BR9909329A - Método para estabilizar composições farmacêuticas pelo uso especial de um antioxidante - Google Patents

Método para estabilizar composições farmacêuticas pelo uso especial de um antioxidante

Info

Publication number
BR9909329A
BR9909329A BR9909329-4A BR9909329A BR9909329A BR 9909329 A BR9909329 A BR 9909329A BR 9909329 A BR9909329 A BR 9909329A BR 9909329 A BR9909329 A BR 9909329A
Authority
BR
Brazil
Prior art keywords
antioxidant
pharmaceutical compositions
special use
stabilizing pharmaceutical
stabilizing
Prior art date
Application number
BR9909329-4A
Other languages
English (en)
Inventor
Gyoergy Lajos Kis
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR9909329A publication Critical patent/BR9909329A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: <B>"MéTODO PARA ESTABILIZAR COMPOSIçõES FARMACêUTICAS MEDIANTE USO ESPECIAL DE UM ANTIOXIDANTE"<D>. A presente invenção descreve, em particular, um método para estabilizar uma composição farmacêutica mediante contato da referida composição com um material polimérico compreendendo um antioxidante.
BR9909329-4A 1998-04-02 1999-03-31 Método para estabilizar composições farmacêuticas pelo uso especial de um antioxidante BR9909329A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98106046 1998-04-02
PCT/EP1999/002221 WO1999051230A1 (en) 1998-04-02 1999-03-31 Method for stabilizing pharmaceutical compositions by special use of an antioxidant

Publications (1)

Publication Number Publication Date
BR9909329A true BR9909329A (pt) 2000-12-12

Family

ID=8231706

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9909329-4A BR9909329A (pt) 1998-04-02 1999-03-31 Método para estabilizar composições farmacêuticas pelo uso especial de um antioxidante

Country Status (21)

