BR1100548KB1 - processos para a preparação de derivados de ácido n-acetil neuramìnico cristalino. - Google Patents

processos para a preparação de derivados de ácido n-acetil neuramìnico cristalino.

Info

Publication number: BR1100548KB1
Authority: BR; Brazil
Prior art keywords: crystalline; processes; preparation; acid derivatives; neuraminic acid
Prior art date: 1993-12-17

Application number

BRPP1100548-KB1A

Other languages

English (en)

Inventor

Christopher Williamson

William James White

Vipulkumar Patel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-17

Filing date

1997-05-13

Publication date

2011-11-01

1997-05-13 Application filed filed Critical

2011-11-01 Publication of BR1100548KB1 publication Critical patent/BR1100548KB1/pt

Links

SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical class CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BRPP1100548-KB1A 1993-12-17 1997-05-13 processos para a preparação de derivados de ácido n-acetil neuramìnico cristalino. BR1100548KB1 (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB939325841A GB9325841D0 (en)	1993-12-17	1993-12-17	Chemical compounds

Publications (1)

Publication Number	Publication Date
BR1100548KB1 true BR1100548KB1 (pt)	2011-11-01

Family

ID=10746778

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BR9408340A BR9408340A (pt)	1993-12-17	1994-12-15	Acido 5-acetamido-2,3,4,5-tetradeoxi-4-guanidino-d-glicero-d-glacto-não-2-enotiranosonico forma critalina processo para a preparação dos mesmos e formulação farmacêutica
BRPP1100548-KB1A BR1100548KB1 (pt)	1993-12-17	1997-05-13	processos para a preparação de derivados de ácido n-acetil neuramìnico cristalino.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
BR9408340A BR9408340A (pt)	1993-12-17	1994-12-15	Acido 5-acetamido-2,3,4,5-tetradeoxi-4-guanidino-d-glicero-d-glacto-não-2-enotiranosonico forma critalina processo para a preparação dos mesmos e formulação farmacêutica

Country Status (43)

Country	Link
US (2)	US6294572B1 (pt)
EP (1)	EP0734382B1 (pt)
JP (1)	JP3317972B2 (pt)
KR (1)	KR100403256B1 (pt)
CN (2)	CN1502621A (pt)
AP (2)	AP541A (pt)
AT (1)	ATE199255T1 (pt)
BG (1)	BG63338B1 (pt)
BR (2)	BR9408340A (pt)
CA (1)	CA2177990C (pt)
CO (1)	CO4340619A1 (pt)
CZ (1)	CZ289234B6 (pt)
DE (1)	DE69426726T2 (pt)
DK (1)	DK0734382T3 (pt)
EE (1)	EE03353B1 (pt)
EG (1)	EG20597A (pt)
ES (1)	ES2155517T3 (pt)
FI (1)	FI120453B (pt)
GB (1)	GB9325841D0 (pt)
GR (1)	GR3035681T3 (pt)
HR (1)	HRP941001B1 (pt)
HU (1)	HU221971B1 (pt)
IL (1)	IL112011A (pt)
IS (1)	IS4240A (pt)
MA (1)	MA23396A1 (pt)
MY (1)	MY116221A (pt)
NO (1)	NO314759B1 (pt)
NZ (1)	NZ277789A (pt)
OA (2)	OA10325A (pt)
PE (1)	PE31095A1 (pt)
PL (1)	PL186384B1 (pt)
PT (1)	PT734382E (pt)
RO (1)	RO114792B1 (pt)
RU (1)	RU2134690C1 (pt)
SA (1)	SA94150417B1 (pt)
SG (1)	SG46669A1 (pt)
SI (1)	SI0734382T1 (pt)
SK (1)	SK282972B6 (pt)
SV (1)	SV1994000076A (pt)
TW (1)	TW452577B (pt)
UA (1)	UA46723C2 (pt)
WO (1)	WO1995016680A1 (pt)
ZA (1)	ZA9410003B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9325841D0 (en) *	1993-12-17	1994-02-23	Glaxo Group Ltd	Chemical compounds
US5866601A (en) *	1995-02-27	1999-02-02	Gilead Sciences, Inc.	Carbocyclic compounds
CN100409844C (zh) *	1995-02-27	2008-08-13	吉里德科学公司	神经氨酸苷酶抑制剂
US5763483A (en) *	1995-12-29	1998-06-09	Gilead Sciences, Inc.	Carbocyclic compounds
US6340702B1 (en)	1996-07-22	2002-01-22	Sankyo Company, Limited	Neuraminic acid derivatives, their preparation and their medical use
DE69709795T2 (de) *	1996-07-22	2002-09-26	Sankyo Co., Ltd.	Neuraminsäuredervate, ihre Herstellung und medizinische Verwendung
US6451766B1 (en)	1996-07-22	2002-09-17	Sankyo Company, Limited	Neuraminic acid derivatives, their preparation and their medical use
US6518438B2 (en)	1996-08-23	2003-02-11	Gilead Sciences, Inc.	Preparation of cyclohexene carboxylate derivatives
US5859284A (en) *	1996-08-23	1999-01-12	Gilead Sciences, Inc.	Preparation of carbocyclic compounds
US5994377A (en)	1996-10-21	1999-11-30	Gilead Sciences, Inc.	Piperidine compounds
US5886213A (en) *	1997-08-22	1999-03-23	Gilead Sciences, Inc.	Preparation of carbocyclic compounds
TW480247B (en) *	1997-12-12	2002-03-21	Gilead Sciences Inc	Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
TWI291462B (en) *	2000-04-25	2007-12-21	Daiichi Sankyo Co Ltd	Hydrate crystal of neuraminic acid compound
US20080063722A1 (en) *	2006-09-08	2008-03-13	Advanced Inhalation Research, Inc.	Composition of a Spray-Dried Powder for Pulmonary Delivery of a Long Acting Neuraminidase Inhibitor (LANI)
EP2960237A1 (en) *	2011-12-16	2015-12-30	Daiichi Sankyo Company, Limited	Method for producing neuraminic acid derivative
CN109232677B (zh) *	2018-10-18	2021-12-28	中国科学院合肥物质科学研究院	一种使n-乙酰神经氨酸水合物转化为n-乙酰神经氨酸的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU469694A1 (ru) *	1972-12-22	1975-05-05	Московский Ордена Трудового Красного Знамени Институт Тонкой Химической Технологии Им.М.В.Ломоносова	Способ получени 2-алкокси-6-алкил (арил)- -дигидропиранов
SK282950B6 (sk) *	1990-04-24	2003-01-09	Biota Scientific Management Pty Ltd	Deriváty alfa-D-neuramínovej kyseliny, spôsob ich prípravy, ich použitie a farmaceutické prípravky na ich báze
CA2081068C (en) *	1991-10-23	2005-11-29	Laurence Mark Von Itzstein	Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid
GB9126725D0 (en) *	1991-12-17	1992-02-12	Glaxo Group Ltd	Process
US5639786A (en)	1992-12-04	1997-06-17	Biota Scientific Management, Pty., Ltd.	Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of α-D-neuraninic acid
GB9325841D0 (en) *	1993-12-17	1994-02-23	Glaxo Group Ltd	Chemical compounds

1993
- 1993-12-17 GB GB939325841A patent/GB9325841D0/en active Pending
1994
- 1994-12-02 TW TW083111229A patent/TW452577B/zh not_active IP Right Cessation
- 1994-12-13 IS IS4240A patent/IS4240A/is unknown
- 1994-12-15 BR BR9408340A patent/BR9408340A/pt not_active Application Discontinuation
- 1994-12-15 WO PCT/EP1994/004154 patent/WO1995016680A1/en not_active Ceased
- 1994-12-15 PL PL94315055A patent/PL186384B1/pl unknown
- 1994-12-15 AP APAP/P/1994/000705A patent/AP541A/en active
- 1994-12-15 UA UA96062328A patent/UA46723C2/uk unknown
- 1994-12-15 DK DK95904472T patent/DK0734382T3/da active
- 1994-12-15 SG SG1996007725A patent/SG46669A1/en unknown
- 1994-12-15 CA CA002177990A patent/CA2177990C/en not_active Expired - Lifetime
- 1994-12-15 MA MA23724A patent/MA23396A1/fr unknown
- 1994-12-15 HR HR941001A patent/HRP941001B1/xx not_active IP Right Cessation
- 1994-12-15 MY MYPI94003357A patent/MY116221A/en unknown
- 1994-12-15 CO CO94056728A patent/CO4340619A1/es unknown
- 1994-12-15 ES ES95904472T patent/ES2155517T3/es not_active Expired - Lifetime
- 1994-12-15 PT PT95904472T patent/PT734382E/pt unknown
- 1994-12-15 SV SV1994000076A patent/SV1994000076A/es active IP Right Grant
- 1994-12-15 RU RU96115122A patent/RU2134690C1/ru active Protection Beyond IP Right Term
- 1994-12-15 SK SK785-96A patent/SK282972B6/sk not_active IP Right Cessation
- 1994-12-15 SI SI9430333T patent/SI0734382T1/xx unknown
- 1994-12-15 EP EP95904472A patent/EP0734382B1/en not_active Expired - Lifetime
- 1994-12-15 CN CNA2003101199989A patent/CN1502621A/zh active Pending
- 1994-12-15 JP JP51653195A patent/JP3317972B2/ja not_active Expired - Lifetime
- 1994-12-15 EG EG79094A patent/EG20597A/xx active
- 1994-12-15 AT AT95904472T patent/ATE199255T1/de active
- 1994-12-15 NZ NZ277789A patent/NZ277789A/en not_active IP Right Cessation
- 1994-12-15 DE DE69426726T patent/DE69426726T2/de not_active Expired - Lifetime
- 1994-12-15 PE PE1994257245A patent/PE31095A1/es not_active Application Discontinuation
- 1994-12-15 CN CN94194973A patent/CN1132829C/zh not_active Expired - Lifetime
- 1994-12-15 RO RO96-01195A patent/RO114792B1/ro unknown
- 1994-12-15 EE EE9600135A patent/EE03353B1/xx unknown
- 1994-12-15 AP APAP/P/1996/000810A patent/AP9600810A0/en unknown
- 1994-12-15 ZA ZA9410003A patent/ZA9410003B/xx unknown
- 1994-12-15 KR KR1019960703180A patent/KR100403256B1/ko not_active Expired - Lifetime
- 1994-12-15 HU HU9601642A patent/HU221971B1/hu active IP Right Grant
- 1994-12-15 CZ CZ19961693A patent/CZ289234B6/cs not_active IP Right Cessation
- 1994-12-16 IL IL11201194A patent/IL112011A/en not_active IP Right Cessation
- 1994-12-28 SA SA94150417A patent/SA94150417B1/ar unknown
1996
- 1996-06-13 FI FI962464A patent/FI120453B/fi not_active IP Right Cessation
- 1996-06-14 NO NO19962545A patent/NO314759B1/no not_active IP Right Cessation
- 1996-06-14 OA OA60842A patent/OA10325A/fr unknown
- 1996-07-08 BG BG100709A patent/BG63338B1/bg unknown
1997
- 1997-05-13 BR BRPP1100548-KB1A patent/BR1100548KB1/pt unknown
1999
- 1999-07-02 US US09/346,583 patent/US6294572B1/en not_active Expired - Lifetime
2000
- 2000-01-06 OA OA1200000004A patent/OA11275A/fr unknown
2001
- 2001-03-30 GR GR20010400531T patent/GR3035681T3/el unknown
- 2001-09-24 US US09/961,074 patent/US20020037865A1/en not_active Abandoned

Also Published As

Publication number	Publication date
NZ277789A (en)	1999-04-29
FI962464L (fi)	1996-06-13
MY116221A (en)	2003-12-31
CO4340619A1 (es)	1996-07-30
EP0734382B1 (en)	2001-02-21
DE69426726T2 (de)	2001-06-21
IS4240A (is)	1995-06-18
HU221971B1 (hu)	2003-03-28
CZ289234B6 (cs)	2001-12-12
ES2155517T3 (es)	2001-05-16
SI0734382T1 (en)	2001-08-31
BG100709A (bg)	1997-01-31
DE69426726D1 (de)	2001-03-29
CA2177990A1 (en)	1995-06-22
SK282972B6 (sk)	2003-01-09
SA94150417B1 (ar)	2005-12-18
FI120453B (fi)	2009-10-30
CN1142820A (zh)	1997-02-12
NO962545L (no)	1996-06-14
PT734382E (pt)	2001-06-29
AP9400705A0 (en)	1995-01-31
EG20597A (en)	1999-09-30
JPH09506601A (ja)	1997-06-30
BG63338B1 (bg)	2001-10-31
GB9325841D0 (en)	1994-02-23
HU9601642D0 (en)	1996-08-28
ATE199255T1 (de)	2001-03-15
CN1132829C (zh)	2003-12-31
KR100403256B1 (ko)	2004-04-30
US6294572B1 (en)	2001-09-25
MA23396A1 (fr)	1995-07-01
CZ169396A3 (en)	1996-11-13
SV1994000076A (es)	1995-10-26
BR9408340A (pt)	1997-08-19
AP9600810A0 (en)	1996-07-31
AU689185B2 (en)	1998-03-26
SG46669A1 (en)	1998-02-20
OA11275A (en)	2002-11-20
AU1314495A (en)	1995-07-03
FI962464A0 (fi)	1996-06-13
GR3035681T3 (en)	2001-06-29
SK78596A3 (en)	1997-03-05
IL112011A0 (en)	1995-03-15
PL315055A1 (en)	1996-09-30
JP3317972B2 (ja)	2002-08-26
NO314759B1 (no)	2003-05-19
HUT74938A (en)	1997-03-28
US20020037865A1 (en)	2002-03-28
NO962545D0 (no)	1996-06-14
WO1995016680A1 (en)	1995-06-22
RO114792B1 (ro)	1999-07-30
PL186384B1 (pl)	2004-01-30
HRP941001B1 (en)	2001-06-30
TW452577B (en)	2001-09-01
CA2177990C (en)	2000-04-25
IL112011A (en)	1998-08-16
ZA9410003B (en)	1995-07-25
DK0734382T3 (da)	2001-03-19
HRP941001A2 (en)	1997-06-30
OA10325A (en)	1997-10-07
RU2134690C1 (ru)	1999-08-20
CN1502621A (zh)	2004-06-09
HK1014187A1 (en)	1999-09-24
EP0734382A1 (en)	1996-10-02
AP541A (en)	1996-10-01
EE03353B1 (et)	2001-02-15
UA46723C2 (uk)	2002-06-17
PE31095A1 (es)	1995-10-18

