BR0015938A - Uso de antagonistas beta-adrenoceptores para a fabricação de um medicamento para o tratamento de desordens da retina externa - Google Patents
Uso de antagonistas beta-adrenoceptores para a fabricação de um medicamento para o tratamento de desordens da retina externaInfo
- Publication number
- BR0015938A BR0015938A BR0015938-7A BR0015938A BR0015938A BR 0015938 A BR0015938 A BR 0015938A BR 0015938 A BR0015938 A BR 0015938A BR 0015938 A BR0015938 A BR 0015938A
- Authority
- BR
- Brazil
- Prior art keywords
- disorders
- beta
- drug
- manufacture
- treatment
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title abstract 2
- 102000015005 beta-adrenergic receptor activity proteins Human genes 0.000 title abstract 2
- 108040006818 beta-adrenergic receptor activity proteins Proteins 0.000 title abstract 2
- 210000001525 retina Anatomy 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
"USO DE ANTAGONISTAS BETA-ADRENOCEPTORES PARA A FABRICAçãO DE UM MEDICAMENTO PARA O TRATAMENTO DE DESORDENS DA RETINA EXTERNA". A invenção refere-se ao uso de antagonistas beta-adrenoceptores para a fabricação de um medicamento para o tratamento de desordens da retina externa.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16799399P | 1999-11-30 | 1999-11-30 | |
| PCT/US2000/032575 WO2001043737A1 (en) | 1999-11-30 | 2000-11-29 | Use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0015938A true BR0015938A (pt) | 2002-08-27 |
Family
ID=22609644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0015938-7A BR0015938A (pt) | 1999-11-30 | 2000-11-29 | Uso de antagonistas beta-adrenoceptores para a fabricação de um medicamento para o tratamento de desordens da retina externa |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US7081482B2 (pt) |
| EP (1) | EP1244438B1 (pt) |
| JP (2) | JP4758581B2 (pt) |
| CN (1) | CN1245966C (pt) |
| AT (1) | ATE253905T1 (pt) |
| AU (1) | AU782524B2 (pt) |
| BR (1) | BR0015938A (pt) |
| CA (1) | CA2388728C (pt) |
| DE (1) | DE60006584T2 (pt) |
| DK (1) | DK1244438T3 (pt) |
| ES (1) | ES2210023T3 (pt) |
| HK (1) | HK1047695B (pt) |
| MX (1) | MXPA02005378A (pt) |
| PL (1) | PL214875B1 (pt) |
| PT (1) | PT1244438E (pt) |
| TR (1) | TR200302008T4 (pt) |
| WO (1) | WO2001043737A1 (pt) |
| ZA (1) | ZA200203133B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1245966C (zh) * | 1999-11-30 | 2006-03-22 | 爱尔康公司 | β-肾上腺素受体拮抗剂用于制备治疗外层视网膜疾病的药物的用途 |
| CN100413503C (zh) * | 2005-01-07 | 2008-08-27 | 冷文 | 一种复方眼药组合物 |
| WO2008080110A1 (en) * | 2006-12-21 | 2008-07-03 | Alcon, Inc. | Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor |
| CA2717825A1 (en) * | 2008-03-07 | 2009-09-11 | Sun Pharma Advanced Research Company Ltd. | Opthalmic composition |
| US10267796B2 (en) * | 2010-10-25 | 2019-04-23 | The Procter & Gamble Company | Screening methods of modulating adrenergic receptor gene expressions implicated in melanogenesis |
| CN110769855A (zh) * | 2017-04-21 | 2020-02-07 | 史蒂文·霍夫曼 | 用于治疗视网膜病变的组合物和方法 |
| WO2019213358A1 (en) * | 2018-05-03 | 2019-11-07 | Alimera Sciences, Inc. | Methods of treating retinal diseases |
| JP7392219B2 (ja) * | 2020-01-20 | 2023-12-06 | 株式会社萌芽プランツ | フラボノイド組成物 |
| US20230248671A1 (en) * | 2020-07-10 | 2023-08-10 | Chang Gung Memorial Hospital, Linkou | Use of beta-1 adrenergic receptor antagonist for preparing compositions for reducing epithelial cell damage induced by epidermal growth factor receptor inhibitors and inhibiting cancer cells |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2330383A1 (fr) | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