Country Link
US (2) US6576649B1 (pt)
EP (1) EP1098649B1 (pt)
JP (1) JP2002510627A (pt)
KR (1) KR100617430B1 (pt)
CN (1) CN1138542C (pt)
AT (1) ATE269079T1 (pt)
AU (1) AU756000B2 (pt)
BR (1) BR9909329A (pt)
CA (1) CA2326137C (pt)
CZ (1) CZ301851B6 (pt)
DE (1) DE69918122T2 (pt)
DK (1) DK1098649T3 (pt)
ES (1) ES2224651T3 (pt)
HU (1) HU226588B1 (pt)
ID (1) ID26033A (pt)
IL (2) IL138476A0 (pt)
NO (1) NO332004B1 (pt)
NZ (1) NZ507026A (pt)
PL (1) PL194914B1 (pt)
WO (1) WO1999051230A1 (pt)
ZA (1) ZA200005098B (pt)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0938896A1 (en) * 1998-01-15 1999-09-01 Novartis AG Autoclavable pharmaceutical compositions containing a chelating agent
US6235781B1 (en) 1998-07-14 2001-05-22 Alcon Laboratories, Inc. Prostaglandin product
PT1239732E (pt) * 1999-12-21 2004-08-31 Dsm Ip Assets Bv Conservacao da actividade de um fungicida numa solucao aquosa
US6395756B2 (en) 1999-12-23 2002-05-28 Novartis Ag Use of ophthalmic agent
KR100355892B1 (ko) * 2000-01-06 2002-10-12 주식회사 코리아나화장품 레티놀과 테트라디부틸 펜타에리스리틸히드록시히드로신나메이트를 함유하는 화장료 조성물
JP4822609B2 (ja) * 2000-05-22 2011-11-24 クラレメディカル株式会社 抗菌性組成物
CN1177002C (zh) * 2000-05-22 2004-11-24 可乐丽股份有限公司 抗菌性组合物
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
DE10041479A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923
ES2396598T3 (es) * 2000-08-25 2013-02-22 Senju Pharmaceutical Co., Ltd. Preparaciones en forma de suspensiones acuosas
US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
US20030027793A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal treatment of parkinson's disease
AU2002345015A1 (en) * 2001-06-08 2002-12-23 Novartis Pharma Gmbh Ophthalmic once-a-day composition
US7479507B2 (en) * 2003-01-14 2009-01-20 Adam Heller Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs
US6933289B2 (en) * 2003-07-01 2005-08-23 Allergan, Inc. Inhibition of irritating side effects associated with use of a topical ophthalmic medication
US20050220742A1 (en) * 2004-03-31 2005-10-06 Breen Ed V Compositions and methods for maintaining eyelid hygiene
US6969706B1 (en) * 2004-05-12 2005-11-29 Allergan, Inc. Preserved pharmaceutical compositions comprising cyclodextrins
CN1737047B (zh) * 2004-08-19 2010-05-05 住友化学株式会社 含填充材料的聚烯烃树脂组合物及其成形品
US20070208058A1 (en) * 2004-10-25 2007-09-06 Bryant Roy W Stable Pharmaceutical Compositions and Methods of Making and Using Same
CN101087607B (zh) * 2004-10-25 2010-07-28 博士伦公司 眼用组合物及使用其的方法
US20060089384A1 (en) * 2004-10-25 2006-04-27 Minno George E Ophthalmic compositions and methods of using the same
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
KR101454674B1 (ko) 2006-03-17 2014-10-27 존슨 앤드 존슨 비젼 케어, 인코포레이티드 산화에 불안정한 성분을 포함하는 안정화된 안과용 조성물
KR20140100553A (ko) * 2006-07-10 2014-08-14 존슨 앤드 존슨 비젼 케어, 인코포레이티드 약제학적 제제를 함유하는 안과용 렌즈를 위한 패키지
EP2471507B1 (en) * 2006-09-29 2017-03-01 Johnson & Johnson Vision Care, Inc. Ophthalmic devices used in the treatment of ocular allergies
US20090005362A1 (en) * 2007-06-26 2009-01-01 Vo Toan P Compositions Comprising Antihistamines or Mast Cell Stabilizers, and Methods of Making and Using Same
US8986728B2 (en) 2008-05-30 2015-03-24 Abbott Cardiovascular Systems Inc. Soluble implantable device comprising polyelectrolyte with hydrophobic counterions
US8300252B2 (en) * 2008-06-18 2012-10-30 Livescribe, Inc. Managing objects with varying and repeated printed positioning information
WO2009157586A1 (ja) * 2008-06-27 2009-12-30 祐徳薬品工業株式会社 フェンタニルまたはその塩含有経皮吸収型貼付剤
KR20100023538A (ko) * 2008-08-22 2010-03-04 삼성전자주식회사 고상 시약의 제조방법 및 고상 시약을 수용하는 미세유동장치
WO2010047681A1 (en) * 2008-10-24 2010-04-29 Bridge Pharma, Inc. Treating xerophthalmia with norketotifen
WO2010059894A1 (en) * 2008-11-21 2010-05-27 Bridge Pharma, Inc. Ocular formulations of norketotifen
KR101013102B1 (ko) * 2008-12-08 2011-02-14 주식회사 케이에스비 토너 카트리지의 블레이드 용접 장치
JP5675183B2 (ja) * 2009-06-16 2015-02-25 ロート製薬株式会社 水性組成物
FR2961694B1 (fr) * 2010-06-29 2013-01-25 Thea Lab Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur
JP2018533629A (ja) * 2015-11-06 2018-11-15 アキュイティス ファーマシューティカルズ、インコーポレイテッド 眼障害を治療するためのプロテアソーム阻害剤の使用
CN114262476B (zh) * 2021-12-30 2023-09-05 沈阳兴齐眼药股份有限公司 提高妥布霉素滴眼液稳定性的包装容器
CN114262477B (zh) * 2021-12-30 2023-09-19 沈阳兴齐眼药股份有限公司 抑制妥布霉素滴眼液变色的包装容器及其制备方法
CN114441691B (zh) * 2022-04-12 2022-08-23 广州国标检验检测有限公司 一种眼用制剂容器中塑料添加剂的检测方法
CA3264067A1 (en) 2022-08-04 2024-02-08 Bausch + Lomb Ireland Limited OPHTHALMIC COMPOSITION COMPRISING PILOCARPINE AND A REDNESS-REDUCING AGENT
WO2024028815A1 (en) 2022-08-04 2024-02-08 Bausch + Lomb Ireland Limited Ophthalmic composition comprising an anti-allergen and a redness reduction agent

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966905A (en) * 1973-05-29 1976-06-29 Barnes-Hind Pharmaceuticals, Inc. Stabilized catechol amine solutions
FR2231377B1 (pt) * 1973-05-29 1977-11-04 Barnes Hind Pharm Inc
US4959208A (en) * 1987-10-19 1990-09-25 Ppg Industries, Inc. Active agent delivery device
JP3666884B2 (ja) * 1992-05-21 2005-06-29 日本ゼオン株式会社 医療用器材
JP3098895B2 (ja) * 1993-06-28 2000-10-16 三菱化学株式会社 液体用容器
JP3021312B2 (ja) * 1994-03-15 2000-03-15 千寿製薬株式会社 プラノプロフェンの安定化方法および安定なプラノプロフェン水性液剤
JP3055753B2 (ja) * 1994-07-05 2000-06-26 昭和薬品化工株式会社 フマル酸ケトチフェン含有点眼液
JP3693696B2 (ja) * 1994-12-15 2005-09-07 久光製薬株式会社 ケトチフェン含有経皮投与製剤
ES2144264T3 (es) * 1995-08-29 2000-06-01 Exxon Chemical Patents Inc Polipropileno tolerante a la radiacion y sus articulos utiles.
KR100228514B1 (ko) * 1996-09-05 1999-11-01 한승수 비스테로이드성 소염진통제를 활성성분으로 하는 경피흡수제제의 제조방법

