BR0308768A - Sacarìdeos modificados possuindo estabilidade melhorada em água - Google Patents

Sacarìdeos modificados possuindo estabilidade melhorada em água

Info

Publication number
BR0308768A
BR0308768A BR0308768-9A BR0308768A BR0308768A BR 0308768 A BR0308768 A BR 0308768A BR 0308768 A BR0308768 A BR 0308768A BR 0308768 A BR0308768 A BR 0308768A
Authority
BR
Brazil
Prior art keywords
improved water
water stability
modified
modified saccharides
polysaccharide
Prior art date
Application number
BR0308768-9A
Other languages
English (en)
Inventor
Paolo Costantino
Francesco Berti
Francesco Norelli
Antonella Bartoloni
Original Assignee
Chiron Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0207117A external-priority patent/GB0207117D0/en
Priority claimed from GB0220195A external-priority patent/GB0220195D0/en
Priority claimed from GB0229494A external-priority patent/GB0229494D0/en
Priority claimed from GB0230163A external-priority patent/GB0230163D0/en
Application filed by Chiron Srl filed Critical Chiron Srl
Publication of BR0308768A publication Critical patent/BR0308768A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"SACARìDEOS MODIFICADOS POSSUINDO ESTABILIDADE MELHORADA EM áGUA". Um polissacarídeo modificado, particularmente, um polissacarídeo de Neisseria meningitidis do sorogrupo A, que retém a imunogenicidade mas possui estabilidade melhorada. Tipicamente, o polissacarídeo modificado é preparado reagindo-se um polissacarídeo capsular, ou fragmento de oligossacarídeo deste, com um reagente bifuncional tal como CDI, seguida pela reação com um composto, tal como dimetilamina. Conjugados de polissacarídeo modificado-proteína e vacinas preparadas a partir de tais conjugados são também descritos.
BR0308768-9A 2002-03-26 2003-03-26 Sacarìdeos modificados possuindo estabilidade melhorada em água BR0308768A (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0207117A GB0207117D0 (en) 2002-03-26 2002-03-26 Modified saccharides having improved stability in water
GB0220195A GB0220195D0 (en) 2002-08-30 2002-08-30 Modified saccharides having improved stability in water
GB0229494A GB0229494D0 (en) 2002-12-18 2002-12-18 Modified saccharides having improved stability in water
GB0230163A GB0230163D0 (en) 2002-12-24 2002-12-24 Modified saccharides having improved stability in water
PCT/IB2003/001436 WO2003080678A1 (en) 2002-03-26 2003-03-26 Modified saccharides having improved stability in water

Publications (1)

Publication Number Publication Date
BR0308768A true BR0308768A (pt) 2005-02-15

Family

ID=28457825

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0308768-9A BR0308768A (pt) 2002-03-26 2003-03-26 Sacarìdeos modificados possuindo estabilidade melhorada em água

Country Status (14)

Country Link
EP (2) EP1490409B1 (pt)
JP (2) JP2005526153A (pt)
AT (1) ATE419278T1 (pt)
BR (1) BR0308768A (pt)
CA (1) CA2480389C (pt)
CY (2) CY1108911T1 (pt)
DE (1) DE60325565D1 (pt)
DK (2) DK1777236T3 (pt)
ES (2) ES2616180T3 (pt)
HU (1) HUE030532T2 (pt)
MX (1) MXPA04009339A (pt)
NZ (1) NZ535968A (pt)
PT (2) PT1777236T (pt)
WO (1) WO2003080678A1 (pt)

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GB0822633D0 (en) 2008-12-11 2009-01-21 Novartis Ag Formulation
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Also Published As

Publication number Publication date
ES2616180T3 (es) 2017-06-09
DE60325565D1 (de) 2009-02-12
JP2005526153A (ja) 2005-09-02
EP1777236A1 (en) 2007-04-25
CY1118584T1 (el) 2017-07-12
ATE419278T1 (de) 2009-01-15
NZ535968A (en) 2006-08-31
AU2003216633A1 (en) 2003-10-08
DK1777236T3 (en) 2017-02-27
JP5361767B2 (ja) 2013-12-04
EP1777236B1 (en) 2016-11-30
JP2010132925A (ja) 2010-06-17
EP1490409B1 (en) 2008-12-31
PT1490409E (pt) 2009-04-03
HUE030532T2 (en) 2017-05-29
DK1490409T3 (da) 2009-03-23
MXPA04009339A (es) 2005-01-25
ES2318117T3 (es) 2009-05-01
CA2480389A1 (en) 2003-10-02
PT1777236T (pt) 2017-02-13
WO2003080678A1 (en) 2003-10-02
EP1490409A1 (en) 2004-12-29
CA2480389C (en) 2012-10-09
CY1108911T1 (el) 2014-07-02
EP1777236B8 (en) 2017-02-22

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.