BR112022008061A2 - Processo eficaz para síntese de 2-amino-5-cloro-n,3-dimetilbenzamida - Google Patents

Processo eficaz para síntese de 2-amino-5-cloro-n,3-dimetilbenzamida

Info

Publication number
BR112022008061A2
BR112022008061A2 BR112022008061A BR112022008061A BR112022008061A2 BR 112022008061 A2 BR112022008061 A2 BR 112022008061A2 BR 112022008061 A BR112022008061 A BR 112022008061A BR 112022008061 A BR112022008061 A BR 112022008061A BR 112022008061 A2 BR112022008061 A2 BR 112022008061A2
Authority
BR
Brazil
Prior art keywords
dimethylbenzamide
chloro
amino
synthesis
effective process
Prior art date
Application number
BR112022008061A
Other languages
English (en)
Inventor
Chen Liang
Fan Yefeng
Mao Jianhua
Xu Zhijian
Original Assignee
Fmc Corp
Fmc Agro Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp, Fmc Agro Singapore Pte Ltd filed Critical Fmc Corp
Publication of BR112022008061A2 publication Critical patent/BR112022008061A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/12—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reactions not involving the formation of oxyimino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/36—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCESSO EFICAZ PARA SÍNTESE DE 2- AMINO-5-CLORO-N,3-DIMETILBENZAMIDA. São descritos no presente documento métodos de sintetização de 2-amino-5-cloro-N,3-dimetilbenzamida. Os compostos preparados pelos métodos revelados no presente documento são úteis para preparação de certos compostos de antranilamida que são de interesse como inseticidas, como, por exemplo, os inseticidas clorantraniliprol e ciantraniliprol.
BR112022008061A 2019-11-01 2020-10-28 Processo eficaz para síntese de 2-amino-5-cloro-n,3-dimetilbenzamida BR112022008061A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962929138P 2019-11-01 2019-11-01
PCT/US2020/057726 WO2021086957A1 (en) 2019-11-01 2020-10-28 An efficient new process for synthesis of 2-amino-5-chloro-n-,3-dimethylbenzamide

Publications (1)

Publication Number Publication Date
BR112022008061A2 true BR112022008061A2 (pt) 2022-07-12

Family

ID=73543326

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022008061A BR112022008061A2 (pt) 2019-11-01 2020-10-28 Processo eficaz para síntese de 2-amino-5-cloro-n,3-dimetilbenzamida

Country Status (15)

Country Link
US (2) US11542241B2 (pt)
EP (2) EP4119542A1 (pt)
JP (3) JP7730309B2 (pt)
KR (1) KR20220091537A (pt)
CN (3) CN114080388A (pt)
AU (1) AU2020372895A1 (pt)
BR (1) BR112022008061A2 (pt)
HU (1) HUE067805T2 (pt)
IL (3) IL294707B2 (pt)
MA (1) MA56056A (pt)
MX (2) MX2022005229A (pt)
PL (1) PL3976583T3 (pt)
TW (2) TW202126616A (pt)
WO (1) WO2021086957A1 (pt)
ZA (2) ZA202204803B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021086957A1 (en) * 2019-11-01 2021-05-06 Fmc Corporation An efficient new process for synthesis of 2-amino-5-chloro-n-,3-dimethylbenzamide
WO2023073502A1 (en) * 2021-10-28 2023-05-04 Laurus Labs Limited Methods for preparation of anthranilamide and pyrazole-carboxylate intermediate compounds
TW202421613A (zh) * 2022-10-19 2024-06-01 美商富曼西公司 合成２－胺基－５－氯－ｎ，３－二甲基苯甲醯胺之高效新方法
CN115594608A (zh) * 2022-10-20 2023-01-13 九江善水科技股份有限公司（Cn） 一种氯虫苯甲酰胺中间体的制备方法
CN116730859B (zh) * 2023-06-01 2025-06-13 青岛科技大学 一种2-氨基-5-氯-n,3-二甲基苯甲酰胺的制备方法
CN116987002A (zh) * 2023-06-20 2023-11-03 湖北可赛化工有限公司 一种2-氨基-5-氯-n,3-二甲基苯甲酰胺的制备方法
WO2025134140A1 (en) * 2023-12-19 2025-06-26 Pi Industries Ltd. A method for the synthesis of substituted anthranilic amide compounds, intermediates and salts thereof
PY24113048A (es) 2023-12-19 2025-10-10 Pi Industries Ltd Un metodo para la sintesis de compuestos de amidas antranilicas sustituidas, intermediarios y sales de los mismos

