BR0112721A - Uso de fosfato de estramustina no tratamento de metastase óssea - Google Patents
Uso de fosfato de estramustina no tratamento de metastase ósseaInfo
- Publication number
- BR0112721A BR0112721A BR0112721-7A BR0112721A BR0112721A BR 0112721 A BR0112721 A BR 0112721A BR 0112721 A BR0112721 A BR 0112721A BR 0112721 A BR0112721 A BR 0112721A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- estramustine phosphate
- bone metastasis
- bone
- phosphate
- Prior art date
Links
- 206010027476 Metastases Diseases 0.000 title abstract 2
- 210000000988 bone and bone Anatomy 0.000 title abstract 2
- 229960004750 estramustine phosphate Drugs 0.000 title abstract 2
- ADFOJJHRTBFFOF-RBRWEJTLSA-N estramustine phosphate Chemical compound ClCCN(CCCl)C(=O)OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)OP(O)(O)=O)[C@@H]4[C@@H]3CCC2=C1 ADFOJJHRTBFFOF-RBRWEJTLSA-N 0.000 title abstract 2
- 230000009401 metastasis Effects 0.000 title abstract 2
- 208000006386 Bone Resorption Diseases 0.000 abstract 1
- 229940078581 Bone resorption inhibitor Drugs 0.000 abstract 1
- 206010027452 Metastases to bone Diseases 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 230000024279 bone resorption Effects 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Materials For Medical Uses (AREA)
Abstract
"USO DE FOSFATO DE ESTRAMUSTINA NO TRATAMENTO DE METASTASE óSSEA". O fosfato de estramustina é mostrado para agir como um inibidor de reabsorção óssea e pode ser usado assim, para tratar, prevenir ou aliviar os sintomas de metástase óssea que surgem devido a dita reabsorção óssea.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/625,540 US6436913B1 (en) | 2000-07-25 | 2000-07-25 | Use of estramustine phosphate in the treatment of bone metastasis |
| PCT/US2001/023179 WO2002007719A1 (en) | 2000-07-25 | 2001-07-23 | Use of estramustine phosphate in the treatment of bone metastasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0112721A true BR0112721A (pt) | 2003-06-24 |
Family
ID=24506563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0112721-7A BR0112721A (pt) | 2000-07-25 | 2001-07-23 | Uso de fosfato de estramustina no tratamento de metastase óssea |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6436913B1 (pt) |
| EP (1) | EP1328264A4 (pt) |
| JP (1) | JP2004504346A (pt) |
| KR (1) | KR20030019612A (pt) |
| CN (1) | CN1446086A (pt) |
| AR (1) | AR029958A1 (pt) |
| AU (1) | AU2001277115A1 (pt) |
| BR (1) | BR0112721A (pt) |
| CA (1) | CA2412392A1 (pt) |
| MX (1) | MXPA03000313A (pt) |
| PE (1) | PE20020301A1 (pt) |
| WO (1) | WO2002007719A1 (pt) |
| ZA (1) | ZA200210285B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0003201D0 (en) * | 2000-02-11 | 2000-04-05 | Pharmacia & Upjohn Spa | Method to potentiate the therapeutic efficacy of taxane and derivatives thereof |
| IT1318689B1 (it) * | 2000-09-12 | 2003-08-27 | Pharmacia & Upjohn Spa | Uso dell'arginina nella preparazione di un medicamento per lapreparazione e trattamento degli effetti collaterali associati alla |
| US20040014729A1 (en) * | 2001-07-23 | 2004-01-22 | Beryl Asp | Use of estramustine phosphate in the treatment of bone metastasis |
| WO2005000858A2 (en) * | 2003-06-27 | 2005-01-06 | Akira Odani | Bisphosphonate complexes |
| JP2005055881A (ja) * | 2003-07-22 | 2005-03-03 | Fuji Photo Film Co Ltd | 描画方法および描画装置 |
| CN100340296C (zh) * | 2005-02-03 | 2007-10-03 | 山东蓝金生物工程有限公司 | 一种抗癌体内植入剂 |
| WO2011066379A2 (en) * | 2009-11-24 | 2011-06-03 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | METHOD OF REDUCING INTRATUMORAL pHe AND ACID-MEDIATED INVASION |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4634691A (en) * | 1980-10-07 | 1987-01-06 | The Procter & Gamble Company | Method for inhibiting tumor metastasis |
| US5597830A (en) | 1994-12-20 | 1997-01-28 | Warner-Lambert Company | Combination chemotherapy |
| BR9906425A (pt) * | 1998-03-27 | 2000-07-11 | Upjohn Co | Métodos para potencializar fosfato de estramustina intravenoso |
| WO2000074634A2 (en) * | 1999-06-03 | 2000-12-14 | Au Jessie L S | Methods and compositions for modulating cell proliferation and cell death |
-
2000
- 2000-07-25 US US09/625,540 patent/US6436913B1/en not_active Expired - Fee Related
-
2001
- 2001-07-17 PE PE2001000722A patent/PE20020301A1/es not_active Application Discontinuation
- 2001-07-23 KR KR10-2003-7001068A patent/KR20030019612A/ko not_active Withdrawn
- 2001-07-23 CN CN01813244A patent/CN1446086A/zh active Pending
- 2001-07-23 EP EP01954900A patent/EP1328264A4/en not_active Withdrawn
- 2001-07-23 CA CA002412392A patent/CA2412392A1/en not_active Abandoned
- 2001-07-23 BR BR0112721-7A patent/BR0112721A/pt not_active IP Right Cessation
- 2001-07-23 AR ARP010103500A patent/AR029958A1/es not_active Application Discontinuation
- 2001-07-23 AU AU2001277115A patent/AU2001277115A1/en not_active Abandoned
- 2001-07-23 WO PCT/US2001/023179 patent/WO2002007719A1/en not_active Ceased
- 2001-07-23 MX MXPA03000313A patent/MXPA03000313A/es unknown
- 2001-07-23 JP JP2002513455A patent/JP2004504346A/ja not_active Withdrawn
-
2002
- 2002-12-19 ZA ZA200210285A patent/ZA200210285B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2412392A1 (en) | 2002-01-31 |
| KR20030019612A (ko) | 2003-03-06 |
| EP1328264A4 (en) | 2004-01-28 |
| AR029958A1 (es) | 2003-07-23 |
| EP1328264A1 (en) | 2003-07-23 |
| ZA200210285B (en) | 2003-12-19 |
| PE20020301A1 (es) | 2002-04-07 |
| JP2004504346A (ja) | 2004-02-12 |
| WO2002007719A1 (en) | 2002-01-31 |
| AU2001277115A1 (en) | 2002-02-05 |
| US6436913B1 (en) | 2002-08-20 |
| CN1446086A (zh) | 2003-10-01 |
| MXPA03000313A (es) | 2003-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6O, 7O E 8O ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2021 DE 29/09/2009. |