ATE386520T1 - Kombination von riluzol und levodopa zur behandlung von morbus parkinson - Google Patents

Kombination von riluzol und levodopa zur behandlung von morbus parkinson

Info

Publication number: ATE386520T1
Authority: AT; Austria
Prior art keywords: combination; riluzole; levodopa; disease; parkinson
Prior art date: 1998-04-24

Application number

AT99915809T

Other languages

English (en)

Inventor

Veronique Blanchard-Bregeon

Assunta Imperato

Saliha Moussaoui

Marie-Carmen Obinu

Michel Reibaud

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-24

Filing date

1999-04-22

Publication date

2008-03-15

1999-04-22 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2008-03-15 Application granted granted Critical

2008-03-15 Publication of ATE386520T1 publication Critical patent/ATE386520T1/de

Links

WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 title abstract 2
WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 title abstract 2
208000018737 Parkinson disease Diseases 0.000 title abstract 2
FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 title abstract 2
229960004502 levodopa Drugs 0.000 title abstract 2
229960004181 riluzole Drugs 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Emergency Medicine (AREA)
Psychiatry (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
External Artificial Organs (AREA)

AT99915809T 1998-04-24 1999-04-22 Kombination von riluzol und levodopa zur behandlung von morbus parkinson ATE386520T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9805153A FR2777781B1 (fr)	1998-04-24	1998-04-24	Associations riluzole et l-dopa pour le traitement de la maladie de parkinson

Publications (1)

Publication Number	Publication Date
ATE386520T1 true ATE386520T1 (de)	2008-03-15

Family

ID=9525640

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99915809T ATE386520T1 (de)	1998-04-24	1999-04-22	Kombination von riluzol und levodopa zur behandlung von morbus parkinson

Country Status (22)

Country	Link
US (1)	US6387936B1 (de)
EP (1)	EP1071422B1 (de)
JP (1)	JP2002512963A (de)
KR (1)	KR100597170B1 (de)
AT (1)	ATE386520T1 (de)
AU (1)	AU768069B2 (de)
CA (1)	CA2329636C (de)
CY (1)	CY1110448T1 (de)
CZ (1)	CZ300825B6 (de)
DE (1)	DE69938179T2 (de)
DK (1)	DK1071422T3 (de)
ES (1)	ES2300141T3 (de)
FR (1)	FR2777781B1 (de)
HU (1)	HU228902B1 (de)
IL (1)	IL139164A (de)
NO (1)	NO329032B1 (de)
PT (1)	PT1071422E (de)
RU (1)	RU2225204C2 (de)
SK (1)	SK285531B6 (de)
UA (1)	UA70319C2 (de)
WO (1)	WO1999055336A1 (de)
ZA (1)	ZA200005758B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2786101B1 (fr) *	1998-11-24	2002-07-05	Aventis Laboratoire	Utilisation de la nicergoline dans le traitement de la spasticite
US6872739B1 (en) *	1999-06-04	2005-03-29	Vereniging Voor Christelijk Wetenshappelikjk Onderwijs	Use of riluzole for the treatment of multiple sclerosis
GB0007193D0 (en) *	2000-03-25	2000-05-17	Univ Manchester	Treatment of movrmrnt disorders
US8158149B2 (en) *	2004-05-12	2012-04-17	Chelsea Therapeutics, Inc.	Threo-DOPS controlled release formulation
WO2004100929A1 (en)	2003-05-12	2004-11-25	Synergia Pharma, Inc.	Threo-dops controlled release formulation
WO2005025561A1 (en) *	2003-09-04	2005-03-24	Synergia Pharma, Inc.	Compositions and methods for orthostatic intolerance
WO2005112906A2 (en) *	2004-05-21	2005-12-01	Duke University	Method for augmenting the effects of serotonin reuptake inhibitors
SE0401842D0 (sv) *	2004-07-12	2004-07-12	Dizlin Medical Design Ab	Infusion and injection solution of levodopa
WO2006060120A2 (en) *	2004-11-07	2006-06-08	Guilford F Timothy	Liposomal formulation for oral administration of glutathione (reduced)
GB0504103D0 (en) *	2005-02-28	2005-04-06	Syngenta Ltd	Novel method
US20070148238A1 (en) *	2005-06-23	2007-06-28	Spherics, Inc.	Dosage forms for movement disorder treatment
US20080131492A1 (en) *	2006-06-23	2008-06-05	Spherics, Inc.	Dosage forms for movement disorder treatment
DK1948155T3 (da) *	2006-06-28	2012-07-02	Chelsea Therapeutics Inc	Farmaceutiske præparater omfattende droxidopa
EP2063867A2 (de) *	2006-12-22	2009-06-03	Combinatorx, Incorporated	Pharmazeutische zusammensetzungen zur behandlung von morbus parkinson und damit verbundenen leiden
US8008285B2 (en) *	2007-03-09	2011-08-30	Chelsea Therapeutics, Inc.	Droxidopa and pharmaceutical composition thereof for the treatment of fibromyalgia
AU2008248382B2 (en) *	2007-05-07	2013-07-18	Chelsea Therapeutics, Inc.	Droxidopa and pharmaceutical composition thereof for the treatment of mood disorders, sleep disorders, or attention deficit disorders
EP2320892A2 (de) *	2008-06-30	2011-05-18	Novartis AG	Kombinationsprodukte
CA2742841A1 (en) *	2008-11-06	2010-05-14	Biotie Therapies, Inc.	Treatment of restless leg syndrome and sleep disorders
EP2228054A1 (de) *	2009-03-13	2010-09-15	ITALFARMACO S.p.A.	Wässrige Riluzol-Suspensionen
ES2703255T3 (es)	2010-10-22	2019-03-07	Univ Duke	Formulaciones de liberación lenta de 5-hidroxitriptófano como un complemento para terapias pro-serotoninérgicas
JP5880913B2 (ja)	2011-05-17	2016-03-09	三郎佐古田	パーキンソン病の体幹症状（姿勢反射異常）の治療剤
US9463186B2 (en)	2013-04-15	2016-10-11	Northwestern University	Treatment for dopaminergic disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2700117B1 (fr) *	1993-01-07	1995-02-03	Rhone Poulenc Rorer Sa	Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens.
RU2057529C1 (ru) *	1994-05-30	1996-04-10	Алексей Михайлович Коршунов	Способ лечения синдрома паркинсонизма