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1421255A (fr) * 1962-09-18 1965-12-17 Parke Davis & Co Nouveaux anhydrides d'acides n-arylisatoïques et procédés pour leur préparation
DE2262830A1 (de) * 1972-12-22 1974-06-27 Bayer Ag Verfahren zur herstellung von oximinoacet-o-toluidid
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
CZ20013469A3 (cs) 1999-03-31 2002-04-17 Basf Aktiengesellschaft Diamidy pyridin-2,3-dikarboxylových kyselin
CA2540289A1 (en) 2003-10-02 2005-04-14 Cephalon, Inc. Substituted indole derivatives
EP1718611A4 (en) * 2004-02-13 2009-09-23 Harvard College 3-3-DI-SUBSTITUTED OXINDOLES AS INHIBITORS OF INITIATION OF TRANSLATION
TWI363756B (en) 2004-12-07 2012-05-11 Du Pont Method for preparing n-phenylpyrazole-1-carboxamides
KR101433395B1 (ko) * 2006-07-19 2014-08-26 이 아이 듀폰 디 네모아 앤드 캄파니 3-치환된 2-아미노-5-할로벤즈아미드의 제조 방법
US20110065671A1 (en) * 2008-05-19 2011-03-17 Harris Joel M Bicyclic heterocycle derivatives and use thereof as gpr119 modulators
CN101786980B (zh) * 2010-03-31 2012-12-05 滨海康杰化学有限公司 靛红衍生物的合成方法
CN102311424A (zh) * 2010-07-05 2012-01-11 温州大学 一种氯虫苯甲酰胺关键中间体的合成方法
US8440662B2 (en) * 2010-10-31 2013-05-14 Endo Pharmaceuticals, Inc. Substituted quinazoline and pyrido-pyrimidine derivatives
CN103058993B (zh) 2013-01-08 2014-06-04 河南师范大学 一种氯虫苯甲酰胺的制备方法
US9499495B2 (en) 2013-04-12 2016-11-22 Asana Biosciences, Llc Quinazolines and azaquinazolines as dual inhibitors of RAS/RAF/MEK/ERK and PI3K/AKT/PTEN/mTOR pathways
WO2017062581A1 (en) * 2015-10-06 2017-04-13 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for modulating cftr
CN105732462B (zh) * 2016-02-03 2019-01-04 常州工程职业技术学院 一种合成7-卤代吲哚的方法
WO2021086957A1 (en) * 2019-11-01 2021-05-06 Fmc Corporation An efficient new process for synthesis of 2-amino-5-chloro-n-,3-dimethylbenzamide

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Publication number Publication date
PL3976583T3 (pl) 2024-09-16
TW202408988A (zh) 2024-03-01
CN114621130A (zh) 2022-06-14
IL292210B1 (en) 2023-03-01
HUE067805T2 (hu) 2024-11-28
TW202126616A (zh) 2021-07-16
JP2023002456A (ja) 2023-01-10
EP3976583A1 (en) 2022-04-06
CN115536540A (zh) 2022-12-30
EP4119542A1 (en) 2023-01-18
CN114621130B (zh) 2025-02-25
IL313390A (en) 2024-08-01
EP3976583B1 (en) 2024-05-01
KR20220091537A (ko) 2022-06-30
US20230096826A1 (en) 2023-03-30
IL292210A (en) 2022-06-01
IL294707B2 (en) 2024-12-01
MA56056A (fr) 2022-04-06
IL294707B1 (en) 2024-08-01
MX2022005229A (es) 2022-06-08
JP7730309B2 (ja) 2025-08-27
WO2021086957A1 (en) 2021-05-06
TWI881549B (zh) 2025-04-21
AU2020372895A1 (en) 2022-05-26
US12304893B2 (en) 2025-05-20
CN115536540B (zh) 2025-03-25
IL294707A (en) 2022-09-01
MX2026001742A (es) 2026-03-02
US11542241B2 (en) 2023-01-03
ZA202204803B (en) 2024-08-28
CN114080388A (zh) 2022-02-22
JP2025061138A (ja) 2025-04-10
US20220242837A1 (en) 2022-08-04
ZA202403308B (en) 2025-08-27
IL292210B2 (en) 2023-07-01
JP2023501851A (ja) 2023-01-20

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B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B25A Requested transfer of rights approved

Owner name: FMC CORPORATION (US) ; FMC IP TECHNOLOGY GMBH (CH)