BR0111530A - Processo para detectar modulação de domìnio cinase de vegf - Google Patents

Processo para detectar modulação de domìnio cinase de vegf

Info

Publication number
BR0111530A
BR0111530A BR0111530-8A BR0111530A BR0111530A BR 0111530 A BR0111530 A BR 0111530A BR 0111530 A BR0111530 A BR 0111530A BR 0111530 A BR0111530 A BR 0111530A
Authority
BR
Brazil
Prior art keywords
kinase domain
domain modulation
vegf kinase
detecting vegf
detection
Prior art date
Application number
BR0111530-8A
Other languages
English (en)
Inventor
Dana L Johnson
Stuart L Emanuel
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of BR0111530A publication Critical patent/BR0111530A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"PROCESSO PARA DETECTAR MODULAçãO DE DOMìNIO CINASE DE VEGF". A presente invenção refere-se a análises para a detecção de compostos com atividade farmacológica, particularmente para a detecção de moduladores do domínio cinase do receptor do fator de crescimento endotelial vascular (domínio cinase de VEGF-R2 de rato).
BR0111530-8A 2000-06-07 2001-06-06 Processo para detectar modulação de domìnio cinase de vegf BR0111530A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21013200P 2000-06-07 2000-06-07
PCT/US2001/018312 WO2001094624A1 (en) 2000-06-07 2001-06-06 Method to detect modulators of vegf kinase domain

Publications (1)

Publication Number Publication Date
BR0111530A true BR0111530A (pt) 2003-07-22

Family

ID=22781690

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0111530-8A BR0111530A (pt) 2000-06-07 2001-06-06 Processo para detectar modulação de domìnio cinase de vegf

Country Status (16)

Country Link
US (1) US7070938B2 (pt)
EP (1) EP1294929B1 (pt)
JP (1) JP2004508016A (pt)
CN (1) CN1457366A (pt)
AT (1) ATE307215T1 (pt)
AU (2) AU6821301A (pt)
BR (1) BR0111530A (pt)
CA (1) CA2411072A1 (pt)
DE (1) DE60114196T2 (pt)
DK (1) DK1294929T3 (pt)
ES (1) ES2250420T3 (pt)
IL (1) IL153309A0 (pt)
MX (1) MXPA02012224A (pt)
NZ (1) NZ523386A (pt)
WO (1) WO2001094624A1 (pt)
ZA (1) ZA200300128B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY128449A (en) 2000-05-24 2007-02-28 Sugen Inc Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568649A (en) 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
US5185438A (en) 1991-04-02 1993-02-09 The Trustees Of Princeton University Nucleic acids encoding hencatoporetic stem cell receptor flk-2
US5861301A (en) 1992-02-20 1999-01-19 American Cayanamid Company Recombinant kinase insert domain containing receptor and gene encoding same
US5770176A (en) 1995-12-08 1998-06-23 Chiron Diagnostics Corporation Assays for functional nuclear receptors
WO1997034920A1 (en) * 1996-03-21 1997-09-25 Sugen, Inc. Assays for kdr/flk-1 receptor tyrosine kinase inhibitors
WO1998058053A1 (en) 1997-06-18 1998-12-23 Merck & Co., Inc. Human receptor tyrosine kinase, kdr
JP2002534058A (ja) * 1998-09-08 2002-10-15 アグロン ファ−マシュ−テイカルズ インコ−ポレイテッド 脈管内皮成長因子レセプタ一２タンパクの修飾方法およびその使用方法

Also Published As

Publication number Publication date
EP1294929A4 (en) 2004-12-29
DE60114196T2 (de) 2006-07-20
EP1294929B1 (en) 2005-10-19
DK1294929T3 (da) 2005-12-12
AU2001268213B2 (en) 2005-11-10
ES2250420T3 (es) 2006-04-16
US7070938B2 (en) 2006-07-04
AU6821301A (en) 2001-12-17
IL153309A0 (en) 2003-07-06
CA2411072A1 (en) 2001-12-13
DE60114196D1 (de) 2006-03-02
US20020037537A1 (en) 2002-03-28
NZ523386A (en) 2004-07-30
ATE307215T1 (de) 2005-11-15
WO2001094624A1 (en) 2001-12-13
CN1457366A (zh) 2003-11-19
EP1294929A1 (en) 2003-03-26
JP2004508016A (ja) 2004-03-18
MXPA02012224A (es) 2004-08-19
ZA200300128B (en) 2004-02-13

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Free format text: JOHNSON & JOHNSON (US)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A,7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2016 DE 25/08/2009.