BR0115937A - Gene e proteìna de canal de ìon fechado por tensão relacionados com esquizofrenia - Google Patents

Gene e proteìna de canal de ìon fechado por tensão relacionados com esquizofrenia

Info

Publication number
BR0115937A
BR0115937A BR0115937-2A BR0115937A BR0115937A BR 0115937 A BR0115937 A BR 0115937A BR 0115937 A BR0115937 A BR 0115937A BR 0115937 A BR0115937 A BR 0115937A
Authority
BR
Brazil
Prior art keywords
schizophrenia
ion channel
gated ion
protein
channel gene
Prior art date
Application number
BR0115937-2A
Other languages
English (en)
Inventor
Daniel Cohen
Ilya Chumakov
Anne-Marie Simon
Hadi Abderrahim
Original Assignee
Genset Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genset Sa filed Critical Genset Sa
Publication of BR0115937A publication Critical patent/BR0115937A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Plant Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"GENE E PROTEìNA DE CANAL DE ìON FECHADO POR TENSãO RELACIONADOS COM ESQUIZOFRENIA". A presente invenção refere-se a DNA, CDNA e seq³ências de polipeptídeo genómicas de Canlon, uma nova proteína de canal de íon fechado por tensão. A presente invenção também refere-se a marcadores bialélicos do gene de Canlon. O gene de Canlon pode ser usado como um alvo biológico para o tratamento e diagnóstico de esquizofrenia, distúrbio bipolar e outras doenças e condições.
BR0115937-2A 2000-12-05 2001-12-04 Gene e proteìna de canal de ìon fechado por tensão relacionados com esquizofrenia BR0115937A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25131700P 2000-12-05 2000-12-05
PCT/IB2001/002798 WO2002046404A2 (en) 2000-12-05 2001-12-04 Schizophrenia-related voltage-gated ion channel gene and protein

Publications (1)

Publication Number Publication Date
BR0115937A true BR0115937A (pt) 2003-09-30

Family

ID=22951418

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0115937-2A BR0115937A (pt) 2000-12-05 2001-12-04 Gene e proteìna de canal de ìon fechado por tensão relacionados com esquizofrenia

Country Status (16)

Country Link
US (2) US20040091497A1 (pt)
EP (1) EP1339840B1 (pt)
JP (1) JP2004525614A (pt)
KR (1) KR20030074643A (pt)
CN (1) CN1777676A (pt)
AT (1) ATE339500T1 (pt)
AU (2) AU3357302A (pt)
BR (1) BR0115937A (pt)
CA (1) CA2430712A1 (pt)
DE (1) DE60123109T2 (pt)
EA (2) EA006367B1 (pt)
ES (1) ES2271092T3 (pt)
IL (1) IL156073A0 (pt)
MX (1) MXPA03005069A (pt)
UA (1) UA79927C2 (pt)
WO (1) WO2002046404A2 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020042100A1 (en) * 2000-07-03 2002-04-11 Chunhua Yan Isolated human ion channel proteins, nucleic acid molecules encoding human ion channel proteins, and uses thereof
WO2002101035A1 (fr) * 2001-05-10 2002-12-19 Mochida Pharmaceutical Co., Ltd. Proteine du canal cation dependant du potentiel
US7634363B2 (en) 2005-12-07 2009-12-15 Affymetrix, Inc. Methods for high throughput genotyping
US20080075789A1 (en) * 2006-02-28 2008-03-27 The Regents Of The University Of California Genes differentially expressed in bipolar disorder and/or schizophrenia
FR2906532B1 (fr) * 2006-09-28 2008-12-12 Biomerieux Sa Nouvel oligonucleotide marque
BR112017007084A8 (pt) * 2014-10-13 2023-02-07 Dow Agrosciences Llc Moléculas de ácido nucleico subunidade copi coatomer alfa que confere resistância a pragas de coleóptero e hemípteros
KR102807004B1 (ko) * 2020-01-03 2025-05-14 삼성전자주식회사 기판 적층 구조를 포함하는 전자 장치
CN114982679B (zh) * 2022-07-22 2023-08-01 中国水产科学研究院长江水产研究所 一种黄鳝家系建立及优良家系选育方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6008001A (en) * 1993-11-05 1999-12-28 Yeda Research And Development Co. Ltd. Diagnosis of the susceptibility of contracting schizophrenia
WO1999004825A1 (en) * 1997-07-22 1999-02-04 Millennium Pharmaceuticals, Inc. Methods and compositions for the diagnosis and treatment of neuropsychiatric disorders
EP1042468B1 (en) * 1997-12-03 2006-10-18 Merck & Co., Inc. Low-voltage activated calcium channel compositions and methods
AU3530299A (en) * 1998-04-30 1999-11-23 Institut National De La Sante Et De La Recherche Medicale (Inserm) A highly conserved polynucleotide sequence linked to a genetic predisposition toschizophrenia, a method of diagnosis, and applications thereof
CA2331154A1 (en) * 1998-06-16 1999-12-23 Human Genome Sciences, Inc. Polypeptides having sequence identity with acid labile subunit of insulin-like growth factor
WO2000022122A2 (en) * 1998-10-13 2000-04-20 Genset Genes, proteins and biallelic markers related to central nervous system disease
JP2002539845A (ja) * 1999-03-30 2002-11-26 ジェンセット 精神分裂病関連遺伝子、タンパク質およびバイアレリックマーカー
EP1280902A2 (en) * 2000-04-29 2003-02-05 Millennium Pharmaceuticals, Inc. 23949 and 32391, human ion channels and uses thereof
EP1313854A2 (en) * 2000-07-07 2003-05-28 Incyte Genomics, Inc. Transporters and ion channels

