BR0017148A - Molécula de ácido nucleico isolada, vetor, célula hospedeira, método para produzir um polipeptìdeo, polipeptìdeo de caminho metabólico, polipeptìdeo isolado, e, métodos para produzir um produto quìmico fino e para modular o rendimento de um produto quìmico fino a partir de uma célula - Google Patents
Molécula de ácido nucleico isolada, vetor, célula hospedeira, método para produzir um polipeptìdeo, polipeptìdeo de caminho metabólico, polipeptìdeo isolado, e, métodos para produzir um produto quìmico fino e para modular o rendimento de um produto quìmico fino a partir de uma célulaInfo
- Publication number
- BR0017148A BR0017148A BR0017148-4A BR0017148A BR0017148A BR 0017148 A BR0017148 A BR 0017148A BR 0017148 A BR0017148 A BR 0017148A BR 0017148 A BR0017148 A BR 0017148A
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- producing
- fine chemical
- nucleic acid
- isolated
- Prior art date
Links
- 102000039446 nucleic acids Human genes 0.000 title abstract 5
- 108020004707 nucleic acids Proteins 0.000 title abstract 5
- 150000007523 nucleic acids Chemical class 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title 3
- 239000012847 fine chemical Substances 0.000 title 2
- 230000037353 metabolic pathway Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 241000186226 Corynebacterium glutamicum Species 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 2
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18797000P | 2000-03-09 | 2000-03-09 | |
| US60674000A | 2000-06-23 | 2000-06-23 | |
| PCT/IB2000/002035 WO2001066573A2 (en) | 2000-03-09 | 2000-12-22 | Corynebacterium glutamicum genes encoding metabolic pathway proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR0017148A true BR0017148A (pt) | 2003-03-11 |
| BRPI0017148B1 BRPI0017148B1 (pt) | 2016-03-01 |
Family
ID=26883605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0017148A BRPI0017148B1 (pt) | 2000-03-09 | 2000-12-22 | vetor, célula hospedeira recombinante, e, método para produzir um produto químico fino |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1261718B1 (pt) |
| JP (1) | JP4786107B2 (pt) |
| KR (1) | KR101012231B1 (pt) |
| CN (2) | CN101255431B (pt) |
| AT (1) | ATE486941T1 (pt) |
| AU (2) | AU2001223903B2 (pt) |
| BR (1) | BRPI0017148B1 (pt) |
| CA (1) | CA2402186C (pt) |
| DE (1) | DE60045191D1 (pt) |
| DK (1) | DK1261718T3 (pt) |
| ES (1) | ES2354867T3 (pt) |
| MX (1) | MXPA02008710A (pt) |
| WO (1) | WO2001066573A2 (pt) |
| ZA (1) | ZA200208060B (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10109685A1 (de) * | 2000-09-09 | 2002-04-11 | Degussa | Neue für das sahH-Gen kodierende Nukleotidsequenzen |
| AU2001279755A1 (en) * | 2000-09-09 | 2002-03-22 | Degussa A.G. | Nucleotide sequences which code for the sahh gene |
| US6759224B2 (en) | 2000-09-09 | 2004-07-06 | Degussa Ag | Nucleotide sequences which code for the sahH gene |
| DE10154292A1 (de) * | 2001-11-05 | 2003-05-15 | Basf Ag | Gene die für Stoffwechselweg-Proteine codieren |
| DE10162729A1 (de) | 2001-12-20 | 2003-07-03 | Degussa | Allele des sigA-Gens aus coryneformen Bakterien |
| DE10222858A1 (de) * | 2002-05-23 | 2003-12-04 | Basf Ag | Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien |
| US8030045B2 (en) * | 2006-08-30 | 2011-10-04 | Cargill, Incorporated | Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production |
| KR100830289B1 (ko) * | 2007-01-18 | 2008-05-16 | 씨제이제일제당 (주) | L-아르기닌 생산 변이주 및 이의 제조방법 |
| KR100987281B1 (ko) | 2008-01-31 | 2010-10-12 | 씨제이제일제당 (주) | 개량된 프로모터 및 이를 이용한 l-라이신의 생산 방법 |
| US8404465B2 (en) | 2009-03-11 | 2013-03-26 | Celexion, Llc | Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks |
| AU2012327243A1 (en) | 2012-08-17 | 2014-03-06 | Celexion, Llc | Biological synthesis of difunctional hexanes and pentanes from carbohydrate feedstocks |
| CN104561194A (zh) * | 2013-10-16 | 2015-04-29 | 南京工业大学 | 一种n-乙酰神经氨酸醛缩酶在催化合成n-乙酰神经氨酸中的应用 |
| CN103805552B (zh) * | 2014-02-19 | 2016-03-23 | 中国科学院天津工业生物技术研究所 | 一株生物合成稀少糖的谷氨酸棒杆菌工程菌株及其构建方法和应用 |
| CN104535511A (zh) * | 2014-07-04 | 2015-04-22 | 陶淑芳 | 基于单酶反应的l-谷氨酰胺的比色测定方法以及测定试剂盒 |
