BR0318443A - proteìnas solúveis em ácido de caseìna micelar - Google Patents
proteìnas solúveis em ácido de caseìna micelarInfo
- Publication number
- BR0318443A BR0318443A BRPI0318443-9A BR0318443A BR0318443A BR 0318443 A BR0318443 A BR 0318443A BR 0318443 A BR0318443 A BR 0318443A BR 0318443 A BR0318443 A BR 0318443A
- Authority
- BR
- Brazil
- Prior art keywords
- micellar casein
- acid soluble
- casein acid
- soluble proteins
- casein
- Prior art date
Links
- 239000005018 casein Substances 0.000 title abstract 6
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 title abstract 6
- 235000021240 caseins Nutrition 0.000 title abstract 6
- 235000018102 proteins Nutrition 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 239000002253 acid Substances 0.000 title abstract 3
- 235000013336 milk Nutrition 0.000 abstract 3
- 239000008267 milk Substances 0.000 abstract 3
- 210000004080 milk Anatomy 0.000 abstract 3
- 102100025101 GATA-type zinc finger protein 1 Human genes 0.000 abstract 1
- 101710198884 GATA-type zinc finger protein 1 Proteins 0.000 abstract 1
- DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000020477 pH reduction Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/04—Animal proteins
- A23J3/08—Dairy proteins
- A23J3/10—Casein
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4732—Casein
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
"PROTEìNAS SOLúVEIS EM áCIDO DE CASEìNA MICELAR". A presente invenção diz respeito a uma fração de leite obtenível por acidificação de caseína micelar e separação de caseína precipitada nomeada proteína solúvel em ácido de caseína micelar. Foi observado que a fração de leite e especialmente certas sub-frações deste são bioativas e promovem liberação de GLP-1 in vitro. Com base nestes resultados, proteína solúvel em ácido de caseína micelar pode ser útil no tratamento e na prevenção de diabetes do tipo ll, obesidade e pode também ser adicionada às fórmulas direcionadas a outros propósitos referindo ao trato gastrintestinal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2003/009669 WO2005021589A1 (en) | 2003-08-30 | 2003-08-30 | Acid soluble proteins from micellar casein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0318443A true BR0318443A (pt) | 2006-08-01 |
Family
ID=34259107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0318443-9A BR0318443A (pt) | 2003-08-30 | 2003-08-30 | proteìnas solúveis em ácido de caseìna micelar |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7629442B2 (pt) |
| JP (1) | JP2007525404A (pt) |
| CN (1) | CN1860131A (pt) |
| AU (1) | AU2003270130A1 (pt) |
| BR (1) | BR0318443A (pt) |
| CA (1) | CA2538507A1 (pt) |
| IL (1) | IL173945A0 (pt) |
| WO (1) | WO2005021589A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101272803B (zh) * | 2005-09-30 | 2012-11-21 | 森永乳业株式会社 | 胰高血糖素样肽-1分泌促进剂、胰高血糖素样肽-1分泌促进用饮食品、餐后血糖值上升抑制剂和餐后血糖值上升抑制用饮食品 |
| CN102378632A (zh) | 2009-04-03 | 2012-03-14 | 雀巢产品技术援助有限公司 | 对促进健康的追赶生长的改进 |
| EP2286679A1 (en) * | 2009-08-19 | 2011-02-23 | Nestec S.A. | Proteose peptone and lipase activity |
| EP2583562A1 (en) * | 2011-10-21 | 2013-04-24 | Nestec S.A. | Use of whey protein micelles for infants at risk of obesity or diabetes |
| EP3590519A4 (en) | 2017-03-03 | 2020-12-16 | Morinaga Milk Industry Co., Ltd. | GLP-1 SECRETAGOGUE AND COMPOSITION |
| BE1026671B1 (nl) * | 2018-10-03 | 2020-05-05 | Maeyer Stefan De | Samenstelling van een speculaas bevattende melkhoudende drank en werkwijze om deze te bereiden |
| JP2024544249A (ja) * | 2021-12-15 | 2024-11-28 | フリースランドカンピーナ ネーデルランド ベスローテン フェンノートシャップ | 免疫グロブリン富化乳画分 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2673374A1 (fr) * | 1991-03-01 | 1992-09-04 | Oreal | Composition cosmetique contenant comme ingredient actif un peptide a activite opiouide. |
| NL1005037C2 (nl) | 1997-01-17 | 1998-07-20 | Nl Zuivelonderzoek Inst | Werkwijze voor het selectief afbreken van melkeiwit, in het bijzonder voor het selectief hydrolyseren van caseïne/caseïnaat in aanwezigheid van andere melkeiwitten, in het bijzonder wei-eiwitten. |
| GB9927603D0 (en) | 1999-11-22 | 2000-01-19 | Nestle Sa | Use of a milk protein hydrolysate in the treatment of diabetes |
| DE60227922D1 (de) * | 2002-05-27 | 2008-09-11 | Nestec Sa | Säurelösliche Proteine aus Casein-Micellen |
-
2003
- 2003-08-30 BR BRPI0318443-9A patent/BR0318443A/pt not_active IP Right Cessation
- 2003-08-30 AU AU2003270130A patent/AU2003270130A1/en not_active Abandoned
- 2003-08-30 US US10/570,184 patent/US7629442B2/en not_active Expired - Lifetime
- 2003-08-30 CA CA002538507A patent/CA2538507A1/en not_active Abandoned
- 2003-08-30 JP JP2005508360A patent/JP2007525404A/ja active Pending
- 2003-08-30 CN CNA03827177XA patent/CN1860131A/zh active Pending
- 2003-08-30 WO PCT/EP2003/009669 patent/WO2005021589A1/en not_active Ceased
-
2006
- 2006-02-26 IL IL173945A patent/IL173945A0/en unknown
-
2009
- 2009-10-23 US US12/604,741 patent/US8686116B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7629442B2 (en) | 2009-12-08 |
| JP2007525404A (ja) | 2007-09-06 |
| US8686116B2 (en) | 2014-04-01 |
| CA2538507A1 (en) | 2005-03-10 |
| IL173945A0 (en) | 2006-07-05 |
| US20100111933A1 (en) | 2010-05-06 |
| US20060276632A1 (en) | 2006-12-07 |
| WO2005021589A1 (en) | 2005-03-10 |
| AU2003270130A1 (en) | 2005-03-16 |
| CN1860131A (zh) | 2006-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 3A E 7A A NUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2082 DE 30/11/2010. |
|
| B15K | Others concerning applications: alteration of classification |
Ipc: A23J 3/10 (2006.01), A23L 33/19 (2016.01), C07K 14 |