| US4443432A (en) | 1981-10-05 | 1984-04-17 | Alcon Laboratories, Inc. | Ophthmalic irrigating solution |
| US5554367A (en) * | 1984-10-31 | 1996-09-10 | Alcon Laboratories, Inc. | Compositions for treatment of glaucoma |
| AU4582797A (en) | 1996-09-13 | 1998-04-02 | Regents Of The University Of California, The | Methods for treatment of retinal diseases |
| US6486208B1 (en) * | 1998-09-25 | 2002-11-26 | Alcon Laboratories, Inc. | Sustained release, and comfortable opthalmic composition and method for ocular therapy |
| CN1245966C (zh) | 1999-11-30 | 2006-03-22 | 爱尔康公司 | β-肾上腺素受体拮抗剂用于制备治疗外层视网膜疾病的药物的用途 |
-
2000
- 2000-11-29 CN CNB008163510A patent/CN1245966C/zh not_active Expired - Fee Related
- 2000-11-29 WO PCT/US2000/032575 patent/WO2001043737A1/en not_active Ceased
- 2000-11-29 EP EP00983818A patent/EP1244438B1/en not_active Expired - Lifetime
- 2000-11-29 DK DK00983818T patent/DK1244438T3/da active
- 2000-11-29 JP JP2001544676A patent/JP4758581B2/ja not_active Expired - Fee Related
- 2000-11-29 HK HK02108325.7A patent/HK1047695B/en not_active IP Right Cessation
- 2000-11-29 MX MXPA02005378A patent/MXPA02005378A/es active IP Right Grant
- 2000-11-29 TR TR2003/02008T patent/TR200302008T4/xx unknown
- 2000-11-29 PT PT00983818T patent/PT1244438E/pt unknown
- 2000-11-29 US US10/130,408 patent/US7081482B2/en not_active Expired - Fee Related
- 2000-11-29 AU AU20527/01A patent/AU782524B2/en not_active Ceased
- 2000-11-29 CA CA002388728A patent/CA2388728C/en not_active Expired - Fee Related
- 2000-11-29 DE DE60006584T patent/DE60006584T2/de not_active Expired - Lifetime
- 2000-11-29 PL PL356001A patent/PL214875B1/pl unknown
- 2000-11-29 AT AT00983818T patent/ATE253905T1/de active
- 2000-11-29 ES ES00983818T patent/ES2210023T3/es not_active Expired - Lifetime
- 2000-11-29 BR BR0015938-7A patent/BR0015938A/pt not_active Application Discontinuation
-
2002
- 2002-04-19 ZA ZA200203133A patent/ZA200203133B/en unknown
-
2006
- 2006-05-02 US US11/415,824 patent/US20060199868A1/en not_active Abandoned
-
2008
- 2008-01-04 US US11/969,346 patent/US20080103211A1/en not_active Abandoned
-
2010
- 2010-06-09 US US12/796,942 patent/US8710102B2/en not_active Expired - Fee Related
- 2010-07-06 JP JP2010154379A patent/JP2010215667A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PT1244438E (pt) | 2004-02-27 |
| US7081482B2 (en) | 2006-07-25 |
| MXPA02005378A (es) | 2005-02-25 |
| ES2210023T3 (es) | 2004-07-01 |
| EP1244438B1 (en) | 2003-11-12 |
| CN1245966C (zh) | 2006-03-22 |
| CN1402634A (zh) | 2003-03-12 |
| US8710102B2 (en) | 2014-04-29 |
| CA2388728C (en) | 2009-05-19 |
| PL214875B1 (pl) | 2013-09-30 |
| TR200302008T4 (tr) | 2004-01-21 |
| AU2052701A (en) | 2001-06-25 |
| ATE253905T1 (de) | 2003-11-15 |
| EP1244438A1 (en) | 2002-10-02 |
| HK1047695B (en) | 2004-08-20 |
| US20080103211A1 (en) | 2008-05-01 |
| US20060199868A1 (en) | 2006-09-07 |
| JP4758581B2 (ja) | 2011-08-31 |
| US20020193373A1 (en) | 2002-12-19 |
| US20100249134A1 (en) | 2010-09-30 |
| ZA200203133B (en) | 2003-04-22 |
| DE60006584D1 (de) | 2003-12-18 |
| JP2010215667A (ja) | 2010-09-30 |
| WO2001043737A1 (en) | 2001-06-21 |
| CA2388728A1 (en) | 2001-06-21 |
| DK1244438T3 (da) | 2004-02-23 |
| HK1047695A1 (en) | 2003-03-07 |
| PL356001A1 (en) | 2004-05-31 |
| JP2003516963A (ja) | 2003-05-20 |
| AU782524B2 (en) | 2005-08-04 |
| DE60006584T2 (de) | 2004-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 10 ( VII ) DA LPI. |
|
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |