BR112021022902A2 - Métodos e composições que compreendem variantes de proteína a staphylococcus (spa) - Google Patents

Métodos e composições que compreendem variantes de proteína a staphylococcus (spa)

Info

Publication number
BR112021022902A2
BR112021022902A2 BR112021022902A BR112021022902A BR112021022902A2 BR 112021022902 A2 BR112021022902 A2 BR 112021022902A2 BR 112021022902 A BR112021022902 A BR 112021022902A BR 112021022902 A BR112021022902 A BR 112021022902A BR 112021022902 A2 BR112021022902 A2 BR 112021022902A2
Authority
BR
Brazil
Prior art keywords
spa
methods
staphylococcus
compositions
protein variants
Prior art date
Application number
BR112021022902A
Other languages
English (en)
Inventor
Dominique Missiakas
Keun Kim Hwan
Miaomiao Shi
Olaf Schneewind
Xinhai Chen
Yan Sun
Original Assignee
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Chicago filed Critical Univ Chicago
Publication of BR112021022902A2 publication Critical patent/BR112021022902A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

métodos e composições que compreendem variantes de proteína a staphylococcus (spa). as modalidades referem-se a métodos e composição para prevenir ou tratar uma infecção bacteriana, particularmente infecção por uma bactéria staphylococcus. as modalidades se referem a uma variante de proteína a (spa) não-toxigênica aperfeiçoada.
BR112021022902A 2019-05-14 2020-05-13 Métodos e composições que compreendem variantes de proteína a staphylococcus (spa) BR112021022902A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962847832P 2019-05-14 2019-05-14
PCT/US2020/070048 WO2020232471A2 (en) 2019-05-14 2020-05-13 Methods and compositions comprising staphylococcus protein a (spa) variants

Publications (1)

Publication Number Publication Date
BR112021022902A2 true BR112021022902A2 (pt) 2022-01-25

Family

ID=73288805

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021022902A BR112021022902A2 (pt) 2019-05-14 2020-05-13 Métodos e composições que compreendem variantes de proteína a staphylococcus (spa)

Country Status (15)

Country Link
US (1) US12514914B2 (pt)
EP (1) EP3969031A4 (pt)
JP (1) JP7643730B2 (pt)
KR (1) KR20220025724A (pt)
CN (1) CN114340652B (pt)
AU (1) AU2020273471B2 (pt)
BR (1) BR112021022902A2 (pt)
CA (1) CA3139981A1 (pt)
CL (1) CL2021002992A1 (pt)
CO (1) CO2021015337A2 (pt)
IL (1) IL288060A (pt)
MX (1) MX2021013833A (pt)
PH (1) PH12021552875A1 (pt)
SG (1) SG11202112479UA (pt)
WO (1) WO2020232471A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12528882B2 (en) 2019-09-13 2026-01-20 The University Of Chicago Methods and compositions for treating staphylococcal infections
WO2022212667A1 (en) * 2021-04-02 2022-10-06 Janssen Pharmaceuticals, Inc. Staphylococcus aureus vaccine compositions
CN114315996B (zh) * 2021-12-31 2023-01-17 博格隆(浙江)生物技术有限公司 一种重组ProteinA蛋白及亲和层析介质的制备方法
CN119708175A (zh) * 2023-09-28 2025-03-28 浙江壹生科生物技术有限公司 葡萄球菌蛋白a变体及其应用

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