BR1100548KB1 - processes for the preparation of crystalline n-acetyl neuraminic acid derivatives. - Google Patents

processes for the preparation of crystalline n-acetyl neuraminic acid derivatives.

Info

Publication number: BR1100548KB1
Authority: BR; Brazil
Prior art keywords: crystalline; processes; preparation; acid derivatives; neuraminic acid
Prior art date: 1993-12-17

Application number

BRPP1100548-KB1A

Other languages

Portuguese (pt)

Inventor

Christopher Williamson

William James White

Vipulkumar Patel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-17

Filing date

1997-05-13

Publication date

2011-11-01

1997-05-13 Application filed filed Critical

2011-11-01 Publication of BR1100548KB1 publication Critical patent/BR1100548KB1/en

Links

SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical class CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BRPP1100548-KB1A 1993-12-17 1997-05-13 processes for the preparation of crystalline n-acetyl neuraminic acid derivatives. BR1100548KB1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB939325841A GB9325841D0 (en)	1993-12-17	1993-12-17	Chemical compounds

Publications (1)

Publication Number	Publication Date
BR1100548KB1 true BR1100548KB1 (en)	2011-11-01

Family

ID=10746778

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BR9408340A BR9408340A (en)	1993-12-17	1994-12-15	5-acetamido-2,3,4,5-tetradeoxy-4-guanidino-d-glycero-d-glacto-non-2-enotyranosonic acid form critaline process for the preparation of these and pharmaceutical formulation
BRPP1100548-KB1A BR1100548KB1 (en)	1993-12-17	1997-05-13	processes for the preparation of crystalline n-acetyl neuraminic acid derivatives.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
BR9408340A BR9408340A (en)	1993-12-17	1994-12-15	5-acetamido-2,3,4,5-tetradeoxy-4-guanidino-d-glycero-d-glacto-non-2-enotyranosonic acid form critaline process for the preparation of these and pharmaceutical formulation

Country Status (43)

Country	Link
US (2)	US6294572B1 (en)
EP (1)	EP0734382B1 (en)
JP (1)	JP3317972B2 (en)
KR (1)	KR100403256B1 (en)
CN (2)	CN1132829C (en)
AP (2)	AP541A (en)
AT (1)	ATE199255T1 (en)
BG (1)	BG63338B1 (en)
BR (2)	BR9408340A (en)
CA (1)	CA2177990C (en)
CO (1)	CO4340619A1 (en)
CZ (1)	CZ289234B6 (en)
DE (1)	DE69426726T2 (en)
DK (1)	DK0734382T3 (en)
EE (1)	EE03353B1 (en)
EG (1)	EG20597A (en)
ES (1)	ES2155517T3 (en)
FI (1)	FI120453B (en)
GB (1)	GB9325841D0 (en)
GR (1)	GR3035681T3 (en)
HR (1)	HRP941001B1 (en)
HU (1)	HU221971B1 (en)
IL (1)	IL112011A (en)
IS (1)	IS4240A (en)
MA (1)	MA23396A1 (en)
MY (1)	MY116221A (en)
NO (1)	NO314759B1 (en)
NZ (1)	NZ277789A (en)
OA (2)	OA10325A (en)
PE (1)	PE31095A1 (en)
PL (1)	PL186384B1 (en)
PT (1)	PT734382E (en)
RO (1)	RO114792B1 (en)
RU (1)	RU2134690C1 (en)
SA (1)	SA94150417B1 (en)
SG (1)	SG46669A1 (en)
SI (1)	SI0734382T1 (en)
SK (1)	SK282972B6 (en)
SV (1)	SV1994000076A (en)
TW (1)	TW452577B (en)
UA (1)	UA46723C2 (en)
WO (1)	WO1995016680A1 (en)
ZA (1)	ZA9410003B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9325841D0 (en) *	1993-12-17	1994-02-23	Glaxo Group Ltd	Chemical compounds
US5952375A (en)	1995-02-27	1999-09-14	Gilead Sciences, Inc.	Compounds and methods for synthesis and therapy
US5866601A (en) *	1995-02-27	1999-02-02	Gilead Sciences, Inc.	Carbocyclic compounds
US5763483A (en) *	1995-12-29	1998-06-09	Gilead Sciences, Inc.	Carbocyclic compounds
ATE211468T1 (en) *	1996-07-22	2002-01-15	Sankyo Co	NEURAMIC ACID DERIVATIVES, THEIR PRODUCTION AND MEDICAL USE
US6340702B1 (en)	1996-07-22	2002-01-22	Sankyo Company, Limited	Neuraminic acid derivatives, their preparation and their medical use
US6451766B1 (en)	1996-07-22	2002-09-17	Sankyo Company, Limited	Neuraminic acid derivatives, their preparation and their medical use
US5859284A (en) *	1996-08-23	1999-01-12	Gilead Sciences, Inc.	Preparation of carbocyclic compounds
US6518438B2 (en)	1996-08-23	2003-02-11	Gilead Sciences, Inc.	Preparation of cyclohexene carboxylate derivatives
US5994377A (en)	1996-10-21	1999-11-30	Gilead Sciences, Inc.	Piperidine compounds
US5886213A (en) *	1997-08-22	1999-03-23	Gilead Sciences, Inc.	Preparation of carbocyclic compounds
TW477783B (en) *	1997-12-12	2002-03-01	Gilead Sciences Inc	Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
TWI291462B (en)	2000-04-25	2007-12-21	Daiichi Sankyo Co Ltd	Hydrate crystal of neuraminic acid compound
US20080063722A1 (en) *	2006-09-08	2008-03-13	Advanced Inhalation Research, Inc.	Composition of a Spray-Dried Powder for Pulmonary Delivery of a Long Acting Neuraminidase Inhibitor (LANI)
ES2640001T3 (en) *	2011-12-16	2017-10-31	Daiichi Sankyo Company, Limited	Production procedure of a derivative of neuraminic acid
CN109232677B (en) *	2018-10-18	2021-12-28	中国科学院合肥物质科学研究院	Method for converting N-acetylneuraminic acid hydrate into N-acetylneuraminic acid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU469694A1 (en) *	1972-12-22	1975-05-05	Московский Ордена Трудового Красного Знамени Институт Тонкой Химической Технологии Им.М.В.Ломоносова	The method of obtaining 2-alkoxy-6-alkyl (aryl) - -dihydropyran
CZ288492B6 (en) *	1990-04-24	2001-06-13	Biota Scient Management	Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon
CA2081068C (en) *	1991-10-23	2005-11-29	Laurence Mark Von Itzstein	Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid
GB9126725D0 (en) *	1991-12-17	1992-02-12	Glaxo Group Ltd	Process
US5639786A (en)	1992-12-04	1997-06-17	Biota Scientific Management, Pty., Ltd.	Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of α-D-neuraninic acid
GB9325841D0 (en) *	1993-12-17	1994-02-23	Glaxo Group Ltd	Chemical compounds

