BR1100756KB1 - droga profilática ou terapêutica para nefropatia ou nefrite glomerular. - Google Patents
droga profilática ou terapêutica para nefropatia ou nefrite glomerular.Info
- Publication number
- BR1100756KB1 BR1100756KB1 BRPP1100756-7KB1A BR1100756A BR1100756KB1 BR 1100756K B1 BR1100756K B1 BR 1100756KB1 BR 1100756 A BR1100756 A BR 1100756A BR 1100756K B1 BR1100756K B1 BR 1100756KB1
- Authority
- BR
- Brazil
- Prior art keywords
- stands
- prophylactic
- therapeutic drug
- nephritis
- optionally substituted
- Prior art date
Links
- 229940043274 prophylactic drug Drugs 0.000 title abstract 2
- 230000000069 prophylactic effect Effects 0.000 title abstract 2
- 229940126585 therapeutic drug Drugs 0.000 title abstract 2
- 230000001434 glomerular Effects 0.000 title 1
- 208000017169 kidney disease Diseases 0.000 title 1
- 201000008383 nephritis Diseases 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 208000007342 Diabetic Nephropathies Diseases 0.000 abstract 1
- 206010018364 Glomerulonephritis Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000033679 diabetic kidney disease Diseases 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9594293 | 1993-04-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR1100756KB1 true BR1100756KB1 (pt) | 2011-10-18 |
Family
ID=14151326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPP1100756-7KB1A BR1100756KB1 (pt) | 1993-04-22 | 1997-05-12 | droga profilática ou terapêutica para nefropatia ou nefrite glomerular. |
Country Status (12)
| Country | Link |
|---|---|
| US (7) | US5719173A (ja) |
| EP (1) | EP0622077B1 (ja) |
| JP (1) | JP3810020B2 (ja) |
| AT (1) | ATE194284T1 (ja) |
| BR (1) | BR1100756KB1 (ja) |
| CA (1) | CA2121871C (ja) |
| CY (1) | CY2204B1 (ja) |
| DE (1) | DE69425085T2 (ja) |
| DK (1) | DK0622077T3 (ja) |
| ES (1) | ES2149226T3 (ja) |
| GR (1) | GR3033862T3 (ja) |
| PT (1) | PT622077E (ja) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3810020B2 (ja) * | 1993-04-22 | 2006-08-16 | 武田薬品工業株式会社 | 腎疾患の予防または治療剤 |
| JP2003306432A (ja) * | 1993-04-22 | 2003-10-28 | Takeda Chem Ind Ltd | 腎疾患の予防または治療剤 |
| US5721263A (en) * | 1993-06-07 | 1998-02-24 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition for angiotensin II-mediated diseases |
| EP0760316B1 (en) * | 1995-02-10 | 2004-03-17 | Enshu Co., Ltd. | Seat belt suspender |
| EP0843559A2 (en) * | 1996-06-11 | 1998-05-27 | Zonagen, Inc. | Chitosan drug delivery system |
| AU5576498A (en) * | 1997-02-05 | 1998-08-26 | Sankyo Company Limited | Prophylactic or therapeutic agent for diabetic complication |
| US8273866B2 (en) * | 2002-02-20 | 2012-09-25 | Merck Sharp & Dohme Corp. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA) |
| CA2400124C (en) * | 2000-02-18 | 2010-12-14 | Kazuaki Ikeya | Tnf-.alpha. inhibitors |
| US7087608B2 (en) | 2000-03-03 | 2006-08-08 | Robert Charles Atkins | Use of PDGF receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy |
| WO2004071534A1 (ja) * | 2003-02-17 | 2004-08-26 | Takeda Pharmaceutical Company Limited | 腎疾患の予防・治療剤 |
| US7021099B2 (en) * | 2003-06-12 | 2006-04-04 | General Motors Corporation | Extraction system for hot formed parts |