1998
- 1998-04-24 FR FR9805153A patent/FR2777781B1/fr not_active Expired - Fee Related
1999
- 1999-04-22 KR KR1020007011786A patent/KR100597170B1/ko not_active Expired - Fee Related
- 1999-04-22 JP JP2000545534A patent/JP2002512963A/ja not_active Withdrawn
- 1999-04-22 EP EP99915809A patent/EP1071422B1/de not_active Expired - Lifetime
- 1999-04-22 PT PT99915809T patent/PT1071422E/pt unknown
- 1999-04-22 SK SK1588-2000A patent/SK285531B6/sk not_active IP Right Cessation
- 1999-04-22 HU HU0101645A patent/HU228902B1/hu not_active IP Right Cessation
- 1999-04-22 CA CA002329636A patent/CA2329636C/fr not_active Expired - Fee Related
- 1999-04-22 DK DK99915809T patent/DK1071422T3/da active
- 1999-04-22 WO PCT/FR1999/000953 patent/WO1999055336A1/fr not_active Ceased
- 1999-04-22 AU AU34255/99A patent/AU768069B2/en not_active Ceased
- 1999-04-22 DE DE69938179T patent/DE69938179T2/de not_active Expired - Lifetime
- 1999-04-22 RU RU2000129121/15A patent/RU2225204C2/ru not_active IP Right Cessation
- 1999-04-22 ES ES99915809T patent/ES2300141T3/es not_active Expired - Lifetime
- 1999-04-22 IL IL13916499A patent/IL139164A/xx not_active IP Right Cessation
- 1999-04-22 CZ CZ20003908A patent/CZ300825B6/cs not_active IP Right Cessation
- 1999-04-22 UA UA2000105983A patent/UA70319C2/uk unknown
- 1999-04-22 AT AT99915809T patent/ATE386520T1/de active
2000
- 2000-10-17 ZA ZA200005758A patent/ZA200005758B/en unknown
- 2000-10-20 NO NO20005290A patent/NO329032B1/no not_active IP Right Cessation
- 2000-10-24 US US09/694,860 patent/US6387936B1/en not_active Expired - Lifetime
2008
- 2008-04-24 CY CY20081100457T patent/CY1110448T1/el unknown