1993
- 1993-12-17 GB GB939325841A patent/GB9325841D0/en active Pending
1994
- 1994-12-02 TW TW083111229A patent/TW452577B/en not_active IP Right Cessation
- 1994-12-13 IS IS4240A patent/IS4240A/en unknown
- 1994-12-15 KR KR1019960703180A patent/KR100403256B1/en not_active Expired - Lifetime
- 1994-12-15 WO PCT/EP1994/004154 patent/WO1995016680A1/en not_active Ceased
- 1994-12-15 PT PT95904472T patent/PT734382E/en unknown
- 1994-12-15 ES ES95904472T patent/ES2155517T3/en not_active Expired - Lifetime
- 1994-12-15 PE PE1994257245A patent/PE31095A1/en not_active Application Discontinuation
- 1994-12-15 MA MA23724A patent/MA23396A1/en unknown
- 1994-12-15 CO CO94056728A patent/CO4340619A1/en unknown
- 1994-12-15 SK SK785-96A patent/SK282972B6/en not_active IP Right Cessation
- 1994-12-15 RO RO96-01195A patent/RO114792B1/en unknown
- 1994-12-15 CA CA002177990A patent/CA2177990C/en not_active Expired - Lifetime
- 1994-12-15 MY MYPI94003357A patent/MY116221A/en unknown
- 1994-12-15 PL PL94315055A patent/PL186384B1/en unknown
- 1994-12-15 BR BR9408340A patent/BR9408340A/en not_active Application Discontinuation
- 1994-12-15 SG SG1996007725A patent/SG46669A1/en unknown
- 1994-12-15 EG EG79094A patent/EG20597A/en active
- 1994-12-15 AT AT95904472T patent/ATE199255T1/en active
- 1994-12-15 CN CN94194973A patent/CN1132829C/en not_active Expired - Lifetime
- 1994-12-15 HU HU9601642A patent/HU221971B1/en active IP Right Grant
- 1994-12-15 DK DK95904472T patent/DK0734382T3/en active
- 1994-12-15 SI SI9430333T patent/SI0734382T1/en unknown
- 1994-12-15 AP APAP/P/1994/000705A patent/AP541A/en active
- 1994-12-15 ZA ZA9410003A patent/ZA9410003B/en unknown
- 1994-12-15 SV SV1994000076A patent/SV1994000076A/en active IP Right Grant
- 1994-12-15 EP EP95904472A patent/EP0734382B1/en not_active Expired - Lifetime
- 1994-12-15 CN CNA2003101199989A patent/CN1502621A/en active Pending
- 1994-12-15 AP APAP/P/1996/000810A patent/AP9600810A0/en unknown
- 1994-12-15 CZ CZ19961693A patent/CZ289234B6/en not_active IP Right Cessation
- 1994-12-15 UA UA96062328A patent/UA46723C2/en unknown
- 1994-12-15 NZ NZ277789A patent/NZ277789A/en not_active IP Right Cessation
- 1994-12-15 DE DE69426726T patent/DE69426726T2/en not_active Expired - Lifetime
- 1994-12-15 HR HR941001A patent/HRP941001B1/en not_active IP Right Cessation
- 1994-12-15 RU RU96115122A patent/RU2134690C1/en active Protection Beyond IP Right Term
- 1994-12-15 JP JP51653195A patent/JP3317972B2/en not_active Expired - Lifetime
- 1994-12-15 EE EE9600135A patent/EE03353B1/en unknown
- 1994-12-16 IL IL11201194A patent/IL112011A/en not_active IP Right Cessation
