BR0114680A - Método para a purificação de pravastatina ou de um sal farmacologicamente aceitável da mesma - Google Patents

Método para a purificação de pravastatina ou de um sal farmacologicamente aceitável da mesma

Info

Publication number
BR0114680A
BR0114680A BR0114680-7A BR0114680A BR0114680A BR 0114680 A BR0114680 A BR 0114680A BR 0114680 A BR0114680 A BR 0114680A BR 0114680 A BR0114680 A BR 0114680A
Authority
BR
Brazil
Prior art keywords
acceptable salt
pharmacologically acceptable
purifying pravastatin
pravastatin
purifying
Prior art date
Application number
BR0114680-7A
Other languages
English (en)
Inventor
Nobunari Sugio
Shunshi Kojima
Mutsuo Suzuki
Kiyoshi Hamano
Minoru Hagisawa
Yasuyuki Takamatsu
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of BR0114680A publication Critical patent/BR0114680A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/60—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
    • C07C2602/28—Hydrogenated naphthalenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"MéTODO PARA A PURIFICAçãO DE PRAVASTATINA OU DE UM SAL FARMACOLOGICAMENTE ACEITáVEL DA MESMA". Método para purificação de pravastatina ou seu sal farmacologicamente aceitável por cristalização.
BR0114680-7A 2000-10-16 2001-10-15 Método para a purificação de pravastatina ou de um sal farmacologicamente aceitável da mesma BR0114680A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000315255A JP2002121172A (ja) 2000-10-16 2000-10-16 プラバスタチン又はその薬理上許容される塩の精製方法
PCT/JP2001/009044 WO2002032847A1 (en) 2000-10-16 2001-10-15 Method of purifying pravastatin or its pharmacologically acceptable salt

Publications (1)

Publication Number Publication Date
BR0114680A true BR0114680A (pt) 2003-10-07

Family

ID=18794391

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0114680-7A BR0114680A (pt) 2000-10-16 2001-10-15 Método para a purificação de pravastatina ou de um sal farmacologicamente aceitável da mesma

Country Status (17)

Country Link
US (1) US20030204105A1 (pt)
EP (1) EP1327624A4 (pt)
JP (1) JP2002121172A (pt)
KR (1) KR20030043984A (pt)
CN (1) CN1481352A (pt)
AU (1) AU2001294257A1 (pt)
BR (1) BR0114680A (pt)
CA (1) CA2425882A1 (pt)
CZ (1) CZ2003956A3 (pt)
HU (1) HUP0303123A3 (pt)
IL (1) IL155158A0 (pt)
MX (1) MXPA03003346A (pt)
NO (1) NO20031738L (pt)
PL (1) PL360920A1 (pt)
SK (1) SK4522003A3 (pt)
WO (1) WO2002032847A1 (pt)
ZA (1) ZA200302968B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7642286B2 (en) * 2001-06-21 2010-01-05 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions containing pravastatin
US6716615B2 (en) * 2002-02-27 2004-04-06 Yung Shin Pharmaceutical Ind. Co., Ltd. Strains of saccharaothrix, process for producing pravastatin using the strains and isolation process of (HMG)-CoA reductase
JP4813841B2 (ja) * 2005-07-25 2011-11-09 キユーピー株式会社 プラバスタチンナトリウムの製造方法
WO2009068556A1 (en) * 2007-11-29 2009-06-04 Dsm Ip Assets B.V. Purification of pravastatin
CN111393432A (zh) * 2020-04-09 2020-07-10 北京世纪迈劲生物科技有限公司 去甲托品醇盐析制备方法
CN115925549B (zh) * 2022-12-19 2025-06-06 浦拉司科技（上海）有限责任公司 一种1,3-丙酮二羧酸二甲酯的提纯方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5221594B2 (pt) * 1973-09-29 1977-06-11
GB1543563A (en) * 1975-02-07 1979-04-04 Glaxo Lab Ltd Beta-lactam antibiotic in purified form
MX7065E (es) * 1980-06-06 1987-04-10 Sankyo Co Un procedimiento microbiologico para preparar derivados de ml-236b
NZ250609A (en) * 1992-12-28 1995-07-26 Sankyo Co Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments
JPH06256278A (ja) * 1993-03-03 1994-09-13 Nissan Chem Ind Ltd 光学活性α−カルバモイルアルカン酸誘導体およびその製法
CA2126365C (en) * 1993-07-06 1999-08-24 Steven W. Felman Recovery of citric acid from impure process streams by addition of strong acids and salts thereof
SI20305A (sl) * 1999-08-06 2001-02-28 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristali natrijeve soli pravastatina
SI20070A (sl) * 1998-09-18 2000-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Nove soli inhibitorjev HMG-CoA reduktaze
JP3881240B2 (ja) * 1999-11-30 2007-02-14 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ 醗酵ブロスからスタチン化合物を回収するための方法