Also Published As

Publication number	Publication date
AU768069B2 (en)	2003-12-04
IL139164A0 (en)	2001-11-25
NO329032B1 (no)	2010-08-02
FR2777781B1 (fr)	2004-04-09
CA2329636C (fr)	2009-09-08
JP2002512963A (ja)	2002-05-08
ES2300141T3 (es)	2008-06-01
RU2225204C2 (ru)	2004-03-10
FR2777781A1 (fr)	1999-10-29
NO20005290D0 (no)	2000-10-20
DE69938179T2 (de)	2009-02-12
EP1071422A1 (de)	2001-01-31
IL139164A (en)	2005-12-18
SK15882000A3 (sk)	2001-04-09
AU3425599A (en)	1999-11-16
WO1999055336A1 (fr)	1999-11-04
CY1110448T1 (el)	2015-04-29
DE69938179D1 (de)	2008-04-03
DK1071422T3 (da)	2008-06-16
HUP0101645A3 (en)	2002-10-28
US6387936B1 (en)	2002-05-14
CA2329636A1 (fr)	1999-11-04
EP1071422B1 (de)	2008-02-20
ZA200005758B (en)	2002-01-17
NO20005290L (no)	2000-10-20
SK285531B6 (sk)	2007-03-01
CZ300825B6 (cs)	2009-08-19
KR100597170B1 (ko)	2006-07-05
UA70319C2 (en)	2004-10-15
HU228902B1 (en)	2013-06-28
CZ20003908A3 (cs)	2001-02-14
PT1071422E (pt)	2008-05-05
HUP0101645A2 (hu)	2001-09-28
KR20010042960A (ko)	2001-05-25

Legal Events

Date

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Title

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2008-10-15

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Publication	Publication Date	Title
ATE386520T1 (de)	2008-03-15	Kombination von riluzol und levodopa zur behandlung von morbus parkinson
GB0108592D0 (en)	2001-05-23	Therapeutic agents
ATE385794T1 (de)	2008-03-15	Benzothiazolderivate zur behandlung von alzheimer und parkinson
DE69829921D1 (de)	2005-06-02	Vorrichtung zur Behandlung von Körpergewebe
DE59610964D1 (de)	2004-05-06	Anordnung zur elektro-thermischen Behandlung des menschlichen oder tierischen Körpers
ATE342728T1 (de)	2006-11-15	Zubereitung zur behandlung von einer neurologischen erkrankung
GB0223040D0 (en)	2002-11-13	Therapeutic compounds
ATE334668T1 (de)	2006-08-15	Pharmazeutische zusammensetzung zur behandlung von neurologischen und neuropsychiatrischen erkrankungen
PL310475A1 (en)	1995-12-11	Application of anticonvulsants in treating neuro-aids diseases
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FI952953L (fi)	1995-12-18	Aineita metabolisten luustosairauksien hoitamiseen
DE69214647D1 (de)	1996-11-21	Verwendung von atipamezol zur behandlung der männlichen sexuellen impotenz
ATE323486T1 (de)	2006-05-15	Verwendung des riluzols oder dessen salzen zur phophylaxe und behandlung der adrenoleukodystrophie
DK1133297T3 (da)	2003-11-24	Ny terapeutisk anvendelse af 1,6-dimethyl-8beta-hydroxymethyl-10alpha-methoxyergolin
RU97111440A (ru)	1999-07-20	Препарат для лечения отморожений
ATE316373T1 (de)	2006-02-15	Conagenin zur behandlung von ulzerativer kolitis und/oder morbus crohn
DE69822628D1 (de)	2004-04-29	Zur vorbeugung oder behandlung von östrogenabhängigen krankheiten nützliche pyrrolo[2.1.5-cd]indolizin-derivate