- 1994-12-28 SA SA94150417A patent/SA94150417B1/en unknown
1996
- 1996-06-13 FI FI962464A patent/FI120453B/en not_active IP Right Cessation
- 1996-06-14 OA OA60842A patent/OA10325A/en unknown
- 1996-06-14 NO NO19962545A patent/NO314759B1/en not_active IP Right Cessation
- 1996-07-08 BG BG100709A patent/BG63338B1/en unknown
1997
- 1997-05-13 BR BRPP1100548-KB1A patent/BR1100548KB1/en unknown
1999
- 1999-07-02 US US09/346,583 patent/US6294572B1/en not_active Expired - Lifetime
2000
- 2000-01-06 OA OA1200000004A patent/OA11275A/en unknown
2001
- 2001-03-30 GR GR20010400531T patent/GR3035681T3/en unknown
- 2001-09-24 US US09/961,074 patent/US20020037865A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE69426726D1 (en)	2001-03-29
BG63338B1 (en)	2001-10-31
EG20597A (en)	1999-09-30
CA2177990C (en)	2000-04-25
OA11275A (en)	2002-11-20
GB9325841D0 (en)	1994-02-23
NZ277789A (en)	1999-04-29
RU2134690C1 (en)	1999-08-20
DK0734382T3 (en)	2001-03-19
JP3317972B2 (en)	2002-08-26
HK1014187A1 (en)	1999-09-24
EP0734382B1 (en)	2001-02-21
EE03353B1 (en)	2001-02-15
HU221971B1 (en)	2003-03-28
HU9601642D0 (en)	1996-08-28
SI0734382T1 (en)	2001-08-31
CO4340619A1 (en)	1996-07-30
DE69426726T2 (en)	2001-06-21
CN1142820A (en)	1997-02-12
MY116221A (en)	2003-12-31
SK78596A3 (en)	1997-03-05
OA10325A (en)	1997-10-07
SK282972B6 (en)	2003-01-09
JPH09506601A (en)	1997-06-30
BR9408340A (en)	1997-08-19
KR100403256B1 (en)	2004-04-30
SA94150417B1 (en)	2005-12-18
US20020037865A1 (en)	2002-03-28
RO114792B1 (en)	1999-07-30
HUT74938A (en)	1997-03-28
CZ169396A3 (en)	1996-11-13
FI962464A0 (en)	1996-06-13
IS4240A (en)	1995-06-18
CN1132829C (en)	2003-12-31
AU1314495A (en)	1995-07-03
FI120453B (en)	2009-10-30
PT734382E (en)	2001-06-29
NO314759B1 (en)	2003-05-19
ZA9410003B (en)	1995-07-25
AP9400705A0 (en)	1995-01-31
TW452577B (en)	2001-09-01
UA46723C2 (en)	2002-06-17
US6294572B1 (en)	2001-09-25
AU689185B2 (en)	1998-03-26
NO962545L (en)	1996-06-14
SG46669A1 (en)	1998-02-20
HRP941001A2 (en)	1997-06-30
CN1502621A (en)	2004-06-09
FI962464L (en)	1996-06-13
ATE199255T1 (en)	2001-03-15
HRP941001B1 (en)	2001-06-30
PL186384B1 (en)	2004-01-30
WO1995016680A1 (en)	1995-06-22
SV1994000076A (en)	1995-10-26
NO962545D0 (en)	1996-06-14
PE31095A1 (en)	1995-10-18
IL112011A (en)	1998-08-16
PL315055A1 (en)	1996-09-30
EP0734382A1 (en)	1996-10-02
CZ289234B6 (en)	2001-12-12
GR3035681T3 (en)	2001-06-29
IL112011A0 (en)	1995-03-15
AP9600810A0 (en)	1996-07-31
CA2177990A1 (en)	1995-06-22
AP541A (en)	1996-10-01
BG100709A (en)	1997-01-31
MA23396A1 (en)	1995-07-01
ES2155517T3 (en)	2001-05-16