Also Published As

Publication number Publication date
DE60123109D1 (de) 2006-10-26
EA008252B1 (ru) 2007-04-27
DE60123109T2 (de) 2007-05-16
EP1339840A2 (en) 2003-09-03
CA2430712A1 (en) 2002-06-13
EP1339840B1 (en) 2006-09-13
EA200300642A1 (ru) 2003-12-25
CN1777676A (zh) 2006-05-24
UA79927C2 (en) 2007-08-10
AU3357302A (en) 2002-06-18
MXPA03005069A (es) 2003-09-05
EA006367B1 (ru) 2005-12-29
JP2004525614A (ja) 2004-08-26
KR20030074643A (ko) 2003-09-19
EA200500974A1 (ru) 2006-02-24
ATE339500T1 (de) 2006-10-15
ES2271092T3 (es) 2007-04-16
IL156073A0 (en) 2003-12-23
US20080184381A1 (en) 2008-07-31
WO2002046404A9 (en) 2002-08-15
WO2002046404A3 (en) 2002-12-12
AU2002233573B2 (en) 2007-03-01
US20040091497A1 (en) 2004-05-13
WO2002046404A2 (en) 2002-06-13

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Legal Events

Date Code Title Description
B25F Entry of change of name and/or headquarter and transfer of application, patent and certif. of addition of invention: change of name on requirement

Owner name: GENSET (FR)

Free format text: A FIM DE ATENDER AO PEDIDO DE ALTERACAO DE NOME CONTIDO NA PETICAO NO 020050153908/RJ DE 28/12/2005, ESCLARECA DIVERGENCIA ENTRE O REQUERENTE E O TITULAR DO PEDIDO.

B25D Requested change of name of applicant approved

Owner name: SERONO GENETICS INSTITUTE S.A. (FR)

Free format text: ALTERADO DE: GENSET

B25G Requested change of headquarter approved

Owner name: SERONO GENETICS INSTITUTE S.A. (FR)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020050153908/RJ DE 28/12/2005.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: CONFORME ARTIGO 10O DA RESOLUCAO 124/06, CABE SER ARQUIVADO REFERENTE AO NAO RECOLHIMENTO DA 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.