| CA2547785A1 (en) * | 2003-12-19 | 2005-07-21 | Merck & Co., Inc. | Cyclic guanidines, compositions containing such compounds and methods of use |
| WO2006046528A1 (ja) * | 2004-10-29 | 2006-05-04 | Kowa Co., Ltd. | 糸球体疾患治療剤 |
| TW200719896A (en) * | 2005-04-18 | 2007-06-01 | Astrazeneca Ab | Combination product |
| AR057455A1 (es) | 2005-07-22 | 2007-12-05 | Merck & Co Inc | Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica |
| US9066936B2 (en) * | 2007-03-28 | 2015-06-30 | Takeda Pharmaceutical Company Limited | Solid pharmaceutical composition comprising a benzimidazole-7-carboxylate derivative and a pH control agent |
| JP5559696B2 (ja) * | 2008-10-22 | 2014-07-23 | 協和発酵キリン株式会社 | 糖尿病性腎症の治療剤 |
| CA2802414C (en) | 2010-06-17 | 2018-01-09 | Nitto Denko Corporation | Agent for treating renal fibrosis |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5128256A (en) * | 1987-01-12 | 1992-07-07 | Stratagene | DNA cloning vectors with in vivo excisable plasmids |
| DE3928177A1 (de) * | 1989-04-08 | 1991-02-28 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| EP0400835A1 (en) * | 1989-05-15 | 1990-12-05 | Merck & Co. Inc. | Substituted benzimidazoles as angiotensin II antagonists |
| DE69013607T2 (de) * | 1989-08-02 | 1995-03-02 | Takeda Chemical Industries Ltd | Pyrazol-Derivate, Verfahren zu deren Herstellung und Anwendung. |
| DE3927170A1 (de) * | 1989-08-17 | 1991-02-21 | Boehringer Ingelheim Kg | Inhalator |
| IL95975A (en) * | 1989-10-24 | 1997-06-10 | Takeda Chemical Industries Ltd | N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them |
| US5250554A (en) * | 1989-10-24 | 1993-10-05 | Takeda Chemical Industries, Ltd. | Benzimidazole derivatives useful as angiotensin II inhibitors |
| EP0430300A3 (en) * | 1989-12-01 | 1992-03-25 | Takeda Chemical Industries, Ltd. | Xanthine derivatives, their production and use |
| EP0434038A1 (en) * | 1989-12-22 | 1991-06-26 | Takeda Chemical Industries, Ltd. | Fused imidazole derivatives, their production and use |
| US5162326A (en) * | 1990-02-15 | 1992-11-10 | Takeda Chemical Industries, Ltd. | Pyrimidinedione derivatives, their production and use |
| US5284661A (en) * | 1990-02-22 | 1994-02-08 | Takeda Chemical Industries, Ltd. | Fused thiophene derivatives, their production and use |
| CA2037630C (en) * | 1990-03-07 | 2001-07-03 | Akira Morimoto | Nitrogen-containing heterocylic compounds, their production and use |
| US5196444A (en) * | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
| ES2121773T3 (es) * | 1990-06-08 | 1998-12-16 | Hoechst Marion Roussel Inc | Derivados de bencimidazol, su procedimiento de preparacion, productos intermedios, su aplicacion como medicamentos y composiciones farmaceuticas que los contienen. |
| JPH05509086A (ja) * | 1990-06-22 | 1993-12-16 | イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー | イミダゾールアンジオテンシン―2受容体拮抗薬による慢性腎不全の治療 |
| AU8405691A (en) * | 1990-09-04 | 1992-03-30 | Yamanouchi Pharmaceutical Co., Ltd. | Novel tetrahydrobenzazole derivative |
| AU636066B2 (en) * | 1990-10-30 | 1993-04-08 | Takeda Chemical Industries Ltd. | Thienoimidazole derivatives, their production and use |
