BR0111018A - Formulações estáveis lìquidas e sólidas - Google Patents
Formulações estáveis lìquidas e sólidasInfo
- Publication number
- BR0111018A BR0111018A BR0111018-7A BR0111018A BR0111018A BR 0111018 A BR0111018 A BR 0111018A BR 0111018 A BR0111018 A BR 0111018A BR 0111018 A BR0111018 A BR 0111018A
- Authority
- BR
- Brazil
- Prior art keywords
- stable
- liquid
- stable formulations
- solid stable
- loratadine
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000007787 solid Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 239000007788 liquid Substances 0.000 title 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 2
- 239000000739 antihistaminic agent Substances 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 2
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 abstract 2
- 229960003088 loratadine Drugs 0.000 abstract 2
- 239000000133 nasal decongestant Substances 0.000 abstract 2
- 239000000932 sedative agent Substances 0.000 abstract 2
- 230000001624 sedative effect Effects 0.000 abstract 2
- CAVQBDOACNULDN-NRCOEFLKSA-N (1s,2s)-2-(methylamino)-1-phenylpropan-1-ol;sulfuric acid Chemical compound OS(O)(=O)=O.CN[C@@H](C)[C@@H](O)C1=CC=CC=C1.CN[C@@H](C)[C@@H](O)C1=CC=CC=C1 CAVQBDOACNULDN-NRCOEFLKSA-N 0.000 abstract 1
- JBDGDEWWOUBZPM-XYPYZODXSA-N ambroxol Chemical compound NC1=C(Br)C=C(Br)C=C1CN[C@@H]1CC[C@@H](O)CC1 JBDGDEWWOUBZPM-XYPYZODXSA-N 0.000 abstract 1
- 229960005174 ambroxol Drugs 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000011109 contamination Methods 0.000 abstract 1
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 239000003172 expectorant agent Substances 0.000 abstract 1
- 230000003419 expectorant effect Effects 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960003908 pseudoephedrine Drugs 0.000 abstract 1
- KWGRBVOPPLSCSI-WCBMZHEXSA-N pseudoephedrine Chemical compound CN[C@@H](C)[C@@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WCBMZHEXSA-N 0.000 abstract 1
- 229960004159 pseudoephedrine sulfate Drugs 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
"FORMULAçõES ESTáVEIS LìQUIDAS E SóLIDAS". Composições farmacêuticas estáveis contendo anti-histamínicos não-sedativos tais como loratadina e um descongestionante nasal tal como sulfato de pseudoefedrina e no mínimo um veículo farmaceuticamente aceitável, e composições farmaceuticamente estáveis contendo anti-histamínicos não-sedativos tais como loratadina, descongestionantes nasais tais como pseudoefedrina, e um expectorante tal como Ambroxol e mínimo um veículo farmaceuticamente aceitável os quais são estáveis a degradação química e física e contaminação microbiana.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MXPA/A/2000/005129A MXPA00005129A (en) | 2000-05-24 | Liquid and stable antihistaminic - anti-congestive pharmaceutical compositions | |
| PCT/US2001/016570 WO2001089527A2 (en) | 2000-05-24 | 2001-05-22 | Pharmaceutical composition comprising loratadine and a nasal decongestant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0111018A true BR0111018A (pt) | 2004-02-17 |
Family
ID=33308448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0111018-7A BR0111018A (pt) | 2000-05-25 | 2001-05-22 | Formulações estáveis lìquidas e sólidas |
Country Status (7)
| Country | Link |
|---|---|
| AU (1) | AU2001264806A1 (pt) |
| BR (1) | BR0111018A (pt) |
| CR (1) | CR6804A (pt) |
| EC (1) | ECSP024356A (pt) |
| PA (1) | PA8517201A1 (pt) |
| PE (1) | PE20020055A1 (pt) |
| WO (1) | WO2001089527A2 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6635654B1 (en) | 2003-01-09 | 2003-10-21 | Allergan, Inc. | Ophthalmic compositions containing loratadine |
| AU2005333081B2 (en) | 2005-06-17 | 2010-06-24 | Aft Pharmaceuticals Limited | Novel pharmaceutical composition and its use in a method for treatment of patients with upper respiratory mucosal congestion |
| SG173333A1 (en) * | 2006-06-29 | 2011-08-29 | Schering Corp | Sugar-free storage-stable antihistaminic syrups |
| WO2022159763A1 (en) * | 2021-01-22 | 2022-07-28 | Model Medicines, Inc. | Sars-cov-2 therapeutics |
| CN116898799B (zh) * | 2023-08-30 | 2024-04-30 | 哈尔滨圣泰生物制药有限公司 | 一种地氯雷他定口服制剂及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4783465A (en) * | 1984-04-09 | 1988-11-08 | Analgesic Associates | Cough/cold mixtures comprising non-sedating antihistamine drugs |
| CN1130354A (zh) * | 1993-09-07 | 1996-09-04 | 普罗克特和廿保尔公司 | 含有丙酸类非甾体消炎药氨基酸盐和减充血药、祛痰药、抗组胺药和镇咳药中至少一种的组合物 |
| EP0941091A1 (en) * | 1996-10-31 | 1999-09-15 | Schering Corporation | Composition, for the treatment of asthma, containing loratadine and a decongestant |
| US6132758A (en) * | 1998-06-01 | 2000-10-17 | Schering Corporation | Stabilized antihistamine syrup |
| US6051585A (en) * | 1998-12-07 | 2000-04-18 | Weinstein; Robert E. | Single-dose antihistamine/decongestant formulations for treating rhinitis |
| JP5592042B2 (ja) * | 2000-04-14 | 2014-09-17 | ジェイ−メド ファーマシューティカルズ，インコーポレーティッド | 鼻炎治療のための単一投与抗ヒスタミン薬／鬱血除去薬製剤 |
-
2001
- 2001-05-22 PE PE2001000462A patent/PE20020055A1/es not_active Application Discontinuation
- 2001-05-22 AU AU2001264806A patent/AU2001264806A1/en not_active Withdrawn
- 2001-05-22 BR BR0111018-7A patent/BR0111018A/pt not_active Application Discontinuation
- 2001-05-22 WO PCT/US2001/016570 patent/WO2001089527A2/en not_active Ceased
- 2001-05-22 PA PA20018517201A patent/PA8517201A1/es unknown
-
2002
- 2002-10-31 CR CR6804A patent/CR6804A/es not_active Application Discontinuation
- 2002-11-22 EC EC2002004356A patent/ECSP024356A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001264806A1 (en) | 2001-12-03 |
| WO2001089527A3 (en) | 2003-10-16 |
| CR6804A (es) | 2008-10-29 |
| PA8517201A1 (es) | 2002-08-26 |
| PE20020055A1 (es) | 2002-02-12 |
| WO2001089527A2 (en) | 2001-11-29 |
| ECSP024356A (es) | 2003-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Technical examination (opinion): publication of technical examination (opinion) | ||
| B09B | Decision: refusal |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11, 13 E 25 DA LPI |
|
| B09B | Decision: refusal |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |