BR0111297A - Promotor de migração epitelial corneana - Google Patents

Promotor de migração epitelial corneana

Info

Publication number
BR0111297A
BR0111297A BR0111297-0A BR0111297A BR0111297A BR 0111297 A BR0111297 A BR 0111297A BR 0111297 A BR0111297 A BR 0111297A BR 0111297 A BR0111297 A BR 0111297A
Authority
BR
Brazil
Prior art keywords
corneal epithelial
group
epithelial migration
migration promoter
compounds
Prior art date
Application number
BR0111297-0A
Other languages
English (en)
Inventor
Katsuhiko Nakata
Masatsugu Nakamura
Tsutomu Fujihara
Hiromi Fujita
Original Assignee
Santen Pharmaceutical Co Ltd
Inspire Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18664160&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0111297(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Santen Pharmaceutical Co Ltd, Inspire Pharmaceuticals Inc filed Critical Santen Pharmaceutical Co Ltd
Publication of BR0111297A publication Critical patent/BR0111297A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"PROMOTOR DE MIGRAçãO EPITELIAL CORNEANA". Com base em pesquisa para compostos que podem apresentar um efeito promotor de migração epitelial corneana em oftalmologia, a presente invenção proporciona promotores de migração epitelial corneana de agonista receptor P2Y, tais como compostos de ácido fosfórico, tendo um grupo adenosila, grupo uridila, grupo xantosila, grupo guanosila ou grupo timidila, ou os seus sais, com excelentes efeitos promotores de migração epitelial corneana.
BR0111297-0A 2000-05-30 2001-05-30 Promotor de migração epitelial corneana BR0111297A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000159889 2000-05-30
PCT/JP2001/004520 WO2001091795A1 (en) 2000-05-30 2001-05-30 Ectocornea extension promoters

Publications (1)

Publication Number Publication Date
BR0111297A true BR0111297A (pt) 2004-01-06

Family

ID=18664160

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0111297-0A BR0111297A (pt) 2000-05-30 2001-05-30 Promotor de migração epitelial corneana

Country Status (9)

Country Link
US (2) US6984629B2 (pt)
EP (1) EP1428538B1 (pt)
KR (1) KR100832821B1 (pt)
CN (1) CN100391538C (pt)
AU (2) AU2001260643B9 (pt)
BR (1) BR0111297A (pt)
CA (1) CA2413928C (pt)
MX (1) MXPA02011710A (pt)
WO (1) WO2001091795A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6864243B1 (en) * 2000-05-12 2005-03-08 Inspire Pharmaceuticals, Inc. Method for treating retinal degeneration with purinergic receptor agonists
JP4313033B2 (ja) 2002-12-27 2009-08-12 株式会社日本点眼薬研究所 眼科用治療組成物
MX2013007502A (es) * 2010-12-28 2013-08-01 Santen Pharmaceutical Co Ltd Solucion oftalmica que comprende diquafosol, metodo para producir la misma, y metodo para inhibir la formacion de precipitado insoluble.
EP3431092A1 (en) * 2012-03-26 2019-01-23 Santen Pharmaceutical Co., Ltd. Ophthalmic solution comprising diquafosol
PH12020551313B1 (en) * 2018-02-28 2024-02-28 Santen Pharmaceutical Co Ltd Ophthalmic composition comprising diquafosol and cationic polymer
KR102656181B1 (ko) * 2019-08-27 2024-04-08 산텐 세이야꾸 가부시키가이샤 디쿠아포솔 또는 그 염 및 폴리비닐피롤리돈을 함유하는 수성 안과용 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292498A (en) * 1991-06-19 1994-03-08 The University Of North Carolina At Chapel Hill Method of treating lung disease with uridine triphosphates
US5900407A (en) 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds
US6696425B2 (en) * 1997-02-06 2004-02-24 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with purinergic receptor agonists
DK0981534T3 (da) * 1997-02-06 2006-09-04 Inspire Pharmaceuticals Inc Dinukleotider og deres anvendelser
CA2332540A1 (en) 1998-05-22 1999-12-02 Benjamin R. Yerxa Therapeutic dinucleotide and derivatives
WO2000050024A2 (en) 1999-02-26 2000-08-31 Inspire Pharmaceuticals, Inc. Method of promoting mucosal hydration with certain uridine, adenine and cytidine diphosphates and analogs thereof
US6409175B1 (en) 1999-07-13 2002-06-25 Grant Prideco, Inc. Expandable joint connector

Also Published As

Publication number Publication date
KR20030031489A (ko) 2003-04-21
EP1428538B1 (en) 2013-08-14
AU2001260643B2 (en) 2006-06-08
MXPA02011710A (es) 2004-07-30
CA2413928C (en) 2011-01-25
US20060009415A1 (en) 2006-01-12
AU6064301A (en) 2001-12-11
CA2413928A1 (en) 2001-12-06
US20030186927A1 (en) 2003-10-02
AU2001260643B9 (en) 2006-10-19
EP1428538A4 (en) 2006-04-05
WO2001091795A1 (en) 2001-12-06
US6984629B2 (en) 2006-01-10
EP1428538A1 (en) 2004-06-16
CN1431914A (zh) 2003-07-23
KR100832821B1 (ko) 2008-05-28
CN100391538C (zh) 2008-06-04

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 45/00, A61K 31/7072, A61K 31/7076, A61K 31/7084, A61P 27/02

Ipc: A61K 31/7072 (2011.01), A61K 31/7076 (2011.01), A6

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.