Also Published As

Publication number Publication date
HUP0303123A2 (hu) 2004-01-28
WO2002032847A1 (en) 2002-04-25
PL360920A1 (en) 2004-09-20
JP2002121172A (ja) 2002-04-23
US20030204105A1 (en) 2003-10-30
CZ2003956A3 (cs) 2003-09-17
MXPA03003346A (es) 2003-06-19
KR20030043984A (ko) 2003-06-02
CA2425882A1 (en) 2003-04-15
HUP0303123A3 (en) 2004-10-28
ZA200302968B (en) 2004-07-15
SK4522003A3 (en) 2003-11-04
EP1327624A1 (en) 2003-07-16
CN1481352A (zh) 2004-03-10
EP1327624A4 (en) 2004-07-14
IL155158A0 (en) 2003-10-31
AU2001294257A1 (en) 2002-04-29
NO20031738D0 (no) 2003-04-15
NO20031738L (no) 2003-06-11

Similar Documents

Publication Publication Date Title
BR9609744A (pt) Derivados de pirrolidina tendo atividade inibitória de fosfolipase a2
BR0109703A (pt) Derivados de piperazina
BRPI0412763A (pt) formas anidras, hidratadas ou solvatadas de um composto, forma cristalina, composição farmacêutica, e, método para o tratamento ou a profilaxia de distúrbios
BR0115411A (pt) Combinações sinergìsticas compreendendo um inibidor de renina para doenças cardiovasculares
ECSP034436A (es) Sales de valsartan
BR0112395A (pt) Derivados de benzotiazol
BR9809745A (pt) Sal cristalino de amina de cefdinir
PT1259489E (pt) Compostos azapoliciclicos condensados con arilo.
AU2002221078A1 (en) Ultrasonic reflux system for one-step purification of carbon nanostructures
NO20014925L (no) Farmasöytiske forbindelser
BR0113590A (pt) 7-oxo-piridopirimidinas
DK0903347T3 (da) Hidtil ukendte cyclodepsipeptid PF1022-derivater
BR9905089A (pt) Derivados macrolìdeos
BR0101230A (pt) Processo para a preparação de11-amino-3-cloro-6,11-diidro-5-5-dioxo-6-metil-dibenzo[c,f][1,2]tiazepina e aplicação para a sìntese detianeptina
BR0215016A (pt) Piridoquinoxalinas antivirìcas
BR9608506A (pt) "2-Amino-benzoxazinonas para o tratamento de infeccões viróticas
BRPI0412159A (pt) emprego
BR0114680A (pt) Método para a purificação de pravastatina ou de um sal farmacologicamente aceitável da mesma
SE0101082D0 (sv) Novel use
ATE266029T1 (de) Substituierte pyrrolobenzimidazolderivate zur entzündungshemmung
DE69512310D1 (de) Glukopyranosid-Benzothiophene
DE69823240D1 (de) Immunmodulierende arzneimittelzusammenstellung
ES2196174T3 (es) `derivados de sesquiterpeno de actividad antiviral.
BR0207307A (pt) Inibidores de glyt-1
EA200000816A1 (ru) Применение 2-амино-6-трифторметоксибензотиазола для профилактики или лечения дисфункции мозжечка

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 1964 DE 26/08/2008 E CONSIDERANDO A AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS.