BR0211729A - Compostos, composições farmacêuticas, processo para fabricar compostos, uso de um ou mais compostos, e, processo para fabricar composições farmacêuticas - Google Patents

Compostos, composições farmacêuticas, processo para fabricar compostos, uso de um ou mais compostos, e, processo para fabricar composições farmacêuticas

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Publication number
BR0211729A
BR0211729A BR0211729-0A BR0211729A BR0211729A BR 0211729 A BR0211729 A BR 0211729A BR 0211729 A BR0211729 A BR 0211729A BR 0211729 A BR0211729 A BR 0211729A
Authority
BR
Brazil
Prior art keywords
compounds
pharmaceutical compositions
manufacturing
preparation
relates
Prior art date
Application number
BR0211729-0A
Other languages
English (en)
Inventor
Martin Bolli
Christoph Boss
Martine Clozel
Walter Fischli
Thomas Weller
Judith Marfurt
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8164539&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0211729(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of BR0211729A publication Critical patent/BR0211729A/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
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    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract

"COMPOSTOS, COMPOSIçõES FARMACêUTICAS, PROCESSO PARA FABRICAR COMPOSTOS, USO DE UM OU MAIS COMPOSTOS, E, PROCESSO PARA FABRICAR COMPOSIçõES FARMACêUTICAS". A invenção diz respeito a novos heterociclos benzo-fundidos de estrutura (I), e seu uso como ingredientes na preparação de composições farmacêuticas. A invenção também diz respeito a aspectos relacionados que incluem processos para a preparação dos compostos, composições farmacêuticas contendo um ou mais destes compostos e, especialmente, a seu uso como antagonistas do receptor da endotelina. Fórmula (I)
BR0211729-0A 2001-08-09 2002-07-31 Compostos, composições farmacêuticas, processo para fabricar compostos, uso de um ou mais compostos, e, processo para fabricar composições farmacêuticas BR0211729A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP0109235 2001-08-09
PCT/EP2002/008523 WO2003013545A1 (en) 2001-08-09 2002-07-31 Novel benzo-fused heterocycles as endothelin antagonisits

Publications (1)

Publication Number Publication Date
BR0211729A true BR0211729A (pt) 2004-08-24

Family

ID=8164539

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211729-0A BR0211729A (pt) 2001-08-09 2002-07-31 Compostos, composições farmacêuticas, processo para fabricar compostos, uso de um ou mais compostos, e, processo para fabricar composições farmacêuticas

Country Status (15)

Country Link
US (1) US7238685B2 (pt)
JP (1) JP4364637B2 (pt)
KR (1) KR100909122B1 (pt)
CN (1) CN100418955C (pt)
AR (1) AR036386A1 (pt)
AU (1) AU2002328999B8 (pt)
BR (1) BR0211729A (pt)
CA (1) CA2454417A1 (pt)
HU (1) HUP0401107A3 (pt)
IL (1) IL159963A0 (pt)
MX (1) MXPA04001252A (pt)
NO (1) NO20040563L (pt)
NZ (1) NZ530741A (pt)
WO (1) WO2003013545A1 (pt)
ZA (1) ZA200400803B (pt)

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WO2003013545A1 (en) 2003-02-20
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JP4364637B2 (ja) 2009-11-18
AU2002328999B8 (en) 2008-06-05
US7238685B2 (en) 2007-07-03
KR100909122B1 (ko) 2009-07-23
CN1538848A (zh) 2004-10-20
JP2005502644A (ja) 2005-01-27
CA2454417A1 (en) 2003-02-20
US20050124605A1 (en) 2005-06-09
CN100418955C (zh) 2008-09-17
ZA200400803B (en) 2005-05-03
NZ530741A (en) 2006-08-31
HUP0401107A3 (en) 2004-10-28
AR036386A1 (es) 2004-09-08
KR20040030937A (ko) 2004-04-09
HUP0401107A2 (hu) 2004-08-30
NO20040563L (no) 2004-03-08
IL159963A0 (en) 2004-06-20

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