BR0108002A - Derivados de amidas heterocìclicas - Google Patents

Derivados de amidas heterocìclicas

Info

Publication number
BR0108002A
BR0108002A BR0108002-4A BR0108002A BR0108002A BR 0108002 A BR0108002 A BR 0108002A BR 0108002 A BR0108002 A BR 0108002A BR 0108002 A BR0108002 A BR 0108002A
Authority
BR
Brazil
Prior art keywords
derivatives
heterocyclic amides
heterocyclic
amides
useful
Prior art date
Application number
BR0108002-4A
Other languages
English (en)
Inventor
Matthew Frank Brown
Christopher Stanley Poss
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0108002A publication Critical patent/BR0108002A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

"DERIVADOS DE AMIDAS HETEROCìCLICAS". Um composto da fórmula ou o seu sal farmaceuticamente aceitável; em que R^ 1^, R^ 2^, R^ 3^ e R^ 4^ são como definidos acima, proveitosos para tratar a inflamação e outras doenças imunes.
BR0108002-4A 2000-02-04 2001-01-26 Derivados de amidas heterocìclicas BR0108002A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18015900P 2000-02-04 2000-02-04
PCT/IB2001/000107 WO2001057023A1 (en) 2000-02-04 2001-01-26 Heterocyclic amide derivatives

Publications (1)

Publication Number Publication Date
BR0108002A true BR0108002A (pt) 2002-10-29

Family

ID=22659425

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0108002-4A BR0108002A (pt) 2000-02-04 2001-01-26 Derivados de amidas heterocìclicas

Country Status (38)

Country Link
US (2) US6548671B2 (pt)
EP (1) EP1252154A1 (pt)
JP (1) JP2003522164A (pt)
KR (2) KR20050009776A (pt)
CN (1) CN1398265A (pt)
AP (1) AP2002002595A0 (pt)
AR (1) AR027349A1 (pt)
AU (1) AU2699701A (pt)
BG (1) BG106922A (pt)
BR (1) BR0108002A (pt)
CA (1) CA2399214A1 (pt)
CZ (1) CZ20022542A3 (pt)
EA (2) EA200401099A1 (pt)
EE (1) EE200200432A (pt)
GE (1) GEP20043301B (pt)
GT (1) GT200100021A (pt)
HK (1) HK1050006A1 (pt)
HN (1) HN2001000021A (pt)
HR (1) HRP20020638A2 (pt)
HU (1) HUP0204560A3 (pt)
IL (1) IL150862A0 (pt)
IS (1) IS6468A (pt)
MA (1) MA25653A1 (pt)
NO (1) NO20023675L (pt)
NZ (1) NZ520075A (pt)
OA (1) OA12174A (pt)
PA (1) PA8511401A1 (pt)
PE (1) PE20011057A1 (pt)
PL (1) PL357094A1 (pt)
PY (1) PY0102270A (pt)
SK (1) SK10882002A3 (pt)
SV (1) SV2002000302A (pt)
TN (1) TNSN01021A1 (pt)
TW (1) TW200804311A (pt)
UA (1) UA72789C2 (pt)
UY (1) UY26568A1 (pt)
WO (1) WO2001057023A1 (pt)
ZA (1) ZA200206140B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003043997A1 (en) * 2001-11-15 2003-05-30 Eli Lilly And Company Peroxisome proliferator activated receptor alpha agonists
SE0201980D0 (sv) * 2002-06-24 2002-06-24 Astrazeneca Ab Novel compounds
US20040087571A1 (en) * 2002-10-30 2004-05-06 Pfizer Inc Methods of using CCR1 antagonists as immunomodulatory agents
US20040097554A1 (en) * 2002-10-30 2004-05-20 Pfizer Inc Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents
CA2628179A1 (en) * 2005-11-15 2007-05-24 Vertex Pharmaceuticals Incorporated Azaindazoles useful as inhibitors of kinases
CN1971279B (zh) * 2006-12-06 2011-05-18 华中农业大学 喹噁啉-2-羧酸残留的酶联免疫检测方法及试剂盒
LT3609868T (lt) 2017-03-13 2023-12-11 Raqualia Pharma Inc. Tetrahidrochinolino dariniai kaip p2x7 receptoriaus antagonistai

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL88619A0 (en) * 1987-12-15 1989-07-31 Pfizer Non-peptidic renin inhibitors
EP0374098A3 (de) * 1988-12-15 1991-05-02 Ciba-Geigy Ag Retrovirale Proteasehemmer
WO1993005026A1 (en) 1991-09-11 1993-03-18 Smithkline Beecham Corporation Peptide isoters containing a heterocycle as h.i.v. inhibitors
AU3735793A (en) * 1992-02-26 1993-09-13 Smithkline Beecham Corporation Retroviral protease inhibitors
PT708085E (pt) * 1994-10-19 2002-11-29 Novartis Ag Eteres antivirais de isosteros de substrato de aspartato protease
CN1248968A (zh) * 1997-02-26 2000-03-29 辉瑞大药厂 杂芳基－己酸酰胺衍生物、其制备方法及其作为MIP－1α与其CCRI受体结合的选择性抑制剂的用途
TR200002248T2 (tr) * 1998-02-05 2000-12-21 Pfizer Products Inc. Yeni dihidroksiheksanoik asit türevleri