| GB9027210D0 (en) * | 1990-12-14 | 1991-02-06 | Smithkline Beecham Plc | Medicaments |
| TW274551B (ja) * | 1991-04-16 | 1996-04-21 | Takeda Pharm Industry Co Ltd | |
| IL102183A (en) * | 1991-06-27 | 1999-11-30 | Takeda Chemical Industries Ltd | Biphenyl substituted heterocyclic compounds their production and pharmaceutical compositions comprising them |
| EP0588299B1 (en) * | 1992-09-14 | 1998-07-01 | Takeda Chemical Industries, Ltd. | 1,2,4-Oxadiazolyl- or 1,2,4-thiadiazolyl-biphenyl derivatives as angiotensin II antagonists |
| EP0603712B1 (en) * | 1992-12-22 | 2001-08-16 | Takeda Chemical Industries, Ltd. | Heterocyclic compounds having angiotensin II antagonistic activity and use thereof |
| JP3810020B2 (ja) | 1993-04-22 | 2006-08-16 | 武田薬品工業株式会社 | 腎疾患の予防または治療剤 |
-
1994
- 1994-04-20 JP JP08170594A patent/JP3810020B2/ja not_active Expired - Fee Related
- 1994-04-21 CA CA002121871A patent/CA2121871C/en not_active Expired - Fee Related
- 1994-04-21 DE DE69425085T patent/DE69425085T2/de not_active Expired - Lifetime
- 1994-04-21 AT AT94106203T patent/ATE194284T1/de active
- 1994-04-21 ES ES94106203T patent/ES2149226T3/es not_active Expired - Lifetime
- 1994-04-21 EP EP94106203A patent/EP0622077B1/en not_active Expired - Lifetime
- 1994-04-21 PT PT94106203T patent/PT622077E/pt unknown
- 1994-04-21 DK DK94106203T patent/DK0622077T3/da active
-
1996
- 1996-08-14 US US08/696,475 patent/US5719173A/en not_active Expired - Lifetime
-
1997
- 1997-05-12 BR BRPP1100756-7KB1A patent/BR1100756KB1/pt unknown
- 1997-11-06 US US08/965,416 patent/US5889036A/en not_active Expired - Lifetime
-
1998
- 1998-12-08 US US09/207,043 patent/US6040324A/en not_active Expired - Fee Related
-
1999
- 1999-12-20 US US09/467,488 patent/US6319938B1/en not_active Expired - Fee Related
-
2000
- 2000-07-06 GR GR20000401469T patent/GR3033862T3/el unknown
- 2000-12-08 CY CY0000058A patent/CY2204B1/xx unknown
-
2001
- 2001-10-16 US US09/977,476 patent/US6469037B2/en not_active Expired - Fee Related
-
2002
- 2002-08-26 US US10/227,537 patent/US6686383B2/en not_active Expired - Fee Related
-
2003
- 2003-10-02 US US10/676,118 patent/US7135490B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK0622077T3 (da) | 2000-10-23 |
| US6686383B2 (en) | 2004-02-03 |
| US20030114509A1 (en) | 2003-06-19 |
| CY2204B1 (en) | 2002-11-08 |
| EP0622077A1 (en) | 1994-11-02 |
| EP0622077B1 (en) | 2000-07-05 |
| GR3033862T3 (en) | 2000-10-31 |
| JPH072667A (ja) | 1995-01-06 |
| JP3810020B2 (ja) | 2006-08-16 |
| US6040324A (en) | 2000-03-21 |
| US6319938B1 (en) | 2001-11-20 |
| US20040082636A1 (en) | 2004-04-29 |
| ES2149226T3 (es) | 2000-11-01 |
| ATE194284T1 (de) | 2000-07-15 |
| DE69425085D1 (de) | 2000-08-10 |
| US20020045652A1 (en) | 2002-04-18 |
| CA2121871A1 (en) | 1994-10-23 |
| PT622077E (pt) | 2000-10-31 |
| DE69425085T2 (de) | 2000-11-09 |
| CA2121871C (en) | 2006-12-12 |
| US5889036A (en) | 1999-03-30 |
| US6469037B2 (en) | 2002-10-22 |
| US5719173A (en) | 1998-02-17 |
| US7135490B2 (en) | 2006-11-14 |
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