BR0314280A - Composto; método de tratamento de um indivìduo acometido por uma condição de depressão, ansiedade, distúrbios do pânico, de tensão pós-traumática, disfórico pré-menstrual, de deficiência da atenção, obsessivos-compulsivos e alimentares, obesidade, rubor vasomotor, dependência de álcool e cocaìna e disfunção sexual; composição farmacêutica e uso do mesmo - Google Patents
Composto; método de tratamento de um indivìduo acometido por uma condição de depressão, ansiedade, distúrbios do pânico, de tensão pós-traumática, disfórico pré-menstrual, de deficiência da atenção, obsessivos-compulsivos e alimentares, obesidade, rubor vasomotor, dependência de álcool e cocaìna e disfunção sexual; composição farmacêutica e uso do mesmoInfo
- Publication number
- BR0314280A BR0314280A BR0314280-9A BR0314280A BR0314280A BR 0314280 A BR0314280 A BR 0314280A BR 0314280 A BR0314280 A BR 0314280A BR 0314280 A BR0314280 A BR 0314280A
- Authority
- BR
- Brazil
- Prior art keywords
- disorder
- depression
- anxiety
- tension
- obsessive
- Prior art date
Links
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 title abstract 4
- 208000019901 Anxiety disease Diseases 0.000 title abstract 3
- 230000036506 anxiety Effects 0.000 title abstract 3
- 208000019906 panic disease Diseases 0.000 title abstract 3
- 208000007848 Alcoholism Diseases 0.000 title abstract 2
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 title abstract 2
- 208000030814 Eating disease Diseases 0.000 title abstract 2
- 208000019454 Feeding and Eating disease Diseases 0.000 title abstract 2
- 208000008589 Obesity Diseases 0.000 title abstract 2
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 title abstract 2
- 201000001880 Sexual dysfunction Diseases 0.000 title abstract 2
- 229960003920 cocaine Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 235000014632 disordered eating Nutrition 0.000 title abstract 2
- 238000011010 flushing procedure Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 235000020824 obesity Nutrition 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 231100000872 sexual dysfunction Toxicity 0.000 title abstract 2
- 230000001457 vasomotor Effects 0.000 title abstract 2
- 208000027030 Premenstrual dysphoric disease Diseases 0.000 title 1
- 201000007930 alcohol dependence Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 4
- 208000035475 disorder Diseases 0.000 abstract 3
- 230000001544 dysphoric effect Effects 0.000 abstract 2
- 208000000103 Anorexia Nervosa Diseases 0.000 abstract 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 abstract 1
- 241001555645 Bulimina Species 0.000 abstract 1
- 206010068631 Childhood depression Diseases 0.000 abstract 1
- 208000022497 Cocaine-Related disease Diseases 0.000 abstract 1
- 208000011688 Generalised anxiety disease Diseases 0.000 abstract 1
- 206010036618 Premenstrual syndrome Diseases 0.000 abstract 1
- 206010041250 Social phobia Diseases 0.000 abstract 1
- 208000015802 attention deficit-hyperactivity disease Diseases 0.000 abstract 1
- 201000006145 cocaine dependence Diseases 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 206010013663 drug dependence Diseases 0.000 abstract 1
- 208000024732 dysthymic disease Diseases 0.000 abstract 1
- 208000029364 generalized anxiety disease Diseases 0.000 abstract 1
- 208000013403 hyperactivity Diseases 0.000 abstract 1
- 208000035231 inattentive type attention deficit hyperactivity disease Diseases 0.000 abstract 1
- 208000024714 major depressive disease Diseases 0.000 abstract 1
- 230000002175 menstrual effect Effects 0.000 abstract 1
- 230000001568 sexual effect Effects 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
