BR0116332A - Processo para o aumento da estabilidade - Google Patents

Processo para o aumento da estabilidade

Info

Publication number
BR0116332A
BR0116332A BR0116332-9A BR0116332A BR0116332A BR 0116332 A BR0116332 A BR 0116332A BR 0116332 A BR0116332 A BR 0116332A BR 0116332 A BR0116332 A BR 0116332A
Authority
BR
Brazil
Prior art keywords
increased stability
composition
stabilizing
contacting
ethylene oxide
Prior art date
Application number
BR0116332-9A
Other languages
English (en)
Other versions
BRPI0116332B8 (pt
BR0116332B1 (pt
Inventor
Andrea Fetz
Gyorgy Lajos
Michel Pepiot
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8170784&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0116332(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR0116332A publication Critical patent/BR0116332A/pt
Publication of BR0116332B1 publication Critical patent/BR0116332B1/pt
Publication of BRPI0116332B8 publication Critical patent/BRPI0116332B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A61L2/206—Ethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"PROCESSO PARA O AUMENTO DA ESTABILIDADE". A presente invenção refere-se de forma específica a um método para a estabilização de uma composição farmacêutica através do contato da referida composição com um material polimérico que compreende de forma específica uma etapa de esterilização com óxido de etileno.
BRPI0116332A 2000-12-22 2001-12-20 “método para aumentar a estabilidade de uma composição farmacêutica compreendendo cetotifeno, processo para produção da dita composição e uso de um recipiente de pe” BRPI0116332B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00128318 2000-12-22
EP00128318.3 2000-12-22
PCT/EP2001/015126 WO2002051452A1 (en) 2000-12-22 2001-12-20 Process to improve stability of a pharmaceutical composition

Publications (3)

Publication Number Publication Date
BR0116332A true BR0116332A (pt) 2004-03-02
BR0116332B1 BR0116332B1 (pt) 2014-08-19
BRPI0116332B8 BRPI0116332B8 (pt) 2021-06-22

Family

ID=8170784

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0116332A BRPI0116332B8 (pt) 2000-12-22 2001-12-20 “método para aumentar a estabilidade de uma composição farmacêutica compreendendo cetotifeno, processo para produção da dita composição e uso de um recipiente de pe”

Country Status (15)

