en) 2006-08-09
CA2386579A1 (en) 2001-05-25
PT1227859E (pt) 2006-12-29
JP2003514015A (ja) 2003-04-15
AU784347B2 (en) 2006-03-16
DK1227859T3 (da) 2006-12-11
WO2001035948A2 (en) 2001-05-25
TW200511984A (en) 2005-04-01
US20060083774A1 (en) 2006-04-20
ATE335524T1 (de) 2006-09-15
AR034103A1 (es) 2004-02-04
WO2001035948A3 (en) 2002-01-17
DE60029985D1 (de) 2006-09-21
DE60029985T2 (de) 2007-02-01
ES2269206T3 (es) 2007-04-01
EP1227859A2 (en) 2002-08-07
HK1046108A1 (en) 2002-12-27
CY1106232T1 (el) 2011-06-08
AU1752201A (en) 2001-05-30
HK1046108B (en) 2007-01-05

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DE INT.CL: A61K 31/00

Ipc: A61K 31/444 (2009.01), A61K 31/40 (2009.01), A61P

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10(VIII), 13, 24 E 25 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.