Publication	Publication Date	Title
FI960851L (fi)	1996-02-23	Menetelmä N-amino-1-hydroksi-alkylideeni-1,1-bisfosfonihappojen valmistamiseksi
BR1100548KB1 (pt)	2011-11-01	processos para a preparação de derivados de ácido n-acetil neuramìnico cristalino.
FI954250L (fi)	1995-09-11	Kiteinen vapaa keftiofuurihappo
DK0797542T3 (da)	2002-05-27	Fremgangsmåde til fremstilling af aluminosilikatderivater
MX9204546A (es)	1993-02-01	Proceso para la preparacion de natamicina por fermentacion.
NO900740L (no)	1990-08-17	Fremgangsmaate for syntetisering av tris-hydroxymethyl-alkanestere som fettimitasjoner med lavt kaloriinnhold.
MX9205455A (es)	1993-05-01	Procedimiento para la preparacion de diritromicina cristalina
ES2125463T3 (es)	1999-03-01	Procedimiento para la preparacion de derivados de acido n-acetil neuraminico.
MX9204635A (es)	1993-02-01	Procedimiento para la preparacion de derivados de beta-fenilisoserina.
MX9204521A (es)	1993-02-01	Proceso para la preparacion de natamicina por fermentacion (caso ch-1898).
MA23179A1 (fr)	1994-12-31	Procede de preparation d'un monohydrate cristallin d'un spirostanylglycoside
BR9503565A (pt)	1996-06-04	Processo para a preparação de uma quinacridona substituída ou n o substituída
MA22401A1 (fr)	1992-10-01	Procede de preparation de sels de guinoleine
MA21854A1 (fr)	1990-12-31	Procede de preparation de phosphonomethyl thioethoxypurines .
MX9204520A (es)	1993-02-01	Proceso para la preparacion de natamicina por fermentacion (caso ch 2074).
FR2626883B1 (fr)	1991-02-22	Procede de preparation de n-phosphonomethyl-imino-diacetique
MA21657A1 (fr)	1990-07-01	Procede de preparation de precurseurs des 3-acyl-2- oxindole-1- carboxamides auto-inflammatoires .
MX9200841A (es)	1992-09-01	Proceso mejorado para la preparacion de dinitrotolueno.
FI922125A7 (fi)	1992-12-22	Mikrobiologinen menetelmä 5-hydroksipyratsiinikarboksyylihapon valmistamiseksi
BR9700009A (pt)	1998-11-10	Processo para a preparação de derivados de ácido o-clorometil-fenilglioxílico
EP0641764A3 (de)	1996-03-27	Verfahren zur Herstellung von Hydroxyalkylaminonitrobenzol-Derivaten.
FR2728566B1 (fr)	1997-01-24	Procede de preparation de pentene-nitriles
FR2687153B1 (fr)	1994-05-13	Procede de preparation de la (thenyl-2)-5 hydantouine.
BR9305542A (pt)	1995-12-26	Processo para a preparação de 5-alcóxi-2,4-dinitro-alquilbenzenos
AU6495298A (en)	1998-08-26	Process for preparing 3-hydroxy-3-methylbutyric acid or its salts