Country Link
US (4) US20040063607A1 (pt)
EP (1) EP1349580B2 (pt)
JP (1) JP4125957B2 (pt)
CN (1) CN100396334C (pt)
AR (1) AR032381A1 (pt)
AT (1) ATE367831T1 (pt)
BR (1) BRPI0116332B8 (pt)
CA (1) CA2431906A1 (pt)
CY (1) CY1106919T1 (pt)
DE (1) DE60129597T3 (pt)
DK (1) DK1349580T4 (pt)
ES (1) ES2287173T5 (pt)
PT (1) PT1349580E (pt)
TW (1) TW586946B (pt)
WO (1) WO2002051452A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
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PT1321144E (pt) * 2000-09-13 2011-03-10 Santen Pharmaceutical Co Ltd Colírio
JP4694773B2 (ja) * 2003-06-06 2011-06-08 ロート製薬株式会社 粘膜適用液状組成物
US20060199863A1 (en) * 2003-07-31 2006-09-07 Santen Pharmaceutical Co., Ltd. Product containing prostaglandin
CA2590277C (en) * 2004-12-09 2014-07-08 Santen Pharmaceutical Co., Ltd. Product containing prostaglandin having fluorine atom in its molecule
DK1829545T3 (da) * 2004-12-24 2012-07-23 Santen Pharmaceutical Co Ltd Produkter indeholdende prostaglandin-F2alfa-derivat
US20060140820A1 (en) 2004-12-28 2006-06-29 Udo Mattern Use of a container of an inorganic additive containing plastic material
KR20140083056A (ko) 2006-03-17 2014-07-03 존슨 앤드 존슨 비젼 케어, 인코포레이티드 산화에 불안정한 성분을 포함하는 안정화된 안과용 조성물
DK2068825T3 (da) 2006-10-04 2011-05-16 M & P Patent Ag Kontrolleret frisætningstilførselssystem til nasal påføring af neurotransmittere
EP2127638A1 (en) 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma
RU2482851C2 (ru) * 2009-02-20 2013-05-27 Микро Лабс Лимитед Хранение стабильного продукта простагландина
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
EP2269575A1 (en) 2009-06-30 2011-01-05 Santen Pharmaceutical Co., Ltd Method for improving bioavailability of latanoprost
US20130040923A1 (en) 2011-05-13 2013-02-14 Trimel Pharmaceuticals Corporation Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
US20130045958A1 (en) 2011-05-13 2013-02-21 Trimel Pharmaceuticals Corporation Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
US9757388B2 (en) 2011-05-13 2017-09-12 Acerus Pharmaceuticals Srl Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels
MX2014012461A (es) * 2012-04-19 2015-01-12 Bard Inc C R Soluciones intravenosas con estabilidad de ph mejorada bajo esterilizacion con oxido de etileno.
US11744838B2 (en) 2013-03-15 2023-09-05 Acerus Biopharma Inc. Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event
CN105073109B (zh) 2013-03-29 2019-03-22 株式会社AskAt 眼部疾病用治疗剂
WO2018235935A1 (ja) * 2017-06-23 2018-12-27 参天製薬株式会社 水溶性粘稠化剤を含有する医薬組成物
JP7037349B2 (ja) * 2017-06-23 2022-03-16 参天製薬株式会社 水溶性粘稠化剤を含有する医薬組成物
KR20200035047A (ko) * 2017-08-03 2020-04-01 산텐 세이야꾸 가부시키가이샤 클로르헥시딘을 함유하는 의약 조성물
MX388336B (es) * 2019-09-06 2025-03-19 Sophia Holdings S A De C V Composicion farmacéutica oftálmica, procesos de preparación y usos de las mismas
EP4183415A4 (en) 2020-07-16 2024-07-17 RaQualia Pharma Inc. Trpv4 inhibitor as therapeutic drug for eye disease
US20240156724A1 (en) * 2021-03-16 2024-05-16 Vyluma Inc. Multi-Dose Container for Ophthalmic Compositions
US12233049B2 (en) * 2021-11-15 2025-02-25 Slayback Pharma Llc Stable pharmaceutical compositions of clonidine
JP2024043685A (ja) * 2022-09-20 2024-04-02 参天製薬株式会社 ジクアホソルまたはその塩を含有する眼科用組成物のｐＨの低下を抑制する方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE523577A (pt) * 1952-10-16
GB1107600A (en) † 1965-12-15 1968-03-27 U M P Venesta Ltd Improvements relating to collapsible tubular containers
CH483963A (fr) * 1968-01-11 1970-01-15 U M P Venesta Ltd Récipient tubulaire souple
NL7009539A (pt) * 1969-07-07 1971-01-11
US3728839A (en) * 1971-04-29 1973-04-24 American Cyanamid Co Storage stable surgically absorbable polyglycolic acid products
US4482585A (en) * 1982-06-11 1984-11-13 Toppan Printing Co., Ltd. Container resistant to extremely low temperatures
US5382406A (en) * 1990-04-17 1995-01-17 Abbott Laboratories Sterile filling method
JP3256997B2 (ja) † 1990-08-30 2002-02-18 千寿製薬株式会社 安定な水性製剤
US5620425A (en) * 1993-11-03 1997-04-15 Bracco International B.V. Method for the preparation of pre-filled plastic syringes
US5749203A (en) * 1994-09-23 1998-05-12 Kimberly-Clark Corporation Method of packaging a medical article
SE515221C2 (sv) * 1996-03-20 2001-07-02 Scandimed Internat Ab Förfarande för framställning av och anordning vid en förpackning med en sterilt förpackad behållare med sterilt innehåll
US6132679A (en) * 1997-12-24 2000-10-17 Alliedsignal, Inc. Method and apparatus for aerating chemically-sterilized articles
US6475434B1 (en) * 1998-12-07 2002-11-05 Baylor College Of Medicine Composition and methods for preventing and removing biofilm embedded microorganisms from the surface of medical devices
US6440364B1 (en) * 1999-02-16 2002-08-27 Ethicon, Inc. Method of degassing absorbable suture products
US6231810B1 (en) * 1999-04-21 2001-05-15 Stryker Technologies Corporation Special cycle for ethylene oxide sterilization
EP1181197B1 (en) * 1999-05-28 2003-10-08 Novartis AG Package for a pharmaceutical product and method of sterilising the package

Also Published As

Publication number Publication date
ES2287173T3 (es) 2007-12-16
US20130097969A1 (en) 2013-04-25
US20080300277A1 (en) 2008-12-04
EP1349580B2 (en) 2012-07-04
US20040063607A1 (en) 2004-04-01
JP4125957B2 (ja) 2008-07-30
DE60129597D1 (de) 2007-09-06
CN1481259A (zh) 2004-03-10
ES2287173T5 (es) 2012-10-03
DK1349580T3 (da) 2007-10-01
ATE367831T1 (de) 2007-08-15
CY1106919T1 (el) 2012-09-26
JP2004516099A (ja) 2004-06-03
CA2431906A1 (en) 2002-07-04
DE60129597T2 (de) 2008-04-17
BRPI0116332B8 (pt) 2021-06-22
EP1349580A1 (en) 2003-10-08
BR0116332B1 (pt) 2014-08-19
CN100396334C (zh) 2008-06-25
PT1349580E (pt) 2007-10-25
DE60129597T3 (de) 2012-11-29
TW586946B (en) 2004-05-11
US20110173928A1 (en) 2011-07-21
AR032381A1 (es) 2003-11-05
WO2002051452A1 (en) 2002-07-04
EP1349580B1 (en) 2007-07-25
DK1349580T4 (da) 2012-10-08

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 19/08/2014, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/12/2001, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 21A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2703 DE 25-10-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.