BR0308506A - Método para analisar concentrações de moléculas de coenzima a nas amostras biológicas - Google Patents

Método para analisar concentrações de moléculas de coenzima a nas amostras biológicas

Info

Publication number
BR0308506A
BR0308506A BR0308506-6A BR0308506A BR0308506A BR 0308506 A BR0308506 A BR 0308506A BR 0308506 A BR0308506 A BR 0308506A BR 0308506 A BR0308506 A BR 0308506A
Authority
BR
Brazil
Prior art keywords
coenzyme
molecules
biological samples
analyzing
concentrations
Prior art date
Application number
BR0308506-6A
Other languages
English (en)
Inventor
Mitsuru Sakai
Yoshinori Sugimoto
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of BR0308506A publication Critical patent/BR0308506A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G01N33/5735—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes co-enzymes or co-factors, e.g. NAD or ATP
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N2030/062—Preparation extracting sample from raw material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"MéTODO PARA ANALISAR CONCENTRAçõES DE MOLéCULAS DE COENZIMA A NAS AMOSTRAS BIOLóGICAS". A invenção é destinada a fornecer um método altamente sensível e altamente reprodutível para análise de coenzimas A (CoA) em uma amostra biológica caracterizado pelo fato de envolver a etapa de extrair a amostra biológica mediante o uso de uma solução fortemente ácida, a etapa de extração na fase sólida, a etapa de adicionar um padrão interno, e a etapa de detecção com o uso de LC-MS.
BR0308506-6A 2002-03-25 2003-03-24 Método para analisar concentrações de moléculas de coenzima a nas amostras biológicas BR0308506A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002082821 2002-03-25
PCT/JP2003/003521 WO2003081229A1 (fr) 2002-03-25 2003-03-24 Technique de dosage de coenzymes dans un echantillon biologique

Publications (1)

Publication Number Publication Date
BR0308506A true BR0308506A (pt) 2004-12-21

Family

ID=28449161

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0308506-6A BR0308506A (pt) 2002-03-25 2003-03-24 Método para analisar concentrações de moléculas de coenzima a nas amostras biológicas

Country Status (10)

Country Link
US (1) US20050118666A1 (pt)
EP (1) EP1489411A4 (pt)
JP (1) JP3780283B2 (pt)
KR (1) KR20040094856A (pt)
CN (1) CN1329730C (pt)
AU (1) AU2003221008B2 (pt)
BR (1) BR0308506A (pt)
CA (1) CA2480306A1 (pt)
MX (1) MXPA04008788A (pt)
WO (1) WO2003081229A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8530182B2 (en) * 2007-12-05 2013-09-10 Centers For Disease Control And Prevention Viral protein quantification process and vaccine quality control therewith
JP5624709B2 (ja) * 2008-03-13 2014-11-12 大日本住友製薬株式会社 内因性代謝物の分析方法
JP5325973B2 (ja) * 2009-03-05 2013-10-23 株式会社日立ハイテクノロジーズ 分析装置
US8993254B2 (en) 2009-10-29 2015-03-31 Saitama Medical University Methods for evaluating risk of mother's milk or food inducing an onset of atopic dermatitis, and mother's milk or food with reduced risk of inducing an onset of atopic dermatitis
JP6311387B2 (ja) * 2014-03-26 2018-04-18 株式会社島津製作所 化合物分析方法、化合物分析装置、及び化合物分析用プログラム
CN106324165A (zh) * 2015-07-02 2017-01-11 中国科学院大连化学物理研究所 一种微量细胞培养液中离脂肪酸的测定方法
CN107515261A (zh) * 2017-08-18 2017-12-26 开封康诺药业有限公司 一种高效液相色谱法测定辅酶i的方法
CN109270202B (zh) * 2018-10-11 2020-12-01 中国药科大学 一种动物肝脏内乙酰辅酶a的液质联用测定方法
AU2021254287A1 (en) * 2020-04-09 2022-11-10 HepQuant, LLC Improved methods for evaluating liver function
CN115407002B (zh) * 2021-05-28 2025-01-03 中国科学院遗传与发育生物学研究所 一种检测植物材料中植物内源小肽激素的纯化富集方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338686A (en) * 1992-04-29 1994-08-16 Hellerstein Marc K Method for measuring in vivo synthesis of biopolymers
WO1998055632A1 (en) * 1997-06-05 1998-12-10 Calgene Llc FATTY ACYL-CoA: FATTY ALCOHOL ACYLTRANSFERASES
US6670194B1 (en) * 1998-08-25 2003-12-30 University Of Washington Rapid quantitative analysis of proteins or protein function in complex mixtures
US6391649B1 (en) * 1999-05-04 2002-05-21 The Rockefeller University Method for the comparative quantitative analysis of proteins and other biological material by isotopic labeling and mass spectroscopy

Also Published As

Publication number Publication date
JPWO2003081229A1 (ja) 2005-07-28
CN1329730C (zh) 2007-08-01
AU2003221008B2 (en) 2007-08-16
CN1643375A (zh) 2005-07-20
WO2003081229A1 (fr) 2003-10-02
KR20040094856A (ko) 2004-11-10
JP3780283B2 (ja) 2006-05-31
US20050118666A1 (en) 2005-06-02
EP1489411A4 (en) 2007-03-14
AU2003221008A1 (en) 2003-10-08
CA2480306A1 (en) 2003-10-02
EP1489411A1 (en) 2004-12-22
MXPA04008788A (es) 2005-06-20

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 7A. E 8A. ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2125 DE 27/09/2011.