| WO2018079684A1 (en) | 2016-10-26 | 2018-05-03 | Ajinomoto Co., Inc. | Method for producing objective substance |
| JP2019531759A (ja) * | 2016-10-26 | 2019-11-07 | 味の素株式会社 | 目的物質の製造方法 |
| EP3456833A1 (en) * | 2017-09-18 | 2019-03-20 | Evonik Degussa GmbH | Method for the fermentative production of l-amino acids |
| CN112251457B (zh) * | 2019-07-22 | 2022-04-15 | 江南大学 | 一种4-羟基异亮氨酸生产菌的适应性进化方法及其应用 |
| CN111607601B (zh) * | 2020-04-24 | 2022-10-18 | 天津大学 | 谷氨酸棒杆菌转录调控因子IpsA突变体及应用 |
| CN112812985B (zh) * | 2020-11-11 | 2023-01-10 | 新疆阜丰生物科技有限公司 | 一种提高谷氨酰胺发酵产酸的方法 |
| KR102281366B1 (ko) * | 2021-01-26 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 테트라하이드로디피콜리네이트 n-숙시닐트랜스퍼라제 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102303747B1 (ko) * | 2021-04-12 | 2021-09-16 | 씨제이제일제당 (주) | 신규한 주요 촉진제 수퍼패밀리 퍼미에이즈 변이체 및 이를 이용한 l-라이신 생산 방법 |
| CN114410614B (zh) * | 2021-12-30 | 2024-08-20 | 宁夏伊品生物科技股份有限公司 | Yh66_05415蛋白或其突变体在制备l-精氨酸中的应用 |
| CN119242549B (zh) * | 2024-11-19 | 2025-06-27 | 江南大学 | 重组谷氨酸棒杆菌及其发酵生产谷胱甘肽的方法与应用 |
| CN119823930B (zh) * | 2025-03-18 | 2025-05-16 | 山东大学 | 一种脱氮硫杆菌突变株及其构建方法、一种菌剂及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5540240B1 (pt) * | 1970-02-06 | 1980-10-16 | ||
| JP4075087B2 (ja) * | 1996-12-05 | 2008-04-16 | 味の素株式会社 | L−リジンの製造法 |
| MXPA01013123A (es) * | 1999-06-25 | 2002-06-21 | Basf Ag | Genes de corynebacterium glutamicum que codifican proteinas de via metabolica. |
| JP4623825B2 (ja) * | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
-
2000
- 2000-12-22 CA CA2402186A patent/CA2402186C/en not_active Expired - Fee Related
- 2000-12-22 MX MXPA02008710A patent/MXPA02008710A/es active IP Right Grant
- 2000-12-22 JP JP2001565737A patent/JP4786107B2/ja not_active Expired - Fee Related
- 2000-12-22 DK DK00987602.0T patent/DK1261718T3/da active
- 2000-12-22 KR KR1020027011741A patent/KR101012231B1/ko not_active Expired - Fee Related
- 2000-12-22 CN CN2008100909127A patent/CN101255431B/zh not_active Expired - Fee Related
- 2000-12-22 WO PCT/IB2000/002035 patent/WO2001066573A2/en not_active Ceased
- 2000-12-22 AU AU2001223903A patent/AU2001223903B2/en not_active Ceased
- 2000-12-22 BR BRPI0017148A patent/BRPI0017148B1/pt not_active IP Right Cessation
- 2000-12-22 ES ES00987602T patent/ES2354867T3/es not_active Expired - Lifetime
- 2000-12-22 AT AT00987602T patent/ATE486941T1/de not_active IP Right Cessation
- 2000-12-22 DE DE60045191T patent/DE60045191D1/de not_active Expired - Lifetime
- 2000-12-22 AU AU2390301A patent/AU2390301A/xx active Pending
- 2000-12-22 EP EP00987602A patent/EP1261718B1/en not_active Expired - Lifetime
- 2000-12-22 CN CN00819506A patent/CN1452659A/zh active Pending
-
2002
- 2002-10-08 ZA ZA200208060A patent/ZA200208060B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020086616A (ko) | 2002-11-18 |
| DK1261718T3 (da) | 2011-02-14 |
| JP4786107B2 (ja) | 2011-10-05 |
| WO2001066573A2 (en) | 2001-09-13 |
| CN101255431A (zh) | 2008-09-03 |
| EP1261718A2 (en) | 2002-12-04 |
| CA2402186C (en) | 2011-04-05 |
| DE60045191D1 (de) | 2010-12-16 |
| ATE486941T1 (de) | 2010-11-15 |
| AU2390301A (en) | 2001-09-17 |
| JP2003525623A (ja) | 2003-09-02 |
| AU2001223903B2 (en) | 2006-11-02 |
| ES2354867T3 (es) | 2011-03-18 |
| WO2001066573A3 (en) | 2002-05-10 |
| EP1261718B1 (en) | 2010-11-03 |
| ZA200208060B (en) | 2003-11-10 |
| CN101255431B (zh) | 2012-05-16 |
| CN1452659A (zh) | 2003-10-29 |
| KR101012231B1 (ko) | 2011-02-09 |
| CA2402186A1 (en) | 2001-09-13 |
| BRPI0017148B1 (pt) | 2016-03-01 |
| MXPA02008710A (es) | 2003-02-24 |
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| B25A | Requested transfer of rights approved |
Owner name: EVONIK DEGUSSA GMBH (DE) Free format text: TRANSFERIDO DE: BASF SE |
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Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 01/03/2016, OBSERVADAS AS CONDICOES LEGAIS. |
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| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
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