"COMPOSTO; MéTODO DE TRATAMENTO DE UM INDIVìDUO ACOMETIDO POR UMA CONDIçãO DE DEPRESSãO, ANSIEDADE, DISTúRBIOS DO PâNICO, DE TENSãO PóS-TRAUMáTICA, DISFóRICO PRé-MENSTRUAL, DE DEFICIêNCIA DA ATENçãO, OBSESSIVOS-COMPULSIVOS E ALIMENTARES, OBESIDADE, RUBOR VASOMOTOR, DEPENDêNCIA DE áLCOOL E COCAìNA E DISFUNçãO SEXUAL; COMPOSIçãO FARMACêUTICA E USO DO MESMO". Trata-se de compostos da fórmula I, úteis para o tratamento da depressão (inclusive sem caráter limitativo, distúrbios de depressão maior, depressão na infância e distimia) , ansiedade, distúrbio do pânico, distúrbio de tensão pós-traumática, distúrbio disfórico pré-menstrual (conhecido também como síndrome pré-menstrual), distúrbio de deficiência da atenção (com e sem hiper-atividade), distúrbio obsessivo-compulsivo, distúrbio de ansiedade social, distúrbio de ansiedade generalizada, obesidade, distúrbios alimentares, tais como anorexia nervosa e bulimina nervosa, rubor vasomotor, vício por cocaína e álcool, disfunção sexual e enfermidades associadas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41016902P | 2002-09-12 | 2002-09-12 | |
| PCT/US2003/028296 WO2004024723A1 (en) | 2002-09-12 | 2003-09-11 | Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0314280A true BR0314280A (pt) | 2005-07-26 |
Family
ID=31994080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0314280-9A BR0314280A (pt) | 2002-09-12 | 2003-09-11 | Composto; método de tratamento de um indivìduo acometido por uma condição de depressão, ansiedade, distúrbios do pânico, de tensão pós-traumática, disfórico pré-menstrual, de deficiência da atenção, obsessivos-compulsivos e alimentares, obesidade, rubor vasomotor, dependência de álcool e cocaìna e disfunção sexual; composição farmacêutica e uso do mesmo |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7041697B2 (pt) |
| EP (1) | EP1537103A1 (pt) |
| JP (1) | JP2006503037A (pt) |
| CN (1) | CN1681807A (pt) |
| AU (1) | AU2003267082A1 (pt) |
| BR (1) | BR0314280A (pt) |
| CA (1) | CA2498010A1 (pt) |
| MX (1) | MXPA05002740A (pt) |
| WO (1) | WO2004024723A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7041697B2 (en) * | 2002-09-12 | 2006-05-09 | Wyeth | Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan |
| AR060493A1 (es) * | 2006-04-18 | 2008-06-18 | Wyeth Corp | Derivados de benzodioxano y benzodioxolano. procesos de obtencion. |
| US20090291976A1 (en) * | 2006-06-27 | 2009-11-26 | Peter Andrew Ferchmin | Neuronal circuit-dependent neuroprotection by interaction between nicotinic receptors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK280193B6 (sk) * | 1992-04-07 | 1999-09-10 | Pfizer Inc. | Indolové deriváty predstavujúce 5-ht1 agonisty, fa |
| US5468767A (en) * | 1994-01-06 | 1995-11-21 | Bristol-Myers Squibb Company | Antidepressant 3-(aminocycloalkenyl)-indole-5-nitrile derivatives |
| US6006677A (en) * | 1998-01-08 | 1999-12-28 | Rehrig Pacific Company, Inc. | Plastic pallet |
| JP2002510676A (ja) * | 1998-04-08 | 2002-04-09 | アメリカン・ホーム・プロダクツ・コーポレイション | うつ病治療用のｎ−アリールオキシエチルアミン誘導体 |
| CN1304409A (zh) * | 1998-04-08 | 2001-07-18 | 美国家用产品公司 | 用于治疗抑郁症的吲哚－3－基－环己胺衍生物(5－ht1受体拮抗剂) |
| US7041697B2 (en) * | 2002-09-12 | 2006-05-09 | Wyeth | Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan |
-
2003
- 2003-09-10 US US10/659,193 patent/US7041697B2/en not_active Expired - Fee Related
- 2003-09-11 BR BR0314280-9A patent/BR0314280A/pt not_active IP Right Cessation
- 2003-09-11 CA CA002498010A patent/CA2498010A1/en not_active Abandoned
- 2003-09-11 JP JP2004536411A patent/JP2006503037A/ja active Pending
- 2003-09-11 AU AU2003267082A patent/AU2003267082A1/en not_active Abandoned
- 2003-09-11 CN CNA038216663A patent/CN1681807A/zh active Pending
- 2003-09-11 WO PCT/US2003/028296 patent/WO2004024723A1/en not_active Ceased
- 2003-09-11 MX MXPA05002740A patent/MXPA05002740A/es active IP Right Grant
- 2003-09-11 EP EP03749557A patent/EP1537103A1/en not_active Withdrawn
-
2006
- 2006-03-10 US US11/373,666 patent/US7488751B2/en not_active Expired - Fee Related
- 2006-03-10 US US11/372,716 patent/US20060160881A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20060148881A1 (en) | 2006-07-06 |
| EP1537103A1 (en) | 2005-06-08 |
| US20040127543A1 (en) | 2004-07-01 |
| CN1681807A (zh) | 2005-10-12 |
| CA2498010A1 (en) | 2004-03-25 |
| US20060160881A1 (en) | 2006-07-20 |
| US7041697B2 (en) | 2006-05-09 |
| MXPA05002740A (es) | 2005-06-03 |
| US7488751B2 (en) | 2009-02-10 |
| AU2003267082A1 (en) | 2004-04-30 |
| WO2004024723A1 (en) | 2004-03-25 |
| JP2006503037A (ja) | 2006-01-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012. |