Also Published As

Publication number Publication date
AU756000B2 (en) 2003-01-02
EP1098649A1 (en) 2001-05-16
US6576649B1 (en) 2003-06-10
PL343156A1 (en) 2001-07-30
EP1098649B1 (en) 2004-06-16
DE69918122D1 (de) 2004-07-22
CN1138542C (zh) 2004-02-18
IL138476A0 (en) 2001-10-31
HUP0101582A3 (en) 2002-10-28
US6455547B1 (en) 2002-09-24
KR100617430B1 (ko) 2006-08-31
CA2326137A1 (en) 1999-10-14
CA2326137C (en) 2009-06-02
DK1098649T3 (da) 2004-10-04
JP2002510627A (ja) 2002-04-09
IL138476A (en) 2006-04-10
AU3811999A (en) 1999-10-25
NO332004B1 (no) 2012-05-21
CZ301851B6 (cs) 2010-07-07
DE69918122T2 (de) 2005-06-16
ZA200005098B (en) 2001-05-21
ES2224651T3 (es) 2005-03-01
HU226588B1 (en) 2009-04-28
US20020103196A1 (en) 2002-08-01
NZ507026A (en) 2003-09-26
PL194914B1 (pl) 2007-07-31
HUP0101582A2 (hu) 2002-03-28
WO1999051230A1 (en) 1999-10-14
NO20004872L (no) 2000-11-09
ID26033A (id) 2000-11-16
ATE269079T1 (de) 2004-07-15
KR20010042361A (ko) 2001-05-25
CN1295474A (zh) 2001-05-16
CZ20003579A3 (cs) 2001-01-17
NO20004872D0 (no) 2000-09-28

Similar Documents

Publication Publication Date Title
BR9909329A (pt) Método para estabilizar composições farmacêuticas pelo uso especial de um antioxidante
BR0215405A (pt) Composições e processos de uso de collajolie
BR0009486B1 (pt) composto que compreende uma amida, composição farmacêutica que compreende esse composto, seu uso e processo para a preparação do mesmo.
SV2004001432A (es) 2-tio-3,5-diciano-4-4fenil-6-aminopiridinas substituidas y su uso ref. lea 35 640-sv
BR0305074A (pt) Composições cosméticas com alta afinidade
BR0100046A (pt) Copolìmeros reticulados solúveis em água ou intumescìveis em água
BR9911182B1 (pt) compostos derivados de biarila com propriedades agonistas de adrenorreceptores beta-3, uso de um composto, composição farmacêutica, e, processo para a preparação de um composto.
BRPI0414539A (pt) composto, composição farmacêutica, e, uso de um composto
BRPI0412029A (pt) formulações para microprojeções revestidas contendo contra-ìons não-voláteis
ATE312843T1 (de) Neues cyclosporin mit verbesserter wirkung
EA200100773A1 (ru) Замещенные 1-гетероциклические диариламины
BR9910611A (pt) Composição de catalisador para polimerizar monÈmeros
BR0317392A (pt) Formulação não-higroscópica incluindo uma droga higroscópica
GT199900102A (es) Fenoxipropanolaminas, procedimiento para su preparacìon y composiciones farmacèuticasque las contienen.
BR0116332A (pt) Processo para o aumento da estabilidade
BR9911987A (pt) Compostos de reação de amina que compreende um ou mais ingredientes ativos
CA2338684A1 (en) Injectable propofol formulations
EA200001039A1 (ru) Кальцилитические соединения
DE60223542D1 (de) Zusammensetzung mit fulvestrant
BR9902377A (pt) Composição para toner e processos para a mesma.
BR9808729A (pt) Processo para a preparação de um anti-oxidante
BR9917244B1 (pt) processos para polimerização de uma olefina e/ou uma olefina e pelo menos uma ou mais outra(s) olefina(s) e para redução da carga eletrostática gerada na polimerização de uma olefina e/ou uma olefina e pelo menos uma ou mais outra(s) olefina(s).
CO5580729A2 (es) Composiciones nutricionales que comprenden cistationina
BR9713176A (pt) Benzotiofenos amorfos,métodos de preparação e métodos de uso
BR9813728A (pt) Composição de dispersão molecular com elevada biodisponibilidade

Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11 E 13 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]