BR0107480A - Processo para a preparação de um composto - Google Patents

Processo para a preparação de um composto

Info

Publication number
BR0107480A
BR0107480A BR0107480-6A BR0107480A BR0107480A BR 0107480 A BR0107480 A BR 0107480A BR 0107480 A BR0107480 A BR 0107480A BR 0107480 A BR0107480 A BR 0107480A
Authority
BR
Brazil
Prior art keywords
preparation
compound
tert
acid
butylhydroxylamine
Prior art date
Application number
BR0107480-6A
Other languages
English (en)
Inventor
J Rgen Blixt
Henry Kruk
Ulf Larsson
John Mcginley
Sergei Pouhov
John Vajda
Allan Wilcox
Original Assignee
Astrazeneca Ab
Centaur Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Centaur Pharmaceuticals Inc filed Critical Astrazeneca Ab
Publication of BR0107480A publication Critical patent/BR0107480A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/46—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/22—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof from sulfonic acids, by reactions not involving the formation of sulfo or halosulfonyl groups; from sulfonic halides by reactions not involving the formation of halosulfonyl groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/10—Process efficiency

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE UM COMPOSTO". Um processo integrado para a preparação de <244>-(2,4-dissulfofenila)-N-terc-butilnitrona e seus sais é apresentado em que o sal de adição de ácido de N-terc-butilidroxilamina é incompletamente neutralizado de modo a deixar quantidades catalíticas de ácido e o produto da neutralização é condensado com um aldeído apropriado.
BR0107480-6A 2000-01-10 2001-01-04 Processo para a preparação de um composto BR0107480A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0000056A SE0000056D0 (sv) 2000-01-10 2000-01-10 Novel process
PCT/SE2001/000008 WO2001051461A1 (en) 2000-01-10 2001-01-04 NOVEL PROCESS FOR THE PREPARATION OF α-(2-4-DISULFOPHENYL)-N-TERT-BUTYLNITRONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

Publications (1)

Publication Number Publication Date
BR0107480A true BR0107480A (pt) 2002-09-03

Family

ID=20278056

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0107480-6A BR0107480A (pt) 2000-01-10 2001-01-04 Processo para a preparação de um composto

Country Status (21)

Country Link
US (1) US6689911B2 (pt)
EP (1) EP1250320B1 (pt)
JP (1) JP2003519679A (pt)
KR (1) KR100721882B1 (pt)
CN (1) CN1263735C (pt)
AR (1) AR029430A1 (pt)
AT (1) ATE272616T1 (pt)
AU (1) AU783256B2 (pt)
BR (1) BR0107480A (pt)
CA (1) CA2396008A1 (pt)
DE (1) DE60104649T2 (pt)
ES (1) ES2225467T3 (pt)
IL (1) IL150402A0 (pt)
MX (1) MXPA02006673A (pt)
MY (1) MY120868A (pt)
NO (1) NO20023318L (pt)
PT (1) PT1250320E (pt)
SE (1) SE0000056D0 (pt)
SI (1) SI1250320T1 (pt)
WO (1) WO2001051461A1 (pt)
ZA (1) ZA200204875B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds
AU2009214727B2 (en) 2008-02-12 2014-12-11 Tosk, Incorporated Doxorubicin adjuvants to reduce toxicity and methods for using the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3397234A (en) 1964-06-17 1968-08-13 Du Pont Process for the preparation of alpha-phenyl-nu-methyl nitrone
FR1437188A (fr) 1964-06-17 1966-04-29 Du Pont Procédé de fabrication d'alpha-phényl-nu-méthyl nitrone
US5488145A (en) * 1993-12-23 1996-01-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps

Also Published As

Publication number Publication date
US20030069442A1 (en) 2003-04-10
ATE272616T1 (de) 2004-08-15
CN1263735C (zh) 2006-07-12
MXPA02006673A (es) 2004-09-10
NO20023318L (no) 2002-08-15
CA2396008A1 (en) 2001-07-19
CN1394200A (zh) 2003-01-29
EP1250320A1 (en) 2002-10-23
AR029430A1 (es) 2003-06-25
NO20023318D0 (no) 2002-07-09
JP2003519679A (ja) 2003-06-24
DE60104649T2 (de) 2005-08-11
AU2720401A (en) 2001-07-24
KR20020091078A (ko) 2002-12-05
AU783256B2 (en) 2005-10-06
SE0000056D0 (sv) 2000-01-10
EP1250320B1 (en) 2004-08-04
PT1250320E (pt) 2004-11-30
SI1250320T1 (en) 2005-02-28
WO2001051461A1 (en) 2001-07-19
US6689911B2 (en) 2004-02-10
KR100721882B1 (ko) 2007-05-25
ES2225467T3 (es) 2005-03-16
MY120868A (en) 2005-11-30
IL150402A0 (en) 2002-12-01
ZA200204875B (en) 2003-09-18
DE60104649D1 (de) 2004-09-09

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 8A. ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2012 DE 28/07/2009.