Publication	Publication Date	Title
FI954250L (en)	1995-09-11	Crystalline free ceftiofuric acid
DK0797542T3 (en)	2002-05-27	Process for the preparation of aluminosilicate derivatives
MX9204546A (en)	1993-02-01	PROCESS FOR THE PREPARATION OF NATAMYCIN BY FERMENTATION.
NO900740L (en)	1990-08-17	PROCEDURE FOR SYNTHISIZING TRIS-HYDROXYMETHYL ALKANESTERS AS LOW-CALORIC FATTIMITIONS.
IS4240A (en)	1995-06-18	Crystalline N-acetyl neuraminic acid derivatives and methods for their production
MX9205455A (en)	1993-05-01	PROCEDURE FOR THE PREPARATION OF CRYSTALLINE DIRYTHROMYCIN
ES2125463T3 (en)	1999-03-01	PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF N-ACETYL NEURAMINIC ACID.
MX9204635A (en)	1993-02-01	PROCEDURE FOR THE PREPARATION OF BETA-PHENYLISOSERINE DERIVATIVES.
MX9204521A (en)	1993-02-01	PROCESS FOR THE PREPARATION OF NATAMYCIN FOR FERMENTATION (CASE CH-1898).
MA23179A1 (en)	1994-12-31	PROCESS FOR THE PREPARATION OF A CRYSTALLINE MONOHYDRATE OF A SPIROSTANYLGLYCOSIDE
BR9503565A (en)	1996-06-04	Process for the preparation of a substituted or unsubstituted quinacridone
MA22401A1 (en)	1992-10-01	PROCESS FOR THE PREPARATION OF GUINOLEIN SALTS
MA21854A1 (en)	1990-12-31	PROCESS FOR THE PREPARATION OF PHOSPHONOMETHYL THIOETHOXYPURINES.
MX9204520A (en)	1993-02-01	PROCESS FOR THE PREPARATION OF NATAMYCIN BY FERMENTATION (CASE CH 2074).
MA21657A1 (en)	1990-07-01	PROCESS FOR THE PREPARATION OF PRECURSORS OF 3-ACYL-2- OXINDOLE-1- CARBOXAMIDES SELF-INFLAMMATORY.
MX9200841A (en)	1992-09-01	IMPROVED PROCESS FOR THE PREPARATION OF DINITROTOLUENE.
DE69616554D1 (en)	2001-12-06	SIALIC ACID DERIVATIVES
FI922125A7 (en)	1992-12-22	Microbiological process for the preparation of 5-hydroxypyrazinecarboxylic acid
BR9700009A (en)	1998-11-10	Process for the preparation of o-chloromethyl-phenylglyoxylic acid derivatives
FR2728566B1 (en)	1997-01-24	PROCESS FOR THE PREPARATION OF PENTENE-NITRILES
BR9811778B1 (en)	2010-07-13	process for the preparation of 1-phenylpyrazolin-3-carboxylic acid derivatives.
FR2687153B1 (en)	1994-05-13	PROCESS FOR THE PREPARATION OF (THENYL-2) -5 HYDANTOUINE.
BR9305542A (en)	1995-12-26	Process for the preparation of 5-alkoxy-2,4-dinitro-alkylbenzenes
AU6495298A (en)	1998-08-26	Process for preparing 3-hydroxy-3-methylbutyric acid or its salts
SI0705256T1 (en)	1999-04-30	Process for the preparation of n-acetyl neuraminic acid derivatives