Also Published As

Publication number Publication date
AR027349A1 (es) 2003-03-26
IS6468A (is) 2002-07-11
AP2002002595A0 (en) 2002-09-30
NZ520075A (en) 2004-02-27
BG106922A (bg) 2003-03-31
CZ20022542A3 (cs) 2003-08-13
EP1252154A1 (en) 2002-10-30
PA8511401A1 (es) 2002-09-17
KR20020072304A (ko) 2002-09-14
JP2003522164A (ja) 2003-07-22
UA72789C2 (en) 2005-04-15
US6689886B2 (en) 2004-02-10
US20020132810A1 (en) 2002-09-19
NO20023675L (no) 2002-09-10
EA200401099A1 (ru) 2005-02-24
OA12174A (en) 2006-05-09
TNSN01021A1 (fr) 2005-11-10
HUP0204560A2 (en) 2003-05-28
HN2001000021A (es) 2001-07-08
PY0102270A (es) 2003-10-01
TW200804311A (en) 2008-01-16
KR20050009776A (ko) 2005-01-25
US6548671B2 (en) 2003-04-15
AU2699701A (en) 2001-08-14
SK10882002A3 (sk) 2003-10-07
EA005320B1 (ru) 2005-02-24
SV2002000302A (es) 2002-07-16
CA2399214A1 (en) 2001-08-09
PL357094A1 (pl) 2004-07-12
GT200100021A (es) 2001-01-31
GEP20043301B (en) 2004-02-10
NO20023675D0 (no) 2002-08-02
PE20011057A1 (es) 2001-10-22
HK1050006A1 (zh) 2003-06-06
UY26568A1 (es) 2001-08-27
HUP0204560A3 (en) 2005-03-29
HRP20020638A2 (en) 2004-12-31
ZA200206140B (en) 2003-08-01
WO2001057023A1 (en) 2001-08-09
US20030204086A1 (en) 2003-10-30
EE200200432A (et) 2003-12-15
IL150862A0 (en) 2003-02-12
EA200200749A1 (ru) 2002-12-26
MA25653A1 (fr) 2002-12-31
CN1398265A (zh) 2003-02-19

Similar Documents

Publication Publication Date Title
BR0109703A (pt) Derivados de piperazina
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
BR0215240A (pt) Derivados de calcona e seu uso no tratamento de doenças
TR200000059T2 (tr) Piridin türevleri
DE69528005D1 (de) Prolineamid-Derivate
DE69925133D1 (de) Pyrrolobenzodiazepine
TR200201505T2 (tr) Terapötik maddeler olarak pirazolopirimidinler
UY26082A1 (es) Derivados de 1,4-diazabiciclo [3.2.2] nonan-4-carboxilato y -carboxamidas, su preparacion y su aplicacion en terapeutica
BR0208338A (pt) Derivados de piridina
DE69823843D1 (de) Benzimidazolinone, benzoxazolinone, benzopiperazinone, indanone und deren derivate als faktor xa inhibitoren
ATE233274T1 (de) Oxyiminopregnancarbolactone
BR0108816A (pt) Derivados de quinolina como antagonistas alfa-2
BR0210531A (pt) Derivados de ácido sulfÈnico
PE20030061A1 (es) 1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4
BR0315662A (pt) Derivados de 1-(4-benzil-piperazin-1-il)-3-fenil-propenona
BR0313727A (pt) Derivados de isoquinolina como inibidores de metaloproteinase da matriz
BR0114697A (pt) Derivados em ponte de piperazina
DE69931378D1 (de) Chinazolin derivate und therapeutische verwendungen davon
ATE330958T1 (de) Pyrazino 1'2':1,6öpyrido 3,4-böindolderivate
NZ504614A (en) Echinocandin derivatives and application as anti-fungal agents
AP2002002595A0 (en) Heterocyclic amide derivatives.
NO20020914D0 (no) Alkoksy-substituerte benzimidazolforbindelser, preparater inneholdende slike samt anvendelser derav
EA200400877A1 (ru) 2'-гало-3',5'-диалкоксифен-1'-илимино-2-имидазолидиновые производные и их применение для лечения недержания мочи
ATE140922T1 (de) 3- oder 4-glykosyloxybenzopyranderivat und dieses enthaltende antiallergisches mittel
BR0201288A (pt) Derivados de piperazina

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6O, 7O E 8O ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2016 DE 25/08/2009